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ONTOLOGY REPORT - ANNOTATIONS

Term:execution phase of apoptosis
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Accession:GO:0097194 term browser browse the term
Definition:A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
Synonyms:exact_synonym: execution phase of apoptotic process
 narrow_synonym: apoptosis


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execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm3 apoptosis inducing factor, mitochondria associated 3 involved_in ISO
IBA		 (PMID:15764604)
GO_REF:0000033		 RGD
GO_Central		 PMID:15764604 GO_REF:0000033 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12124386)		 Ensembl
RGD		 PMID:12124386 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:11350920) RGD PMID:11350920 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IBA
IEA		 (PMID:11463392)
GO_REF:0000033
GO_REF:0000107
(PMID:11463391)		 RGD
GO_Central
Ensembl		 PMID:11463391 PMID:11463392 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Casp2 caspase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (MGI:84234|PMID:8934524)
(PMID:8934524)
MGI:109383|MGI:2651856 (PMID:11549719), (PMID:12124386), (PMID:12954857), (PMID:15456877), (PMID:16469926)
GO_REF:0000033
(PMID:11350920), (PMID:16374543), (PMID:8689682)		 RGD
GO_Central		 PMID:8689682 PMID:8934524 PMID:11350920 PMID:11549719 PMID:12124386 More... GO_REF:0000033 MGI:84234 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16374543), (PMID:16916640), (PMID:22184066), (PMID:31586028)
MGI:107739 (PMID:16469926)
GO_REF:0000033		 RGD
GO_Central		 PMID:16374543 PMID:16469926 PMID:16916640 PMID:22184066 PMID:31586028 GO_REF:0000033 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24813849), (PMID:24813850)
(MGI:5602910|PMID:24813850), (MGI:5602911|PMID:24813849)
(PMID:21737330)		 UniProt
RGD		 PMID:21737330 PMID:24813849 PMID:24813850 GO_REF:0000024 MGI:5602910 MGI:5602911 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cecr2 CECR2, histone acetyl-lysine reader involved_in ISO (PMID:12762840) RGD PMID:12762840 NCBI chr 4:153,890,310...153,998,078
Ensembl chr 4:153,890,206...153,993,451 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b involved_in ISO (MGI:1203887|PMID:9564035)
(PMID:9564035)		 RGD PMID:9564035 MGI:1203887 NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c involved_in ISO
IEA		 (PMID:12429024)
GO_REF:0000107		 RGD
Ensembl		 PMID:12429024 GO_REF:0000107 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Madd MAP-kinase activating death domain involved_in ISO (PMID:14735464)
(MGI:3700423|PMID:14735464)		 RGD PMID:14735464 MGI:3700423 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:26776679) RGD PMID:26776679 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IEA
ISO		 GO_REF:0000107
MGI:3774275 (PMID:25012822)		 Ensembl
RGD		 PMID:25012822 GO_REF:0000107 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO (PMID:12107159) RGD PMID:12107159 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS		 (PMID:16407310)
GO_REF:0000024		 RGD
UniProt		 PMID:16407310 GO_REF:0000024 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:10490026) RGD PMID:10490026 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001 		JBrowse link
G Dffb DNA fragmentation factor subunit beta involved_in ISO
IEA		 (PMID:10959840)
GO_REF:0000107		 RGD
Ensembl		 PMID:10959840 GO_REF:0000107 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (PMID:11175748) RGD PMID:11175748 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Kdm4a lysine demethylase 4A IMP RGD PMID:24747049 RGD:9587433 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Top2a DNA topoisomerase II alpha involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:10959840)		 Ensembl
GO_Central
RGD		 PMID:10959840 GO_REF:0000033 GO_REF:0000107 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
G Dffb DNA fragmentation factor subunit beta involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000002
(PMID:15572351)
(PMID:22253444)
GO_REF:0000107		 GO_Central
InterPro
RGD
Ensembl		 PMID:15572351 PMID:22253444 PMID:11425895 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:628524 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 acts_upstream_of_or_within
involved_in		 TAS
ISO
IBA		 (PMID:12050166)
GO_REF:0000033
(PMID:23229555)		 RGD
GO_Central		 PMID:12050166 PMID:23229555 PMID:9665719 GO_REF:0000033, RGD:728743 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:235,470,915...235,515,211
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
G Endog endonuclease G involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3034030|MGI:3514265 (PMID:14663139)		 GO_Central
RGD		 PMID:14663139 GO_REF:0000033 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Exog exo/endonuclease G involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Foxl2 forkhead box L2 involved_in ISO (PMID:16153597) RGD PMID:16153597 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:11403940)		 Ensembl
RGD		 PMID:11403940 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
apoptotic nuclear changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C involved_in IEA
ISO		 GO_REF:0000107
(PMID:15531507)		 Ensembl
RGD		 PMID:15531507 GO_REF:0000107 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Blcap BLCAP, apoptosis inducing factor involved_in ISO (PMID:17031575) RGD PMID:17031575 NCBI chr 3:146,222,699...146,232,859
Ensembl chr 3:146,222,240...146,232,909 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:14707049) RGD PMID:14707049 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO
IEA
ISS		 (PMID:23478299)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23478299 GO_REF:0000024 GO_REF:0000107 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO MGI:2153356 (PMID:14625552) RGD PMID:14625552 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO (PMID:11741985) RGD PMID:11741985 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:21874357 PMID:20841353 RGD:150540304, RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Sharpin SHANK-associated RH domain interactor acts_upstream_of_or_within ISO MGI:1856699 (PMID:7792947) RGD PMID:7792947 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
cellular component disassembly involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5705719|PMID:23429263)		 UniProt
RGD		 PMID:23429263 GO_REF:0000024 MGI:5705719 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha acts_upstream_of_or_within
involved_in		 ISO (PMID:15572351)
MGI:2179456 (PMID:10601318), (PMID:14663139)
(PMID:11371636)		 RGD PMID:10601318 PMID:11371636 PMID:14663139 PMID:15572351 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
G Dffb DNA fragmentation factor subunit beta involved_in ISO
IEA		 (PMID:11371636)
GO_REF:0000107		 RGD
Ensembl		 PMID:11371636 GO_REF:0000107 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IMP RGD PMID:27184051 RGD:13781945 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180 		JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pak2 p21 (RAC1) activated kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21555521)		 Ensembl
RGD		 PMID:21555521 GO_REF:0000107 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15069192)		 Ensembl
UniProt
RGD		 PMID:15069192 GO_REF:0000024 GO_REF:0000107 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15069192)		 UniProt
Ensembl
RGD		 PMID:15069192 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
negative regulation of execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS		 (PMID:20673843)
GO_REF:0000024		 RGD
UniProt		 PMID:20673843 GO_REF:0000024 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:3768618|PMID:17080483)
(PMID:17080483)		 RGD PMID:17080483 MGI:3768618 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12782716)		 UniProt
RGD		 PMID:12782716 GO_REF:0000024 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha involved_in ISO
IBA		 (PMID:9564035)
GO_REF:0000033		 RGD
GO_Central		 PMID:9564035 GO_REF:0000033 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
G Fzd3 frizzled class receptor 3 involved_in ISO (MGI:4941059|PMID:21325504)
(PMID:21325504)		 RGD PMID:21325504 MGI:4941059 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G Gcg glucagon involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19915011)		 Ensembl
RGD		 PMID:19915011 GO_REF:0000107 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Mir30b microRNA 30b involved_in ISO (PMID:23968872) RGD PMID:23968872 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
nuclear fragmentation involved in apoptotic nuclear change term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 NOT|acts_upstream_of_or_within ISO MGI:4127698 (PMID:22936354), (PMID:23532839) RGD PMID:22936354 PMID:23532839 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
(PMID:32110987)
(PMID:12509439)
GO_REF:0000033
(MGI:6450314|PMID:32110987)		 UniProt
RGD
GO_Central		 PMID:12509439 PMID:32110987 GO_REF:0000024 GO_REF:0000033 MGI:6450314 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 involved_in ISO (MGI:6450314|PMID:32110987) RGD PMID:32110987 MGI:6450314 NCBI chr  X:107,946,163...108,230,991
Ensembl chr  X:107,939,131...108,230,991 		JBrowse link
G Xkr4 XK related 4 involved_in ISO
IBA
ISS		 (MGI:6706096|PMID:33725486), (MGI:6716960|PMID:25231987)
(PMID:25231987), (PMID:33725486)
GO_REF:0000033
GO_REF:0000024
(PMID:33725486)		 RGD
GO_Central
UniProt		 PMID:25231987 PMID:33725486 GO_REF:0000024 GO_REF:0000033 MGI:6706096 MGI:6716960 NCBI chr 5:15,896,818...16,297,733
Ensembl chr 5:15,895,863...16,282,962 		JBrowse link
G Xkr6 XK related 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:37,857,096...38,059,699
Ensembl chr15:37,857,096...38,059,682 		JBrowse link
G Xkr7 XK related 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,500,908...141,525,062
Ensembl chr 3:141,501,284...141,525,062 		JBrowse link
G Xkr8 XK related 8 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:23845944)
(PMID:25231987), (PMID:30718401)
(PMID:23845944), (PMID:29440417), (PMID:31712393)
MGI:5528895 (PMID:29440417)
GO_REF:0000033
(MGI:5502792|PMID:23845944), (MGI:6435898|PMID:31712393), (MGI:6716960|PMID:25231987), (MGI:6716970|PMID:30718401)		 RGD
GO_Central		 PMID:23845944 PMID:25231987 PMID:29440417 PMID:30718401 PMID:31712393 GO_REF:0000033 MGI:5502792 MGI:6435898 MGI:6716960 MGI:6716970 NCBI chr 5:144,938,061...144,945,195
Ensembl chr 5:144,938,064...144,945,195 		JBrowse link
G Xkr9 XK related 9 involved_in ISO
IBA		 (MGI:6716960|PMID:25231987)
(PMID:25231987)
GO_REF:0000033		 RGD
GO_Central		 PMID:25231987 GO_REF:0000033 MGI:6716960 NCBI chr 5:5,530,384...5,562,168
Ensembl chr 5:5,533,416...5,562,168 		JBrowse link
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:11350920) RGD PMID:11350920 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Endog endonuclease G IMP RGD PMID:16407272 RGD:9685355 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Gata5 GATA binding protein 5 IMP RGD PMID:25726415 RGD:155260369 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IMP RGD PMID:15125883 RGD:10402776 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:28433754) RGD PMID:28433754 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
positive regulation of execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07054614.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
ISS		 (PMID:20673843)
GO_REF:0000024		 RGD
UniProt		 PMID:20673843 GO_REF:0000024 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp8 caspase 8 involved_in ISO MGI:2159369 (PMID:9729047), (PMID:9837723) RGD PMID:9729047 PMID:9837723 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO
IEA		 (PMID:17888903)
GO_REF:0000107		 RGD
Ensembl		 PMID:17888903 GO_REF:0000107 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:12887920), (PMID:8565075) RGD PMID:8565075 PMID:12887920 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fap fibroblast activation protein, alpha involved_in ISO (MGI:3047166|PMID:15133496)
(PMID:15133496)		 RGD PMID:15133496 MGI:3047166 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IDA RGD PMID:24997405 RGD:401938605 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:17297443) RGD PMID:17297443 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO UniProtKB:O43464 (PMID:17297443) RGD PMID:17297443 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11551955)		 UniProt
Ensembl
RGD		 PMID:11551955 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:19508861 RGD:151667451 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO MGI:6272324 (PMID:26555174) RGD PMID:26555174 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17521387)
GO_REF:0000107
(MGI:5572869|PMID:17521387)		 UniProt
RGD
Ensembl		 PMID:17521387 GO_REF:0000024 GO_REF:0000107 MGI:5572869 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO MGI:103290|MGI:1857468 (PMID:10678933), (PMID:10702415) RGD PMID:10678933 PMID:10702415 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (PMID:14985081)
GO_REF:0000107		 RGD
Ensembl		 PMID:14985081 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 involved_in ISO (PMID:14985081) RGD PMID:14985081 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO (MGI:5297619|PMID:21971051)
(PMID:21971051)		 RGD PMID:21971051 MGI:5297619 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
positive regulation of phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faslg Fas ligand involved_in ISO (PMID:24904167) RGD PMID:24904167 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (PMID:33725486) RGD PMID:33725486 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 acts_upstream_of_or_within ISO MGI:1306796 (PMID:15703386) RGD PMID:15703386 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO MGI:1349414 (PMID:15703386) RGD PMID:15703386 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:1203887|PMID:9564035)
(PMID:9564035)		 RGD PMID:9564035 MGI:1203887 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      execution phase of apoptosis 85
        cellular component disassembly involved in execution phase of apoptosis + 35
        negative regulation of execution phase of apoptosis + 10
        phosphatidylserine exposure on apoptotic cell surface + 10
        positive regulation of execution phase of apoptosis 18
        regulation of execution phase of apoptosis + 27
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      cell death 2179
        programmed cell death 2179
          apoptotic process 2107
            execution phase of apoptosis 85
              cellular component disassembly involved in execution phase of apoptosis + 35
              negative regulation of execution phase of apoptosis + 10
              phosphatidylserine exposure on apoptotic cell surface + 10
              positive regulation of execution phase of apoptosis 18
              regulation of execution phase of apoptosis + 27
paths to the root