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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptotic signaling pathway
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Accession:GO:0097190 term browser browse the term
Definition:The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Comment:This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Synonyms:exact_synonym: apoptotic signalling pathway;   induction of apoptosis by extracellular signals
 alt_id: GO:0008624


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apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of
involved_in
ISO
IEA
(MGI:1860411|PMID:10845921) MGI
Ensembl
PMID:10845921 GO_REF:0000107 MGI:1860411 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Anxa6 annexin A6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:3,978,047...4,029,485 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936492:14,818,561...14,902,231 JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2671672|PMID:12931191)
(MGI:2158953|PMID:11717309), (MGI:3057092|PMID:15231831)
MGI
Ensembl
PMID:11717309 PMID:12931191 PMID:15231831 GO_REF:0000107 MGI:2158953 MGI:2671672 MGI:3057092 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bak1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2676517|PMID:14507967), (MGI:2677915|PMID:12925707)
(MGI:3796786|PMID:18436203)
MGI
Ensembl
PMID:12925707 PMID:14507967 PMID:18436203 GO_REF:0000107 MGI:2676517 MGI:2677915 MGI:3796786 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bbc3 BCL2 binding component 3 involved_in ISO (PMID:11463392) UniProt PMID:11463392 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chrNW_004936520:5,707,542...5,716,966 JBrowse link
G Camk2b calcium/calmodulin dependent protein kinase II beta acts_upstream_of ISO (MGI:3710042|PMID:17367784) MGI PMID:17367784 MGI:3710042 NCBI chrNW_004936478:19,183,493...19,278,457 JBrowse link
G Casp10 caspase 10 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936726:460,556...489,550 JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450211|PMID:12477715), (MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:12477715 PMID:16183742 GO_REF:0000107 MGI:2450211 MGI:3603971 NCBI chrNW_004936527:739,325...754,259 JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936510:2,420,924...2,447,634 JBrowse link
G Cav1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chrNW_004936631:335,411...363,407 JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (MGI:80946|PMID:8666928) MGI PMID:8666928 MGI:80946 NCBI chrNW_004936542:3,379,361...3,390,677 JBrowse link
G Cd5 CD5 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chrNW_004936581:1,854,166...1,866,843 JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936507:10,077,345...10,264,705 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446)
(MGI:3051737|PMID:15131783)
MGI
Ensembl
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Dapk1 death associated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936680:2,842,930...3,020,757 JBrowse link
G Dapk3 death associated protein kinase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1196722|PMID:9488481)
(MGI:3687891|PMID:12917339)
MGI
Ensembl
PMID:9488481 PMID:12917339 GO_REF:0000107 MGI:1196722 MGI:3687891 NCBI chrNW_004936588:2,246,142...2,257,733 JBrowse link
G Daxx death domain associated protein acts_upstream_of_or_within ISO (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chrNW_004936476:25,546,091...25,550,390 JBrowse link
G Dido1 death inducer-obliterator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1340704|PMID:10393935) MGI
InterPro
Ensembl
PMID:10393935 GO_REF:0000002 GO_REF:0000107 MGI:1340704 NCBI chrNW_004936514:10,370,961...10,422,484 JBrowse link
G Fadd Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:4880811|PMID:21209208) MGI
Ensembl
PMID:21209208 GO_REF:0000107 MGI:4880811 NCBI chrNW_004936512:7,544,047...7,575,922 JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO (MGI:65483|PMID:7511063), (MGI:80946|PMID:8666928) RGD
MGI
PMID:7511063 PMID:8666928 PMID:16953119 MGI:65483 MGI:80946 RGD:1600313 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand involved_in
acts_upstream_of_or_within
ISO (PMID:11101870)
(MGI:3525895|PMID:15629131), (MGI:65483|PMID:7511063)
BHF-UCL
MGI
PMID:7511063 PMID:11101870 PMID:15629131 MGI:3525895 MGI:65483 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,496,301...2,569,019 JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:5287344|PMID:21750715) MGI
Ensembl
PMID:21750715 GO_REF:0000107 MGI:5287344 NCBI chrNW_004936677:2,721,451...2,730,398 JBrowse link
G Ing5 inhibitor of growth family member 5 acts_upstream_of
involved_in
ISO
IEA
(MGI:5287344|PMID:21750715) MGI
Ensembl
PMID:21750715 GO_REF:0000107 MGI:5287344 NCBI chrNW_004936745:261,371...271,447 JBrowse link
G Inhbb inhibin subunit beta B acts_upstream_of
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446) MGI
Ensembl
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chrNW_004936469:50,186,036...50,191,455 JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chrNW_004936543:8,460,526...8,508,524 JBrowse link
G LOC101962495 transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chrNW_004936570:457,993...460,735 JBrowse link
G LOC101968601 signal transducer CD24 acts_upstream_of_or_within ISO (MGI:2686748|PMID:14707049), (MGI:3757615|PMID:8920854), (MGI:3757616|PMID:8943715) MGI PMID:8920854 PMID:8943715 PMID:14707049 MGI:2686748 MGI:3757615 MGI:3757616 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chrNW_004936510:1,772,971...1,836,075 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of ISO (MGI:3619752|PMID:16458303) MGI PMID:16458303 MGI:3619752 NCBI chrNW_004936728:1,775,746...1,893,895 JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of
involved_in
ISO
IEA
(MGI:3619752|PMID:16458303) MGI
Ensembl
PMID:16458303 GO_REF:0000107 MGI:3619752 NCBI chrNW_004936739:551,678...602,027 JBrowse link
G Mllt11 MLLT11 transcription factor 7 cofactor involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936580:1,274,658...1,283,505 JBrowse link
G Moap1 modulator of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,111,256...1,113,651 JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:3796786|PMID:18436203) MGI
Ensembl
PMID:18436203 GO_REF:0000107 MGI:3796786 NCBI chrNW_004936659:2,590,291...2,593,482 JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:1,946,058...1,953,734 JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:3,062,279...3,077,493 JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO PMID:12857854 BHF-UCL PMID:12857854 RGD:8554350 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687891|PMID:12917339) MGI
Ensembl
PMID:12917339 GO_REF:0000107 MGI:3687891 NCBI chrNW_004936698:650,225...746,593 JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chrNW_004936490:14,139,125...14,150,377 JBrowse link
G Pde3a phosphodiesterase 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936548:5,758,634...6,072,195 JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3603971|PMID:16183742) Ensembl
MGI
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chrNW_004936888:565,889...571,273 JBrowse link
G Ppard peroxisome proliferator activated receptor delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:23,799,285...23,886,606 JBrowse link
G Psen1 presenilin 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3044464|PMID:15148382) MGI
Ensembl
PMID:15148382 GO_REF:0000107 MGI:3044464 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Psen2 presenilin 2 acts_upstream_of ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
G Ptgis prostaglandin I2 synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,775,884...4,814,574 JBrowse link
G Senp1 SUMO specific peptidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:5,932,594...5,989,819 JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:7,850,370...7,899,998 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:10,033,095...10,042,713 JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chrNW_004936501:12,773,967...12,776,642 JBrowse link
G Tfpt TCF3 fusion partner involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936994:234,978...239,425 JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chrNW_004936588:2,818,909...2,827,797 JBrowse link
G Tm2d1 TM2 domain containing 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2135414|PMID:11278849) MGI
Ensembl
PMID:11278849 GO_REF:0000107 MGI:2135414 NCBI chrNW_004936522:368,824...403,871 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3525895|PMID:15629131), (MGI:67096|PMID:8208546) MGI
Ensembl
PMID:8208546 PMID:15629131 GO_REF:0000107 MGI:3525895 MGI:67096 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936471:30,213,742...30,312,873 JBrowse link
G Umod uromodulin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6107740|PMID:28990932) MGI
Ensembl
PMID:28990932 GO_REF:0000107 MGI:6107740 NCBI chrNW_004936501:5,833,391...5,846,021 JBrowse link
G Vdr vitamin D receptor ISO RGD PMID:9579411 RGD:70308 NCBI chrNW_004936512:5,741,836...5,800,999 JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446) MGI
Ensembl
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3612236|PMID:16365167) MGI
Ensembl
PMID:16365167 GO_REF:0000107 MGI:3612236 NCBI chrNW_004936602:1,089,979...1,114,376 JBrowse link
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:9,407,578...9,449,611 JBrowse link
G Bad BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1343652|PMID:10476969) MGI
Ensembl
PMID:10476969 GO_REF:0000107 MGI:1343652 NCBI chrNW_004936807:708,340...750,127 JBrowse link
G Casp3 caspase 3 involved_in ISO (MGI:4355273|PMID:19626005) ComplexPortal PMID:19626005 MGI:4355273 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5521568|PMID:22089168)
(MGI:5486419|PMID:22675671)
(MGI:2386520|PMID:12065591), (MGI:3687663|PMID:10588860)
MGI
Ensembl
PMID:10588860 PMID:12065591 PMID:22089168 PMID:22675671 GO_REF:0000107 MGI:2386520 MGI:3687663 MGI:5486419 MGI:5521568 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Cd27 CD27 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936709:1,312,434...1,317,592 JBrowse link
G Cd70 CD70 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:3,918,944...3,921,720 JBrowse link
G Cttn cortactin acts_upstream_of
involved_in
ISO
IEA
(MGI:5437589|PMID:22660580) MGI
Ensembl
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chrNW_004936599:481,234...503,857 JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of ISO (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687663|PMID:10588860)
(MGI:3603971|PMID:16183742)
MGI
Ensembl
PMID:10588860 PMID:16183742 GO_REF:0000107 MGI:3603971 MGI:3687663 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within
ISO (PMID:22891283)
(MGI:3818355|PMID:17980593)
(MGI:2183141|PMID:12011074)
UniProt
MGI
PMID:12011074 PMID:17980593 PMID:22891283 MGI:2183141 MGI:3818355 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand involved_in ISO (PMID:22891283) UniProt PMID:22891283 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G G0s2 G0/G1 switch 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:3,428,157...3,429,176 JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936690:2,293,740...2,353,450 JBrowse link
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:16942485) BHF-UCL PMID:16942485 NCBI chrNW_004936519:6,166,060...6,180,652 JBrowse link
G Il33 interleukin 33 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5437589|PMID:22660580) MGI
Ensembl
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chrNW_004936539:763,755...791,461 JBrowse link
G Il7 interleukin 7 acts_upstream_of
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chrNW_004936702:110,625...162,957 JBrowse link
G Inhba inhibin subunit beta A involved_in ISO (PMID:9884026) BHF-UCL PMID:9884026 NCBI chrNW_004936478:16,878,725...16,884,065 JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5009182|PMID:12426001) MGI
Ensembl
PMID:12426001 GO_REF:0000107 MGI:5009182 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3711847|PMID:10747083) MGI
Ensembl
PMID:10747083 GO_REF:0000107 MGI:3711847 NCBI chrNW_004936512:10,290,706...10,294,647 JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3711847|PMID:10747083) MGI
Ensembl
PMID:10747083 GO_REF:0000107 MGI:3711847 NCBI chrNW_004936512:10,247,049...10,254,748 JBrowse link
G LOC101977665 tumor necrosis factor ligand superfamily member 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2667292|PMID:12821115) MGI
Ensembl
PMID:12821115 GO_REF:0000107 MGI:2667292 NCBI chrNW_004936595:831,252...839,783 JBrowse link
G Mllt11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chrNW_004936580:1,274,658...1,283,505 JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1930995|PMID:10924506) MGI
Ensembl
PMID:10924506 GO_REF:0000107 MGI:1930995 NCBI chrNW_004936596:1,946,058...1,953,734 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3700102|PMID:17286969) MGI
Ensembl
PMID:17286969 GO_REF:0000107 MGI:3700102 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Parp2 poly(ADP-ribose) polymerase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2386520|PMID:12065591) MGI
Ensembl
PMID:12065591 GO_REF:0000107 MGI:2386520 NCBI chrNW_004936877:554,969...564,905 JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:3578073|PMID:15858817) MGI
Ensembl
PMID:15858817 GO_REF:0000107 MGI:3578073 NCBI chrNW_004936471:6,809,181...6,834,189 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chrNW_004936888:565,889...571,273 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1306978|PMID:9806545) MGI
Ensembl
PMID:9806545 GO_REF:0000107 MGI:1306978 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of ISO (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of
involved_in
ISO
IEA
(MGI:80946|PMID:8666928) MGI
Ensembl
PMID:8666928 GO_REF:0000107 MGI:80946 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Rb1cc1 RB1 inducible coiled-coil 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3689241|PMID:17015619) MGI
Ensembl
PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chrNW_004936590:260,685...335,143 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943 JBrowse link
G Rnf41 ring finger protein 41 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:605,302...630,645 JBrowse link
G Sfrp1 secreted frizzled related protein 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3040721|PMID:14976225) MGI
Ensembl
PMID:14976225 GO_REF:0000107 MGI:3040721 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2386810|PMID:12235122) MGI
Ensembl
PMID:12235122 GO_REF:0000107 MGI:2386810 NCBI chrNW_004936495:7,500,991...7,528,520 JBrowse link
G Siva1 SIVA1 apoptosis inducing factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:641,456...650,067 JBrowse link
G Smad3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISS AgBase GO_REF:0000024 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISS
IEA
AgBase
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936628:310,720...394,002 JBrowse link
G Tlr3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5510543|PMID:19498109)
(MGI:5521568|PMID:22089168)
MGI
Ensembl
PMID:19498109 PMID:22089168 GO_REF:0000107 MGI:5510543 MGI:5521568 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A acts_upstream_of_or_within ISO (MGI:2667292|PMID:12821115) MGI PMID:12821115 MGI:2667292 NCBI chrNW_004936694:1,149,169...1,151,098 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:69721|PMID:7990930) MGI
Ensembl
PMID:7990930 GO_REF:0000107 MGI:69721 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Tradd TNFRSF1A associated via death domain acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5521568|PMID:22089168) MGI
Ensembl
PMID:22089168 GO_REF:0000107 MGI:5521568 NCBI chrNW_004936475:17,628,297...17,634,919 JBrowse link
G Wwox WW domain containing oxidoreductase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3851310|PMID:19366691) MGI
Ensembl
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chrNW_004936475:26,342,245...27,209,563 JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of
involved_in
ISO
IEA
(MGI:3818355|PMID:17980593) MGI
Ensembl
PMID:17980593 GO_REF:0000107 MGI:3818355 NCBI chrNW_004936551:5,638,383...5,740,523 JBrowse link
G Znf274 zinc finger protein 274 acts_upstream_of_or_within ISO (MGI:1929440|PMID:10545116) MGI PMID:10545116 MGI:1929440 NCBI chrNW_004936897:657,094...672,964 JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2183839|PMID:12115603), (MGI:2675215|PMID:12944463)
(MGI:3029504|PMID:12431371)
(MGI:3032484|PMID:14967141)
MGI
Ensembl
PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 GO_REF:0000107 MGI:2183839 MGI:2675215 MGI:3029504 MGI:3032484 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3513163|PMID:11527400) MGI
Ensembl
PMID:11527400 GO_REF:0000107 MGI:3513163 NCBI chrNW_004936486:8,985,871...9,007,461 JBrowse link
G Bak1 BCL2 antagonist/killer 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3575206|PMID:15680329)
(MGI:3581932|PMID:15967824)
MGI
Ensembl
PMID:15680329 PMID:15967824 GO_REF:0000107 MGI:3575206 MGI:3581932 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581932|PMID:15967824)
(MGI:3575206|PMID:15680329)
MGI
Ensembl
PMID:15680329 PMID:15967824 GO_REF:0000107 MGI:3575206 MGI:3581932 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2179928|PMID:12082633) MGI
Ensembl
PMID:12082633 GO_REF:0000107 MGI:2179928 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bcl2l1 BCL2 like 1 acts_upstream_of_or_within ISO (MGI:2183839|PMID:12115603) MGI PMID:12115603 MGI:2183839 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Bcl2l10 BCL2 like 10 acts_upstream_of ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chrNW_004936471:13,943,600...13,946,085 JBrowse link
G Bcl2l11 BCL2 like 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581932|PMID:15967824) MGI
Ensembl
PMID:15967824 GO_REF:0000107 MGI:3581932 NCBI chrNW_004936783:15,493...50,959 JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3691999|PMID:11536012) MGI
Ensembl
PMID:11536012 GO_REF:0000107 MGI:3691999 NCBI chrNW_004936527:739,325...754,259 JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of
involved_in
ISO
IEA
(MGI:1097047|PMID:9299161) MGI
Ensembl
PMID:9299161 GO_REF:0000107 MGI:1097047 NCBI chrNW_004936512:5,861,933...5,894,898 JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:5315030|PMID:22411810) MGI
Ensembl
PMID:22411810 GO_REF:0000107 MGI:5315030 NCBI chrNW_004936531:7,865,907...8,036,020 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI
Ensembl
PMID:18322241 PMID:18971423 GO_REF:0000107 MGI:3777228 MGI:3833195 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:497,783...515,247 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3577160|PMID:15817220) MGI
Ensembl
PMID:15817220 GO_REF:0000107 MGI:3577160 NCBI chrNW_004936648:395,526...546,705 JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2158099|PMID:11700312) MGI
Ensembl
PMID:11700312 GO_REF:0000107 MGI:2158099 NCBI chrNW_004936514:6,223,745...6,401,985 JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2675560|PMID:13679421) MGI
Ensembl
PMID:13679421 GO_REF:0000107 MGI:2675560 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO (MGI:2675560|PMID:13679421) MGI PMID:13679421 MGI:2675560 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of
involved_in
ISO
IEA
(MGI:3690587|PMID:16956603) MGI
Ensembl
PMID:16956603 GO_REF:0000107 MGI:3690587 NCBI chrNW_004936480:18,114,231...18,195,884 JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3029504|PMID:12431371) MGI
Ensembl
PMID:12431371 GO_REF:0000107 MGI:3029504 NCBI chrNW_004936564:4,788,036...4,907,600 JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3691999|PMID:11536012) MGI
Ensembl
PMID:11536012 GO_REF:0000107 MGI:3691999 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2179928|PMID:12082633) MGI
Ensembl
PMID:12082633 GO_REF:0000107 MGI:2179928 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:2387238|PMID:12124386), (MGI:2675215|PMID:12944463), (MGI:3032484|PMID:14967141), (MGI:3057092|PMID:15231831), (MGI:3513163|PMID:11527400), (MGI:3575206|PMID:15680329) MGI PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 More... MGI:2387238 MGI:2675215 MGI:3032484 MGI:3057092 MGI:3513163 MGI:3575206 NCBI chrNW_004936647:3,102,922...3,104,758 JBrowse link
G Itgav integrin subunit alpha V involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936506:10,750,116...10,839,018 JBrowse link
G Itm2b integral membrane protein 2B acts_upstream_of_or_within ISO (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chrNW_004936565:1,535,570...1,557,667 JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038547|PMID:15039234) MGI
Ensembl
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chrNW_004936507:5,566,144...5,650,412 JBrowse link
G Lcn2 lipocalin 2 acts_upstream_of_or_within ISO (MGI:4821076|PMID:16377569) MGI PMID:16377569 MGI:4821076 NCBI chrNW_004936487:15,721,752...15,725,396 JBrowse link
G LOC101973872 bcl-2-like protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:1,039,970...1,044,942 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:803,452...806,966 JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chrNW_004936474:27,568,325...27,611,315 JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3793518|PMID:17903173) MGI
Ensembl
PMID:17903173 GO_REF:0000107 MGI:3793518 NCBI chrNW_004936588:1,176,861...1,188,931 JBrowse link
G Moap1 modulator of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,111,256...1,113,651 JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3038547|PMID:15039234) MGI
Ensembl
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chrNW_004936538:3,394,623...3,596,025 JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within ISO (MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:2681362 NCBI chrNW_004936627:635,784...641,290 JBrowse link
G Tgfb2 transforming growth factor beta 2 acts_upstream_of ISO (MGI:67124|PMID:8206089) MGI PMID:8206089 MGI:67124 NCBI chrNW_004936628:310,720...394,002 JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3029504|PMID:12431371) MGI
Ensembl
PMID:12431371 GO_REF:0000107 MGI:3029504 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10597216) MGI
Ensembl
PMID:10597216 GO_REF:0000107 NCBI chrNW_004936486:8,985,871...9,007,461 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1349210|PMID:10597216) MGI
Ensembl
PMID:10597216 GO_REF:0000107 MGI:1349210 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10597216) MGI
Ensembl
PMID:10597216 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bex3 brain expressed X-linked 3 acts_upstream_of_or_within ISO (MGI:1859527|PMID:10764727) MGI PMID:10764727 MGI:1859527 NCBI chrNW_004936547:7,842,016...7,843,087 JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in ISO (PMID:18188704) UniProt PMID:18188704 NCBI chrNW_004939661:2,128...6,384 JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
ISO (PMID:11717445)
(MGI:3054336|PMID:15322156)
ComplexPortal
MGI
PMID:11717445 PMID:15322156 MGI:3054336 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Casp8ap2 caspase 8 associated protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1347587|PMID:10235259) MGI
Ensembl
PMID:10235259 GO_REF:0000107 MGI:1347587 NCBI chrNW_004936510:2,420,924...2,447,634 JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051747|PMID:15010850)
(MGI:4431305|PMID:20053891)
MGI
Ensembl
PMID:15010850 PMID:20053891 GO_REF:0000107 MGI:3051747 MGI:4431305 NCBI chrNW_004936680:2,842,930...3,020,757 JBrowse link
G Daxx death domain associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,546,091...25,550,390 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Ddx47 DEAD-box helicase 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936587:4,482,883...4,496,429 JBrowse link
G Dedd death effector domain containing acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1306907|PMID:9774341) MGI
Ensembl
PMID:9774341 GO_REF:0000107 MGI:1306907 NCBI chrNW_004936903:436,949...448,670 JBrowse link
G Dedd2 death effector domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:285,874...302,910 JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936504:12,247,584...12,259,962 JBrowse link
G Fadd Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within
involved_in
ISO (MGI:2687085|PMID:12801066), (MGI:3038547|PMID:15039234), (MGI:3576402|PMID:15632112), (MGI:3687663|PMID:10588860), (MGI:3819026|PMID:18363966), (MGI:77677|PMID:8524870)
(MGI:3029504|PMID:12431371)
(MGI:2687085|PMID:12801066), (MGI:3029504|PMID:12431371), (MGI:77677|PMID:8524870)
(MGI:1340173|PMID:10429671)
(MGI:5009197|PMID:10950869)
MGI
BHF-UCL
PMID:8524870 PMID:10429671 PMID:10588860 PMID:10950869 PMID:12431371 More... MGI:1340173 MGI:2687085 MGI:3029504 MGI:3038547 MGI:3576402 MGI:3687663 MGI:3819026 MGI:5009197 MGI:77677 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand acts_upstream_of_or_within
involved_in
ISO (PMID:26582200)
(PMID:18835034)
(MGI:3038547|PMID:15039234), (MGI:3687663|PMID:10588860)
RGD
MGI
BHF-UCL
PMID:10588860 PMID:15039234 PMID:16689665 PMID:18835034 PMID:26582200 MGI:3038547 MGI:3687663 RGD:1582444 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:3831045|PMID:19139395) MGI
Ensembl
PMID:19139395 GO_REF:0000107 MGI:3831045 NCBI chrNW_004936516:4,536,664...4,539,331 JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:11131641)
(PMID:11429161)
UniProt PMID:11131641 PMID:11429161 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G LOC101961849 inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of
involved_in
ISO
IEA
(MGI:4431305|PMID:20053891) MGI
Ensembl
PMID:20053891 GO_REF:0000107 MGI:4431305 NCBI chrNW_004936600:1,874,696...1,898,033 JBrowse link
G LOC101962367 DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:10,056,809...10,243,021 JBrowse link
G LOC101969316 GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:534,042...536,289 JBrowse link
G Moap1 modulator of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,111,256...1,113,651 JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038547|PMID:15039234) MGI
Ensembl
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chrNW_004936538:3,394,623...3,596,025 JBrowse link
G Ngf nerve growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936627:635,784...641,290 JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chrNW_004936888:565,889...571,273 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038547|PMID:15039234) MGI
Ensembl
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of
involved_in
ISO
IEA
(MGI:3612236|PMID:16365167) MGI
Ensembl
PMID:16365167 GO_REF:0000107 MGI:3612236 NCBI chrNW_004936602:1,089,979...1,114,376 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Skil SKI like proto-oncogene acts_upstream_of
involved_in
ISO
IEA
(MGI:1858539|PMID:10811619) MGI
Ensembl
PMID:10811619 GO_REF:0000107 MGI:1858539 NCBI chrNW_004936593:2,109,414...2,132,871 JBrowse link
G Sort1 sortilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936704:832,651...901,658 JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:4420852|PMID:20080598) MGI
Ensembl
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chrNW_004936470:44,159,449...44,436,295 JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of
involved_in
ISO
IEA
(MGI:4420852|PMID:20080598) MGI
Ensembl
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chrNW_004936514:7,686,760...7,784,948 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3029504|PMID:12431371)
(MGI:4420852|PMID:20080598)
MGI
Ensembl
PMID:12431371 PMID:20080598 GO_REF:0000107 MGI:3029504 MGI:4420852 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube4b ubiquitination factor E4B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:3,934,439...4,051,083 JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO RGD PMID:11790788 RGD:1358682 NCBI chrNW_004936496:7,759,656...7,761,555 JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of_or_within ISO (MGI:3047056|PMID:15187231) MGI PMID:15187231 MGI:3047056 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Mettl21c methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5781029|PMID:24677265) MGI
Ensembl
PMID:24677265 GO_REF:0000107 MGI:5781029 NCBI chrNW_004936472:8,355,075...8,366,229 JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of
involved_in
ISO
IEA
(MGI:3692043|PMID:14502238) MGI
Ensembl
PMID:14502238 GO_REF:0000107 MGI:3692043 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2l10 BCL2 like 10 acts_upstream_of ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chrNW_004936471:13,943,600...13,946,085 JBrowse link
G Bnip3 BCL2 interacting protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3696331|PMID:16954213) MGI
Ensembl
PMID:16954213 GO_REF:0000107 MGI:3696331 NCBI chrNW_004936486:18,449,371...18,460,435 JBrowse link
G Clu clusterin involved_in ISO (PMID:21567405) UniProt PMID:21567405 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Flcn folliculin acts_upstream_of
involved_in
ISO
IEA
(MGI:5050037|PMID:21258407) MGI
Ensembl
PMID:21258407 GO_REF:0000107 MGI:5050037 NCBI chrNW_004936741:881,150...901,296 JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3696331|PMID:16954213) MGI
Ensembl
PMID:16954213 GO_REF:0000107 MGI:3696331 NCBI chrNW_004936888:375,372...378,125 JBrowse link
G Htra2 HtrA serine peptidase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3511636|PMID:15509788) MGI
Ensembl
PMID:15509788 GO_REF:0000107 MGI:3511636 NCBI chrNW_004936556:741,718...746,016 JBrowse link
G Klc1 kinesin light chain 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936621:1,471,574...1,505,119 JBrowse link
G LOC101961404 influenza virus NS1A binding protein acts_upstream_of
involved_in
ISO
IEA
(MGI:4819697|PMID:15485691) MGI
Ensembl
PMID:15485691 GO_REF:0000107 MGI:4819697 NCBI chrNW_004936481:4,915,516...4,935,130 JBrowse link
G Mllt11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chrNW_004936580:1,274,658...1,283,505 JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677657|PMID:14632208) MGI
Ensembl
PMID:14632208 GO_REF:0000107 MGI:2677657 NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Nbn nibrin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3805397|PMID:18614044) MGI
Ensembl
PMID:18614044 GO_REF:0000107 MGI:3805397 NCBI chrNW_004936544:3,773,828...3,812,673 JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO (MGI:5315351|PMID:15863367) UniProt PMID:15863367 MGI:5315351 NCBI chrNW_004936519:8,759,702...8,790,823 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711) UniProt PMID:14500711 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:1,786,223...1,816,083 JBrowse link
G Prkca protein kinase C alpha acts_upstream_of_or_within ISO (MGI:2671671|PMID:12928424) MGI PMID:12928424 MGI:2671671 NCBI chrNW_004936541:6,231,604...6,488,201 JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1932564|PMID:10859351) MGI
Ensembl
PMID:10859351 GO_REF:0000107 MGI:1932564 NCBI chrNW_004936495:7,500,991...7,528,520 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23313858) AgBase PMID:23313858 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Siva1 SIVA1 apoptosis inducing factor involved_in
NOT|involved_in
ISO (PMID:12011449) BHF-UCL PMID:12011449 NCBI chrNW_004936621:641,456...650,067 JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1344924|PMID:10479688) MGI
Ensembl
PMID:10479688 GO_REF:0000107 MGI:1344924 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:344,837...350,950 JBrowse link
G Casp6 caspase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936563:912,502...920,025 JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of ISO (MGI:5662131|PMID:26158450) MGI PMID:26158450 MGI:5662131 NCBI chrNW_004936529:7,577,122...7,632,161 JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:5,005,211...5,013,439 JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1927703|PMID:11095619) MGI
Ensembl
PMID:11095619 GO_REF:0000107 MGI:1927703 NCBI chrNW_004936561:6,894,827...6,901,058 JBrowse link
G E2f2 E2F transcription factor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1927703|PMID:11095619) MGI
Ensembl
PMID:11095619 GO_REF:0000107 MGI:1927703 NCBI chrNW_004936474:8,719,243...8,739,811 JBrowse link
G Eda2r ectodysplasin A2 receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4454200|PMID:20434500) MGI
Ensembl
PMID:20434500 GO_REF:0000107 MGI:4454200 NCBI chrNW_004936635:1,303,855...1,335,766 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:397,140...1,424,805 JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 involved_in ISO (PMID:16835243) UniProt PMID:16835243 NCBI chrNW_004936647:3,843,544...3,849,428 JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor acts_upstream_of_or_within ISO (MGI:1891484|PMID:10518217) MGI PMID:10518217 MGI:1891484 NCBI chrNW_004936549:7,074,644...7,163,531 JBrowse link
G LOC101969970 p53 apoptosis effector related to PMP22 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1929912|PMID:10733530) MGI
Ensembl
PMID:10733530 GO_REF:0000107 MGI:1929912 NCBI chrNW_004936560:5,285,071...5,301,253 JBrowse link
G Mybbp1a MYB binding protein 1a involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:1,095,022...1,108,545 JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:11,534,412...11,549,128 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)
UniProt PMID:14500851 PMID:15102863 MGI:2679929 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3034149|PMID:14992722) MGI
Ensembl
PMID:14992722 GO_REF:0000107 MGI:3034149 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:2,857,017...2,859,705 JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chrNW_004936535:2,705,184...2,711,785 JBrowse link
G Ppp1r13b protein phosphatase 1 regulatory subunit 13B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:1,383,137...1,447,376 JBrowse link
G Pycard PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:13,550,702...13,552,774 JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of
involved_in
ISO
IEA
(MGI:3583493|PMID:15989966) MGI
Ensembl
PMID:15989966 GO_REF:0000107 MGI:3583493 NCBI chrNW_004936501:2,893,304...2,926,795 JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936842:656,508...661,894 JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (MGI:2183272|PMID:12135983) MGI PMID:12135983 MGI:2183272 NCBI chrNW_004936529:266,671...292,103 JBrowse link
G Stk11 serine/threonine kinase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2183272|PMID:12135983), (MGI:3589512|PMID:16107883)
(MGI:4454200|PMID:20434500)
MGI
Ensembl
PMID:12135983 PMID:16107883 PMID:20434500 GO_REF:0000107 MGI:2183272 MGI:3589512 MGI:4454200 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Tp53bp2 tumor protein p53 binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936526:936,981...1,000,070 JBrowse link
G Wwox WW domain containing oxidoreductase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1930321|PMID:11058590) MGI
Ensembl
PMID:11058590 GO_REF:0000107 MGI:1930321 NCBI chrNW_004936475:26,342,245...27,209,563 JBrowse link
G Znf385b zinc finger protein 385B involved_in ISO (PMID:22945289) UniProt PMID:22945289 NCBI chrNW_004936509:8,470,696...8,744,880 JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Atm ATM serine/threonine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1926715|PMID:11040211), (MGI:3652689|PMID:16777961)
(MGI:3714678|PMID:17476307)
MGI
Ensembl
PMID:11040211 PMID:16777961 PMID:17476307 GO_REF:0000107 MGI:1926715 MGI:3652689 MGI:3714678 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3057092|PMID:15231831)
(MGI:3029504|PMID:12431371)
MGI
Ensembl
PMID:12431371 PMID:15231831 GO_REF:0000107 MGI:3029504 MGI:3057092 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bak1 BCL2 antagonist/killer 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
MGI
Ensembl
PMID:15901672 PMID:15967824 GO_REF:0000107 MGI:3581932 MGI:3689797 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2675761|PMID:12952892)
(MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
MGI
Ensembl
PMID:12952892 PMID:15901672 PMID:15967824 GO_REF:0000107 MGI:2675761 MGI:3581932 MGI:3689797 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3584078|PMID:15983387) MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bcl2l1 BCL2 like 1 acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Bcl2l11 BCL2 like 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11546872)
(MGI:3581932|PMID:15967824)
MGI
Ensembl
PMID:11546872 PMID:15967824 GO_REF:0000107 MGI:3581932 NCBI chrNW_004936783:15,493...50,959 JBrowse link
G Brca1 BRCA1 DNA repair associated acts_upstream_of_or_within ISO (PMID:14654789) MGI PMID:14654789 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:3714678|PMID:17476307) MGI PMID:17476307 MGI:3714678 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:15657060) UniProt PMID:15657060 NCBI chrNW_004936474:3,178,097...3,196,130 JBrowse link
G Chek2 checkpoint kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Crip1 cysteine rich protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:101,046...102,660 JBrowse link
G E2f1 E2F transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:6,894,827...6,901,058 JBrowse link
G Ei24 EI24 autophagy associated transmembrane protein acts_upstream_of_or_within ISO (MGI:1350723|PMID:10594026) MGI PMID:10594026 MGI:1350723 NCBI chrNW_004936743:1,957,948...1,970,885 JBrowse link
G Epha2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:3,648,395...3,673,856 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1913261|PMID:11005836) MGI
Ensembl
PMID:11005836 GO_REF:0000107 MGI:1913261 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Fnip2 folliculin interacting protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chrNW_004936576:5,221,619...5,335,133 JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936538:8,122,557...8,126,157 JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:11854317 RGD:625692 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:741,718...746,016 JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3775338|PMID:11753682) MGI
Ensembl
PMID:11753682 GO_REF:0000107 MGI:3775338 NCBI chrNW_004936837:401,475...402,769 JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:20188669) UniProt PMID:20188669 NCBI chrNW_004936557:6,066,207...6,090,767 JBrowse link
G Mael maelstrom spermatogenic transposon silencer acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3813746|PMID:18694567) MGI
Ensembl
PMID:18694567 GO_REF:0000107 MGI:3813746 NCBI chrNW_004936481:18,903,153...18,928,195 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3689797|PMID:15901672) MGI
Ensembl
PMID:15901672 GO_REF:0000107 MGI:3689797 NCBI chrNW_004936580:803,452...806,966 JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2678630|PMID:14562041) MGI
Ensembl
PMID:14562041 GO_REF:0000107 MGI:2678630 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Moap1 modulator of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,111,256...1,113,651 JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1334080|PMID:10097137)
(MGI:3029112|PMID:14744764)
MGI
Ensembl
PMID:10097137 PMID:14744764 GO_REF:0000107 MGI:1334080 MGI:3029112 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3053495|PMID:15324697) MGI
Ensembl
PMID:15324697 GO_REF:0000107 MGI:3053495 NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chrNW_004936470:20,480,844...20,485,955 JBrowse link
G Nfatc4 nuclear factor of activated T cells 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709926|PMID:17242187) MGI
Ensembl
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chrNW_004936722:178,866...187,847 JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chrNW_004936529:3,304,171...3,308,422 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709926|PMID:17242187) MGI
Ensembl
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1306978|PMID:9806545)
(MGI:3580934|PMID:15626733)
MGI
Ensembl
PMID:9806545 PMID:15626733 GO_REF:0000107 MGI:1306978 MGI:3580934 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1334987|PMID:10197627) MGI
Ensembl
PMID:10197627 GO_REF:0000107 MGI:1334987 NCBI chrNW_004936785:324,655...350,496 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450507|PMID:12604618) MGI
Ensembl
PMID:12604618 GO_REF:0000107 MGI:2450507 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of
involved_in
ISO
IEA
(MGI:3584078|PMID:15983387) MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936599:2,348,869...2,353,907 JBrowse link
G Sfn stratifin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:11,274,927...11,279,427 JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Skil SKI like proto-oncogene acts_upstream_of
involved_in
ISO
IEA
(MGI:1858539|PMID:10811619) MGI
Ensembl
PMID:10811619 GO_REF:0000107 MGI:1858539 NCBI chrNW_004936593:2,109,414...2,132,871 JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3691744|PMID:15642323) MGI
Ensembl
PMID:15642323 GO_REF:0000107 MGI:3691744 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709926|PMID:17242187) MGI
Ensembl
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709926|PMID:17242187) MGI
Ensembl
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709926|PMID:17242187) MGI
Ensembl
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:1,219,101...1,229,937 JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chrNW_004936471:30,213,742...30,312,873 JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of
involved_in
ISO
IEA
(MGI:4839431|PMID:19966869) MGI
Ensembl
PMID:19966869 GO_REF:0000107 MGI:4839431 NCBI chrNW_004936528:6,483,898...6,596,136 JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO (MGI:1913261|PMID:11005836) MGI PMID:11005836 MGI:1913261 NCBI chrNW_004936524:6,467,365...6,493,556 JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease involved_in ISO (PMID:18264133) UniProt PMID:18264133 NCBI chrNW_004936483:14,601,671...14,611,613 JBrowse link
G Atad5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Bag6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,866,235...1,885,266 JBrowse link
G Bbc3 BCL2 binding component 3 acts_upstream_of_or_within ISO (MGI:3603103|PMID:16151013) MGI PMID:16151013 MGI:3603103 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16384933) MGI
Ensembl
PMID:16384933 GO_REF:0000107 NCBI chrNW_004936706:1,410,848...1,427,822 JBrowse link
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:3714678|PMID:17476307)
(MGI:3579926|PMID:15735671)
MGI PMID:15735671 PMID:17476307 MGI:3579926 MGI:3714678 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Cdip1 cell death inducing p53 target 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17599062) MGI
Ensembl
PMID:17599062 GO_REF:0000107 NCBI chrNW_004936530:4,559,062...4,578,896 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2675761|PMID:12952892) MGI
Ensembl
PMID:12952892 GO_REF:0000107 MGI:2675761 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1354114|PMID:10710310) MGI
Ensembl
PMID:10710310 GO_REF:0000107 MGI:1354114 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Ddit4 DNA damage inducible transcript 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:6,646,864...6,648,982 JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:5,542,873...5,555,469 JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:5438719|PMID:22768269) MGI
Ensembl
PMID:22768269 GO_REF:0000107 MGI:5438719 NCBI chrNW_004936471:6,835,410...6,838,582 JBrowse link
G Ep300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3619785|PMID:16537918) MGI
Ensembl
PMID:16537918 GO_REF:0000107 MGI:3619785 NCBI chrNW_004936690:2,293,740...2,353,450 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3619785|PMID:16537918) MGI
Ensembl
PMID:16537918 GO_REF:0000107 MGI:3619785 NCBI chrNW_004936592:3,800,619...3,934,347 JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1334080|PMID:10097137) MGI
Ensembl
PMID:10097137 GO_REF:0000107 MGI:1334080 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3784021|PMID:11896600) MGI
Ensembl
PMID:11896600 GO_REF:0000107 MGI:3784021 NCBI chrNW_004936501:11,998,064...11,999,431 JBrowse link
G Phlda3 pleckstrin homology like domain family A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936567:2,981,632...2,984,906 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:1858284|PMID:10807576) MGI PMID:10807576 MGI:1858284 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Pml PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Ppp2r5c protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chrNW_004936835:54,478...192,486 JBrowse link
G Pycard PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:13,550,702...13,552,774 JBrowse link
G Rps27l ribosomal protein S27 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:23,738,896...23,742,355 JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (MGI:2183272|PMID:12135983) MGI PMID:12135983 MGI:2183272 NCBI chrNW_004936529:266,671...292,103 JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Snw1 SNW domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:6,494,556...6,531,297 JBrowse link
G Tmem109 transmembrane protein 109 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4437179|PMID:20060811) MGI
Ensembl
PMID:20060811 GO_REF:0000107 MGI:4437179 NCBI chrNW_004936581:2,009,357...2,019,381 JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3578084|PMID:15735665) MGI
Ensembl
PMID:15735665 GO_REF:0000107 MGI:3578084 NCBI chrNW_004936524:1,219,101...1,229,937 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2675761|PMID:12952892)
(MGI:3584078|PMID:15983387)
(PMID:14654789), (PMID:14744935)
(MGI:2183272|PMID:12135983)
(MGI:3690827|PMID:16286009)
(MGI:3714678|PMID:17476307)
(MGI:3652689|PMID:16777961)
MGI
Ensembl
PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... GO_REF:0000107 MGI:2183272 MGI:2675761 MGI:3584078 MGI:3652689 MGI:3690827 MGI:3714678 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3693137|PMID:17122775) MGI
Ensembl
PMID:17122775 GO_REF:0000107 MGI:3693137 NCBI chrNW_004936578:492,267...705,282 JBrowse link
G Tp73 tumor protein p73 involved_in
acts_upstream_of
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936737:171,894...211,464 JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO (PMID:16901786) UniProt PMID:16901786 NCBI chrNW_004936612:742,777...804,919 JBrowse link
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor mitochondria associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:1,441,508...1,477,133 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:14,818,561...14,902,231 JBrowse link
G Atf4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,818,301...11,836,221 JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:552,066...585,093 JBrowse link
G Bag6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,866,235...1,885,266 JBrowse link
G Bak1 BCL2 antagonist/killer 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2667259|PMID:12847083)
(MGI:3575207|PMID:15776018)
MGI
Ensembl
PMID:12847083 PMID:15776018 GO_REF:0000107 MGI:2667259 MGI:3575207 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3575207|PMID:15776018)
(MGI:2667259|PMID:12847083)
MGI
Ensembl
PMID:12847083 PMID:15776018 GO_REF:0000107 MGI:2667259 MGI:3575207 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bbc3 BCL2 binding component 3 involved_in ISO (PMID:16407291)
(MGI:4879048|PMID:21159964), (MGI:5448480|PMID:22761832), (MGI:5621265|PMID:16407291)
ParkinsonsUK-UCL
UniProt
PMID:16407291 PMID:21159964 PMID:22761832 MGI:4879048 MGI:5448480 MGI:5621265 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15776018) MGI
Ensembl
PMID:15776018 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936816:307,736...335,953 JBrowse link
G Chac1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:4,344,234...4,346,998 JBrowse link
G Ddit3 DNA damage inducible transcript 3 involved_in
acts_upstream_of_or_within
ISO (PMID:15322075)
(MGI:2158984|PMID:11854325)
(MGI:5496937|PMID:23624402)
(MGI:1335331|PMID:9531536), (MGI:4879048|PMID:21159964)
(PMID:18940792), (PMID:20829347)
UniProt
MGI
ParkinsonsUK-UCL
PMID:9531536 PMID:11854325 PMID:15322075 PMID:18940792 PMID:20829347 More... MGI:1335331 MGI:2158984 MGI:4879048 MGI:5496937 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:11,334,859...11,383,668 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (MGI:2136067|PMID:11430819) MGI PMID:11430819 MGI:2136067 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1929557|PMID:11146108) MGI
Ensembl
PMID:11146108 GO_REF:0000107 MGI:1929557 NCBI chrNW_004936541:4,613,197...4,705,911 JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1346198|PMID:9755171) MGI
Ensembl
PMID:9755171 GO_REF:0000107 MGI:1346198 NCBI chrNW_004936501:8,332,507...8,350,176 JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:2,154,517...2,199,913 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5619738|PMID:23028846) CACAO PMID:23028846 MGI:5619738 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Ins insulin acts_upstream_of_or_within ISO (MGI:2158984|PMID:11854325) MGI PMID:11854325 MGI:2158984 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936577:3,896,455...4,198,396 JBrowse link
G LOC101962367 DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:10,056,809...10,243,021 JBrowse link
G LOC101966403 speckle type BTB/POZ protein acts_upstream_of ISO (MGI:4836774|PMID:20811152) MGI PMID:20811152 MGI:4836774 NCBI chrNW_004936490:11,894,449...11,969,730 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:3,988,696...4,197,953 JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4836774|PMID:20811152) MGI
Ensembl
PMID:20811152 GO_REF:0000107 MGI:4836774 NCBI chrNW_004936472:23,102,534...23,107,127 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:5621265 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4849347|PMID:21030605) MGI
Ensembl
PMID:21030605 GO_REF:0000107 MGI:4849347 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Qrich1 glutamine rich 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:753,842...802,405 JBrowse link
G Rnf186 ring finger protein 186 involved_in ISO (PMID:23896122) UniProt PMID:23896122 NCBI chrNW_004936474:5,947,077...5,947,772 JBrowse link
G Selenok selenoprotein K involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:4,546,186...4,552,764 JBrowse link
G Syvn1 synoviolin 1 acts_upstream_of ISO (MGI:3575050|PMID:15611074) MGI PMID:15611074 MGI:3575050 NCBI chrNW_004936599:4,235,779...4,243,395 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3050914|PMID:15304216) MGI
Ensembl
PMID:15304216 GO_REF:0000107 MGI:3050914 NCBI chrNW_004936512:7,427,926...7,448,700 JBrowse link
G Tmem117 transmembrane protein 117 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:2,327,765...2,765,488 JBrowse link
G Tp53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:18,077,850...18,082,817 JBrowse link
G Ube2k ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within ISO PMID:18710920 MGI PMID:18710920 RGD:8554156 NCBI chrNW_004936482:7,244,972...7,323,263 JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:3840374 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd10 programmed cell death 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936593:4,650,624...4,693,387 JBrowse link
G Stk25 serine/threonine kinase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:420,591...426,890 JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:4,729,984...4,826,367 JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:18,449,371...18,460,435 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4867601|PMID:20935145) MGI
Ensembl
PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chrNW_004936595:919,807...935,367 JBrowse link
intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA damage inducible transcript 3 involved_in ISO (MGI:5784990|PMID:14752510) ParkinsonsUK-UCL PMID:14752510 MGI:5784990 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
CAFA PMID:21716255 MGI:5474549 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2179539|PMID:10827969) MGI
Ensembl
PMID:10827969 GO_REF:0000107 MGI:2179539 NCBI chrNW_004936469:13,872,701...14,019,170 JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of
involved_in
ISO
IEA
(MGI:3654719|PMID:16571598) MGI
Ensembl
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chrNW_004936604:548,844...551,031 JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chrNW_004936558:4,362,693...4,387,705 JBrowse link
G Arl6ip5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936603:1,524,959...1,549,923 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2679141|PMID:12855558) MGI
Ensembl
PMID:12855558 GO_REF:0000107 MGI:2679141 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Diablo diablo IAP-binding mitochondrial protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3587135|PMID:16085184) MGI
Ensembl
PMID:16085184 GO_REF:0000107 MGI:3587135 NCBI chrNW_004936558:2,260,459...2,268,941 JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2153292|PMID:11562367), (MGI:3613414|PMID:15663476)
(MGI:3698597|PMID:16373599)
MGI
Ensembl
PMID:11562367 PMID:15663476 PMID:16373599 GO_REF:0000107 MGI:2153292 MGI:3613414 MGI:3698597 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:15659221 RGD:1641883 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G LOC101958593 GSK3B interacting protein involved_in ISO (PMID:25920809) UniProt PMID:25920809 NCBI chrNW_004936604:657,602...675,702 JBrowse link
G LOC101970101 cytochrome P450 1B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936663:345,021...355,188 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829088|PMID:18948261) MGI
Ensembl
PMID:18948261 GO_REF:0000107 MGI:3829088 NCBI chrNW_004936560:3,988,696...4,197,953 JBrowse link
G Mapt microtubule associated protein tau ISO RGD PMID:12420308 RGD:8158111 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Melk maternal embryonic leucine zipper kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829088|PMID:18948261) MGI
Ensembl
PMID:18948261 GO_REF:0000107 MGI:3829088 NCBI chrNW_004936524:4,479,639...4,544,561 JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4881403|PMID:19661248) MGI
Ensembl
PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chrNW_004936584:6,023,960...6,040,041 JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:2,597,593...2,633,780 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4849347|PMID:21030605) MGI
Ensembl
PMID:21030605 GO_REF:0000107 MGI:4849347 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) MGI PMID:10082581 MGI:1333612 NCBI chrNW_004936540:3,484,422...3,491,162 JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3691744|PMID:15642323) MGI
Ensembl
PMID:15642323 GO_REF:0000107 MGI:3691744 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO (PMID:19604147) UniProt PMID:19604147 NCBI chrNW_004936472:11,788,439...11,888,703 JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chrNW_004936471:30,213,742...30,312,873 JBrowse link
G Znf622 zinc finger protein 622 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:19,092,959...19,108,418 JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5566519|PMID:20436477) MGI
Ensembl
PMID:20436477 GO_REF:0000107 MGI:5566519 NCBI chrNW_004936807:708,340...750,127 JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in ISO (PMID:18188704) UniProt PMID:18188704 NCBI chrNW_004939661:2,128...6,384 JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:18,449,371...18,460,435 JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2158099|PMID:11700312) MGI
Ensembl
PMID:11700312 GO_REF:0000107 MGI:2158099 NCBI chrNW_004936514:6,223,745...6,401,985 JBrowse link
G Rhot1 ras homolog family member T1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:2,658,225...2,725,889 JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISO (PMID:12482879) UniProt PMID:12482879 NCBI chrNW_004936501:336,506...341,671 JBrowse link
G Rtl10 retrotransposon Gag like 10 involved_in ISO (PMID:23055042) UniProt PMID:23055042 NCBI chrNW_004936619:3,755,537...3,760,909 JBrowse link
G Vdac2 voltage dependent anion channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:4,122,447...4,136,228 JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4359364|PMID:17488777) MGI
Ensembl
PMID:17488777 GO_REF:0000107 MGI:4359364 NCBI chrNW_004936490:1,209,760...1,320,046 JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936735:2,004,373...2,092,501 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3796786|PMID:18436203) MGI
Ensembl
PMID:18436203 GO_REF:0000107 MGI:3796786 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2158578|PMID:11546872) MGI
Ensembl
PMID:11546872 GO_REF:0000107 MGI:2158578 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bdnf brain derived neurotrophic factor involved_in ISO (MGI:6295053|PMID:26708520) ARUK-UCL PMID:26708520 MGI:6295053 NCBI chrNW_004936540:5,530,081...5,582,765 JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) MGI PMID:11546872 MGI:2158578 NCBI chrNW_004936471:3,573,437...3,594,438 JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chrNW_004936520:5,707,542...5,716,966 JBrowse link
G Cth cystathionine gamma-lyase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5304595|PMID:22244329) MGI
Ensembl
PMID:22244329 GO_REF:0000107 MGI:5304595 NCBI chrNW_004936591:1,619,446...1,643,667 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446)
(MGI:3051737|PMID:15131783)
MGI
Ensembl
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4880811|PMID:21209208) MGI
Ensembl
PMID:21209208 GO_REF:0000107 MGI:4880811 NCBI chrNW_004936512:7,544,047...7,575,922 JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) BHF-UCL PMID:25590961 MGI:5780531 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:25633408 RGD:13507311 NCBI chrNW_004936529:1,779,582...1,801,251 JBrowse link
G Gnai3 G protein subunit alpha i3 ISO RGD PMID:25633408 RGD:13507311 NCBI chrNW_004936704:1,031,476...1,075,662 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581090|PMID:15731106) MGI
Ensembl
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chrNW_004936543:2,110,351...2,111,896 JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3688933|PMID:16857185) MGI PMID:16857185 MGI:3688933 NCBI chrNW_004936472:25,855,873...25,879,062 JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3056248|PMID:15499020) Ensembl
MGI
PMID:15499020 GO_REF:0000107 MGI:3056248 NCBI chrNW_004936762:1,292,572...1,319,145 JBrowse link
G Ing2 inhibitor of growth family member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4867787|PMID:21124965) MGI
Ensembl
PMID:21124965 GO_REF:0000107 MGI:4867787 NCBI chrNW_004936554:5,585,953...5,593,536 JBrowse link
G LOC101973967 cyclin-dependent kinase 11B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:1,609,676...1,628,861 JBrowse link
G Madd MAP kinase activating death domain acts_upstream_of_or_within ISO (MGI:3700423|PMID:14735464) MGI PMID:14735464 MGI:3700423 NCBI chrNW_004936562:1,891,120...1,936,559 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chrNW_004936510:1,772,971...1,836,075 JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936629:201,269...211,058 JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) ARUK-UCL PMID:25487955 NCBI chrNW_004936501:12,664,861...12,668,819 JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4848231|PMID:21059917) MGI
Ensembl
PMID:21059917 GO_REF:0000107 MGI:4848231 NCBI chrNW_004936664:1,095,815...1,105,751 JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2675510|PMID:12970171) MGI
Ensembl
PMID:12970171 GO_REF:0000107 MGI:2675510 NCBI chrNW_004936538:8,439,548...8,456,021 JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO (MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:2183867 NCBI chrNW_004936492:1,234,025...1,384,838 JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3796786|PMID:18436203) MGI
Ensembl
PMID:18436203 GO_REF:0000107 MGI:3796786 NCBI chrNW_004936659:2,590,291...2,593,482 JBrowse link
G Nog noggin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3640733|PMID:16712836) MGI
Ensembl
PMID:16712836 GO_REF:0000107 MGI:3640733 NCBI chrNW_004936490:6,262,651...6,264,069 JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:21,912,118...21,920,486 JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (MGI:4837988|PMID:20719856) MGI PMID:20719856 MGI:4837988 NCBI chrNW_004936694:153,958...161,635 JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chrNW_004936490:14,139,125...14,150,377 JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3044464|PMID:15148382) MGI
Ensembl
PMID:15148382 GO_REF:0000107 MGI:3044464 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:802,753...810,270 JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:7,427,926...7,448,700 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31124343) ARUK-UCL
Ensembl
PMID:31124343 GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446) MGI
Ensembl
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936611:2,710,512...2,761,484 JBrowse link
G Il9 interleukin 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4367548|PMID:18551134) MGI
Ensembl
PMID:18551134 GO_REF:0000107 MGI:4367548 NCBI chrNW_004936597:2,983,953...2,986,975 JBrowse link
G Il9r interleukin 9 receptor acts_upstream_of_or_within ISO (MGI:4367548|PMID:18551134) MGI PMID:18551134 MGI:4367548 NCBI chrNW_004936501:829,236...840,130 JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Nle1 notchless homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5468737|PMID:23231322) MGI
Ensembl
PMID:23231322 GO_REF:0000107 MGI:5468737 NCBI chrNW_004936538:101,245...109,796 JBrowse link
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,321,278...3,326,720 JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004936706:840,968...855,552 JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in ISO PMID:15383280
PMID:12191471
UniProt PMID:12191471 PMID:15383280 RGD:10047289 RGD:631884 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 BCL2 like 1 involved_in ISO (PMID:29507230) UniProt PMID:29507230 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:3,727,104...3,730,962 JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 involved_in ISO PMID:15665855
(MGI:5616321|PMID:15665855)
ParkinsonsUK-UCL PMID:15665855 MGI:5616321 RGD:1558627 NCBI chrNW_004936562:2,739,908...2,772,484 JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO (MGI:5525071|PMID:22240901) MGI PMID:22240901 MGI:5525071 NCBI chrNW_004936470:8,180,468...8,183,694 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,091,115...9,102,101 JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) ParkinsonsUK-UCL PMID:23453807 MGI:5495588 NCBI chrNW_004936809:1,280,254...1,306,964 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 involved_in ISO (PMID:12150907), (PMID:20625543) ParkinsonsUK-UCL PMID:12150907 PMID:20625543 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 involved_in ISO (PMID:12150907), (PMID:20625543) ParkinsonsUK-UCL PMID:12150907 PMID:20625543 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936711:1,027,531...1,113,796 JBrowse link
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4836774|PMID:20811152) MGI
Ensembl
PMID:20811152 GO_REF:0000107 MGI:4836774 NCBI chrNW_004936472:23,102,534...23,107,127 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chrNW_004936514:4,065,455...4,083,847 JBrowse link
G Selenos selenoprotein S involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:2,589,773...2,600,837 JBrowse link
G Syvn1 synoviolin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3575050|PMID:15611074) MGI
Ensembl
PMID:15611074 GO_REF:0000107 MGI:3575050 NCBI chrNW_004936599:4,235,779...4,243,395 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5525071|PMID:22240901) MGI
Ensembl
PMID:22240901 GO_REF:0000107 MGI:5525071 NCBI chrNW_004936512:7,427,926...7,448,700 JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18628206) MGI
Ensembl
PMID:18628206 GO_REF:0000107 NCBI chrNW_004936522:8,877,832...8,900,659 JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:18,339,915...18,364,973 JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:4,005,616...4,018,135 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:20,743,195...20,811,567 JBrowse link
G Ar androgen receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936635:485,903...647,820 JBrowse link
G Birc6 baculoviral IAP repeat containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:903,295...1,115,434 JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5486419|PMID:22675671) Ensembl
MGI
PMID:22675671 GO_REF:0000107 MGI:5486419 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Cttn cortactin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5437589|PMID:22660580) MGI
Ensembl
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chrNW_004936599:481,234...503,857 JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
G Fcmr Fc fragment of IgM receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:3576402 NCBI chrNW_004936557:5,707,138...5,718,192 JBrowse link
G Gclc glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3047441|PMID:15288121) MGI
Ensembl
PMID:15288121 GO_REF:0000107 MGI:3047441 NCBI chrNW_004936476:7,371,270...7,418,756 JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Igf1 insulin like growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5491082|PMID:23468852) MGI
Ensembl
PMID:23468852 GO_REF:0000107 MGI:5491082 NCBI chrNW_004936557:5,765,093...5,769,853 JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chrNW_004936702:110,625...162,957 JBrowse link
G Itga6 integrin subunit alpha 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:2,508,446...2,587,643 JBrowse link
G Itgav integrin subunit alpha V involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936506:10,750,116...10,839,018 JBrowse link
G Lgals3 galectin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:20,861...38,568 JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4879057|PMID:21151901) MGI
Ensembl
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chrNW_004936580:5,374,208...5,395,442 JBrowse link
G LOC101966195 huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
G LOC101977655 glutamate--cysteine ligase regulatory subunit acts_upstream_of_or_within ISO (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chrNW_004936537:5,356,914...5,378,998 JBrowse link
G LOC101978201 pleckstrin homology domain interacting protein acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17636024) MGI
Ensembl
PMID:17636024 GO_REF:0000107 NCBI chrNW_004936510:11,076,790...11,198,483 JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Nrp1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936574:1,694,433...1,834,720 JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2673247|PMID:12897128) MGI
Ensembl
PMID:12897128 GO_REF:0000107 MGI:2673247 NCBI chrNW_004936485:9,825,425...9,932,162 JBrowse link
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5546581|PMID:23950925)
(PMID:24113711)
MGI
Ensembl
PMID:23950925 PMID:24113711 GO_REF:0000107 MGI:5546581 NCBI chrNW_004936599:3,099,256...3,110,566 JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
G Psme3 proteasome activator subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,542,933...17,549,347 JBrowse link
G Rb1cc1 RB1 inducible coiled-coil 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3689241|PMID:17015619) MGI
Ensembl
PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chrNW_004936590:260,685...335,143 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5304595|PMID:22244329) MGI
Ensembl
PMID:22244329 GO_REF:0000107 MGI:5304595 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5521568|PMID:22089168) MGI
Ensembl
PMID:22089168 GO_REF:0000107 MGI:5521568 NCBI chrNW_004936534:9,326,307...9,361,943 JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4456959|PMID:11493700) MGI
Ensembl
PMID:11493700 GO_REF:0000107 MGI:4456959 NCBI chrNW_004936490:3,441,046...3,492,917 JBrowse link
G Scg2 secretogranin II involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:5,367,270...5,372,627 JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (MGI:3609513|PMID:16226406) MGI PMID:16226406 MGI:3609513 NCBI chrNW_004936735:1,702,754...1,984,141 JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936516:1,267,128...1,429,040 JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936758:1,115,980...1,132,225 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chrNW_004936486:3,473,877...3,660,565 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:7,656,523...7,680,043 JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) BHF-UCL PMID:11567634 MGI:2150820 NCBI chrNW_004936737:1,901,749...1,904,382 JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096) BHF-UCL PMID:21828096 MGI:5287519 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3818355|PMID:17980593) MGI
Ensembl
PMID:17980593 GO_REF:0000107 MGI:3818355 NCBI chrNW_004936551:5,638,383...5,740,523 JBrowse link
G Zmynd11 zinc finger MYND-type containing 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:13,779,266...13,872,042 JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chrNW_004936646:1,865,154...1,881,614 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:8358790) MGI
Ensembl
PMID:8358790 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bcl2l10 BCL2 like 10 acts_upstream_of_or_within ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chrNW_004936471:13,943,600...13,946,085 JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1097047|PMID:9299161) MGI
Ensembl
PMID:9299161 GO_REF:0000107 MGI:1097047 NCBI chrNW_004936512:5,861,933...5,894,898 JBrowse link
G Csf2 colony stimulating factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:3,081,896...3,083,864 JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5315030|PMID:22411810) MGI
Ensembl
PMID:22411810 GO_REF:0000107 MGI:5315030 NCBI chrNW_004936531:7,865,907...8,036,020 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI
Ensembl
PMID:18322241 PMID:18971423 GO_REF:0000107 MGI:3777228 MGI:3833195 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 acts_upstream_of_or_within ISO (MGI:3833195|PMID:18971423) MGI PMID:18971423 MGI:3833195 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3577160|PMID:15817220) MGI
Ensembl
PMID:15817220 GO_REF:0000107 MGI:3577160 NCBI chrNW_004936648:395,526...546,705 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3690587|PMID:16956603) MGI
Ensembl
PMID:16956603 GO_REF:0000107 MGI:3690587 NCBI chrNW_004936480:18,114,231...18,195,884 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Gata1 GATA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:742,862...750,843 JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:4,291,391...4,310,752 JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3610244|PMID:16086688) MGI
Ensembl
PMID:16086688 GO_REF:0000107 MGI:3610244 NCBI chrNW_004936476:5,759,739...5,817,766 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) BHF-UCL PMID:10748004 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:84869|PMID:8950980) MGI
Ensembl
PMID:8950980 GO_REF:0000107 MGI:84869 NCBI chrNW_004936702:110,625...162,957 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 involved_in ISO (PMID:17167422) BHF-UCL PMID:17167422 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 involved_in ISO (PMID:17167422) BHF-UCL PMID:17167422 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 involved_in ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chrNW_004936471:27,491,255...27,728,572 JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936881:372,713...377,655 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:803,452...806,966 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (MGI:86755|PMID:9115640) MGI PMID:9115640 MGI:86755 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943 JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2178763|PMID:11050396) MGI
Ensembl
PMID:11050396 GO_REF:0000107 MGI:2178763 NCBI chrNW_004936496:7,196,936...7,287,367 JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5142392|PMID:10518215) MGI
Ensembl
PMID:10518215 GO_REF:0000107 MGI:5142392 NCBI chrNW_004936590:3,813,916...3,817,642 JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2656105|PMID:12574163) MGI
Ensembl
PMID:12574163 GO_REF:0000107 MGI:2656105 NCBI chrNW_004936726:709,037...728,696 JBrowse link
G Tert telomerase reverse transcriptase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936815:468,987...492,666 JBrowse link
G Tnf tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:7,472,788...7,547,408 JBrowse link
G Zc3hc1 zinc finger C3HC-type containing 1 acts_upstream_of_or_within ISO (MGI:2670822|PMID:12748172) MGI PMID:12748172 MGI:2670822 NCBI chrNW_004936579:5,163,771...5,189,130 JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chrNW_004936580:5,213,323...5,230,861 JBrowse link
G Bcl2l1 BCL2 like 1 acts_upstream_of_or_within ISO (PMID:26582200) MGI PMID:26582200 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:23415688) BHF-UCL PMID:23415688 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (MGI:2450205|PMID:12466268) MGI PMID:12466268 MGI:2450205 NCBI chrNW_004936588:3,395,859...3,398,215 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26582200) MGI
Ensembl
PMID:26582200 GO_REF:0000107 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO (MGI:2152512|PMID:11485996) MGI PMID:11485996 MGI:2152512 NCBI chrNW_004936680:2,842,930...3,020,757 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Faim Fas apoptotic inhibitory molecule acts_upstream_of_or_within ISO (MGI:1332875|PMID:10075978) MGI PMID:10075978 MGI:1332875 NCBI chrNW_004936540:843,463...863,029 JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26582200) MGI
Ensembl
PMID:26582200 GO_REF:0000107 NCBI chrNW_004936512:7,544,047...7,575,922 JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:10903502) BHF-UCL PMID:10903502 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936576:1,306,076...1,313,485 JBrowse link
G Fgg fibrinogen gamma chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936576:1,343,657...1,352,085 JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3054501|PMID:15314156) MGI
Ensembl
PMID:15314156 GO_REF:0000107 MGI:3054501 NCBI chrNW_004936734:354,798...428,356 JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3831045|PMID:19139395) MGI
Ensembl
PMID:19139395 GO_REF:0000107 MGI:3831045 NCBI chrNW_004936516:4,536,664...4,539,331 JBrowse link
G Hmox1 heme oxygenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G LOC101961849 inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4431305|PMID:20053891) MGI
Ensembl
PMID:20053891 GO_REF:0000107 MGI:4431305 NCBI chrNW_004936600:1,874,696...1,898,033 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO PMID:12191471
PMID:15383280
UniProt PMID:12191471 PMID:15383280 RGD:10047289 RGD:631884 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687663|PMID:10588860) MGI
Ensembl
PMID:10588860 GO_REF:0000107 MGI:3687663 NCBI chrNW_004936740:416,355...426,801 JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:1099227|PMID:9353287) MGI PMID:9353287 MGI:1099227 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3612236|PMID:16365167) MGI
Ensembl
PMID:16365167 GO_REF:0000107 MGI:3612236 NCBI chrNW_004936602:1,089,979...1,114,376 JBrowse link
G Rffl ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:139,690...203,600 JBrowse link
G Rnf34 ring finger protein 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:2,901,386...2,918,976 JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936576:604,174...612,440 JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:803,154...820,000 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:5,124,955...5,138,988 JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:3,115,357...3,130,289 JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:4,005,616...4,018,135 JBrowse link
G Kdm6a lysine demethylase 6A ISO RGD PMID:30887465 RGD:151665136 NCBI chrNW_004936502:10,980,303...11,196,711 JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chrNW_004936471:26,589,251...26,628,302 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936540:907,118...1,041,814 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:7,427,926...7,448,700 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bcl2l1 BCL2 like 1 involved_in ISO (PMID:12011449), (PMID:21567405) BHF-UCL PMID:12011449 PMID:21567405 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Bcl2l10 BCL2 like 10 acts_upstream_of_or_within ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chrNW_004936471:13,943,600...13,946,085 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Fignl1 fidgetin like 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4944122|PMID:20886204) MGI
Ensembl
PMID:20886204 GO_REF:0000107 MGI:4944122 NCBI chrNW_004936686:1,412,544...1,415,939 JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (MGI:3807157|PMID:18511420) MGI PMID:18511420 MGI:3807157 NCBI chrNW_004936494:5,352,126...5,409,648 JBrowse link
G Gcg glucagon involved_in ISO (MGI:4453294|PMID:19915011) UniProt PMID:19915011 MGI:4453294 NCBI chrNW_004936469:16,906,658...16,916,045 JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4889029|PMID:21093383) MGI
Ensembl
PMID:21093383 GO_REF:0000107 MGI:4889029 NCBI chrNW_004936474:15,320,635...15,351,418 JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO (MGI:4889029|PMID:21093383) MGI PMID:21093383 MGI:4889029 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2178571|PMID:11325543) MGI
Ensembl
PMID:11325543 GO_REF:0000107 MGI:2178571 NCBI chrNW_004936601:626,354...662,477 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,091,115...9,102,101 JBrowse link
G LOC101961404 influenza virus NS1A binding protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4819697|PMID:15485691) MGI
Ensembl
PMID:15485691 GO_REF:0000107 MGI:4819697 NCBI chrNW_004936481:4,915,516...4,935,130 JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1332866|PMID:10098834) MGI
Ensembl
PMID:10098834 GO_REF:0000107 MGI:1332866 NCBI chrNW_004936562:3,113,217...3,122,794 JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:1,946,058...1,953,734 JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,667,780...1,674,670 JBrowse link
G Noc2l NOC2 like nucleolar associated transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:2,087,123...2,098,153 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO PMID:15383280 UniProt PMID:15383280 RGD:10047289 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936711:1,027,531...1,113,796 JBrowse link
G Parl presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,945,765...5,992,972 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004936706:840,968...855,552 JBrowse link
G Ppif peptidylprolyl isomerase F involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:404,574...411,381 JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO (PMID:26124677) UniProt PMID:26124677 NCBI chrNW_004936614:923,977...995,343 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Uri1 URI1 prefoldin like chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:5,379,253...5,419,595 JBrowse link
G Vdac2 voltage dependent anion channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:4,122,447...4,136,228 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in ISO (PMID:17904127) UniProt PMID:17904127 NCBI chrNW_004936479:20,297,385...20,315,263 JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO (MGI:5662131|PMID:26158450) MGI PMID:26158450 MGI:5662131 NCBI chrNW_004936529:7,577,122...7,632,161 JBrowse link
G LOC101964515 PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) MGI PMID:24506068 NCBI chrNW_004936778:1,350,647...1,379,497 JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) CAFA PMID:17310983 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (MGI:2182884|PMID:12101245) UniProt PMID:12101245 MGI:2182884 NCBI chrNW_004936567:268,151...299,494 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2670318|PMID:12858174) MGI
Ensembl
PMID:12858174 GO_REF:0000107 MGI:2670318 NCBI chrNW_004936470:41,354,387...41,401,308 JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3583493|PMID:15989966) MGI
Ensembl
PMID:15989966 GO_REF:0000107 MGI:3583493 NCBI chrNW_004936501:2,893,304...2,926,795 JBrowse link
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) UniProt PMID:24523556 MGI:5553386 NCBI chrNW_004936732:2,066,848...2,097,947 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO (PMID:20388803) BHF-UCL PMID:20388803 NCBI chrNW_004936525:1,559,575...1,570,679 JBrowse link
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3584078|PMID:15983387) MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Bcl2l1 BCL2 like 1 involved_in ISO (PMID:16608847) BHF-UCL PMID:16608847 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5662300|PMID:26219591) MGI
Ensembl
PMID:26219591 GO_REF:0000107 MGI:5662300 NCBI chrNW_004936807:708,340...750,127 JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936555:6,341,455...6,356,677 JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) BHF-UCL PMID:15750620 NCBI chrNW_004936659:840,602...843,078 JBrowse link
G Clu clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936617:4,224,131...4,239,080 JBrowse link
G Ddias DNA damage induced apoptosis suppressor involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936498:11,115,055...11,127,215 JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in ISO (PMID:14561758) BHF-UCL PMID:14561758 NCBI chrNW_004936576:604,174...612,440 JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,456,498...4,462,436 JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936590:3,813,916...3,817,642 JBrowse link
G Tmem161a transmembrane protein 161A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,274,989...2,287,288 JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) MGI PMID:11598139 NCBI chrNW_004936791:1,439,997...1,443,959 JBrowse link
G Trim32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:5,606,690...5,619,856 JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4839431|PMID:19966869) MGI
Ensembl
PMID:19966869 GO_REF:0000107 MGI:4839431 NCBI chrNW_004936528:6,483,898...6,596,136 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Bcl2l12 BCL2 like 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4834958|PMID:20837658) MGI
Ensembl
PMID:20837658 GO_REF:0000107 MGI:4834958 NCBI chrNW_004936664:3,482,562...3,488,663 JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)
BHF-UCL PMID:17045821 MGI:3690285 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Cd74 CD74 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936504:4,522,576...4,532,289 JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5438719|PMID:22768269) MGI
Ensembl
PMID:22768269 GO_REF:0000107 MGI:5438719 NCBI chrNW_004936471:6,835,410...6,838,582 JBrowse link
G Kdm1a lysine demethylase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:8,262,913...8,319,089 JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:18,966,239...19,016,829 JBrowse link
G Mif macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chrNW_004936580:4,691,870...4,694,092 JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936668:500,815...503,158 JBrowse link
G Znf385a zinc finger protein 385A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:11,562,635...11,585,026 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) MGI PMID:18681888 MGI:3822965 NCBI chrNW_004936472:25,855,873...25,879,062 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
G Trap1 TNF receptor associated protein 1 involved_in ISO PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chrNW_004936694:667,687...704,994 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chrNW_004936580:5,213,323...5,230,861 JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3654719|PMID:16571598) MGI
Ensembl
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chrNW_004936604:548,844...551,031 JBrowse link
G Epo erythropoietin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:742,722...745,332 JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) CAFA PMID:21716255 NCBI chrNW_004936697:2,440,943...2,453,897 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
CAFA PMID:21716255 MGI:5474549 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3654719|PMID:16571598) Ensembl
MGI
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chrNW_004936604:548,844...551,031 JBrowse link