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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptotic signaling pathway
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Accession:GO:0097190 term browser browse the term
Definition:The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Comment:This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Synonyms:exact_synonym: apoptotic signalling pathway;   induction of apoptosis by extracellular signals
 alt_id: GO:0008624



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apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor acts_upstream_of
involved_in
ISO
IEA
(MGI:1860411|PMID:10845921) MGI
Ensembl
PMID:10845921 GO_REF:0000107 MGI:1860411 NCBI chr14:49,467,186...49,485,845
Ensembl chr14:49,468,877...49,485,850
JBrowse link
G ANXA6 annexin A6 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr16:71,857,229...71,913,723
Ensembl chr16:71,857,258...71,913,723
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2671672|PMID:12931191)
(MGI:2158953|PMID:11717309), (MGI:3057092|PMID:15231831)
MGI
Ensembl
PMID:11717309 PMID:12931191 PMID:15231831 GO_REF:0000107 MGI:2158953 MGI:2671672 MGI:3057092 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:15901672) UniProt PMID:15901672 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2676517|PMID:14507967), (MGI:2677915|PMID:12925707)
(MGI:3796786|PMID:18436203)
MGI
Ensembl
PMID:12925707 PMID:14507967 PMID:18436203 GO_REF:0000107 MGI:2676517 MGI:2677915 MGI:3796786 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BBC3 BCL2 binding component 3 involved_in ISO (PMID:11463392) UniProt PMID:11463392 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chr10:52,586,089...52,596,154
Ensembl chr10:52,586,509...52,596,564
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta acts_upstream_of ISO (MGI:3710042|PMID:17367784) MGI PMID:17367784 MGI:3710042 NCBI chr18:50,862,225...50,956,263
Ensembl chr18:50,861,466...50,956,225
JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase involved_in IEA GOC
GOC
GO_REF:0000108 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
JBrowse link
G CASP10 caspase 10 involved_in IEA GOC
GOC
GO_REF:0000108 NCBI chr15:104,858,082...104,895,941
Ensembl chr15:104,858,100...104,894,933
JBrowse link
G CASP2 caspase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450211|PMID:12477715), (MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:12477715 PMID:16183742 GO_REF:0000107 MGI:2450211 MGI:3603971 NCBI chr18:6,946,432...6,966,088
Ensembl chr18:6,941,937...6,966,061
JBrowse link
G CASP3 caspase 3 involved_in IEA GOC
GOC
GO_REF:0000108 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CASP8AP2 caspase 8 associated protein 2 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 1:57,834,251...57,864,837
Ensembl chr 1:57,835,145...57,862,473
JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1340173|PMID:10429671) Ensembl
Ensembl
MGI
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,203...107,162,935
JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:80946|PMID:8666928) MGI
Ensembl
PMID:8666928 GO_REF:0000107 MGI:80946 NCBI chr 9:45,619,730...45,633,972
Ensembl chr 9:45,619,482...45,633,968
JBrowse link
G CD5 CD5 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1340173|PMID:10429671) Ensembl
Ensembl
MGI
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chr 2:10,648,973...10,673,479
Ensembl chr 2:10,648,974...10,673,919
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in IEA GOC
GOC
GO_REF:0000108 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,616...104,835,630
JBrowse link
G CLCN1 chloride voltage-gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,902,540...6,941,530
Ensembl chr18:6,902,542...6,940,449
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:89,257,603...89,480,414
Ensembl chr 5:89,267,944...89,479,712
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446)
(MGI:3051737|PMID:15131783)
MGI
Ensembl
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G DAP death associated protein involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr16:250,212...322,075
Ensembl chr16:250,217...321,929
JBrowse link
G DAPK1 death associated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350
JBrowse link
G DAPK3 death associated protein kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3687891|PMID:12917339)
(MGI:1196722|PMID:9488481)
Ensembl
MGI
Ensembl
PMID:9488481 PMID:12917339 GO_REF:0000107 MGI:1196722 MGI:3687891 NCBI chr 2:74,758,962...74,776,355
Ensembl chr 2:74,759,004...74,775,330
JBrowse link
G DAPL1 death associated protein like 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr15:65,796,462...65,820,450
Ensembl chr15:65,796,462...65,820,448
JBrowse link
G DAXX death domain associated protein acts_upstream_of_or_within ISO (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110
JBrowse link
G DIDO1 death inducer-obliterator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1340704|PMID:10393935) InterPro
InterPro
MGI
Ensembl
PMID:10393935 GO_REF:0000002 GO_REF:0000107 MGI:1340704 NCBI chr17:62,126,026...62,174,095
Ensembl chr17:62,125,122...62,174,071
JBrowse link
G FADD Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:4880811|PMID:21209208) MGI
Ensembl
PMID:21209208 GO_REF:0000107 MGI:4880811 NCBI chr 5:15,779,329...15,813,029
Ensembl chr 5:15,779,334...15,812,543
JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (MGI:65483|PMID:7511063), (MGI:80946|PMID:8666928) RGD
MGI
PMID:7511063 PMID:8666928 PMID:16953119 MGI:65483 MGI:80946 RGD:1600313 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FASLG Fas ligand acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3525895|PMID:15629131), (MGI:65483|PMID:7511063) MGI
Ensembl
PMID:7511063 PMID:15629131 GO_REF:0000107 MGI:3525895 MGI:65483 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,416,418...10,578,374
Ensembl chr 3:10,416,475...10,578,366
JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:5287344|PMID:21750715) MGI
Ensembl
PMID:21750715 GO_REF:0000107 MGI:5287344 NCBI chr12:51,923,764...51,931,875
Ensembl chr12:51,924,902...51,931,873
JBrowse link
G ING5 inhibitor of growth family member 5 acts_upstream_of
involved_in
ISO
IEA
(MGI:5287344|PMID:21750715) MGI
Ensembl
PMID:21750715 GO_REF:0000107 MGI:5287344 NCBI chr15:140,264,708...140,279,020
Ensembl chr15:140,264,766...140,279,010
JBrowse link
G INHBB inhibin subunit beta B acts_upstream_of
involved_in
ISO
IEA
(MGI:4454604|PMID:20454446) MGI
Ensembl
PMID:20454446 GO_REF:0000107 MGI:4454604 NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405
JBrowse link
G ISG12(A) putative ISG12(a) protein involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 7:115,356,619...115,361,537
Ensembl chr 7:115,356,517...115,361,538
JBrowse link
G LOC100519934 uncharacterized LOC100519934 acts_upstream_of_or_within ISO (MGI:2686748|PMID:14707049), (MGI:3757615|PMID:8920854), (MGI:3757616|PMID:8943715) MGI PMID:8920854 PMID:8943715 PMID:14707049 MGI:2686748 MGI:3757615 MGI:3757616 NCBI chr 1:73,119,758...73,124,368 JBrowse link
G LOC100522887 caspase-13 involved_in IEA GOC
GOC
GO_REF:0000108 NCBI chr 9:35,167,567...35,185,791 JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 acts_upstream_of ISO (MGI:3619752|PMID:16458303) MGI PMID:16458303 MGI:3619752 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 acts_upstream_of
involved_in
ISO
IEA
(MGI:3619752|PMID:16458303) MGI
Ensembl
PMID:16458303 GO_REF:0000107 MGI:3619752 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:98,165,990...98,171,674
Ensembl chr 4:98,164,676...98,171,674
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:11060313) BHF-UCL PMID:11060313 NCBI chr 7:114,571,624...114,574,052 JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:10924506) UniProt PMID:10924506 NCBI chr 2:58,401,542...58,410,414
Ensembl chr 2:58,401,551...58,411,981
JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:31,368,542...31,387,960
Ensembl chr14:31,368,303...31,387,905
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in ISO PMID:12857854 BHF-UCL PMID:12857854 RGD:8554350 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472
JBrowse link
G PAWR pro-apoptotic WT1 regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3687891|PMID:12917339) Ensembl
Ensembl
MGI
PMID:12917339 GO_REF:0000107 MGI:3687891 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,693,246...101,797,838
JBrowse link
G PCGF2 polycomb group ring finger 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:1932296|PMID:11290297) MGI
Ensembl
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chr12:23,362,631...23,375,779
Ensembl chr12:23,362,654...23,375,775
JBrowse link
G PDE3A phosphodiesterase 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:52,413,503...52,737,771
Ensembl chr 5:52,409,882...52,738,406
JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3603971|PMID:16183742) Ensembl
MGI
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr 2:499,294...505,740
Ensembl chr 2:499,303...504,871
JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:31,222,533...31,295,221
Ensembl chr 7:31,222,585...31,295,211
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3044464|PMID:15148382) MGI
Ensembl
PMID:15148382 GO_REF:0000107 MGI:3044464 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251
JBrowse link
G PTGIS prostaglandin I2 synthase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:51,153,151...51,200,515
Ensembl chr17:51,153,154...51,200,300
JBrowse link
G SENP1 SUMO specific peptidase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:78,419,849...78,476,315
Ensembl chr 5:78,423,383...78,476,195
JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:73,696,902...73,781,830
Ensembl chr14:73,724,100...73,781,800
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484
JBrowse link
G SOCS2 suppressor of cytokine signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:89,581,081...89,587,424
Ensembl chr 5:89,581,090...89,584,581
JBrowse link
G SPN sialophorin acts_upstream_of_or_within ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 3:17,978,731...17,982,222 JBrowse link
G TFPT TCF3 fusion partner involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:56,011,496...56,018,166
Ensembl chr 6:56,011,491...56,018,169
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2670551|PMID:12872135) Ensembl
Ensembl
MGI
PMID:12872135 GO_REF:0000107 MGI:2670551 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873
JBrowse link
G TM2D1 TM2 domain containing 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2135414|PMID:11278849)
GO_Central
Ensembl
GO_Central
MGI
PMID:11278849 PMID:21873635 GO_REF:0000107 MGI:2135414 NCBI chr 6:150,615,311...150,654,931
Ensembl chr 6:150,615,350...150,654,742
JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3525895|PMID:15629131), (MGI:67096|PMID:8208546) MGI
Ensembl
PMID:8208546 PMID:15629131 GO_REF:0000107 MGI:3525895 MGI:67096 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,201...45,312,539
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 1:168,353,655...168,453,175
Ensembl chr 1:168,350,557...168,453,344
JBrowse link
G UMOD uromodulin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6107740|PMID:28990932) Ensembl
Ensembl
MGI
PMID:28990932 GO_REF:0000107 MGI:6107740 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278
JBrowse link
G VDR vitamin D receptor ISO RGD PMID:9579411 RGD:70308 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475
JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of ISO (MGI:4454604|PMID:20454446) MGI PMID:20454446 MGI:4454604 NCBI chr 6:80,110,238...80,138,165 JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3612236|PMID:16365167) Ensembl
Ensembl
MGI
PMID:16365167 GO_REF:0000107 MGI:3612236 NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829
JBrowse link
G RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 involved_in IEA Ensembl GO_REF:0000107
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:17,314,322...17,350,726
Ensembl chr 5:17,314,276...17,350,722
JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BID BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1343652|PMID:10476969) Ensembl
Ensembl
MGI
PMID:10476969 GO_REF:0000107 MGI:1343652 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853
JBrowse link
G CASP3 caspase 3 involved_in ISO (MGI:4355273|PMID:19626005) ComplexPortal PMID:19626005 MGI:4355273 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2386520|PMID:12065591), (MGI:3687663|PMID:10588860)
(MGI:5486419|PMID:22675671)
(MGI:5521568|PMID:22089168)
MGI
Ensembl
PMID:10588860 PMID:12065591 PMID:22089168 PMID:22675671 GO_REF:0000107 MGI:2386520 MGI:3687663 MGI:5486419 MGI:5521568 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CD27 CD27 molecule involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:64,197,594...64,202,236
Ensembl chr 5:64,196,994...64,202,613
JBrowse link
G CD70 CD70 molecule involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:72,528,988...72,531,950
Ensembl chr 2:72,528,400...72,532,951
JBrowse link
G CTTN cortactin acts_upstream_of
involved_in
ISO
IEA
(MGI:5437589|PMID:22660580) MGI
Ensembl
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813
JBrowse link
G DAB2 DAB adaptor protein 2 acts_upstream_of ISO (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122
JBrowse link
G FADD Fas associated via death domain acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687663|PMID:10588860)
(MGI:3603971|PMID:16183742)
MGI
Ensembl
PMID:10588860 PMID:16183742 GO_REF:0000107 MGI:3603971 MGI:3687663 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2183141|PMID:12011074)
(MGI:3818355|PMID:17980593)
MGI
Ensembl
PMID:12011074 PMID:17980593 GO_REF:0000107 MGI:2183141 MGI:3818355 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FASLG Fas ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
JBrowse link
G G0S2 G0/G1 switch 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:133,287,065...133,288,066
Ensembl chr 9:133,287,325...133,287,742
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,690,319...49,700,735
Ensembl chr 6:49,690,370...49,701,189
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569
JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:106,570,950...106,627,114
Ensembl chr 4:106,572,755...106,627,418
JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IL12A interleukin 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078
JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within ISO (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840
JBrowse link
G IL4 interleukin 4 acts_upstream_of ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL7 interleukin 7 acts_upstream_of
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709
JBrowse link
G INHBA inhibin subunit beta A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967
JBrowse link
G JAK2 Janus kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5009182|PMID:12426001) MGI
Ensembl
Ensembl
PMID:12426001 GO_REF:0000107 MGI:5009182 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G KRT18 keratin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3711847|PMID:10747083) Ensembl
Ensembl
MGI
PMID:10747083 GO_REF:0000107 MGI:3711847 NCBI chr 5:18,217,686...18,221,432
Ensembl chr 5:18,217,691...18,221,429
JBrowse link
G KRT8 keratin 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3711847|PMID:10747083) Ensembl
Ensembl
MGI
PMID:10747083 GO_REF:0000107 MGI:3711847 NCBI chr 5:18,172,423...18,180,277
Ensembl chr 5:18,167,553...18,180,404
JBrowse link
G LOC100518738 neurotrophin receptor-interacting factor homolog acts_upstream_of_or_within ISO (MGI:1929440|PMID:10545116) MGI PMID:10545116 MGI:1929440 NCBI chr 6:62,833,276...62,882,576
Ensembl chr 6:62,833,620...62,859,088
JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like involved_in ISO (PMID:21785459) UniProt PMID:21785459 NCBI chr14:7,344,788...7,371,086 JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:98,165,990...98,171,674
Ensembl chr 4:98,164,676...98,171,674
JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1930995|PMID:10924506) Ensembl
MGI
PMID:10924506 GO_REF:0000107 MGI:1930995 NCBI chr 2:58,401,542...58,410,414
Ensembl chr 2:58,401,551...58,411,981
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3700102|PMID:17286969) Ensembl
Ensembl
MGI
PMID:17286969 GO_REF:0000107 MGI:3700102 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472
JBrowse link
G PARP2 poly(ADP-ribose) polymerase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2386520|PMID:12065591) Ensembl
Ensembl
MGI
PMID:12065591 GO_REF:0000107 MGI:2386520 NCBI chr 7:78,535,072...78,551,393
Ensembl chr 7:78,535,076...78,551,375
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:3578073|PMID:15858817) MGI
Ensembl
PMID:15858817 GO_REF:0000107 MGI:3578073 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,432,058...39,512,601
JBrowse link
G PIDD1 p53-induced death domain protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603971|PMID:16183742) MGI
Ensembl
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr 2:499,294...505,740
Ensembl chr 2:499,303...504,871
JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1306978|PMID:9806545) Ensembl
Ensembl
MGI
PMID:9806545 GO_REF:0000107 MGI:1306978 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of ISO (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of
involved_in
ISO
IEA
(MGI:80946|PMID:8666928) MGI
Ensembl
PMID:8666928 GO_REF:0000107 MGI:80946 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308
JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3689241|PMID:17015619) MGI
Ensembl
PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chr 4:77,593,204...77,649,551
Ensembl chr 4:77,594,324...77,649,548
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
JBrowse link
G RNF41 ring finger protein 41 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:21,595,703...21,624,589
Ensembl chr 5:21,596,306...21,624,569
JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3040721|PMID:14976225) MGI
Ensembl
PMID:14976225 GO_REF:0000107 MGI:3040721 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748
JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2386810|PMID:12235122) Ensembl
Ensembl
MGI
PMID:12235122 GO_REF:0000107 MGI:2386810 NCBI chr 1:194,351,971...194,380,910
Ensembl chr 1:194,352,001...194,380,907
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor involved_in IEA
IBA
(PMID:21873635) Ensembl
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107
G SMAD3 SMAD family member 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS BHF-UCL
UniProt
GO_REF:0000024 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IEA
BHF-UCL
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341
JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291
JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5510543|PMID:19498109)
(MGI:5521568|PMID:22089168)
MGI
Ensembl
PMID:19498109 PMID:22089168 GO_REF:0000107 MGI:5510543 MGI:5521568 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A acts_upstream_of_or_within ISO (MGI:2667292|PMID:12821115) MGI PMID:12821115 MGI:2667292 NCBI chr 3:39,166,288...39,168,294
Ensembl chr 3:39,166,298...39,168,302
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:69721|PMID:7990930)
Ensembl
GO_Central
Ensembl
MGI
GO_Central
PMID:7990930 PMID:21873635 GO_REF:0000107 MGI:69721 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,147
JBrowse link
G TNFSF12 TNF superfamily member 12 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2667292|PMID:12821115)
GO_Central
Ensembl
GO_Central
MGI
PMID:12821115 PMID:21873635 GO_REF:0000107 MGI:2667292 NCBI chr12:52,843,026...52,853,328
Ensembl chr12:52,843,026...52,853,325
JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:5521568|PMID:22089168)
GO_Central
Ensembl
GO_Central
MGI
PMID:21873635 PMID:22089168 GO_REF:0000107 MGI:5521568 NCBI chr 6:27,797,594...27,804,654
Ensembl chr 6:27,797,607...27,804,423
JBrowse link
G WWOX WW domain containing oxidoreductase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3851310|PMID:19366691) Ensembl
Ensembl
MGI
PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053
JBrowse link
G YAP1 Yes1 associated transcriptional regulator acts_upstream_of
involved_in
ISO
IEA
(MGI:3818355|PMID:17980593) MGI
Ensembl
PMID:17980593 GO_REF:0000107 MGI:3818355 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603
JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2183839|PMID:12115603), (MGI:2675215|PMID:12944463)
(MGI:3029504|PMID:12431371)
(MGI:3032484|PMID:14967141)
Ensembl
Ensembl
MGI
PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 GO_REF:0000107 MGI:2183839 MGI:2675215 MGI:3029504 MGI:3032484 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAG3 BAG cochaperone 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3513163|PMID:11527400) Ensembl
Ensembl
MGI
PMID:11527400 GO_REF:0000107 MGI:3513163 NCBI chr14:129,510,240...129,533,998
Ensembl chr14:129,466,905...129,533,987
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3575206|PMID:15680329)
(MGI:3581932|PMID:15967824)
GO_Central
GO_Central
MGI
PMID:15680329 PMID:15967824 PMID:21873635 MGI:3575206 MGI:3581932 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3581932|PMID:15967824)
(MGI:3575206|PMID:15680329)
GO_Central
Ensembl
GO_Central
MGI
PMID:15680329 PMID:15967824 PMID:21873635 GO_REF:0000107 MGI:3575206 MGI:3581932 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BCL2A1 BCL2 related protein A1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 7:48,887,227...48,897,667
Ensembl chr 7:48,887,094...48,897,870
JBrowse link
G BCL2L1 BCL2 like 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2183839|PMID:12115603)
GO_Central
Ensembl
GO_Central
MGI
Ensembl
PMID:12115603 PMID:21873635 GO_REF:0000107 MGI:2183839 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G BCL2L10 BCL2 like 10 acts_upstream_of ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chr 1:119,594,004...119,607,709 JBrowse link
G BCL2L11 BCL2 like 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581932|PMID:15967824) MGI
Ensembl
PMID:15967824 GO_REF:0000107 MGI:3581932 NCBI chr 3:45,156,791...45,202,996
Ensembl chr 3:45,160,155...45,201,186
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121
JBrowse link
G CASP2 caspase 2 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3691999|PMID:11536012)
GO_Central
Ensembl
GO_Central
MGI
PMID:11536012 PMID:21873635 GO_REF:0000107 MGI:3691999 NCBI chr18:6,946,432...6,966,088
Ensembl chr18:6,941,937...6,966,061
JBrowse link
G CLCN1 chloride voltage-gated channel 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr18:6,902,540...6,941,530
Ensembl chr18:6,902,542...6,940,449
JBrowse link
G COL2A1 collagen type II alpha 1 chain acts_upstream_of
involved_in
ISO
IEA
(MGI:1097047|PMID:9299161) MGI
Ensembl
PMID:9299161 GO_REF:0000107 MGI:1097047 NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718
JBrowse link
G CTNNA1 catenin alpha 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:5315030|PMID:22411810) MGI
Ensembl
PMID:22411810 GO_REF:0000107 MGI:5315030 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 acts_upstream_of ISO (MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI PMID:18322241 PMID:18971423 MGI:3777228 MGI:3833195 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G DHDH dihydrodiol dehydrogenase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:54,210,693...54,217,250
Ensembl chr 6:54,210,609...54,217,285
JBrowse link
G ENSA endosulfine alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,527,902...98,535,647
Ensembl chr 4:98,527,907...98,567,006
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:21,474,218...21,495,040
Ensembl chr 5:21,474,475...21,495,038
JBrowse link
G ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) involved_in IEA Ensembl GO_REF:0000107
G EYA1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3577160|PMID:15817220) MGI
Ensembl
PMID:15817220 GO_REF:0000107 MGI:3577160 NCBI chr 4:63,970,939...64,328,107
Ensembl chr 4:63,970,807...64,328,105
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2158099|PMID:11700312) Ensembl
Ensembl
MGI
PMID:11700312 GO_REF:0000107 MGI:2158099 NCBI chr17:48,930,682...49,243,789
Ensembl chr17:48,966,814...49,243,739
JBrowse link
G FADD Fas associated via death domain involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2675560|PMID:13679421) Ensembl
Ensembl
MGI
PMID:13679421 GO_REF:0000107 MGI:2675560 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
JBrowse link
G FAS Fas cell surface death receptor involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2675560|PMID:13679421)
GO_Central
MGI
GO_Central
PMID:13679421 PMID:21873635 MGI:2675560 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of
involved_in
ISO
IEA
(MGI:3690587|PMID:16956603) MGI
Ensembl
PMID:16956603 GO_REF:0000107 MGI:3690587 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509
JBrowse link
G FOXO3 forkhead box O3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3029504|PMID:12431371) Ensembl
Ensembl
MGI
PMID:12431371 GO_REF:0000107 MGI:3029504 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 6:49,690,319...49,700,735
Ensembl chr 6:49,690,370...49,701,189
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IL1A interleukin 1 alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3691999|PMID:11536012) Ensembl
Ensembl
MGI
PMID:11536012 GO_REF:0000107 MGI:3691999 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
JBrowse link
G IL2 interleukin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2179928|PMID:12082633) Ensembl
Ensembl
MGI
PMID:12082633 GO_REF:0000107 MGI:2179928 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2183839|PMID:12115603)
GO_Central
GO_Central
MGI
PMID:12115603 PMID:21873635 MGI:2183839 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G ITGAV integrin subunit alpha V involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,851
JBrowse link
G ITM2B integral membrane protein 2B acts_upstream_of_or_within ISO (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr11:19,349,088...19,377,931
Ensembl chr11:19,349,134...19,377,917
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3038547|PMID:15039234) Ensembl
Ensembl
MGI
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chr 5:94,016,992...94,110,219
Ensembl chr 5:94,017,387...94,110,214
JBrowse link
G LCN2 lipocalin 2 acts_upstream_of_or_within ISO (MGI:4821076|PMID:16377569) MGI PMID:16377569 MGI:4821076 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644
JBrowse link
G LOC100154044 bcl-2-like protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,765,603...75,770,743
Ensembl chr 7:75,763,078...75,769,763
JBrowse link
G LOC110258578 interleukin-1 beta-like acts_upstream_of_or_within ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999
G MCL1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 4:98,562,092...98,567,014
Ensembl chr 4:98,534,812...98,567,006
JBrowse link
G MKNK1 MAPK interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chr 6:164,887,707...164,933,526
Ensembl chr 6:164,887,748...164,933,521
JBrowse link
G MKNK2 MAPK interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3793518|PMID:17903173) Ensembl
Ensembl
MGI
PMID:17903173 GO_REF:0000107 MGI:3793518 NCBI chr 2:76,510,302...76,522,885
Ensembl chr 2:76,510,303...76,522,883
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr 7:114,571,624...114,574,052 JBrowse link
G NF1 neurofibromin 1 acts_upstream_of ISO (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr12:43,487,098...43,754,205
Ensembl chr12:43,489,813...43,753,969
JBrowse link
G NGF nerve growth factor acts_upstream_of_or_within ISO (MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:2681362 NCBI chr 4:105,256,691...105,307,843
Ensembl chr 4:105,256,749...105,307,837
JBrowse link
G TGFB2 transforming growth factor beta 2 acts_upstream_of ISO (MGI:67124|PMID:8206089) MGI PMID:8206089 MGI:67124 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341
JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3029504|PMID:12431371) Ensembl
Ensembl
MGI
PMID:12431371 GO_REF:0000107 MGI:3029504 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAG3 BAG cochaperone 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10597216) MGI
Ensembl
Ensembl
PMID:10597216 GO_REF:0000107 NCBI chr14:129,510,240...129,533,998
Ensembl chr14:129,466,905...129,533,987
JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1349210|PMID:10597216) MGI
Ensembl
PMID:10597216 GO_REF:0000107 MGI:1349210 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BEX3 brain expressed X-linked 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1859527|PMID:10764727) Ensembl
Ensembl
MGI
PMID:10764727 GO_REF:0000107 MGI:1859527 NCBI chr  X:84,300,645...84,302,124
Ensembl chr  X:84,300,645...84,302,119
JBrowse link
G BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:111,391,083...111,397,609
Ensembl chr14:111,388,898...111,397,594
JBrowse link
G CASP8 caspase 8 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3054336|PMID:15322156)
GO_Central
MGI
GO_Central
PMID:15322156 PMID:21873635 MGI:3054336 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CASP8AP2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1347587|PMID:10235259)
GO_Central
GO_Central
MGI
PMID:10235259 PMID:21873635 MGI:1347587 NCBI chr 1:57,834,251...57,864,837
Ensembl chr 1:57,835,145...57,862,473
JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022
JBrowse link
G DAPK1 death associated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3051747|PMID:15010850)
(MGI:4431305|PMID:20053891)
Ensembl
Ensembl
MGI
PMID:15010850 PMID:20053891 GO_REF:0000107 MGI:3051747 MGI:4431305 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350
JBrowse link
G DAXX death domain associated protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202
JBrowse link
G DDX47 DEAD-box helicase 47 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:59,633,422...59,646,980
Ensembl chr 5:59,633,426...59,650,553
JBrowse link
G DEDD death effector domain containing involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1306907|PMID:9774341) Ensembl
Ensembl
MGI
PMID:9774341 GO_REF:0000107 MGI:1306907 NCBI chr 4:89,311,308...89,323,692
Ensembl chr 4:89,311,310...89,323,724
JBrowse link
G DEDD2 death effector domain containing 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:49,710,948...49,730,457
Ensembl chr 6:49,710,933...49,727,192
JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 2:143,527,865...143,545,862
Ensembl chr 2:143,529,988...143,545,856
JBrowse link
G FADD Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within
involved_in
ISO (MGI:2687085|PMID:12801066), (MGI:3029504|PMID:12431371), (MGI:77677|PMID:8524870)
(MGI:2687085|PMID:12801066), (MGI:3038547|PMID:15039234), (MGI:3576402|PMID:15632112), (MGI:3687663|PMID:10588860), (MGI:3819026|PMID:18363966), (MGI:77677|PMID:8524870)
(MGI:3029504|PMID:12431371)
(MGI:1340173|PMID:10429671)
(MGI:5009197|PMID:10950869)
MGI
BHF-UCL
PMID:8524870 PMID:10429671 PMID:10588860 PMID:10950869 PMID:12431371 More... MGI:1340173 MGI:2687085 MGI:3029504 MGI:3038547 MGI:3576402 MGI:3687663 MGI:3819026 MGI:5009197 MGI:77677 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FASLG Fas ligand involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(PMID:26582200)
(MGI:3038547|PMID:15039234), (MGI:3687663|PMID:10588860)
GO_Central
GO_Central
Ensembl
MGI
RGD
PMID:10588860 PMID:15039234 PMID:16689665 PMID:21873635 PMID:26582200 GO_REF:0000107 MGI:3038547 MGI:3687663 RGD:1582444 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,596,130...52,598,166
Ensembl chr12:52,596,543...52,598,194
JBrowse link
G HMGB2 high mobility group box 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:3831045|PMID:19139395) MGI
Ensembl
PMID:19139395 GO_REF:0000107 MGI:3831045 NCBI chr14:16,709,966...16,712,288
Ensembl chr14:16,710,047...16,717,101
JBrowse link
G IL18 interleukin 18 involved_in IDA (PMID:11429161) UniProt
UniProt
PMID:11429161 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
JBrowse link
G ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of
involved_in
ISO
IEA
(MGI:4431305|PMID:20053891) MGI
Ensembl
PMID:20053891 GO_REF:0000107 MGI:4431305 NCBI chr14:115,243,035...115,278,137
Ensembl chr14:115,252,791...115,277,654
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like ISO RGD PMID:19934367 RGD:4142856 NCBI chr14:7,344,788...7,371,086 JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr 7:114,571,624...114,574,052 JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr12:43,487,098...43,754,205
Ensembl chr12:43,489,813...43,753,969
JBrowse link
G NGF nerve growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,256,691...105,307,843
Ensembl chr 4:105,256,749...105,307,837
JBrowse link
G PHF23 PHD finger protein 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,590,801...52,595,208
Ensembl chr12:52,590,804...52,595,266
JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3603971|PMID:16183742) Ensembl
Ensembl
MGI
PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr 2:499,294...505,740
Ensembl chr 2:499,303...504,871
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3038547|PMID:15039234) Ensembl
Ensembl
MGI
PMID:15039234 GO_REF:0000107 MGI:3038547 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609
JBrowse link
G POU2F2 POU class 2 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,791,937...49,829,771
Ensembl chr 6:49,727,012...49,825,816
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of
involved_in
ISO
IEA
(MGI:3612236|PMID:16365167) MGI
Ensembl
PMID:16365167 GO_REF:0000107 MGI:3612236 NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829
JBrowse link
G RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 involved_in IEA Ensembl GO_REF:0000107
G ROCK2 Rho associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,352,920...125,493,362
JBrowse link
G SKIL SKI like proto-oncogene acts_upstream_of
involved_in
ISO
IEA
(MGI:1858539|PMID:10811619) MGI
Ensembl
PMID:10811619 GO_REF:0000107 MGI:1858539 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,173
JBrowse link
G SORT1 sortilin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:110,721,110...110,791,406
Ensembl chr 4:110,720,947...110,789,070
JBrowse link
G STK3 serine/threonine kinase 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:4420852|PMID:20080598) MGI
Ensembl
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 4:38,011,802...38,306,777
Ensembl chr 4:38,011,814...38,306,773
JBrowse link
G STK4 serine/threonine kinase 4 acts_upstream_of
involved_in
ISO
IEA
(MGI:4420852|PMID:20080598) MGI
Ensembl
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr17:47,387,594...47,475,705
Ensembl chr17:47,387,600...47,475,718
JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:4420852|PMID:20080598)
(PMID:21873635)
(MGI:3029504|PMID:12431371)
Ensembl
MGI
GO_Central
Ensembl
GO_Central
PMID:12431371 PMID:20080598 PMID:21873635 GO_REF:0000107 MGI:3029504 MGI:4420852 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR3 fibroblast growth factor receptor 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:879,151...894,968
Ensembl chr 8:879,159...894,964
JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBE4B ubiquitination factor E4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:70,345,789...70,462,434
Ensembl chr 6:70,345,813...70,462,434
JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone ISO RGD PMID:11790788 RGD:1358682 NCBI chr 4:68,481,696...68,486,122
Ensembl chr 4:68,484,053...68,486,121
JBrowse link
G ESR2 estrogen receptor 2 acts_upstream_of_or_within ISO (MGI:3047056|PMID:15187231) MGI PMID:15187231 MGI:3047056 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
JBrowse link
G METTL21C methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within ISO (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chr11:71,008,854...71,021,640
Ensembl chr11:71,008,846...71,020,730
JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOPT1 apoptogenic 1, mitochondrial acts_upstream_of_or_within ISO (MGI:3694393|PMID:16782708) MGI PMID:16782708 MGI:3694393
G BAD BCL2 associated agonist of cell death involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of
involved_in
ISO
IEA
(MGI:3692043|PMID:14502238) MGI
Ensembl
PMID:14502238 GO_REF:0000107 MGI:3692043 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BBC3 BCL2 binding component 3 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BCL2L10 BCL2 like 10 acts_upstream_of ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chr 1:119,594,004...119,607,709 JBrowse link
G BNIP3 BCL2 interacting protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3696331|PMID:16954213) MGI
Ensembl
PMID:16954213 GO_REF:0000107 MGI:3696331 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907
JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of ISO (MGI:3790365|PMID:17938250) MGI PMID:17938250 MGI:3790365 NCBI chr 3:45,585,188...45,623,240
Ensembl chr 3:45,585,226...45,624,543
JBrowse link
G CLU clusterin involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764
JBrowse link
G COPS3 COP9 signalosome subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:61,000,562...61,023,920
Ensembl chr12:60,994,310...61,024,846
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202
JBrowse link
G FLCN folliculin acts_upstream_of
involved_in
ISO
IEA
(MGI:5050037|PMID:21258407) MGI
Ensembl
PMID:21258407 GO_REF:0000107 MGI:5050037 NCBI chr12:61,029,186...61,045,400
Ensembl chr12:61,031,157...61,045,392
JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3696331|PMID:16954213) Ensembl
Ensembl
MGI
PMID:16954213 GO_REF:0000107 MGI:3696331 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G HTRA2 HtrA serine peptidase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3511636|PMID:15509788) MGI
Ensembl
PMID:15509788 GO_REF:0000107 MGI:3511636 NCBI chr 3:68,516,666...68,520,025
Ensembl chr 3:68,516,500...68,519,886
JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:84,852,782...84,858,072
Ensembl chr 6:84,852,793...84,857,982
JBrowse link
G IVNS1ABP influenza virus NS1A binding protein acts_upstream_of
involved_in
ISO
IEA
(MGI:4819697|PMID:15485691) MGI
Ensembl
PMID:15485691 GO_REF:0000107 MGI:4819697 NCBI chr 9:126,459,542...126,480,126
Ensembl chr 9:126,453,155...126,479,587
JBrowse link
G LGALS12 galectin 12 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(PMID:11435439)
GO_Central
GO_Central
Ensembl
MGI
PMID:11435439 PMID:21873635 GO_REF:0000107 NCBI chr 2:8,454,362...8,475,360
Ensembl chr 2:8,463,402...8,475,162
JBrowse link
G LOC100522887 caspase-13 involved_in ISO (PMID:15123740) ParkinsonsUK-UCL PMID:15123740 NCBI chr 9:35,167,567...35,185,791 JBrowse link
G LOC100523672 heat shock factor protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:27,808,658...27,818,256
Ensembl chr 6:27,808,652...27,818,750
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:98,165,990...98,171,674
Ensembl chr 4:98,164,676...98,171,674
JBrowse link
G MSH6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677657|PMID:14632208) MGI
Ensembl
PMID:14632208 GO_REF:0000107 MGI:2677657 NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS AgBase
AgBase
GO_REF:0000024 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G NBN nibrin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3805397|PMID:18614044) Ensembl
Ensembl
MGI
PMID:18614044 GO_REF:0000107 MGI:3805397 NCBI chr 4:46,787,664...46,854,331
Ensembl chr 4:46,787,691...46,874,603
JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO (MGI:5315351|PMID:15863367) UniProt PMID:15863367 MGI:5315351 NCBI chr13:86,836,288...86,869,569
Ensembl chr13:86,834,587...86,869,297
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711) UniProt PMID:14500711 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr14:50,040,612...50,083,047
Ensembl chr14:50,040,663...50,063,325
JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (MGI:2671671|PMID:12928424) MGI PMID:12928424 MGI:2671671 NCBI chr12:12,882,287...13,268,647
Ensembl chr12:12,882,064...13,263,554
JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1932564|PMID:10859351) Ensembl
Ensembl
MGI
PMID:10859351 GO_REF:0000107 MGI:1932564 NCBI chr 1:194,351,971...194,380,910
Ensembl chr 1:194,352,001...194,380,907
JBrowse link
G SIRT1 sirtuin 1 involved_in IMP (PMID:23313858) AgBase
AgBase
PMID:23313858 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor involved_in
NOT|involved_in
ISO (PMID:12011449) BHF-UCL PMID:12011449
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1344924|PMID:10479688) MGI
Ensembl
PMID:10479688 GO_REF:0000107 MGI:1344924 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121
JBrowse link
G CASP6 caspase 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045
JBrowse link
G CEP63 centrosomal protein 63 acts_upstream_of ISO (MGI:5662131|PMID:26158450) MGI PMID:26158450 MGI:5662131 NCBI chr13:75,605,622...75,707,087
Ensembl chr13:75,605,675...75,707,102
JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:14,571,712...14,580,740
Ensembl chr12:14,571,951...14,580,742
JBrowse link
G E2F1 E2F transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927703|PMID:11095619) Ensembl
Ensembl
MGI
PMID:11095619 GO_REF:0000107 MGI:1927703 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883
JBrowse link
G E2F2 E2F transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927703|PMID:11095619) Ensembl
Ensembl
MGI
PMID:11095619 GO_REF:0000107 MGI:1927703 NCBI chr 6:81,377,922...81,398,862
Ensembl chr 6:81,377,924...81,398,867
JBrowse link
G EDA2R ectodysplasin A2 receptor acts_upstream_of_or_within ISO (MGI:4454200|PMID:20434500) MGI PMID:20434500 MGI:4454200 NCBI chr  X:52,522,231...52,533,080 JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr13:41,443,963...42,884,799
Ensembl chr13:41,443,965...42,392,817
JBrowse link
G HINT1 histidine triad nucleotide binding protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:133,469,765...133,475,813
Ensembl chr 2:133,467,151...133,475,454
JBrowse link
G JMY junction mediating and regulatory protein, p53 cofactor acts_upstream_of_or_within ISO (MGI:1891484|PMID:10518217) MGI PMID:10518217 MGI:1891484 NCBI chr 2:88,021,572...88,098,522
Ensembl chr 2:88,022,936...88,089,403
JBrowse link
G LOC100522011 apoptosis-associated speck-like protein containing a CARD involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
JBrowse link
G MYBBP1A MYB binding protein 1a involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:50,491,042...50,506,085
Ensembl chr12:50,491,044...50,506,050
JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:26,274,562...26,295,787
Ensembl chr12:26,274,606...26,301,878
JBrowse link
G PERP p53 apoptosis effector related to PMP22 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1929912|PMID:10733530) Ensembl
Ensembl
MGI
PMID:10733530 GO_REF:0000107 MGI:1929912 NCBI chr 1:26,301,254...26,317,046
Ensembl chr 1:26,301,252...26,317,868
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)
UniProt PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
JBrowse link
G PML PML nuclear body scaffold acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3034149|PMID:14992722) MGI
Ensembl
PMID:14992722 GO_REF:0000107 MGI:3034149 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:50,729,746...50,732,626
Ensembl chr11:50,730,428...50,732,539
JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr 8:82,044,443...82,046,377
Ensembl chr 8:82,043,643...82,047,675
JBrowse link
G PPP1R13B protein phosphatase 1 regulatory subunit 13B involved_in IEA Ensembl
Ensembl
GO_REF:0000107
G RRN3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of
involved_in
ISO
IEA
(MGI:3583493|PMID:15989966) MGI
Ensembl
PMID:15989966 GO_REF:0000107 MGI:3583493 NCBI chr 3:7,537,131...7,571,990
Ensembl chr 3:7,537,133...7,571,992
JBrowse link
G RRP8 ribosomal RNA processing 8 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:3,152,162...3,169,380
Ensembl chr 9:3,152,209...3,162,540
JBrowse link
G SHISA5 shisa family member 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2183272|PMID:12135983) MGI
Ensembl
PMID:12135983 GO_REF:0000107 MGI:2183272 NCBI chr13:31,180,844...31,205,724
Ensembl chr13:31,180,846...31,205,731
JBrowse link
G STK11 serine/threonine kinase 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327
JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2183272|PMID:12135983), (MGI:3589512|PMID:16107883)
(MGI:4454200|PMID:20434500)
MGI
Ensembl
PMID:12135983 PMID:16107883 PMID:20434500 GO_REF:0000107 MGI:2183272 MGI:3589512 MGI:4454200 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TP53BP2 tumor protein p53 binding protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:19,823,932...19,889,883
Ensembl chr10:19,823,936...19,889,869
JBrowse link
G WWOX WW domain containing oxidoreductase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1930321|PMID:11058590) Ensembl
Ensembl
MGI
PMID:11058590 GO_REF:0000107 MGI:1930321 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053
JBrowse link
G ZNF385B zinc finger protein 385B involved_in ISO (PMID:22945289) UniProt PMID:22945289 NCBI chr15:85,041,947...85,469,112
Ensembl chr15:85,045,799...85,367,021
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399
JBrowse link
G ATM ATM serine/threonine kinase acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:1926715|PMID:11040211), (MGI:3652689|PMID:16777961)
(PMID:21873635)
(MGI:3714678|PMID:17476307)
MGI
GO_Central
Ensembl
GO_Central
PMID:11040211 PMID:16777961 PMID:17476307 PMID:21873635 GO_REF:0000107 MGI:1926715 MGI:3652689 MGI:3714678 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,552
JBrowse link
G BAD BCL2 associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3029504|PMID:12431371)
(MGI:3057092|PMID:15231831)
Ensembl
Ensembl
MGI
PMID:12431371 PMID:15231831 GO_REF:0000107 MGI:3029504 MGI:3057092 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
GO_Central
GO_Central
MGI
PMID:15901672 PMID:15967824 PMID:21873635 MGI:3581932 MGI:3689797 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2675761|PMID:12952892)
(MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
GO_Central
Ensembl
GO_Central
MGI
PMID:12952892 PMID:15901672 PMID:15967824 PMID:21873635 GO_REF:0000107 MGI:2675761 MGI:3581932 MGI:3689797 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BCL2A1 BCL2 related protein A1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 7:48,887,227...48,897,667
Ensembl chr 7:48,887,094...48,897,870
JBrowse link
G BCL2L1 BCL2 like 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2677658|PMID:14517295)
GO_Central
Ensembl
GO_Central
MGI
Ensembl
PMID:14517295 PMID:21873635 GO_REF:0000107 MGI:2677658 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G BCL2L11 BCL2 like 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11546872)
(MGI:3581932|PMID:15967824)
MGI
Ensembl
PMID:11546872 PMID:15967824 GO_REF:0000107 MGI:3581932 NCBI chr 3:45,156,791...45,202,996
Ensembl chr 3:45,160,155...45,201,186
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121
JBrowse link
G BRCA1 BRCA1 DNA repair associated acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14654789) MGI
Ensembl
Ensembl
PMID:14654789 GO_REF:0000107 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668
JBrowse link
G BRCA2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:3714678|PMID:17476307) MGI PMID:17476307 MGI:3714678 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G CASP2 caspase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr18:6,946,432...6,966,088
Ensembl chr18:6,941,937...6,966,061
JBrowse link
G CASP9 caspase 9 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CHEK2 checkpoint kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290
JBrowse link
G CLCN1 chloride voltage-gated channel 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr18:6,902,540...6,941,530
Ensembl chr18:6,902,542...6,940,449
JBrowse link
G DHDH dihydrodiol dehydrogenase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:54,210,693...54,217,250
Ensembl chr 6:54,210,609...54,217,285
JBrowse link
G E2F1 E2F transcription factor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883
JBrowse link
G EI24 EI24 autophagy associated transmembrane protein acts_upstream_of_or_within ISO (MGI:1350723|PMID:10594026) MGI PMID:10594026 MGI:1350723 NCBI chr 9:52,704,560...52,724,966
Ensembl chr 9:52,704,570...52,720,938
JBrowse link
G ENSA endosulfine alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,527,902...98,535,647
Ensembl chr 4:98,527,907...98,567,006
JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:75,251,465...75,279,364
Ensembl chr 6:75,251,467...75,279,314
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1913261|PMID:11005836) Ensembl
MGI
PMID:11005836 GO_REF:0000107 MGI:1913261 NCBI chr14:89,998,125...90,075,911
Ensembl chr14:90,002,024...90,075,898
JBrowse link
G FNIP2 folliculin interacting protein 2 involved_in ISO (MGI:5284752|PMID:19137017) UniProt PMID:19137017 MGI:5284752 NCBI chr 8:47,702,877...47,838,541
Ensembl chr 8:47,702,961...47,838,535
JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 involved_in IEA Ensembl
InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr12:48,167,861...48,172,540
Ensembl chr12:48,168,900...48,172,636
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:11854317 RGD:625692
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:68,516,666...68,520,025
Ensembl chr 3:68,516,500...68,519,886
JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3775338|PMID:11753682) MGI
Ensembl
PMID:11753682 GO_REF:0000107 MGI:3775338 NCBI chr 7:23,265,560...23,266,905
Ensembl chr 7:23,265,564...23,266,827
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:67,123,055...67,147,991
Ensembl chr 9:67,123,265...67,147,989
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G LOC110258364 cysteine-rich protein 1 involved_in ISO (PMID:20415737) UniProt PMID:20415737
G MAEL maelstrom spermatogenic transposon silencer involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3813746|PMID:18694567) Ensembl
Ensembl
MGI
PMID:18694567 GO_REF:0000107 MGI:3813746 NCBI chr 4:83,990,266...84,040,465
Ensembl chr 4:83,990,273...84,040,465
JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (MGI:2678630|PMID:14562041) MGI PMID:14562041 MGI:2678630 NCBI chr13:68,816,677...68,828,559
Ensembl chr13:68,816,679...68,828,580
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3689797|PMID:15901672)
GO_Central
GO_Central
Ensembl
MGI
PMID:15901672 PMID:21873635 GO_REF:0000107 MGI:3689797 NCBI chr 4:98,562,092...98,567,014
Ensembl chr 4:98,534,812...98,567,006
JBrowse link
G MLH1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2678630|PMID:14562041) MGI
Ensembl
Ensembl
PMID:14562041 GO_REF:0000107 MGI:2678630 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr 7:114,571,624...114,574,052 JBrowse link
G MSH2 mutS homolog 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1334080|PMID:10097137)
(MGI:3029112|PMID:14744764)
MGI
Ensembl
PMID:10097137 PMID:14744764 GO_REF:0000107 MGI:1334080 MGI:3029112 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585
JBrowse link
G MSH6 mutS homolog 6 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3053495|PMID:15324697)
GO_Central
Ensembl
MGI
PMID:15324697 PMID:21873635 GO_REF:0000107 MGI:3053495 NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G NFATC4 nuclear factor of activated T cells 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709926|PMID:17242187) Ensembl
Ensembl
MGI
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chr 7:74,918,982...74,929,688
Ensembl chr 7:74,918,984...74,929,600
JBrowse link
G PCBP4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr13:34,090,015...34,099,959
Ensembl chr13:34,090,020...34,099,886
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709926|PMID:17242187) Ensembl
Ensembl
MGI
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3580934|PMID:15626733)
(MGI:1306978|PMID:9806545)
GO_Central
GO_Central
Ensembl
MGI
PMID:9806545 PMID:15626733 PMID:21873635 GO_REF:0000107 MGI:1306978 MGI:3580934 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G POLB DNA polymerase beta involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1334987|PMID:10197627) Ensembl
Ensembl
MGI
PMID:10197627 GO_REF:0000107 MGI:1334987 NCBI chr17:11,356,130...11,388,122
Ensembl chr17:11,356,129...11,388,821
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2450507|PMID:12604618)
GO_Central
GO_Central
Ensembl
MGI
PMID:12604618 PMID:21873635 GO_REF:0000107 MGI:2450507 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656
JBrowse link
G RAD9A RAD9 checkpoint clamp component A acts_upstream_of
involved_in
ISO
IEA
(MGI:3584078|PMID:15983387) MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chr 2:5,123,142...5,129,740
Ensembl chr 2:5,123,134...5,129,703
JBrowse link
G SFN stratifin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:84,188,521...84,189,824
Ensembl chr 6:84,188,445...84,189,827
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297
JBrowse link
G SKIL SKI like proto-oncogene acts_upstream_of
involved_in
ISO
IEA
(MGI:1858539|PMID:10811619) MGI
Ensembl
PMID:10811619 GO_REF:0000107 MGI:1858539 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,173
JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:3691744|PMID:15642323) MGI PMID:15642323 MGI:3691744 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709926|PMID:17242187) Ensembl
Ensembl
MGI
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709926|PMID:17242187) Ensembl
Ensembl
MGI
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:3709926|PMID:17242187)
Ensembl
GO_Central
Ensembl
MGI
GO_Central
PMID:17242187 PMID:21873635 GO_REF:0000107 MGI:3709926 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,147
JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,865,967...33,878,135
Ensembl chr10:33,865,959...33,879,070
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 1:168,353,655...168,453,175
Ensembl chr 1:168,350,557...168,453,344
JBrowse link
G USP47 ubiquitin specific peptidase 47 acts_upstream_of
involved_in
ISO
IEA
(MGI:4839431|PMID:19966869) MGI
Ensembl
PMID:19966869 GO_REF:0000107 MGI:4839431 NCBI chr 2:47,449,162...47,583,893
Ensembl chr 2:47,449,161...47,582,819
JBrowse link
G XPA XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO (MGI:1913261|PMID:11005836) MGI PMID:11005836 MGI:1913261 NCBI chr 1:239,532,331...239,568,589
Ensembl chr 1:239,532,272...239,568,570
JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:84,153,854...84,183,772
Ensembl chr 6:84,153,838...84,182,305
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AEN apoptosis enhancing nuclease involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:191,200,625...191,211,884
Ensembl chr 1:191,200,632...191,219,961
JBrowse link
G ATAD5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399
JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,899...23,775,892
JBrowse link
G BBC3 BCL2 binding component 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603103|PMID:16151013) MGI
Ensembl
PMID:16151013 GO_REF:0000107 MGI:3603103 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16384933) MGI
Ensembl
Ensembl
PMID:16384933 GO_REF:0000107 NCBI chr 6:51,256,033...51,264,923
Ensembl chr 6:51,256,033...51,265,351
JBrowse link
G BRCA2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:3579926|PMID:15735671)
(MGI:3714678|PMID:17476307)
MGI PMID:15735671 PMID:17476307 MGI:3579926 MGI:3714678 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G CDIP1 cell death inducing p53 target 1 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(PMID:17599062)
(PMID:21873635)
MGI
GO_Central
Ensembl
Ensembl
PMID:17599062 PMID:21873635 GO_REF:0000107 NCBI chr 3:37,815,259...37,839,266
Ensembl chr 3:37,815,710...37,839,009
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2675761|PMID:12952892) Ensembl
Ensembl
MGI
PMID:12952892 GO_REF:0000107 MGI:2675761 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CHEK2 checkpoint kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1354114|PMID:10710310) MGI
Ensembl
Ensembl
PMID:10710310 GO_REF:0000107 MGI:1354114 NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290
JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:75,117,708...75,119,907
Ensembl chr14:75,117,710...75,119,902
JBrowse link
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:32,047,614...32,064,231
Ensembl chr 5:32,047,643...32,064,222
JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 acts_upstream_of
involved_in
ISO
IEA
(MGI:5438719|PMID:22768269) MGI
Ensembl
PMID:22768269 GO_REF:0000107 MGI:5438719 NCBI chr 1:127,781,357...127,784,803
Ensembl chr 1:127,781,403...127,784,843
JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3619785|PMID:16537918)
GO_Central
Ensembl
GO_Central
MGI
Ensembl
PMID:16537918 PMID:21873635 GO_REF:0000107 MGI:3619785 NCBI chr 4:106,570,950...106,627,114
Ensembl chr 4:106,572,755...106,627,418
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3619785|PMID:16537918)
GO_Central
Ensembl
GO_Central
MGI
PMID:16537918 PMID:21873635 GO_REF:0000107 MGI:3619785 NCBI chr18:9,940,535...10,141,815
Ensembl chr18:9,861,792...10,135,065
JBrowse link
G LOC100522011 apoptosis-associated speck-like protein containing a CARD involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
JBrowse link
G MSH2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:1334080|PMID:10097137)
(PMID:21873635)
Ensembl
Ensembl
MGI
GO_Central
PMID:10097137 PMID:21873635 GO_REF:0000107 MGI:1334080 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3784021|PMID:11896600) Ensembl
Ensembl
MGI
PMID:11896600 GO_REF:0000107 MGI:3784021 NCBI chr 3:18,402,781...18,404,411
Ensembl chr 3:18,402,935...18,511,087
JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,824,181...23,827,428
Ensembl chr10:23,826,874...23,827,245
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:1858284|PMID:10807576) MGI PMID:10807576 MGI:1858284 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430
G RPS27L ribosomal protein S27 like involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:108,881,330...108,886,334
Ensembl chr 1:108,881,552...108,890,283
JBrowse link
G SHISA5 shisa family member 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2183272|PMID:12135983) Ensembl
Ensembl
MGI
PMID:12135983 GO_REF:0000107 MGI:2183272 NCBI chr13:31,180,844...31,205,724
Ensembl chr13:31,180,846...31,205,731
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297
JBrowse link
G SNW1 SNW domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:100,718,298...100,749,414
Ensembl chr 7:100,718,036...100,749,356
JBrowse link
G TMEM109 transmembrane protein 109 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:4437179|PMID:20060811)
GO_Central
GO_Central
Ensembl
MGI
PMID:20060811 PMID:21873635 GO_REF:0000107 MGI:4437179 NCBI chr 2:10,828,644...10,837,124
Ensembl chr 2:10,828,652...10,837,062
JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3578084|PMID:15735665) Ensembl
Ensembl
MGI
PMID:15735665 GO_REF:0000107 MGI:3578084 NCBI chr10:33,865,967...33,878,135
Ensembl chr10:33,865,959...33,879,070
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3584078|PMID:15983387)
(PMID:14654789), (PMID:14744935)
(MGI:2675761|PMID:12952892)
(MGI:2183272|PMID:12135983)
(MGI:3690827|PMID:16286009)
(MGI:3714678|PMID:17476307)
(MGI:3652689|PMID:16777961)
Ensembl
MGI
Ensembl
PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... GO_REF:0000107 MGI:2183272 MGI:2675761 MGI:3584078 MGI:3652689 MGI:3690827 MGI:3714678 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3693137|PMID:17122775) Ensembl
Ensembl
MGI
PMID:17122775 GO_REF:0000107 MGI:3693137 NCBI chr13:127,115,990...127,347,082
Ensembl chr13:127,116,105...127,347,068
JBrowse link
G TP73 tumor protein p73 involved_in
acts_upstream_of
IEA
ISO
(MGI:3584078|PMID:15983387) Ensembl
MGI
Ensembl
PMID:15983387 GO_REF:0000107 MGI:3584078 NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990
JBrowse link
G USP28 ubiquitin specific peptidase 28 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,417,560...41,481,044
Ensembl chr 9:41,417,564...41,480,994
JBrowse link
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,520...106,708,317
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
JBrowse link
G ATF4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,545,064...18,568,312
Ensembl chr 3:18,545,071...18,568,310
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:49,980,488...50,014,006
Ensembl chr12:49,980,497...50,025,171
JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA
ISS
Ensembl
Ensembl
UniProt
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,899...23,775,892
JBrowse link
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:2667259|PMID:12847083)
(MGI:3575207|PMID:15776018)
MGI PMID:12847083 PMID:15776018 MGI:2667259 MGI:3575207 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3575207|PMID:15776018)
(MGI:2667259|PMID:12847083)
MGI
Ensembl
PMID:12847083 PMID:15776018 GO_REF:0000107 MGI:2667259 MGI:3575207 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BBC3 BCL2 binding component 3 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BRSK2 BR serine/threonine kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:896,720...953,908
Ensembl chr 2:896,585...953,108
JBrowse link
G CEBPB CCAAT enhancer binding protein beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305
JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:130,360,510...130,363,332
Ensembl chr 1:130,360,514...130,363,308
JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022
JBrowse link
G DDIT3 DNA damage inducible transcript 3 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2158984|PMID:11854325)
GO_Central
GO_Central
Ensembl
MGI
PMID:11854325 PMID:21873635 GO_REF:0000107 MGI:2158984 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
G DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:88,198,751...88,256,396
Ensembl chr15:88,198,794...88,259,002
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (MGI:2136067|PMID:11430819) MGI PMID:11430819 MGI:2136067 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1929557|PMID:11146108)
GO_Central
GO_Central
Ensembl
MGI
PMID:11146108 PMID:21873635 GO_REF:0000107 MGI:1929557 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1346198|PMID:9755171)
GO_Central
Ensembl
GO_Central
MGI
Ensembl
PMID:9755171 PMID:21873635 GO_REF:0000107 MGI:1346198 NCBI chr 3:22,510,067...22,537,872
Ensembl chr 3:22,510,558...22,537,868
JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha involved_in IEA
ISS
Ensembl
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:182,268,651...182,318,147
Ensembl chr 1:182,265,261...182,318,195
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:5619738|PMID:23028846) CACAO PMID:23028846 MGI:5619738 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569
JBrowse link
G ICAM2 intercellular adhesion molecule 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:14,986,636...14,991,639
Ensembl chr12:14,972,852...14,997,428
JBrowse link
G INS insulin acts_upstream_of_or_within ISO (MGI:2158984|PMID:11854325) MGI PMID:11854325 MGI:2158984 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G LOC100522887 caspase-13 involved_in ISO (PMID:15123740) ParkinsonsUK-UCL PMID:15123740 NCBI chr 9:35,167,567...35,185,791 JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,493
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4836774|PMID:20811152) MGI
Ensembl
PMID:20811152 GO_REF:0000107 MGI:4836774 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:5621265 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4849347|PMID:21030605) Ensembl
Ensembl
MGI
PMID:21030605 GO_REF:0000107 MGI:4849347 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G QRICH1 glutamine rich 1 involved_in ISO (PMID:33384352) UniProt PMID:33384352 NCBI chr13:31,663,812...31,714,523
Ensembl chr13:31,658,642...31,714,455
JBrowse link
G RNF186 ring finger protein 186 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:78,195,692...78,199,058
Ensembl chr 6:78,192,337...78,198,597
JBrowse link
G SELENOK selenoprotein K involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,989,461...35,996,824
Ensembl chr13:35,990,182...35,996,853
JBrowse link
G SPOP speckle type BTB/POZ protein acts_upstream_of ISO (MGI:4836774|PMID:20811152) MGI PMID:20811152 MGI:4836774 NCBI chr12:25,792,621...25,860,630
Ensembl chr12:25,792,630...25,860,595
JBrowse link
G SYVN1 synoviolin 1 acts_upstream_of ISO (MGI:3575050|PMID:15611074) MGI PMID:15611074 MGI:3575050 NCBI chr 2:7,059,444...7,066,617
Ensembl chr 2:7,059,462...7,066,601
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3050914|PMID:15304216) Ensembl
Ensembl
MGI
PMID:15304216 GO_REF:0000107 MGI:3050914 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936
JBrowse link
G TMEM117 transmembrane protein 117 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:74,917,081...75,402,839
Ensembl chr 5:74,917,463...75,406,367
JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:34,808,273...34,819,592
Ensembl chr17:34,807,582...34,816,451
JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within ISO PMID:18710920 MGI PMID:18710920 RGD:8554156 NCBI chr 8:30,887,784...30,961,685
Ensembl chr 8:30,887,830...30,963,762
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:3840374 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDCD10 programmed cell death 10 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:106,517,408...106,558,959
Ensembl chr13:106,517,432...106,558,895
JBrowse link
G STK25 serine/threonine kinase 25 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:140,144,334...140,154,361
Ensembl chr15:140,144,336...140,154,366
JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:80,984,969...81,076,573
Ensembl chr15:80,985,126...81,081,014
JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4867601|PMID:20935145) Ensembl
Ensembl
MGI
PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDIT3 DNA damage inducible transcript 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G LOC100515171 sodium channel protein type 2 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2179539|PMID:10827969) Ensembl
Ensembl
MGI
PMID:10827969 GO_REF:0000107 MGI:2179539 NCBI chr15:71,864,753...71,999,219
Ensembl chr15:71,864,739...71,999,212
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 acts_upstream_of
involved_in
ISO
IEA
(MGI:3654719|PMID:16571598) MGI
Ensembl
PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,713...117,472,005
JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member ISO protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:50,509,777...50,538,004
Ensembl chr13:50,509,519...50,538,966
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,205,683
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3587135|PMID:16085184)
GO_Central
Ensembl
GO_Central
MGI
PMID:16085184 PMID:21873635 GO_REF:0000107 MGI:3587135 NCBI chr14:30,498,885...30,519,846
Ensembl chr14:30,498,900...30,520,070
JBrowse link
G GPX1 glutathione peroxidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2153292|PMID:11562367), (MGI:3613414|PMID:15663476)
(MGI:3698597|PMID:16373599)
MGI
Ensembl
PMID:11562367 PMID:15663476 PMID:16373599 GO_REF:0000107 MGI:2153292 MGI:3613414 MGI:3698597 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GSKIP GSK3B interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:117,586,742...117,607,575
Ensembl chr 7:117,586,764...117,607,564
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:15659221 RGD:1641883 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3829088|PMID:18948261)
GO_Central
GO_Central
Ensembl
MGI
PMID:18948261 PMID:21873635 GO_REF:0000107 MGI:3829088 NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,493
JBrowse link
G MAPT microtubule associated protein tau ISO RGD PMID:12420308 RGD:8158111 NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,373
JBrowse link
G MELK maternal embryonic leucine zipper kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3829088|PMID:18948261) Ensembl
Ensembl
MGI
PMID:18948261 GO_REF:0000107 MGI:3829088 NCBI chr 1:237,317,161...237,431,522
Ensembl chr 1:237,317,191...237,431,589
JBrowse link
G NOX1 NADPH oxidase 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:4881403|PMID:19661248) MGI
Ensembl
PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,667...82,586,532
JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:78,608,394...78,650,958
Ensembl chr15:78,608,432...78,652,962
JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4849347|PMID:21030605) Ensembl
Ensembl
MGI
PMID:21030605 GO_REF:0000107 MGI:4849347 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G RNF7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) MGI PMID:10082581 MGI:1333612 NCBI chr13:82,548,475...82,554,888
Ensembl chr13:82,548,421...82,555,685
JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:3691744|PMID:15642323) MGI PMID:15642323 MGI:3691744 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G STK24 serine/threonine kinase 24 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:67,458,350...67,565,642
Ensembl chr11:67,458,351...67,634,349
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 1:168,353,655...168,453,175
Ensembl chr 1:168,350,557...168,453,344
JBrowse link
G ZNF622 zinc finger protein 622 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:5,699,740...5,714,824
Ensembl chr16:5,699,744...5,714,516
JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BID BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5566519|PMID:20436477) Ensembl
Ensembl
MGI
PMID:20436477 GO_REF:0000107 MGI:5566519 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853
JBrowse link
G BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:111,391,083...111,397,609
Ensembl chr14:111,388,898...111,397,594
JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907
JBrowse link
G BNIP3L BCL2 interacting protein 3 like involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr14:10,318,688...10,345,689
Ensembl chr14:10,318,732...10,345,679
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2158099|PMID:11700312) Ensembl
Ensembl
MGI
PMID:11700312 GO_REF:0000107 MGI:2158099 NCBI chr17:48,930,682...49,243,789
Ensembl chr17:48,966,814...49,243,739
JBrowse link
G RHOT1 ras homolog family member T1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:42,711,231...42,783,471
Ensembl chr12:42,711,233...42,783,421
JBrowse link
G RHOT2 ras homolog family member T2 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 3:41,100,876...41,106,370
Ensembl chr 3:41,100,879...41,106,418
JBrowse link
G RTL10 retrotransposon Gag like 10 involved_in ISO (PMID:23055042) UniProt PMID:23055042 NCBI chr14:51,338,134...51,342,383 JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:77,679,287...77,737,657
Ensembl chr14:77,636,149...77,737,654
JBrowse link
G VDAC2 voltage dependent anion channel 2 involved_in ISS
IEA
UniProt
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr14:77,767,165...77,782,327
Ensembl chr14:77,766,686...77,782,322
JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATF apoptosis antagonizing transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4359364|PMID:17488777) Ensembl
Ensembl
MGI
PMID:17488777 GO_REF:0000107 MGI:4359364 NCBI chr12:38,461,809...38,563,537
Ensembl chr12:38,461,830...38,564,306
JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:99,018,111...99,141,374
Ensembl chr14:99,025,005...99,129,100
JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3796786|PMID:18436203) MGI
Ensembl
PMID:18436203 GO_REF:0000107 MGI:3796786 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BDNF brain derived neurotrophic factor involved_in ISO (MGI:6295053|PMID:26708520) ARUK-UCL PMID:26708520 MGI:6295053 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765
JBrowse link
G BMF Bcl2 modifying factor acts_upstream_of_or_within ISO (MGI:2158578|PMID:11546872) MGI PMID:11546872 MGI:2158578 NCBI chr 1:131,178,021...131,199,668
Ensembl chr 1:131,178,315...131,200,393
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1932296|PMID:11290297) Ensembl
Ensembl
MGI
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chr10:52,586,089...52,596,154
Ensembl chr10:52,586,509...52,596,564
JBrowse link
G CDK11B cyclin-dependent kinase 11B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041915|PMID:15060143) Ensembl
Ensembl
MGI
PMID:15060143 GO_REF:0000107 MGI:3041915 NCBI chr 6:63,804,914...63,819,960 JBrowse link
G CTH cystathionine gamma-lyase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5304595|PMID:22244329) Ensembl
Ensembl
MGI
PMID:22244329 GO_REF:0000107 MGI:5304595 NCBI chr 6:142,454,922...142,486,352
Ensembl chr 6:142,454,914...142,486,367
JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4454604|PMID:20454446)
(MGI:3051737|PMID:15131783)
Ensembl
Ensembl
MGI
PMID:15131783 PMID:20454446 GO_REF:0000107 MGI:3051737 MGI:4454604 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in ISO (PMID:10869418) ARUK-UCL PMID:10869418 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:19,316,698...19,323,094 JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in ISO PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:4880811|PMID:21209208)
(PMID:21873635)
MGI
GO_Central
Ensembl
PMID:21209208 PMID:21873635 GO_REF:0000107 MGI:4880811 NCBI chr 5:15,779,329...15,813,029
Ensembl chr 5:15,779,334...15,812,543
JBrowse link
G GATA4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) BHF-UCL PMID:25590961 MGI:5780531 NCBI chr14:14,858,470...14,938,156
Ensembl chr14:14,884,662...14,939,941
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:25633408 RGD:13507311 NCBI chr13:32,705,326...32,733,804
Ensembl chr13:32,705,321...32,733,794
JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:25633408 RGD:13507311 NCBI chr 4:110,527,363...110,579,331
Ensembl chr 4:110,525,546...110,579,053
JBrowse link
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:682,823...686,144
Ensembl chr 4:682,835...686,116
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581090|PMID:15731106) MGI
Ensembl
PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr 3:10,038,074...10,039,441
Ensembl chr 3:10,037,949...10,039,704
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3688933|PMID:16857185) MGI PMID:16857185 MGI:3688933 NCBI chr11:7,733,874...7,759,528
Ensembl chr11:7,733,878...7,759,576
JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3056248|PMID:15499020) Ensembl
MGI
Ensembl
PMID:15499020 GO_REF:0000107 MGI:3056248 NCBI chr  X:56,173,773...56,206,121 JBrowse link
G ING2 inhibitor of growth family member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4867787|PMID:21124965) Ensembl
Ensembl
MGI
PMID:21124965 GO_REF:0000107 MGI:4867787 NCBI chr15:44,917,595...44,925,900
Ensembl chr15:44,918,066...44,925,867
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G LOC100513346 mitochondrial import inner membrane translocase subunit TIM16 acts_upstream_of_or_within ISO (MGI:4837988|PMID:20719856) MGI PMID:20719856 MGI:4837988 NCBI chr 3:37,928,098...38,005,619
Ensembl chr 3:37,928,096...37,985,151
JBrowse link
G MADD MAP kinase activating death domain acts_upstream_of_or_within ISO (MGI:3700423|PMID:14735464) MGI PMID:14735464 MGI:3700423 NCBI chr 2:15,270,783...15,315,459
Ensembl chr 2:15,270,789...15,315,477
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:120,575...131,060
Ensembl chr 5:120,580...130,939
JBrowse link
G MAZ MYC associated zinc finger protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,043,032...18,047,531
Ensembl chr 3:18,042,007...18,047,530
JBrowse link
G MEIS3 Meis homeobox 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4848231|PMID:21059917) Ensembl
Ensembl
MGI
PMID:21059917 GO_REF:0000107 MGI:4848231 NCBI chr 6:53,175,920...53,188,455
Ensembl chr 6:53,175,928...53,188,406
JBrowse link
G MNT MAX network transcriptional repressor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2675510|PMID:12970171) Ensembl
Ensembl
MGI
PMID:12970171 GO_REF:0000107 MGI:2675510 NCBI chr12:48,469,230...48,486,737
Ensembl chr12:48,469,239...48,486,729
JBrowse link
G MRTFA myocardin related transcription factor A acts_upstream_of_or_within ISO (MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:2183867 NCBI chr 5:7,751,350...7,975,927
Ensembl chr 5:7,959,312...7,972,574
JBrowse link
G NANOS3 nanos C2HC-type zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:65,274,849...65,278,689 JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3640733|PMID:16712836) Ensembl
Ensembl
MGI
PMID:16712836 GO_REF:0000107 MGI:3640733 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:63,487,051...63,506,249
Ensembl chr15:63,487,731...63,495,299
JBrowse link
G PCGF2 polycomb group ring finger 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1932296|PMID:11290297) Ensembl
Ensembl
MGI
PMID:11290297 GO_REF:0000107 MGI:1932296 NCBI chr12:23,362,631...23,375,779
Ensembl chr12:23,362,654...23,375,775
JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3044464|PMID:15148382) Ensembl
Ensembl
MGI
PMID:15148382 GO_REF:0000107 MGI:3044464 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251
JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:31,715,686...31,723,200
Ensembl chr13:31,715,689...31,723,197
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690
JBrowse link
G TMBIM1 transmembrane BAX inhibitor motif containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:120,348,740...120,365,055
Ensembl chr15:120,348,735...120,365,007
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936
JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31124343) ARUK-UCL
Ensembl
PMID:31124343 GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of_or_within ISO (MGI:4454604|PMID:20454446) MGI PMID:20454446 MGI:4454604 NCBI chr 6:80,110,238...80,138,165 JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL9 interleukin 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4367548|PMID:18551134) MGI
Ensembl
Ensembl
PMID:18551134 GO_REF:0000107 MGI:4367548 NCBI chr 2:138,048,943...138,052,588
Ensembl chr 2:138,048,943...138,052,588
JBrowse link
G IL9R interleukin 9 receptor acts_upstream_of_or_within ISO (MGI:4367548|PMID:18551134) MGI PMID:18551134 MGI:4367548 NCBI chr 3:41,581,253...41,590,485
Ensembl chr 3:41,583,693...41,594,867
JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
JBrowse link
G NLE1 notchless homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5468737|PMID:23231322) Ensembl
Ensembl
MGI
PMID:23231322 GO_REF:0000107 MGI:5468737 NCBI chr12:40,035,518...40,044,395
Ensembl chr12:40,035,547...40,044,397
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516
JBrowse link
G PIH1D1 PIH1 domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:54,524,172...54,529,700
Ensembl chr 6:54,524,172...54,535,249
JBrowse link
G PLAA phospholipase A2 activating protein involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:196,229,512...196,273,770
Ensembl chr 1:196,229,525...196,274,056
JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L1 BCL2 like 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G CREB3 cAMP responsive element binding protein 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:236,450,573...236,456,381
Ensembl chr 1:236,450,573...236,456,375
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 involved_in ISO PMID:15665855
(MGI:5616321|PMID:15665855)
ParkinsonsUK-UCL PMID:15665855 MGI:5616321 RGD:1558627 NCBI chr 2:16,186,206...16,220,948
Ensembl chr 2:16,186,206...16,220,940
JBrowse link
G FAU FAU ubiquitin like and ribosomal protein S30 fusion involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:7,070,903...7,072,811
Ensembl chr 2:7,070,906...7,072,809
JBrowse link
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5525071|PMID:22240901) Ensembl
MGI
Ensembl
PMID:22240901 GO_REF:0000107 MGI:5525071 NCBI chr 4:682,823...686,144
Ensembl chr 4:682,835...686,116
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:18,901,171...18,913,427
Ensembl chr 6:18,901,297...18,913,424
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) ParkinsonsUK-UCL PMID:23453807 MGI:5495588 NCBI chr  X:125,035,575...125,056,445
Ensembl chr  X:125,036,508...125,056,453
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4836774|PMID:20811152) Ensembl
Ensembl
MGI
PMID:20811152 GO_REF:0000107 MGI:4836774 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:52,017,100...52,086,747
Ensembl chr17:52,017,130...52,086,736
JBrowse link
G SELENOS selenoprotein S involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:139,829,002...139,836,923
Ensembl chr 1:139,828,791...139,836,914
JBrowse link
G SYVN1 synoviolin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3575050|PMID:15611074) Ensembl
Ensembl
MGI
PMID:15611074 GO_REF:0000107 MGI:3575050 NCBI chr 2:7,059,444...7,066,617
Ensembl chr 2:7,059,462...7,066,601
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5525071|PMID:22240901) Ensembl
Ensembl
MGI
PMID:22240901 GO_REF:0000107 MGI:5525071 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936
JBrowse link
G TXNDC12 thioredoxin domain containing 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18628206) MGI
Ensembl
Ensembl
PMID:18628206 GO_REF:0000107 NCBI chr 6:160,136,744...160,168,225
Ensembl chr 6:160,137,018...160,168,222
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) BHF-UCL PMID:16571599 MGI:3629256 NCBI chr 8:4,362,678...4,405,185
Ensembl chr 8:4,362,680...4,385,273
JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HYOU1 hypoxia up-regulated 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:46,264,929...46,277,056
Ensembl chr 9:46,264,933...46,276,995
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:64,749,478...64,891,653
Ensembl chr15:64,750,796...64,891,544
JBrowse link
G AR androgen receptor involved_in ISS
IEA
BHF-UCL
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:53,609,113...53,806,778
Ensembl chr  X:53,609,176...53,800,677
JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:107,012,967...107,269,370
Ensembl chr 3:107,012,986...107,269,477
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5486419|PMID:22675671) Ensembl
MGI
PMID:22675671 GO_REF:0000107 MGI:5486419 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,616...104,835,630
JBrowse link
G CTTN cortactin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5437589|PMID:22660580) Ensembl
Ensembl
MGI
PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813
JBrowse link
G DAB2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122
JBrowse link
G FCMR Fc mu receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:3576402 NCBI chr 9:67,530,944...67,546,441
Ensembl chr 9:67,532,083...67,546,402
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within ISO (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047441|PMID:15288121) Ensembl
Ensembl
MGI
PMID:15288121 GO_REF:0000107 MGI:3047441 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G HTT huntingtin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:1,809,768...1,934,002
Ensembl chr 8:1,809,785...1,934,024
JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:16942485)
PMID:17023532
BHF-UCL PMID:16942485 PMID:17023532 RGD:1600072 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IL19 interleukin 19 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5491082|PMID:23468852) Ensembl
Ensembl
MGI
PMID:23468852 GO_REF:0000107 MGI:5491082 NCBI chr 9:67,469,519...67,479,597
Ensembl chr 9:67,469,524...67,479,813
JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1340173|PMID:10429671)
GO_Central
GO_Central
MGI
PMID:10429671 PMID:21873635 MGI:1340173 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1340173|PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 MGI:1340173 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709
JBrowse link
G ITGA6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) BHF-UCL PMID:21310825 NCBI chr15:78,504,108...78,591,779
Ensembl chr15:78,504,078...78,591,777
JBrowse link
G ITGAV integrin subunit alpha V involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,851
JBrowse link
G LGALS3 galectin 3 involved_in IEA
IBA
(PMID:21873635) Ensembl
Ensembl
GO_Central
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:184,478,639...184,496,155
Ensembl chr 1:184,478,710...184,497,951
JBrowse link
G LMNA lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4879057|PMID:21151901) Ensembl
Ensembl
MGI
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 4:93,899,019...93,927,255
Ensembl chr 4:93,899,019...93,926,320
JBrowse link
G LOC100523672 heat shock factor protein 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:27,808,658...27,818,256
Ensembl chr 6:27,808,652...27,818,750
JBrowse link
G LOC100739508 glutathione S-transferase P-like involved_in ISO (PMID:16636664) BHF-UCL PMID:16636664 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G NRP1 neuropilin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:56,280,673...56,430,832
Ensembl chr10:56,280,665...56,430,777
JBrowse link
G PAK5 p21 (RAC1) activated kinase 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2673247|PMID:12897128) Ensembl
Ensembl
MGI
PMID:12897128 GO_REF:0000107 MGI:2673247 NCBI chr17:18,461,060...18,785,869
Ensembl chr17:18,461,062...18,785,313
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516
JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5546581|PMID:23950925)
(PMID:24113711)
MGI
Ensembl
Ensembl
PMID:23950925 PMID:24113711 GO_REF:0000107 MGI:5546581 NCBI chr 2:5,950,552...5,959,786
Ensembl chr 2:5,948,849...5,959,734
JBrowse link
G PHIP pleckstrin homology domain interacting protein acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17636024) MGI
Ensembl
Ensembl
PMID:17636024 GO_REF:0000107 NCBI chr 1:87,116,884...87,247,500
Ensembl chr 1:87,117,092...87,243,675
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within ISO (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009
JBrowse link
G PSME3 proteasome activator subunit 3 involved_in ISS
IEA
UniProt
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,028,112...20,035,865
Ensembl chr12:20,028,112...20,035,557
JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3689241|PMID:17015619) Ensembl
Ensembl
MGI
PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chr 4:77,593,204...77,649,551
Ensembl chr 4:77,594,324...77,649,548
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5304595|PMID:22244329) Ensembl
Ensembl
MGI
PMID:22244329 GO_REF:0000107 MGI:5304595 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5521568|PMID:22089168) MGI
Ensembl
PMID:22089168 GO_REF:0000107 MGI:5521568 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4456959|PMID:11493700) Ensembl
Ensembl
MGI
PMID:11493700 GO_REF:0000107 MGI:4456959 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376
JBrowse link
G SCG2 secretogranin II involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:125,420,773...125,426,303
Ensembl chr15:125,419,847...125,426,278
JBrowse link
G SGMS1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (MGI:3609513|PMID:16226406) MGI PMID:16226406 MGI:3609513 NCBI chr14:99,147,266...99,458,111
Ensembl chr14:99,147,272...99,185,082
JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:20,420,618...20,559,273
Ensembl chr14:20,420,618...20,559,271
JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:90,951,798...90,971,538
Ensembl chr13:90,949,021...90,971,411
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
JBrowse link
G TCF7L2 transcription factor 7 like 2 involved_in ISO PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528
JBrowse link
G TNFRSF4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) BHF-UCL PMID:11567634 MGI:2150820 NCBI chr 6:63,523,850...63,526,672
Ensembl chr 6:63,523,804...63,526,666
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096) BHF-UCL PMID:21828096 MGI:5287519 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3818355|PMID:17980593) Ensembl
Ensembl
MGI
PMID:17980593 GO_REF:0000107 MGI:3818355 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603
JBrowse link
G ZMYND11 zinc finger MYND-type containing 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:69,159,456...69,295,640
Ensembl chr10:69,159,455...69,295,306
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 5:23,015,777...23,035,943
Ensembl chr 5:23,017,176...23,033,517
JBrowse link
G BCL2L10 BCL2 like 10 acts_upstream_of_or_within ISO (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chr 1:119,594,004...119,607,709 JBrowse link
G COL2A1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1097047|PMID:9299161) Ensembl
Ensembl
MGI
PMID:9299161 GO_REF:0000107 MGI:1097047 NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718
JBrowse link
G CSF2 colony stimulating factor 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
JBrowse link
G CTNNA1 catenin alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5315030|PMID:22411810) Ensembl
Ensembl
MGI
PMID:22411810 GO_REF:0000107 MGI:5315030 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO (MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI PMID:18322241 PMID:18971423 MGI:3777228 MGI:3833195 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 acts_upstream_of_or_within ISO (MGI:3833195|PMID:18971423) MGI PMID:18971423 MGI:3833195 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link
G ENSA endosulfine alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,527,902...98,535,647
Ensembl chr 4:98,527,907...98,567,006
JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3577160|PMID:15817220)
GO_Central
Ensembl
GO_Central
MGI
PMID:15817220 PMID:21873635 GO_REF:0000107 MGI:3577160 NCBI chr 4:63,970,939...64,328,107
Ensembl chr 4:63,970,807...64,328,105
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:48,930,682...49,243,789
Ensembl chr17:48,966,814...49,243,739
JBrowse link
G EYA3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:85,095,409...85,185,856
Ensembl chr 6:85,095,409...85,185,799
JBrowse link
G EYA4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:30,260,784...30,575,593
Ensembl chr 1:30,261,917...30,533,604
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3690587|PMID:16956603) Ensembl
Ensembl
MGI
PMID:16956603 GO_REF:0000107 MGI:3690587 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 1:77,584,675...77,810,605
Ensembl chr 1:77,585,439...77,810,581
JBrowse link
G GAS1 growth arrest specific 1 acts_upstream_of_or_within ISO (MGI:5306314|PMID:15070677) MGI PMID:15070677 MGI:5306314 NCBI chr10:28,509,168...28,511,554
Ensembl chr10:28,509,261...28,510,301
JBrowse link
G GATA1 GATA binding protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:42,898,431...42,905,939
Ensembl chr  X:42,898,442...42,905,976
JBrowse link
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,936,602...22,965,929
Ensembl chr16:22,936,604...22,966,536
JBrowse link
G GFRAL GDNF family receptor alpha like acts_upstream_of_or_within ISO (MGI:3610244|PMID:16086688) MGI PMID:16086688 MGI:3610244 NCBI chr 7:25,749,608...25,806,844
Ensembl chr 7:25,750,184...25,808,637
JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:84,852,782...84,858,072
Ensembl chr 6:84,852,793...84,857,982
JBrowse link
G IL7 interleukin 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:84869|PMID:8950980) Ensembl
Ensembl
MGI
PMID:8950980 GO_REF:0000107 MGI:84869 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,288,544...158,329,898
Ensembl chr 1:158,288,544...158,329,881
JBrowse link
G LOC100521447 serine/threonine-protein kinase Sgk3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:67,899,247...68,073,092
Ensembl chr 4:67,899,261...68,031,457
JBrowse link
G LOC100524373 platelet factor 4 involved_in ISO (PMID:10666185) BHF-UCL PMID:10666185
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:10748004) BHF-UCL PMID:10748004
G MAP2K5 mitogen-activated protein kinase kinase 5 involved_in ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 1:165,458,263...165,733,452
Ensembl chr 1:165,458,258...165,740,297
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,144,136...60,158,739
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:98,562,092...98,567,014
Ensembl chr 4:98,534,812...98,567,006
JBrowse link
G NRG1 neuregulin 1 involved_in ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505
JBrowse link
G PRDX2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:86755|PMID:9115640) Ensembl
MGI
PMID:9115640 GO_REF:0000107 MGI:86755 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
JBrowse link
G SNAI2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (MGI:5142392|PMID:10518215) MGI PMID:10518215 MGI:5142392 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475
JBrowse link
G STRADB STE20 related adaptor beta involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2656105|PMID:12574163) Ensembl
Ensembl
MGI
PMID:12574163 GO_REF:0000107 MGI:2656105 NCBI chr15:105,055,218...105,083,429
Ensembl chr15:105,055,274...105,126,927
JBrowse link
G TERT telomerase reverse transcriptase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421
JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G UNC5B unc-5 netrin receptor B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:74,120,055...74,208,055
Ensembl chr14:74,120,050...74,205,263
JBrowse link
G ZC3HC1 zinc finger C3HC-type containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2670822|PMID:12748172) Ensembl
Ensembl
MGI
PMID:12748172 GO_REF:0000107 MGI:2670822 NCBI chr18:18,740,817...18,761,515
Ensembl chr18:18,740,845...18,761,718
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chr 4:94,026,391...94,082,206
Ensembl chr 4:94,026,386...94,080,420
JBrowse link
G BCL2L1 BCL2 like 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26582200) MGI
Ensembl
Ensembl
PMID:26582200 GO_REF:0000107 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668
JBrowse link
G CAPS calcyphosine acts_upstream_of_or_within ISO (MGI:2450205|PMID:12466268) MGI PMID:12466268 MGI:2450205 NCBI chr 2:73,122,784...73,124,979
Ensembl chr 2:73,123,191...73,124,916
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(PMID:26582200)
GO_Central
Ensembl
GO_Central
MGI
PMID:21873635 PMID:26582200 GO_REF:0000107 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,616...104,835,630
JBrowse link
G DAPK1 death associated protein kinase 1 acts_upstream_of_or_within ISO (MGI:2152512|PMID:11485996) MGI PMID:11485996 MGI:2152512 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202
JBrowse link
G FAIM Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1332875|PMID:10075978)
GO_Central
GO_Central
MGI
PMID:10075978 PMID:21873635 MGI:1332875 NCBI chr13:79,397,647...79,411,917
Ensembl chr13:79,397,931...79,411,905
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26582200) MGI
Ensembl
Ensembl
PMID:26582200 GO_REF:0000107 NCBI chr 5:15,779,329...15,813,029
Ensembl chr 5:15,779,334...15,812,543
JBrowse link
G FGA fibrinogen alpha chain involved_in ISO (PMID:10903502) BHF-UCL PMID:10903502 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202
JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409
JBrowse link
G FGG fibrinogen gamma chain involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688
JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569
JBrowse link
G HGF hepatocyte growth factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3054501|PMID:15314156) Ensembl
Ensembl
MGI
PMID:15314156 GO_REF:0000107 MGI:3054501 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564
JBrowse link
G HMGB2 high mobility group box 2 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3831045|PMID:19139395) AgBase
Ensembl
AgBase
MGI
PMID:19139395 GO_REF:0000024 GO_REF:0000107 MGI:3831045 NCBI chr14:16,709,966...16,712,288
Ensembl chr14:16,710,047...16,717,101
JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA
ISS
Ensembl
Ensembl
AgBase
AgBase
GO_REF:0000024 GO_REF:0000107
G ICAM1 intercellular adhesion molecule 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein involved_in
acts_upstream_of_or_within