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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptotic signaling pathway
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Accession:GO:0097190 term browser browse the term
Definition:The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Comment:This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Synonyms:exact_synonym: apoptotic signalling pathway;   induction of apoptosis by extracellular signals
 alt_id: GO:0008624



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apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of IMP (MGI:1860411|PMID:10845921) MGI PMID:10845921 MGI:1860411 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Anxa6 annexin A6 involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5485084|PMID:23341998)
GO_Central
CACAO
PMID:21873635 PMID:23341998 MGI:5485084 MGI:6201960 NCBI chr11:54,869,779...54,924,297
Ensembl chr11:54,869,934...54,924,271
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G AY074887 cDNA sequence AY074887 acts_upstream_of_or_within IDA (MGI:2663937|PMID:16963447) MGI PMID:16963447 MGI:2663937 NCBI chr 9:54,857,528...54,858,238
Ensembl chr 9:54,857,514...54,858,282
JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within IDA
IMP
(MGI:2158953|PMID:11717309), (MGI:3057092|PMID:15231831)
(MGI:2671672|PMID:12931191)
MGI PMID:11717309 PMID:12931191 PMID:15231831 MGI:2158953 MGI:2671672 MGI:3057092 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein acts_upstream_of_or_within
involved_in
IMP
IGI
ISO
(MGI:2676517|PMID:14507967), (MGI:2677915|PMID:12925707)
(MGI:3796786|PMID:18436203)
MGI PMID:12925707 PMID:14507967 PMID:18436203 GO_REF:0000096 MGI:2676517 MGI:2677915 MGI:3796786 MGI:4834177 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 involved_in
acts_upstream_of_or_within
ISO (MGI:2180967|PMID:11572983) MGI PMID:11572983 GO_REF:0000096 MGI:2180967 MGI:4834177 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene acts_upstream_of IGI (MGI:1932296|PMID:11290297) MGI PMID:11290297 MGI:1932296 NCBI chr 2:18,681,829...18,691,440
Ensembl chr 2:18,681,829...18,691,440
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II, beta acts_upstream_of IDA (MGI:3710042|PMID:17367784) MGI PMID:17367784 MGI:3710042 NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within IDA (MGI:2450211|PMID:12477715), (MGI:3603971|PMID:16183742) MGI PMID:12477715 PMID:16183742 MGI:2450211 MGI:3603971 NCBI chr 6:42,241,841...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
ISO
IDA
(MGI:3603971|PMID:16183742) MGI PMID:16183742 GO_REF:0000096 MGI:3603971 MGI:4834177 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G Cav1 caveolin 1, caveolae protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:17,306,287...17,341,327
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Cd24a CD24a antigen acts_upstream_of_or_within IDA (MGI:2686748|PMID:14707049), (MGI:3757615|PMID:8920854), (MGI:3757616|PMID:8943715) MGI PMID:8920854 PMID:8943715 PMID:14707049 MGI:2686748 MGI:3757615 MGI:3757616 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
JBrowse link
G Cd28 CD28 antigen acts_upstream_of_or_within IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide acts_upstream_of_or_within IDA (MGI:80946|PMID:8666928) MGI PMID:8666928 MGI:80946 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925
JBrowse link
G Cd5 CD5 antigen acts_upstream_of_or_within IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 acts_upstream_of IMP
IGI
(MGI:4454604|PMID:20454446)
(MGI:3051737|PMID:15131783)
MGI PMID:15131783 PMID:20454446 MGI:3051737 MGI:4454604 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Dap death-associated protein involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487
JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
JBrowse link
G Dapk3 death-associated protein kinase 3 acts_upstream_of_or_within IDA
IGI
(MGI:1196722|PMID:9488481)
(MGI:3687891|PMID:12917339)
MGI PMID:9488481 PMID:12917339 MGI:1196722 MGI:3687891 NCBI chr10:81,018,821...81,029,031
Ensembl chr10:81,018,839...81,029,031
JBrowse link
G Dapl1 death associated protein-like 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:59,314,997...59,335,364
Ensembl chr 2:59,314,997...59,335,364
JBrowse link
G Daxx Fas death domain-associated protein acts_upstream_of_or_within IGI (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
JBrowse link
G Dido1 death inducer-obliterator 1 acts_upstream_of_or_within IDA (MGI:1340704|PMID:10393935) MGI PMID:10393935 MGI:1340704 NCBI chr 2:180,299,756...180,351,886
Ensembl chr 2:180,299,757...180,351,792
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of IMP (MGI:4880811|PMID:21209208) MGI PMID:21209208 MGI:4880811 NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:65483|PMID:7511063), (MGI:80946|PMID:8666928) MGI
RGD
PMID:7511063 PMID:8666928 PMID:16953119 GO_REF:0000096 MGI:4417868 MGI:65483 MGI:80946 RGD:1600313 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:3525895|PMID:15629131), (MGI:65483|PMID:7511063) MGI PMID:7511063 PMID:15629131 GO_REF:0000096 MGI:3525895 MGI:4834177 MGI:65483 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:135,435,350...135,574,167
Ensembl chr 5:135,435,385...135,573,974
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498
JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:103,400,132...103,409,939
Ensembl chr12:103,408,426...103,409,939
JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:103,417,157...103,423,482
Ensembl chr12:103,417,157...103,423,482
JBrowse link
G Ifnz interferon zeta acts_upstream_of_or_within IDA (MGI:2448602|PMID:10835682) MGI PMID:10835682 MGI:2448602 NCBI chr 4:88,700,368...88,701,829
Ensembl chr 4:88,700,368...88,701,829
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of IGI (MGI:5287344|PMID:21750715) MGI PMID:21750715 MGI:5287344 NCBI chr11:70,579,187...70,593,177
Ensembl chr11:70,579,187...70,590,981
JBrowse link
G Ing5 inhibitor of growth family, member 5 acts_upstream_of IGI (MGI:5287344|PMID:21750715) MGI PMID:21750715 MGI:5287344 NCBI chr 1:93,731,648...93,749,823
Ensembl chr 1:93,731,687...93,749,823
JBrowse link
G Inhbb inhibin beta-B acts_upstream_of IGI (MGI:4454604|PMID:20454446) MGI PMID:20454446 MGI:4454604 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
JBrowse link
G Itgam integrin alpha M involved_in IDA (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of IMP
IGI
(MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of IGI (MGI:3619752|PMID:16458303) MGI PMID:16458303 MGI:3619752 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of IGI (MGI:3619752|PMID:16458303) MGI PMID:16458303 MGI:3619752 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 3:95,125,855...95,136,943
Ensembl chr 3:95,126,446...95,139,482
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of IMP
IGI
(MGI:3796786|PMID:18436203) MGI PMID:18436203 MGI:3796786 NCBI chr 8:84,900,359...84,911,396
Ensembl chr 8:84,900,360...84,911,846
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:70,346,813...70,355,208
Ensembl chr 8:70,346,830...70,355,208
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Pawr PRKC, apoptosis, WT1, regulator acts_upstream_of_or_within IGI (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of IGI (MGI:1932296|PMID:11290297) MGI PMID:11290297 MGI:1932296 NCBI chr11:97,579,647...97,593,260
Ensembl chr11:97,579,649...97,591,323
JBrowse link
G Pde3a phosphodiesterase 3A, cGMP inhibited involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:141,194,995...141,452,588
Ensembl chr 6:141,194,995...141,453,174
JBrowse link
G Pidd1 p53 induced death domain protein 1 acts_upstream_of_or_within IGI (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938
JBrowse link
G Ppard peroxisome proliferator activator receptor delta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:28,451,657...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Psen1 presenilin 1 acts_upstream_of IGI (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Psen2 presenilin 2 acts_upstream_of IGI (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:167,045,114...167,094,070
Ensembl chr 2:167,033,725...167,082,524
JBrowse link
G Senp1 SUMO1/sentrin specific peptidase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:97,936,625...97,991,625
Ensembl chr15:97,936,625...97,991,625
JBrowse link
G Sgpl1 sphingosine phosphate lyase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:60,934,421...60,983,463
Ensembl chr10:60,934,421...60,983,482
JBrowse link
G Shh sonic hedgehog involved_in IDA (MGI:5559673|PMID:11044396) Roslin_Institute PMID:11044396 MGI:5559673 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
G Slfn3 schlafen 3 involved_in ISO (PMID:31420216) UniProt PMID:31420216 NCBI chr11:83,082,156...83,105,980
Ensembl chr11:83,082,156...83,105,980
JBrowse link
G Spn sialophorin acts_upstream_of_or_within IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
G Tfpt TCF3 (E2A) fusion partner involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:3,623,323...3,632,928
Ensembl chr 7:3,623,323...3,632,928
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 acts_upstream_of_or_within IMP (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
G Tm2d1 TM2 domain containing 1 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:2135414|PMID:11278849)
GO_Central
MGI
PMID:11278849 PMID:21873635 MGI:2135414 MGI:6201960 NCBI chr 4:98,243,607...98,271,523
Ensembl chr 4:98,243,607...98,271,543
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within IDA (MGI:3525895|PMID:15629131), (MGI:67096|PMID:8208546) MGI PMID:8208546 PMID:15629131 MGI:3525895 MGI:67096 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein involved_in IDA (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 9:60,700,488...60,787,713
Ensembl chr 9:60,701,824...60,787,652
JBrowse link
G Umod uromodulin acts_upstream_of_or_within IMP (MGI:6107740|PMID:28990932) MGI PMID:28990932 MGI:6107740 NCBI chr 7:119,061,931...119,078,485
Ensembl chr 7:119,061,934...119,078,505
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor involved_in ISO RGD
MGI
PMID:9579411 GO_REF:0000096 MGI:4417868 RGD:70308 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 acts_upstream_of IGI (MGI:4454604|PMID:20454446) MGI PMID:20454446 MGI:4454604 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas (TNFRSF6)-associated via death domain involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 acts_upstream_of_or_within IMP (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
JBrowse link
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor, type 1B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bax BCL2-associated X protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within IMP (MGI:1343652|PMID:10476969) MGI PMID:10476969 MGI:1343652 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Casp3 caspase 3 involved_in IDA (MGI:4355273|PMID:19626005) ComplexPortal PMID:19626005 MGI:4355273 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 involved_in IC (MGI:6871006|PMID:19782763) ComplexPortal PMID:19782763 MGI:6871006 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
ISO
IGI
IMP
IDA
(MGI:5486419|PMID:22675671)
(MGI:6401035|PMID:31748744)
(MGI:5521568|PMID:22089168)
(MGI:2386520|PMID:12065591), (MGI:3687663|PMID:10588860)
MGI
UniProt
PMID:10588860 PMID:12065591 PMID:22089168 PMID:22675671 PMID:31748744 GO_REF:0000096 MGI:2386520 MGI:3687663 MGI:4834177 MGI:5486419 MGI:5521568 MGI:6401035 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cd27 CD27 antigen involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973
JBrowse link
G Cd70 CD70 antigen involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:57,452,997...57,456,777
Ensembl chr17:57,452,997...57,456,777
JBrowse link
G Cttn cortactin acts_upstream_of IGI (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr 7:143,989,461...144,024,743
Ensembl chr 7:143,989,470...144,024,746
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein acts_upstream_of IMP (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chr15:6,329,269...6,470,196
Ensembl chr15:6,329,269...6,470,193
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain involved_in
acts_upstream_of_or_within
ISO
IDA
IGI
(MGI:3687663|PMID:10588860)
(MGI:3603971|PMID:16183742)
MGI PMID:10588860 PMID:16183742 GO_REF:0000096 MGI:3603971 MGI:3687663 MGI:4834177 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) acts_upstream_of_or_within
involved_in
IMP
ISO
IDA
(MGI:2183141|PMID:12011074)
(MGI:3818355|PMID:17980593)
MGI PMID:12011074 PMID:17980593 GO_REF:0000096 MGI:2183141 MGI:3818355 MGI:4834177 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G G0s2 G0/G1 switch gene 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
JBrowse link
G Gsdma3 gasdermin A3 acts_upstream_of IDA (MGI:5446120|PMID:22585037) MGI PMID:22585037 MGI:5446120 NCBI chr11:98,517,175...98,529,627
Ensembl chr11:98,517,186...98,529,052
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IGI (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IGI (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:103,647,131...103,699,210
Ensembl chr 3:103,647,131...103,698,879
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:24970806) UniProt PMID:24970806 NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498
JBrowse link
G Ifng interferon gamma involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il12a interleukin 12a involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:68,597,977...68,605,883
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il33 interleukin 33 acts_upstream_of_or_within IGI (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 acts_upstream_of IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il7 interleukin 7 acts_upstream_of IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
JBrowse link
G Inhba inhibin beta-A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within IDA (MGI:5009182|PMID:12426001) MGI PMID:12426001 MGI:5009182 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within IMP (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within IMP (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:95,125,855...95,136,943
Ensembl chr 3:95,126,446...95,139,482
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 acts_upstream_of_or_within IDA (MGI:1930995|PMID:10924506) MGI PMID:10924506 MGI:1930995 NCBI chr 8:70,346,813...70,355,208
Ensembl chr 8:70,346,830...70,355,208
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 acts_upstream_of_or_within
involved_in
IMP
ISO
(MGI:3700102|PMID:17286969) MGI PMID:17286969 GO_REF:0000096 MGI:3700102 MGI:4417868 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Parp2 poly (ADP-ribose) polymerase family, member 2 acts_upstream_of_or_within IDA (MGI:2386520|PMID:12065591) MGI PMID:12065591 MGI:2386520 NCBI chr14:51,045,347...51,058,758
Ensembl chr14:51,045,298...51,058,758
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 acts_upstream_of IMP (MGI:3578073|PMID:15858817) MGI PMID:15858817 MGI:3578073 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:16207722) UniProt PMID:16207722 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898
JBrowse link
G Pidd1 p53 induced death domain protein 1 acts_upstream_of_or_within IGI (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938
JBrowse link
G Pml promyelocytic leukemia acts_upstream_of_or_within IMP (MGI:1306978|PMID:9806545) MGI PMID:9806545 MGI:1306978 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of IMP (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of IMP (MGI:80946|PMID:8666928) MGI PMID:8666928 MGI:80946 NCBI chr 1:137,990,597...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of IMP (MGI:3689241|PMID:17015619) MGI PMID:17015619 MGI:3689241 NCBI chr 1:6,284,858...6,346,599
Ensembl chr 1:6,276,421...6,346,872
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of IMP (MGI:3040721|PMID:14976225) MGI PMID:14976225 MGI:3040721 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within IDA (MGI:2386810|PMID:12235122) MGI PMID:12235122 MGI:2386810 NCBI chr12:75,761,022...75,782,503
Ensembl chr12:75,761,023...75,782,503
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr12:112,611,262...112,615,586
Ensembl chr12:112,611,113...112,615,583
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within
ISO
IGI
(MGI:5521568|PMID:22089168)
(MGI:5510543|PMID:19498109)
MGI PMID:19498109 PMID:22089168 GO_REF:0000096 MGI:4834177 MGI:5510543 MGI:5521568 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b involved_in ISO (PMID:21785459) UniProt PMID:21785459 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a acts_upstream_of_or_within IDA (MGI:2667292|PMID:12821115) MGI PMID:12821115 MGI:2667292 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:69721|PMID:7990930)
GO_Central
MGI
PMID:7990930 PMID:21873635 MGI:6201960 MGI:69721 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:2667292|PMID:12821115)
GO_Central
MGI
PMID:12821115 PMID:21873635 MGI:2667292 MGI:6201960 NCBI chr11:69,577,066...69,586,924
Ensembl chr11:69,577,076...69,586,675
JBrowse link
G Tradd TNFRSF1A-associated via death domain acts_upstream_of_or_within
involved_in
IGI
IBA
ISO
(MGI:5521568|PMID:22089168)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:22089168 GO_REF:0000096 MGI:4834177 MGI:5521568 MGI:6201960 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within IDA (MGI:3851310|PMID:19366691) MGI PMID:19366691 MGI:3851310 NCBI chr 8:115,166,377...116,079,451
Ensembl chr 8:115,166,395...116,079,447
JBrowse link
G Yap1 yes-associated protein 1 acts_upstream_of IGI (MGI:3818355|PMID:17980593) MGI PMID:17980593 MGI:3818355 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
G Zfp110 zinc finger protein 110 acts_upstream_of_or_within IMP (MGI:1929440|PMID:10545116) MGI PMID:10545116 MGI:1929440 NCBI chr 7:12,565,225...12,584,513
Ensembl chr 7:12,568,688...12,584,504
JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within IMP
IGI
IDA
(MGI:3032484|PMID:14967141)
(MGI:3029504|PMID:12431371)
(MGI:2183839|PMID:12115603), (MGI:2675215|PMID:12944463)
MGI PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 MGI:2183839 MGI:2675215 MGI:3029504 MGI:3032484 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bag3 BCL2-associated athanogene 3 acts_upstream_of_or_within IDA (MGI:3513163|PMID:11527400) MGI PMID:11527400 MGI:3513163 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in
acts_upstream_of_or_within
IBA
IGI
(MGI:6201960|PMID:21873635)
(MGI:3581932|PMID:15967824)
(MGI:3575206|PMID:15680329)
GO_Central
MGI
PMID:15680329 PMID:15967824 PMID:21873635 MGI:3575206 MGI:3581932 MGI:6201960 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein acts_upstream_of_or_within
involved_in
IGI
IBA
(MGI:3581932|PMID:15967824)
(MGI:6201960|PMID:21873635)
(MGI:3575206|PMID:15680329)
MGI
GO_Central
PMID:15680329 PMID:15967824 PMID:21873635 MGI:3575206 MGI:3581932 MGI:6201960 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 involved_in
acts_upstream_of_or_within
IBA
IGI
(MGI:6201960|PMID:21873635)
(MGI:2179928|PMID:12082633)
GO_Central
MGI
PMID:12082633 PMID:21873635 MGI:2179928 MGI:6201960 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Bcl2a1c B cell leukemia/lymphoma 2 related protein A1c involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:114,159,203...114,159,646
Ensembl chr 9:114,159,203...114,159,646
JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967
JBrowse link
G Bcl2l1 BCL2-like 1 acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:2183839|PMID:12115603)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:12115603 PMID:21873635 MGI:2183839 MGI:6201960 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in
acts_upstream_of
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1326939|PMID:9878060)
GO_Central
MGI
PMID:9878060 PMID:21873635 MGI:1326939 MGI:6201960 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) acts_upstream_of_or_within IMP
IGI
(MGI:3581932|PMID:15967824) MGI PMID:15967824 MGI:3581932 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bcl2l2 BCL2-like 2 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:2183839|PMID:12115603)
GO_Central
MGI
PMID:12115603 PMID:21873635 MGI:2183839 MGI:6201960 NCBI chr14:55,120,804...55,136,384
Ensembl chr14:55,120,834...55,125,691
Ensembl chr14:55,120,834...55,125,691
JBrowse link
G Bok BCL2-related ovarian killer involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:3691999|PMID:11536012)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:11536012 PMID:21873635 MGI:3691999 MGI:6201960 NCBI chr 6:42,241,841...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Clca3a2 chloride channel accessory 3A2 acts_upstream_of_or_within IDA (MGI:2152633|PMID:11483609) MGI PMID:11483609 MGI:2152633 NCBI chr 3:144,486,340...144,525,385
Ensembl chr 3:144,502,320...144,525,255
JBrowse link
G Col2a1 collagen, type II, alpha 1 acts_upstream_of IMP (MGI:1097047|PMID:9299161) MGI PMID:9299161 MGI:1097047 NCBI chr15:97,873,483...97,902,722
Ensembl chr15:97,873,483...97,902,576
JBrowse link
G Ctnna1 catenin (cadherin associated protein), alpha 1 acts_upstream_of IMP (MGI:5315030|PMID:22411810) MGI PMID:22411810 MGI:5315030 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 acts_upstream_of IDA (MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI PMID:18322241 PMID:18971423 MGI:3777228 MGI:3833195 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of IMP (MGI:3577160|PMID:15817220) MGI PMID:15817220 MGI:3577160 NCBI chr 1:14,239,177...14,381,259
Ensembl chr 1:14,239,178...14,380,459
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within IDA (MGI:2158099|PMID:11700312) MGI PMID:11700312 MGI:2158099 NCBI chr 2:165,436,892...165,613,647
Ensembl chr 2:165,436,952...165,613,647
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain acts_upstream_of_or_within IMP (MGI:2675560|PMID:13679421) MGI PMID:13679421 MGI:2675560 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:2675560|PMID:13679421)
GO_Central
MGI
PMID:13679421 PMID:21873635 MGI:2675560 MGI:6201960 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of IMP (MGI:3690587|PMID:16956603) MGI PMID:16956603 MGI:3690587 NCBI chr13:118,851,235...118,929,109
Ensembl chr13:118,806,327...118,928,651
JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within IGI (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:5514334|PMID:16543145)
GO_Central
UniProt
PMID:16543145 PMID:21873635 MGI:5514334 MGI:6201960 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:5514334|PMID:16543145)
GO_Central
UniProt
PMID:16543145 PMID:21873635 MGI:5514334 MGI:6201960 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within IDA (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of_or_within IMP (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within IMP (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within IDA (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within IDA (MGI:2387238|PMID:12124386), (MGI:2675215|PMID:12944463), (MGI:3032484|PMID:14967141), (MGI:3057092|PMID:15231831), (MGI:3513163|PMID:11527400), (MGI:3575206|PMID:15680329) MGI PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 More... MGI:2387238 MGI:2675215 MGI:3032484 MGI:3057092 MGI:3513163 MGI:3575206 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:2183839|PMID:12115603)
GO_Central
MGI
PMID:12115603 PMID:21873635 MGI:2183839 MGI:6201960 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Itgav integrin alpha V involved_in IDA (MGI:3530680|PMID:15591537) BHF-UCL PMID:15591537 MGI:3530680 NCBI chr 2:83,551,625...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Itm2b integral membrane protein 2B acts_upstream_of_or_within IGI
IDA
(MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr14:73,599,666...73,622,729
Ensembl chr14:73,599,666...73,622,729
JBrowse link
G Kitl kit ligand acts_upstream_of_or_within IDA (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
JBrowse link
G Lcn2 lipocalin 2 acts_upstream_of_or_within IDA (MGI:4821076|PMID:16377569) MGI PMID:16377569 MGI:4821076 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 involved_in IMP
IBA
ISO
(MGI:5514334|PMID:16543145)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
MGI
PMID:16543145 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5514334 MGI:6201960 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mknk1 MAP kinase-interacting serine/threonine kinase 1 acts_upstream_of_or_within IMP
IGI
(MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chr 4:115,695,140...115,736,453
Ensembl chr 4:115,696,395...115,736,447
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 acts_upstream_of_or_within IMP
IGI
(MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of IMP (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within IDA (MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:2681362 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of IDA (MGI:67124|PMID:8206089) MGI PMID:8206089 MGI:67124 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tnfrsf23 tumor necrosis factor receptor superfamily, member 23 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:143,219,544...143,239,836
Ensembl chr 7:143,219,546...143,239,609
JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within IMP (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bag3 BCL2-associated athanogene 3 acts_upstream_of_or_within ISO (MGI:1349210|PMID:10597216) MGI PMID:10597216 MGI:1349210 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
JBrowse link
G Bax BCL2-associated X protein acts_upstream_of_or_within IDA (MGI:1349210|PMID:10597216) MGI PMID:10597216 MGI:1349210 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within ISO (MGI:1349210|PMID:10597216) MGI PMID:10597216 MGI:1349210 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l10 Bcl2-like 10 NOT|acts_upstream_of_or_within ISO (MGI:2153322|PMID:11689480) MGI PMID:11689480 MGI:2153322 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
JBrowse link
G Bex3 brain expressed X-linked 3 acts_upstream_of_or_within IPI (MGI:1859527|PMID:10764727) MGI PMID:10764727 MGI:1859527 NCBI chr  X:135,171,002...135,172,727
Ensembl chr  X:135,171,002...135,172,727
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
ISS
(MGI:5514134|PMID:18188704) MGI
UniProt
PMID:18188704 GO_REF:0000096 MGI:4834177 MGI:5514134 NCBI chr19:44,127,685...44,134,909
Ensembl chr19:44,127,685...44,134,885
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
IBA
IMP
IC
ISO
(MGI:6201960|PMID:21873635)
(MGI:3054336|PMID:15322156)
(MGI:4947444|PMID:21368762)
GO_Central
MGI
ComplexPortal
PMID:15322156 PMID:21368762 PMID:21873635 GO_REF:0000096 MGI:3054336 MGI:4834177 MGI:4947444 MGI:6201960 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within
ISO
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1347587|PMID:10235259)
MGI
GO_Central
PMID:10235259 PMID:21873635 GO_REF:0000096 MGI:1347587 MGI:4834177 MGI:6201960 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G D1Pas1 DNA segment, Chr 1, Pasteur Institute 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:186,699,613...186,702,824
Ensembl chr 1:186,699,613...186,702,824
JBrowse link
G Dab2ip disabled 2 interacting protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006
JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within IGI
IMP
(MGI:4431305|PMID:20053891)
(MGI:3051747|PMID:15010850)
MGI PMID:15010850 PMID:20053891 MGI:3051747 MGI:4431305 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
JBrowse link
G Daxx Fas death domain-associated protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:13,147,261...13,160,222
Ensembl chr  X:13,147,209...13,160,291
JBrowse link
G Ddx47 DEAD box helicase 47 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:134,988,575...135,000,739
Ensembl chr 6:134,988,575...135,000,739
JBrowse link
G Dedd death effector domain-containing involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1306907|PMID:9774341)
GO_Central
MGI
PMID:9774341 PMID:21873635 MGI:1306907 MGI:6201960 NCBI chr 1:171,152,229...171,170,069
Ensembl chr 1:171,156,713...171,169,899
JBrowse link
G Dedd2 death effector domain-containing DNA binding protein 2 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:24,899,337...24,920,035
Ensembl chr 7:24,899,340...24,920,040
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr18:38,383,302...38,395,682
Ensembl chr18:38,383,308...38,398,514
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) acts_upstream_of_or_within
involved_in
IDA
IGI
IMP
(MGI:2687085|PMID:12801066), (MGI:3038547|PMID:15039234), (MGI:3576402|PMID:15632112), (MGI:3687663|PMID:10588860), (MGI:3819026|PMID:18363966), (MGI:77677|PMID:8524870)
(MGI:3029504|PMID:12431371)
(MGI:1340173|PMID:10429671)
(MGI:2687085|PMID:12801066), (MGI:3029504|PMID:12431371), (MGI:77677|PMID:8524870)
(MGI:5009197|PMID:10950869)
MGI
BHF-UCL
PMID:8524870 PMID:10429671 PMID:10588860 PMID:10950869 PMID:12431371 More... MGI:1340173 MGI:2687085 MGI:3029504 MGI:3038547 MGI:3576402 MGI:3687663 MGI:3819026 MGI:5009197 MGI:77677 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(MGI:3038547|PMID:15039234), (MGI:3687663|PMID:10588860)
(MGI:6201960|PMID:21873635)
(MGI:5755333|PMID:26582200)
MGI
RGD
GO_Central
PMID:10588860 PMID:15039234 PMID:16689665 PMID:21873635 PMID:26582200 GO_REF:0000096 MGI:3038547 MGI:3687663 MGI:4417868 MGI:4834177 MGI:5755333 MGI:6201960 RGD:1582444 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Gabarap gamma-aminobutyric acid receptor associated protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:69,882,196...69,885,775
Ensembl chr11:69,881,969...69,885,777
JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of IMP (MGI:3831045|PMID:19139395) MGI PMID:19139395 MGI:3831045 NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033
JBrowse link
G Il18 interleukin 18 involved_in TAS (MGI:3688022|PMID:11714750) UniProt PMID:11714750 MGI:3688022 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Itprip inositol 1,4,5-triphosphate receptor interacting protein acts_upstream_of IGI (MGI:4431305|PMID:20053891) MGI PMID:20053891 MGI:4431305 NCBI chr19:47,883,029...47,907,762
Ensembl chr19:47,883,041...47,907,738
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within IMP
IGI
(MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Ngf nerve growth factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Pidd1 p53 induced death domain protein 1 acts_upstream_of_or_within IGI (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within IGI
IMP
(MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 acts_upstream_of IGI
IMP
(MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within IGI (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824
JBrowse link
G Skil SKI-like acts_upstream_of IMP (MGI:1858539|PMID:10811619) MGI PMID:10811619 MGI:1858539 NCBI chr 3:31,149,122...31,177,072
Ensembl chr 3:31,149,207...31,176,726
JBrowse link
G Sort1 sortilin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of IGI (MGI:4420852|PMID:20080598) MGI PMID:20080598 MGI:4420852 NCBI chr15:34,875,645...35,155,990
Ensembl chr15:34,875,642...35,179,067
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of IGI (MGI:4420852|PMID:20080598) MGI PMID:20080598 MGI:4420852 NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in
IGI
IBA
ISO
(MGI:3029504|PMID:12431371)
(MGI:4420852|PMID:20080598)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:12431371 PMID:20080598 PMID:21873635 GO_REF:0000096 MGI:3029504 MGI:4420852 MGI:4834177 MGI:6201960 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b involved_in ISO RGD
MGI
PMID:19934367 GO_REF:0000096 MGI:4417868 RGD:4142856 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube4b ubiquitination factor E4B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:149,412,873...149,512,618
Ensembl chr 4:149,412,873...149,511,206
JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone involved_in ISO RGD
MGI
PMID:11790788 GO_REF:0000096 MGI:4417868 RGD:1358682 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Esr2 estrogen receptor 2 (beta) acts_upstream_of_or_within IMP (MGI:3047056|PMID:15187231) MGI PMID:15187231 MGI:3047056 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Mettl21c methyltransferase like 21C acts_upstream_of_or_within IMP (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chr 1:44,048,559...44,081,745
Ensembl chr 1:44,048,568...44,059,194
JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 involved_in IC (MGI:6867323|PMID:10206961) ComplexPortal PMID:10206961 MGI:6867323 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bax BCL2-associated X protein involved_in
acts_upstream_of
ISO
IMP
(MGI:3692043|PMID:14502238) MGI PMID:14502238 GO_REF:0000096 MGI:3692043 MGI:4834177 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of IDA (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 acts_upstream_of_or_within IMP
IGI
(MGI:3696331|PMID:16954213) MGI PMID:16954213 MGI:3696331 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase acts_upstream_of IMP (MGI:3790365|PMID:17938250) MGI PMID:17938250 MGI:3790365 NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785
JBrowse link
G Casp12 caspase 12 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 involved_in IC (MGI:6871005|PMID:12031984) ComplexPortal PMID:12031984 MGI:6871005 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase involved_in ISO (PMID:15123740) ParkinsonsUK-UCL PMID:15123740 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp7 caspase 7 involved_in IC (MGI:6871006|PMID:19782763) ComplexPortal PMID:19782763 MGI:6871006 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp9 caspase 9 involved_in IC (MGI:6867323|PMID:10206961) ComplexPortal PMID:10206961 MGI:6867323 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Clu clusterin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Coa8 cytochrome c oxidase assembly factor 8 acts_upstream_of_or_within IDA (MGI:3694393|PMID:16782708) MGI PMID:16782708 MGI:3694393 NCBI chr12:111,679,394...111,721,491
Ensembl chr12:111,679,695...111,721,487
JBrowse link
G Cycs cytochrome c, somatic involved_in IC (MGI:6867323|PMID:10206961) ComplexPortal PMID:10206961 MGI:6867323 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G D1Pas1 DNA segment, Chr 1, Pasteur Institute 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:186,699,613...186,702,824
Ensembl chr 1:186,699,613...186,702,824
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:13,147,261...13,160,222
Ensembl chr  X:13,147,209...13,160,291
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in TAS (MGI:5306292|PMID:18309324) UniProt PMID:18309324 MGI:5306292 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
JBrowse link
G Eaf2 ELL associated factor 2 acts_upstream_of_or_within ISO (MGI:2673555|PMID:12907652) MGI PMID:12907652 MGI:2673555 NCBI chr16:36,613,246...36,695,275
Ensembl chr16:36,613,246...36,695,365
JBrowse link
G Flcn folliculin acts_upstream_of IMP (MGI:5050037|PMID:21258407) MGI PMID:21258407 MGI:5050037 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842
JBrowse link
G Hras Harvey rat sarcoma virus oncogene acts_upstream_of_or_within IMP
IGI
(MGI:3696331|PMID:16954213) MGI PMID:16954213 MGI:3696331 NCBI chr 7:140,769,847...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Htra2 HtrA serine peptidase 2 acts_upstream_of_or_within IMP (MGI:3511636|PMID:15509788) MGI PMID:15509788 MGI:3511636 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254
JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B involved_in IMP (MGI:5433833|PMID:21151029) UniProt PMID:21151029 MGI:5433833 NCBI chr12:103,417,157...103,423,482
Ensembl chr12:103,417,157...103,423,482
JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of IMP (MGI:4819697|PMID:15485691) MGI PMID:15485691 MGI:4819697 NCBI chr 1:151,220,237...151,240,196
Ensembl chr 1:151,220,228...151,240,173
JBrowse link
G Lgals12 lectin, galactose binding, soluble 12 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2159491|PMID:11435439)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:11435439 PMID:21873635 MGI:2159491 MGI:6201960 NCBI chr19:7,574,021...7,584,601
Ensembl chr19:7,574,025...7,584,558
JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:95,125,855...95,136,943
Ensembl chr 3:95,126,446...95,139,482
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within IMP (MGI:2677657|PMID:14632208) MGI PMID:14632208 MGI:2677657 NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
JBrowse link
G Nbn nibrin acts_upstream_of_or_within IMP (MGI:3805397|PMID:18614044) MGI PMID:18614044 MGI:3805397 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) involved_in IMP (MGI:5573029|PMID:24312627) UniProt PMID:24312627 MGI:5573029 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in IDA (MGI:5315351|PMID:15863367) UniProt PMID:15863367 MGI:5315351 NCBI chr 9:92,132,243...92,154,614
Ensembl chr 9:92,131,803...92,154,331
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Ppm1f protein phosphatase 1F (PP2C domain containing) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:16,714,314...16,745,239
Ensembl chr16:16,714,333...16,745,228
JBrowse link
G Prkca protein kinase C, alpha acts_upstream_of_or_within IMP (MGI:2671671|PMID:12928424) MGI PMID:12928424 MGI:2671671 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within IDA (MGI:1932564|PMID:10859351) MGI PMID:10859351 MGI:1932564 NCBI chr12:75,761,022...75,782,503
Ensembl chr12:75,761,023...75,782,503
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23313858) AgBase PMID:23313858 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in
NOT|involved_in
ISO (PMID:12011449) BHF-UCL PMID:12011449 NCBI chr12:112,611,262...112,615,586
Ensembl chr12:112,611,113...112,615,583
JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein acts_upstream_of_or_within IMP (MGI:1344924|PMID:10479688) MGI PMID:10479688 MGI:1344924 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 acts_upstream_of_or_within ISO (MGI:2178768|PMID:11463391) MGI PMID:11463391 MGI:2178768 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bok BCL2-related ovarian killer involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486
JBrowse link
G Casp6 caspase 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of IGI (MGI:5662131|PMID:26158450) MGI PMID:26158450 MGI:5662131 NCBI chr 9:102,463,777...102,503,767
Ensembl chr 9:102,461,787...102,503,733
JBrowse link
G Ddx5 DEAD box helicase 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011
JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within IDA (MGI:1927703|PMID:11095619) MGI PMID:11095619 MGI:1927703 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G E2f2 E2F transcription factor 2 acts_upstream_of_or_within IDA (MGI:1927703|PMID:11095619) MGI PMID:11095619 MGI:1927703 NCBI chr 4:135,899,585...135,923,368
Ensembl chr 4:135,899,705...135,923,368
JBrowse link
G Eda2r ectodysplasin A2 receptor acts_upstream_of_or_within IGI (MGI:4454200|PMID:20434500) MGI PMID:20434500 MGI:4454200 NCBI chr  X:96,377,447...96,420,815
Ensembl chr  X:96,377,446...96,420,822
JBrowse link
G Fhit fragile histidine triad gene involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr14:11,307,679...12,919,681
Ensembl chr14:11,307,738...12,919,681
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:54,757,209...54,761,332
Ensembl chr11:54,757,209...54,761,327
JBrowse link
G Ifi203 interferon activated gene 203 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,747,966...173,770,432
Ensembl chr 1:173,747,973...173,770,238
JBrowse link
G Ifi204 interferon activated gene 204 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509
JBrowse link
G Ifi205 interferon activated gene 205 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,839,549...173,859,617
Ensembl chr 1:173,839,564...173,859,376
JBrowse link
G Ifi206 interferon activated gene 206 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,296,051...173,318,884
Ensembl chr 1:173,296,051...173,318,607
JBrowse link
G Ifi207 interferon activated gene 207 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,550,993...173,569,394
Ensembl chr 1:173,550,993...173,569,313
JBrowse link
G Ifi208 interferon activated gene 208 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,501,194...173,525,959
Ensembl chr 1:173,501,241...173,525,961
JBrowse link
G Ifi209 interferon activated gene 209 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,458,425...173,475,494
Ensembl chr 1:173,458,483...173,475,494
JBrowse link
G Ifi211 interferon activated gene 211 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612
JBrowse link
G Ifi213 interferon activated gene 213 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,393,849...173,426,868
Ensembl chr 1:173,393,849...173,426,840
JBrowse link
G Ifi214 interferon activated gene 214 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,348,877...173,363,523
Ensembl chr 1:173,347,283...173,363,523
JBrowse link
G Jmy junction-mediating and regulatory protein involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1891484|PMID:10518217)
GO_Central
MGI
PMID:10518217 PMID:21873635 MGI:1891484 MGI:6201960 NCBI chr13:93,566,605...93,636,316
Ensembl chr13:93,566,609...93,636,316
JBrowse link
G Mndal myeloid nuclear differentiation antigen like involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:173,684,786...173,708,035
Ensembl chr 1:173,676,692...173,708,447
JBrowse link
G Mybbp1a MYB binding protein (P160) 1a involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:72,332,153...72,342,596
Ensembl chr11:72,332,181...72,342,594
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:94,917,084...94,932,197
Ensembl chr11:94,917,084...94,932,180
JBrowse link
G Perp PERP, TP53 apoptosis effector acts_upstream_of_or_within IDA (MGI:1929912|PMID:10733530) MGI PMID:10733530 MGI:1929912 NCBI chr10:18,720,819...18,732,821
Ensembl chr10:18,720,768...18,732,821
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in IMP
ISO
(MGI:2679929|PMID:14500851) UniProt
MGI
PMID:14500851 GO_REF:0000096 MGI:2679929 MGI:4834177 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pml promyelocytic leukemia acts_upstream_of_or_within IMP (MGI:3034149|PMID:14992722) MGI PMID:14992722 MGI:3034149 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Pou4f1 POU domain, class 4, transcription factor 1 involved_in IMP (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr14:104,699,111...104,705,554
Ensembl chr14:104,699,112...104,705,435
JBrowse link
G Pou4f2 POU domain, class 4, transcription factor 2 involved_in IMP (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr 8:79,159,638...79,163,276
Ensembl chr 8:79,159,639...79,163,274
JBrowse link
G Ppp1r13b protein phosphatase 1, regulatory subunit 13B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:111,794,892...111,874,549
Ensembl chr12:111,794,891...111,874,544
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V NOT|acts_upstream_of_or_within IGI (MGI:3589512|PMID:16107883) MGI PMID:16107883 MGI:3589512 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) acts_upstream_of IMP (MGI:3583493|PMID:15989966) MGI PMID:15989966 MGI:3583493 NCBI chr16:13,598,563...13,632,705
Ensembl chr16:13,598,572...13,632,703
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:105,380,937...105,386,592
Ensembl chr 7:105,380,937...105,386,592
JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within IMP (MGI:2183272|PMID:12135983) MGI PMID:12135983 MGI:2183272 NCBI chr 9:108,867,635...108,886,860
Ensembl chr 9:108,867,633...108,886,845
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within
involved_in
IDA
ISO
IGI
(MGI:2183272|PMID:12135983), (MGI:3589512|PMID:16107883)
(MGI:5883206|PMID:22262176)
(MGI:4454200|PMID:20434500)
MGI
CAFA
PMID:12135983 PMID:16107883 PMID:20434500 PMID:22262176 GO_REF:0000096 MGI:2183272 MGI:3589512 MGI:4454200 MGI:4834177 MGI:5883206 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53bp2 transformation related protein 53 binding protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:182,236,732...182,290,001
Ensembl chr 1:182,236,737...182,289,997
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within IGI (MGI:1930321|PMID:11058590) MGI PMID:11058590 MGI:1930321 NCBI chr 8:115,166,377...116,079,451
Ensembl chr 8:115,166,395...116,079,447
JBrowse link
G Zfp385b zinc finger protein 385B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:77,240,966...77,648,050
Ensembl chr 2:77,240,978...77,649,983
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IGI (MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:3584078 NCBI chr11:79,980,205...80,026,623
Ensembl chr11:79,980,226...80,026,620
JBrowse link
G Atm ataxia telangiectasia mutated acts_upstream_of_or_within
involved_in
IMP
IBA
IGI
(MGI:1926715|PMID:11040211), (MGI:3652689|PMID:16777961)
(MGI:6201960|PMID:21873635)
(MGI:3714678|PMID:17476307)
MGI
GO_Central
PMID:11040211 PMID:16777961 PMID:17476307 PMID:21873635 MGI:1926715 MGI:3652689 MGI:3714678 MGI:6201960 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within IMP
IDA
(MGI:3029504|PMID:12431371)
(MGI:3057092|PMID:15231831)
MGI PMID:12431371 PMID:15231831 MGI:3029504 MGI:3057092 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within
involved_in
IGI
IBA
IMP
(MGI:3689797|PMID:15901672)
(MGI:6201960|PMID:21873635)
(MGI:3581932|PMID:15967824)
MGI
GO_Central
PMID:15901672 PMID:15967824 PMID:21873635 MGI:3581932 MGI:3689797 MGI:6201960 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein acts_upstream_of_or_within
involved_in
IMP
IBA
IGI
(MGI:2675761|PMID:12952892)
(MGI:6201960|PMID:21873635)
(MGI:3581932|PMID:15967824)
(MGI:3689797|PMID:15901672)
MGI
GO_Central
PMID:12952892 PMID:15901672 PMID:15967824 PMID:21873635 MGI:2675761 MGI:3581932 MGI:3689797 MGI:6201960 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within
involved_in
IGI
IBA
(MGI:3584078|PMID:15983387)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15983387 PMID:21873635 MGI:3584078 MGI:6201960 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Bcl2a1c B cell leukemia/lymphoma 2 related protein A1c involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:114,159,203...114,159,646
Ensembl chr 9:114,159,203...114,159,646
JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967
JBrowse link
G Bcl2l1 BCL2-like 1 acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:2677658|PMID:14517295)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:14517295 PMID:21873635 MGI:2677658 MGI:6201960 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) acts_upstream_of_or_within ISO
IGI
(MGI:2158578|PMID:11546872)
(MGI:3581932|PMID:15967824)
MGI PMID:11546872 PMID:15967824 MGI:2158578 MGI:3581932 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bcl2l2 BCL2-like 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr14:55,120,804...55,136,384
Ensembl chr14:55,120,834...55,125,691
Ensembl chr14:55,120,834...55,125,691
JBrowse link
G Bok BCL2-related ovarian killer involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486
JBrowse link
G Brca1 breast cancer 1, early onset acts_upstream_of_or_within ISO (MGI:2682549|PMID:14654789) MGI PMID:14654789 MGI:2682549 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
JBrowse link
G Brca2 breast cancer 2, early onset acts_upstream_of_or_within IGI (MGI:3714678|PMID:17476307) MGI PMID:17476307 MGI:3714678 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
JBrowse link
G Casp2 caspase 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:42,241,841...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp9 caspase 9 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Crip1 cysteine-rich protein 1 (intestinal) involved_in ISO
IBA
ISS
(MGI:6201960|PMID:21873635)
(MGI:5315680|PMID:20415737)
MGI
GO_Central
UniProt
PMID:20415737 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5315680 MGI:6201960 NCBI chr12:113,115,632...113,117,499
Ensembl chr12:113,109,936...113,117,499
JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Ei24 etoposide induced 2.4 mRNA acts_upstream_of_or_within IDA (MGI:1350723|PMID:10594026) MGI PMID:10594026 MGI:1350723 NCBI chr 9:36,690,449...36,708,630
Ensembl chr 9:36,690,455...36,708,689
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695
JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 acts_upstream_of_or_within IMP (MGI:1913261|PMID:11005836) MGI PMID:11005836 MGI:1913261 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947
JBrowse link
G Fnip2 folliculin interacting protein 2 involved_in IMP (MGI:5284752|PMID:19137017) UniProt PMID:19137017 MGI:5284752 NCBI chr 3:79,363,278...79,475,458
Ensembl chr 3:79,363,281...79,475,103
JBrowse link
G Hic1 hypermethylated in cancer 1 involved_in IDA
ISO
(MGI:5297787|PMID:16269335) UniProt
MGI
PMID:16269335 GO_REF:0000096 MGI:4834177 MGI:5297787 NCBI chr11:75,052,203...75,061,081
Ensembl chr11:75,055,391...75,060,345
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO RGD
MGI
PMID:11854317 GO_REF:0000096 MGI:4417868 RGD:625692 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within IDA (MGI:3775338|PMID:11753682) MGI PMID:11753682 MGI:3775338 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344
JBrowse link
G Mael maelstrom spermatogenic transposon silencer acts_upstream_of_or_within IMP (MGI:3813746|PMID:18694567) MGI PMID:18694567 MGI:3813746 NCBI chr 1:166,028,954...166,066,313
Ensembl chr 1:166,028,770...166,066,316
JBrowse link
G Mbd4 methyl-CpG binding domain protein 4 acts_upstream_of_or_within IMP (MGI:2678630|PMID:14562041) MGI PMID:14562041 MGI:2678630 NCBI chr 6:115,817,658...115,830,361
Ensembl chr 6:115,817,658...115,830,332
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 acts_upstream_of_or_within
involved_in
IDA
IBA
(MGI:3689797|PMID:15901672)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15901672 PMID:21873635 MGI:3689797 MGI:6201960 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within IMP (MGI:2678630|PMID:14562041) MGI PMID:14562041 MGI:2678630 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within IMP (MGI:3029112|PMID:14744764)
(MGI:1334080|PMID:10097137)
MGI PMID:10097137 PMID:14744764 MGI:1334080 MGI:3029112 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within IMP (MGI:3053495|PMID:15324697) MGI PMID:15324697 MGI:3053495 NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
JBrowse link
G Myc myelocytomatosis oncogene acts_upstream_of_or_within IMP
IDA
(MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 acts_upstream_of_or_within IGI
IMP
(MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr14:56,062,252...56,071,400
Ensembl chr14:56,060,601...56,071,400
JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within IGI
IMP
(MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within IMP (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pml promyelocytic leukemia acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
(MGI:3580934|PMID:15626733)
(MGI:6201960|PMID:21873635)
(MGI:1306978|PMID:9806545)
MGI
GO_Central
PMID:9806545 PMID:15626733 PMID:21873635 GO_REF:0000096 MGI:1306978 MGI:3580934 MGI:4834177 MGI:6201960 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Pnp purine-nucleoside phosphorylase acts_upstream_of_or_within IMP (MGI:1859999|PMID:10859343) MGI PMID:10859343 MGI:1859999 NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,202,694
JBrowse link
G Polb polymerase (DNA directed), beta acts_upstream_of_or_within IMP (MGI:1334987|PMID:10197627) MGI PMID:10197627 MGI:1334987 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:2450507|PMID:12604618)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:12604618 PMID:21873635 MGI:2450507 MGI:6201960 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of IMP
IGI
(MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:3584078 NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661
JBrowse link
G Sfn stratifin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:133,327,867...133,329,479
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Sirt1 sirtuin 1 involved_in IDA (MGI:5297787|PMID:16269335) UniProt PMID:16269335 MGI:5297787 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Skil SKI-like acts_upstream_of IMP (MGI:1858539|PMID:10811619) MGI PMID:10811619 MGI:1858539 NCBI chr 3:31,149,122...31,177,072
Ensembl chr 3:31,149,207...31,176,726
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial acts_upstream_of_or_within IMP (MGI:3691744|PMID:15642323) MGI PMID:15642323 MGI:3691744 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within IDA (MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a acts_upstream_of_or_within IMP (MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:3709926|PMID:17242187)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:17242187 PMID:21873635 MGI:3709926 MGI:6201960 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Topors topoisomerase I binding, arginine/serine-rich involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:40,259,601...40,269,868
Ensembl chr 4:40,259,601...40,269,850
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within IMP (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 9:60,700,488...60,787,713
Ensembl chr 9:60,701,824...60,787,652
JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of IMP (MGI:4839431|PMID:19966869) MGI PMID:19966869 MGI:4839431 NCBI chr 7:111,621,846...111,710,593
Ensembl chr 7:111,622,711...111,710,868
JBrowse link
G Xpa xeroderma pigmentosum, complementation group A acts_upstream_of_or_within IMP (MGI:1913261|PMID:11005836) MGI PMID:11005836 MGI:1913261 NCBI chr 4:46,175,222...46,196,345
Ensembl chr 4:46,155,347...46,196,311
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IGI (MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:3584078 NCBI chr11:79,980,205...80,026,623
Ensembl chr11:79,980,226...80,026,620
JBrowse link
G Bag6 BCL2-associated athanogene 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,354,132...35,366,297
Ensembl chr17:35,354,154...35,366,298
JBrowse link
G Bbc3 BCL2 binding component 3 acts_upstream_of_or_within IMP (MGI:3603103|PMID:16151013) MGI PMID:16151013 MGI:3603103 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Brca2 breast cancer 2, early onset acts_upstream_of_or_within IMP
IGI
(MGI:3579926|PMID:15735671)
(MGI:3714678|PMID:17476307)
MGI PMID:15735671 PMID:17476307 MGI:3579926 MGI:3714678 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
JBrowse link
G Cdip1 cell death inducing Trp53 target 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000008 MGI:2154458 MGI:6201960 NCBI chr16:4,583,325...4,608,156
Ensembl chr16:4,568,212...4,608,156
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) acts_upstream_of_or_within IMP (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within IMP (MGI:1354114|PMID:10710310) MGI PMID:10710310 MGI:1354114 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in IMP (MGI:5298149|PMID:21896779) UniProt PMID:21896779 MGI:5298149 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Dyrk2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,691,507...118,725,144
Ensembl chr10:118,691,508...118,706,114
JBrowse link
G Ell3 elongation factor RNA polymerase II-like 3 acts_upstream_of IMP (MGI:5438719|PMID:22768269) MGI PMID:22768269 MGI:5438719 NCBI chr 2:121,269,508...121,273,082
Ensembl chr 2:121,269,491...121,274,759
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:81,470,329...81,536,278
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 acts_upstream_of_or_within
involved_in
IGI
IBA
(MGI:3619785|PMID:16537918)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:16537918 PMID:21873635 MGI:3619785 MGI:6201960 NCBI chr 3:103,647,131...103,699,210
Ensembl chr 3:103,647,131...103,698,879
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in
acts_upstream_of_or_within
IBA
IGI
(MGI:6201960|PMID:21873635)
(MGI:3619785|PMID:16537918)
GO_Central
MGI
PMID:16537918 PMID:21873635 MGI:3619785 MGI:6201960 NCBI chr 6:38,664,447...38,853,236
Ensembl chr 6:38,671,325...38,853,099
JBrowse link
G Ifi204 interferon activated gene 204 acts_upstream_of_or_within ISO (MGI:2682549|PMID:14654789) MGI PMID:14654789 MGI:2682549 NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509
JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within IGI (MGI:1334080|PMID:10097137) MGI PMID:10097137 MGI:1334080 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 acts_upstream_of_or_within IMP (MGI:3784021|PMID:11896600) MGI PMID:11896600 MGI:3784021 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Phlda3 pleckstrin homology like domain, family A, member 3 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within IDA (MGI:1858284|PMID:10807576) MGI PMID:10807576 MGI:1858284 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pml promyelocytic leukemia involved_in IMP (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798
JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within IDA (MGI:2183272|PMID:12135983) MGI PMID:12135983 MGI:2183272 NCBI chr 9:108,867,635...108,886,860
Ensembl chr 9:108,867,633...108,886,845
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:87,496,680...87,519,069
Ensembl chr12:87,495,845...87,519,044
JBrowse link
G Tmem109 transmembrane protein 109 involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:4437179|PMID:20060811)
GO_Central
MGI
PMID:20060811 PMID:21873635 MGI:4437179 MGI:6201960 NCBI chr19:10,848,021...10,859,107
Ensembl chr19:10,848,024...10,859,365
JBrowse link
G Topors topoisomerase I binding, arginine/serine-rich acts_upstream_of_or_within IDA (MGI:3578084|PMID:15735665) MGI PMID:15735665 MGI:3578084 NCBI chr 4:40,259,601...40,269,868
Ensembl chr 4:40,259,601...40,269,850
JBrowse link
G Trp53 transformation related protein 53 involved_in
acts_upstream_of_or_within
IMP
IGI
IDA
ISO
(MGI:4944151|PMID:20818388)
(MGI:3584078|PMID:15983387)
(MGI:2183272|PMID:12135983)
(MGI:5882892|PMID:16213212)
(MGI:3652689|PMID:16777961)
(MGI:3690827|PMID:16286009)
(MGI:2682549|PMID:14654789)
(MGI:2675761|PMID:12952892)
(MGI:3714678|PMID:17476307)
BHF-UCL
MGI
CAFA
PMID:12135983 PMID:12952892 PMID:14654789 PMID:15983387 PMID:16213212 More... GO_REF:0000008 MGI:2154458 MGI:2183272 MGI:2675761 MGI:2682549 MGI:3584078 MGI:3652689 MGI:3690827 MGI:3714678 MGI:4944151 MGI:5882892 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp63 transformation related protein 63 acts_upstream_of_or_within IMP (MGI:3693137|PMID:17122775) MGI PMID:17122775 MGI:3693137 NCBI chr16:25,502,513...25,710,838
Ensembl chr16:25,502,513...25,710,852
JBrowse link
G Trp73 transformation related protein 73 involved_in
acts_upstream_of
ISO
IGI
(MGI:3584078|PMID:15983387) MGI PMID:15983387 GO_REF:0000096 MGI:3584078 MGI:4834177 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817
JBrowse link
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 involved_in IMP (MGI:3774040|PMID:18056262) UniProt PMID:18056262 MGI:3774040 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IMP (MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:5621265 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Atf4 activating transcription factor 4 involved_in IDA
IMP
(MGI:5496937|PMID:23624402)
(MGI:4879048|PMID:21159964)
UniProt PMID:21159964 PMID:23624402 MGI:4879048 MGI:5496937 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Bag6 BCL2-associated athanogene 6 involved_in IMP (MGI:3774040|PMID:18056262) UniProt PMID:18056262 MGI:3774040 NCBI chr17:35,354,132...35,366,297
Ensembl chr17:35,354,154...35,366,298
JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within IGI (MGI:2667259|PMID:12847083)
(MGI:3575207|PMID:15776018)
MGI PMID:12847083 PMID:15776018 MGI:2667259 MGI:3575207 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein involved_in
acts_upstream_of_or_within
ISO
IGI
(MGI:2667259|PMID:12847083)
(MGI:3575207|PMID:15776018)
MGI PMID:12847083 PMID:15776018 GO_REF:0000096 MGI:2667259 MGI:3575207 MGI:4834177 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 involved_in IBA
IMP
ISO
(MGI:6201960|PMID:21873635)
(MGI:4879048|PMID:21159964), (MGI:5448480|PMID:22761832), (MGI:5621265|PMID:16407291)
GO_Central
UniProt
MGI
PMID:16407291 PMID:21159964 PMID:21873635 PMID:22761832 GO_REF:0000096 MGI:4834177 MGI:4879048 MGI:5448480 MGI:5621265 MGI:6201960 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within ISS (MGI:3575207|PMID:15776018) MGI PMID:15776018 MGI:3575207 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:141,503,488...141,557,981
Ensembl chr 7:141,503,488...141,557,984
JBrowse link
G Casp12 caspase 12 involved_in
acts_upstream_of_or_within
IMP
IGI
IDA
TAS
(MGI:1351404|PMID:10638761)
(MGI:2667259|PMID:12847083)
(MGI:5634893|PMID:12097332)
(MGI:5306292|PMID:18309324)
ParkinsonsUK-UCL
MGI
UniProt
PMID:10638761 PMID:12097332 PMID:12847083 PMID:18309324 MGI:1351404 MGI:2667259 MGI:5306292 MGI:5634893 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 involved_in NAS (MGI:5634893|PMID:12097332) ParkinsonsUK-UCL PMID:12097332 MGI:5634893 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase involved_in ISO (PMID:15123740) ParkinsonsUK-UCL PMID:15123740 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp9 caspase 9 involved_in NAS (MGI:5634893|PMID:12097332) ParkinsonsUK-UCL PMID:12097332 MGI:5634893 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta involved_in IMP (MGI:1335331|PMID:9531536) ParkinsonsUK-UCL PMID:9531536 MGI:1335331 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Chac1 ChaC, cation transport regulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
JBrowse link
G Dab2ip disabled 2 interacting protein involved_in IMP (MGI:3796479|PMID:18281285) BHF-UCL PMID:18281285 MGI:3796479 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
IDA
(MGI:1335331|PMID:9531536), (MGI:4879048|PMID:21159964)
(MGI:2158984|PMID:11854325)
(MGI:6201960|PMID:21873635)
(MGI:5496937|PMID:23624402)
ParkinsonsUK-UCL
MGI
GO_Central
UniProt
PMID:9531536 PMID:11854325 PMID:21159964 PMID:21873635 PMID:23624402 GO_REF:0000096 MGI:1335331 MGI:2158984 MGI:4834177 MGI:4879048 MGI:5496937 MGI:6201960 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:80,145,790...80,184,399
Ensembl chr 2:80,145,810...80,184,387
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within IMP (MGI:2136067|PMID:11430819) MGI PMID:11430819 MGI:2136067 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 involved_in
acts_upstream_of_or_within
IBA
IMP
IDA
(MGI:6201960|PMID:21873635)
(MGI:3840374|PMID:19328063)
(MGI:1929557|PMID:11146108)
GO_Central
ParkinsonsUK-UCL
MGI
PMID:11146108 PMID:19328063 PMID:21873635 MGI:1929557 MGI:3840374 MGI:6201960 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1346198|PMID:9755171)
GO_Central
MGI
PMID:9755171 PMID:21873635 MGI:1346198 MGI:6201960 NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in IMP (MGI:4366390|PMID:19752026) UniProt PMID:19752026 MGI:4366390 NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IDA (MGI:5619738|PMID:23028846) CACAO PMID:23028846 MGI:5619738 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Ins2 insulin II acts_upstream_of_or_within IMP (MGI:2158984|PMID:11854325) MGI PMID:11854325 MGI:2158984 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 involved_in IMP (MGI:4366390|PMID:19752026) UniProt PMID:19752026 MGI:4366390 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in IMP (MGI:5616327|PMID:12050113) ParkinsonsUK-UCL PMID:12050113 MGI:5616327 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of IMP (MGI:4836774|PMID:20811152) MGI PMID:20811152 MGI:4836774 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in IMP (MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:5621265 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pml promyelocytic leukemia acts_upstream_of_or_within IMP (MGI:4849347|PMID:21030605) MGI PMID:21030605 MGI:4849347 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Qrich1 glutamine-rich 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:108,394,010...108,437,366
Ensembl chr 9:108,394,005...108,437,362
JBrowse link
G Rnf186 ring finger protein 186 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:138,694,430...138,695,676
Ensembl chr 4:138,694,423...138,695,676
JBrowse link
G Selenok selenoprotein K involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:29,690,337...29,697,031
Ensembl chr14:29,690,265...29,697,619
JBrowse link
G Spop speckle-type BTB/POZ protein acts_upstream_of IGI (MGI:4836774|PMID:20811152) MGI PMID:20811152 MGI:4836774 NCBI chr11:95,304,909...95,384,236
Ensembl chr11:95,304,906...95,384,232
JBrowse link
G Syvn1 synovial apoptosis inhibitor 1, synoviolin acts_upstream_of IMP (MGI:3575050|PMID:15611074) MGI PMID:15611074 MGI:3575050 NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within IDA
IMP
(MGI:3050914|PMID:15304216) MGI PMID:15304216 MGI:3050914 NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930
JBrowse link
G Tmem117 transmembrane protein 117 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:94,527,066...94,993,978
Ensembl chr15:94,527,113...94,993,979
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trp53 transformation related protein 53 involved_in IMP (MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:5621265 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 5:65,694,588...65,756,332
Ensembl chr 5:65,694,576...65,756,331
JBrowse link
G Xbp1 X-box binding protein 1 involved_in IMP (MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:3840374 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd10 programmed cell death 10 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:75,423,797...75,464,159
Ensembl chr 3:75,423,797...75,464,163
JBrowse link
G Stk25 serine/threonine kinase 25 (yeast) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:93,548,473...93,581,937
Ensembl chr 1:93,547,473...93,586,381
JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in IMP (MGI:3700897|PMID:17189429) MGI PMID:17189429 MGI:3700897 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within IMP (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 involved_in IDA (MGI:5784990|PMID:14752510) ParkinsonsUK-UCL PMID:14752510 MGI:5784990 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 involved_in IDA (MGI:5474549|PMID:21716255) CAFA PMID:21716255 MGI:5474549 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Scn2a sodium channel, voltage-gated, type II, alpha acts_upstream_of_or_within IMP (MGI:2179539|PMID:10827969) MGI PMID:10827969 MGI:2179539 NCBI chr 2:65,451,108...65,597,791
Ensembl chr 2:65,451,115...65,597,791
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor, beta 2 acts_upstream_of IGI (MGI:3654719|PMID:16571598) MGI PMID:16571598 MGI:3654719 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2, mitochondrial involved_in ISO protein:altered expression:liver (rat) RGD
MGI
PMID:29589772 GO_REF:0000096 MGI:4417868 RGD:14975297 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:97,187,753...97,210,276
Ensembl chr 6:97,187,650...97,210,276
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within IMP (MGI:2679141|PMID:12855558) MGI PMID:12855558 MGI:2679141 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IMP (MGI:5492227|PMID:23568032), (MGI:5544856|PMID:23979599) UniProt PMID:23568032 PMID:23979599 MGI:5492227 MGI:5544856 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:3587135|PMID:16085184)
GO_Central
MGI
PMID:16085184 PMID:21873635 MGI:3587135 MGI:6201960 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within IMP (MGI:2153292|PMID:11562367), (MGI:3613414|PMID:15663476)
(MGI:3698597|PMID:16373599)
MGI PMID:11562367 PMID:15663476 PMID:16373599 MGI:2153292 MGI:3613414 MGI:3698597 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gskip GSK3B interacting protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:105,651,611...105,669,317
Ensembl chr12:105,651,088...105,669,282
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO RGD
MGI
PMID:15659221 GO_REF:0000096 MGI:4417868 RGD:1641883 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(MGI:3829088|PMID:18948261)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:18948261 PMID:21873635 GO_REF:0000096 MGI:3829088 MGI:4834177 MGI:6201960 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
JBrowse link
G Mapt microtubule-associated protein tau involved_in ISO RGD
MGI
PMID:12420308 GO_REF:0000096 MGI:4417868 RGD:8158111 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Melk maternal embryonic leucine zipper kinase acts_upstream_of_or_within IDA (MGI:3829088|PMID:18948261) MGI PMID:18948261 MGI:3829088 NCBI chr 4:44,300,876...44,364,675
Ensembl chr 4:44,300,876...44,364,675
JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of IMP (MGI:4881403|PMID:19661248) MGI PMID:19661248 MGI:4881403 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
JBrowse link
G Pml promyelocytic leukemia acts_upstream_of_or_within IMP (MGI:4849347|PMID:21030605) MGI PMID:21030605 MGI:4849347 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within IDA (MGI:1333612|PMID:10082581) MGI PMID:10082581 MGI:1333612 NCBI chr 9:96,352,990...96,360,728
Ensembl chr 9:96,352,990...96,360,728
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial acts_upstream_of_or_within IMP (MGI:3691744|PMID:15642323) MGI PMID:15642323 MGI:3691744 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:121,521,599...121,618,269
Ensembl chr14:121,523,755...121,617,423
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within IMP (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 9:60,700,488...60,787,713
Ensembl chr 9:60,701,824...60,787,652
JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:25,984,452...25,998,568
Ensembl chr15:25,984,452...25,998,567
JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within IGI (MGI:5566519|PMID:20436477) MGI PMID:20436477 MGI:5566519 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
ISS
(MGI:5514134|PMID:18188704) MGI
UniProt
PMID:18188704 GO_REF:0000096 MGI:4834177 MGI:5514134 NCBI chr19:44,127,685...44,134,909
Ensembl chr19:44,127,685...44,134,885
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within IDA (MGI:2158099|PMID:11700312) MGI PMID:11700312 MGI:2158099 NCBI chr 2:165,436,892...165,613,647
Ensembl chr 2:165,436,952...165,613,647
JBrowse link
G Rhot1 ras homolog family member T1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:80,099,844...80,158,733
Ensembl chr11:80,099,845...80,158,733
JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:26,057,431...26,063,499
Ensembl chr17:26,057,431...26,063,825
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within IGI (MGI:4359364|PMID:17488777) MGI PMID:17488777 MGI:4359364 NCBI chr11:84,313,682...84,404,433
Ensembl chr11:84,313,681...84,404,348
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:15946935) UniProt PMID:15946935 NCBI chr19:31,962,046...32,080,540
Ensembl chr19:31,959,997...32,085,611
JBrowse link
G Bax BCL2-associated X protein acts_upstream_of_or_within IGI (MGI:3796786|PMID:18436203) MGI PMID:18436203 MGI:3796786 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 involved_in
acts_upstream_of_or_within
ISO
IDA
(MGI:2158578|PMID:11546872) MGI PMID:11546872 GO_REF:0000096 MGI:2158578 MGI:4834177 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdnf brain derived neurotrophic factor involved_in IGI (MGI:6295053|PMID:26708520) ARUK-UCL PMID:26708520 MGI:6295053 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bmf BCL2 modifying factor acts_upstream_of_or_within IMP (MGI:2158578|PMID:11546872) MGI PMID:11546872 MGI:2158578 NCBI chr 2:118,359,238...118,385,280
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene acts_upstream_of_or_within IGI (MGI:1932296|PMID:11290297) MGI PMID:11290297 MGI:1932296 NCBI chr 2:18,681,829...18,691,440
Ensembl chr 2:18,681,829...18,691,440
JBrowse link
G Cdk11b cyclin-dependent kinase 11B acts_upstream_of_or_within IMP (MGI:3041915|PMID:15060143) MGI PMID:15060143 MGI:3041915 NCBI chr 4:155,709,293...155,734,392
Ensembl chr 4:155,709,311...155,734,395
JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) acts_upstream_of_or_within IMP (MGI:5304595|PMID:22244329) MGI PMID:22244329 MGI:5304595 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 acts_upstream_of_or_within IMP
IGI
(MGI:3051737|PMID:15131783)
(MGI:4454604|PMID:20454446)
MGI PMID:15131783 PMID:20454446 MGI:3051737 MGI:4454604 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:4880811|PMID:21209208)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21209208 PMID:21873635 MGI:4880811 MGI:6201960 NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046
JBrowse link
G Gata4 GATA binding protein 4 involved_in IDA (MGI:5780531|PMID:25590961) BHF-UCL PMID:25590961 MGI:5780531 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 involved_in ISO RGD
MGI
PMID:25633408 GO_REF:0000096 MGI:4417868 RGD:13507311 NCBI chr 9:107,491,324...107,512,617
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 involved_in ISO RGD
MGI
PMID:25633408 GO_REF:0000096 MGI:4417868 RGD:13507311 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
JBrowse link
G Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
JBrowse link
G Hspb1 heat shock protein 1 acts_upstream_of_or_within IDA (MGI:3581090|PMID:15731106) MGI PMID:15731106 MGI:3581090 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 acts_upstream_of_or_within IMP (MGI:3688933|PMID:16857185) MGI PMID:16857185 MGI:3688933 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
JBrowse link
G Igbp1 immunoglobulin (CD79A) binding protein 1 acts_upstream_of_or_within IMP (MGI:3056248|PMID:15499020) MGI PMID:15499020 MGI:3056248 NCBI chr  X:99,537,897...99,559,731
Ensembl chr  X:99,537,897...99,559,731
JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within IMP (MGI:4867787|PMID:21124965) MGI PMID:21124965 MGI:4867787 NCBI chr 8:48,120,213...48,128,627
Ensembl chr 8:48,120,213...48,128,591
JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within IMP (MGI:3700423|PMID:14735464) MGI PMID:14735464 MGI:3700423 NCBI chr 2:90,967,705...91,013,404
Ensembl chr 2:90,967,705...91,014,182
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within IMP
IGI
(MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:89,338,114...89,346,650
Ensembl chr15:89,338,116...89,348,671
JBrowse link
G Maz MYC-associated zinc finger protein (purine-binding transcription factor) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:126,621,302...126,626,654
Ensembl chr 7:126,621,302...126,626,209
JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within IMP (MGI:4848231|PMID:21059917) MGI PMID:21059917 MGI:4848231 NCBI chr 7:15,908,684...15,920,435
Ensembl chr 7:15,909,015...15,920,429
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) ARUK-UCL PMID:26780211 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406
JBrowse link
G Mnt max binding protein acts_upstream_of_or_within IMP (MGI:2675510|PMID:12970171) MGI PMID:12970171 MGI:2675510 NCBI chr11:74,721,651...74,736,551
Ensembl chr11:74,721,746...74,736,551
JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within IDA (MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:2183867 NCBI chr15:80,896,482...81,074,937
Ensembl chr15:80,896,482...81,074,958
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within IGI
IMP
(MGI:3796786|PMID:18436203) MGI PMID:18436203 MGI:3796786 NCBI chr 8:84,900,359...84,911,396
Ensembl chr 8:84,900,360...84,911,846
JBrowse link
G Nog noggin acts_upstream_of_or_within IMP (MGI:3640733|PMID:16712836) MGI PMID:16712836 MGI:3640733 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:56,996,845...57,014,018
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Pam16 presequence translocase-asssociated motor 16 acts_upstream_of_or_within IMP (MGI:4837988|PMID:20719856) MGI PMID:20719856 MGI:4837988 NCBI chr16:4,434,330...4,442,810
Ensembl chr16:4,434,328...4,442,852
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within IGI (MGI:1932296|PMID:11290297) MGI PMID:11290297 MGI:1932296 NCBI chr11:97,579,647...97,593,260
Ensembl chr11:97,579,649...97,591,323
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within IGI (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within IGI (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003
JBrowse link
G Qars glutaminyl-tRNA synthetase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:108,385,204...108,393,140
Ensembl chr 9:108,384,905...108,393,140
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:74,327,406...74,343,495
Ensembl chr 1:74,327,406...74,344,781
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 acts_upstream_of_or_within IGI (MGI:4454604|PMID:20454446) MGI PMID:20454446 MGI:4454604 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:94,388,315...94,445,712
Ensembl chr 4:94,388,318...94,445,033
JBrowse link
G Il9 interleukin 9 acts_upstream_of_or_within IDA
IGI
(MGI:4367548|PMID:18551134) MGI PMID:18551134 MGI:4367548 NCBI chr13:56,627,090...56,630,070
Ensembl chr13:56,627,090...56,630,059
JBrowse link
G Il9r interleukin 9 receptor acts_upstream_of_or_within IMP
IGI
(MGI:4367548|PMID:18551134) MGI PMID:18551134 MGI:4367548 NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nle1 notchless homolog 1 acts_upstream_of_or_within IMP (MGI:5468737|PMID:23231322) MGI PMID:23231322 MGI:5468737 NCBI chr11:82,791,594...82,799,272
Ensembl chr11:82,791,594...82,799,237
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:44,800,036...44,809,489
Ensembl chr 7:44,803,727...44,809,489
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 BCL2-like 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:43,562,658...43,567,061
Ensembl chr 4:43,562,332...43,567,060
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IDA
ISO
(MGI:5616321|PMID:15665855) ParkinsonsUK-UCL
MGI
PMID:15665855 GO_REF:0000096 MGI:4417868 MGI:5616321 NCBI chr 2:91,812,673...91,854,515
Ensembl chr 2:91,812,673...91,854,847
JBrowse link
G Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) acts_upstream_of_or_within IDA
IGI
(MGI:5525071|PMID:22240901) MGI PMID:22240901 MGI:5525071 NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hspa1a heat shock protein 1A involved_in ISO (PMID:12150907), (PMID:20625543) ParkinsonsUK-UCL PMID:12150907 PMID:20625543 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B involved_in ISO (PMID:12150907), (PMID:20625543) ParkinsonsUK-UCL PMID:12150907 PMID:20625543 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma involved_in IMP (MGI:5495588|PMID:23453807) ParkinsonsUK-UCL PMID:23453807 MGI:5495588 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
JBrowse link
G Magea3 MAGE family member A3 involved_in ISO (PMID:12097332) ParkinsonsUK-UCL PMID:12097332 NCBI chr  X:153,731,176...153,742,027
Ensembl chr  X:153,731,539...153,732,501
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO
IMP
(MGI:5495588|PMID:23453807) MGI
ParkinsonsUK-UCL
PMID:23453807 GO_REF:0000096 MGI:4834177 MGI:5495588 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 involved_in IMP
ISO
(MGI:5613479|PMID:14652021) ParkinsonsUK-UCL
MGI
PMID:14652021 GO_REF:0000096 MGI:4834177 MGI:5613479 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within IMP (MGI:4836774|PMID:20811152) MGI PMID:20811152 MGI:4836774 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IMP
(MGI:5433837|PMID:21113145) MGI
ParkinsonsUK-UCL
PMID:21113145 GO_REF:0000096 MGI:4834177 MGI:5433837 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in IMP (MGI:5619464|PMID:21216966) ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
JBrowse link
G Selenos selenoprotein S involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:65,729,397...65,739,153
Ensembl chr 7:65,729,397...65,739,153
JBrowse link
G Syvn1 synovial apoptosis inhibitor 1, synoviolin acts_upstream_of_or_within
involved_in
IMP
ISO
(MGI:3575050|PMID:15611074) MGI PMID:15611074 GO_REF:0000096 MGI:3575050 MGI:4834177 NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within
involved_in
IGI
ISO
(MGI:5525071|PMID:22240901) MGI PMID:22240901 GO_REF:0000096 MGI:4834177 MGI:5525071 NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930
JBrowse link
G Txndc12 thioredoxin domain containing 12 (endoplasmic reticulum) acts_upstream_of_or_within ISO (MGI:3819890|PMID:18628206) MGI PMID:18628206 MGI:3819890 NCBI chr 4:108,691,875...108,719,317
Ensembl chr 4:108,691,798...108,719,324
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IMP (MGI:3629256|PMID:16571599) BHF-UCL PMID:16571599 MGI:3629256 NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IMP (MGI:3697528|PMID:17116640) ParkinsonsUK-UCL PMID:17116640 MGI:3697528 NCBI chr 9:44,290,787...44,303,666
Ensembl chr 9:44,290,787...44,303,666
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
IGI
(MGI:5495588|PMID:23453807)
(MGI:3697528|PMID:17116640)
ParkinsonsUK-UCL PMID:17116640 PMID:23453807 MGI:3697528 MGI:5495588 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169
JBrowse link
G Ar androgen receptor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:74,835,247...75,010,351
Ensembl chr17:74,835,290...75,010,351
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IMP (MGI:3039210|PMID:15070745) BHF-UCL PMID:15070745 MGI:3039210 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO
IGI
(MGI:5486419|PMID:22675671) MGI PMID:22675671 GO_REF:0000096 MGI:4834177 MGI:5486419 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cttn cortactin acts_upstream_of_or_within IGI (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr 7:143,989,461...144,024,743
Ensembl chr 7:143,989,470...144,024,746
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein acts_upstream_of_or_within IMP (MGI:5442513|PMID:15734730) MGI PMID:15734730 MGI:5442513 NCBI chr15:6,329,269...6,470,196
Ensembl chr15:6,329,269...6,470,193
JBrowse link
G Fcmr Fc fragment of IgM receptor acts_upstream_of_or_within IDA (MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:3576402 NCBI chr 1:130,793,514...130,808,527
Ensembl chr 1:130,793,406...130,808,528
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within IGI (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit acts_upstream_of_or_within IGI (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstp2 glutathione S-transferase, pi 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023
JBrowse link
G Gstp3 glutathione S-transferase pi 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:4,107,470...4,109,587
Ensembl chr19:4,107,477...4,109,569
JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within IDA (MGI:5491082|PMID:23468852) MGI PMID:23468852 MGI:5491082 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:1340173|PMID:10429671)
GO_Central
MGI
PMID:10429671 PMID:21873635 MGI:1340173 MGI:6201960 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within IDA (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
JBrowse link
G Itga6 integrin alpha 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:71,617,236...71,688,771
Ensembl chr 2:71,575,960...71,688,760
JBrowse link
G Itgav integrin alpha V involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:83,551,625...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lmna lamin A acts_upstream_of_or_within IMP (MGI:4879057|PMID:21151901) MGI PMID:21151901 MGI:4879057 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263
JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571
JBrowse link
G Nrp1 neuropilin 1 involved_in IMP (MGI:5287519|PMID:21828096) BHF-UCL PMID:21828096 MGI:5287519 NCBI chr 8:129,085,072...129,231,957
Ensembl chr 8:129,085,085...129,229,844
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within IDA (MGI:2673247|PMID:12897128) MGI PMID:12897128 MGI:2673247 NCBI chr 2:135,923,008...136,229,899
Ensembl chr 2:135,923,024...136,229,887
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Peli3 pellino 3 acts_upstream_of_or_within IMP
ISO
(MGI:5546581|PMID:23950925) MGI PMID:23950925 MGI:5546581 NCBI chr19:4,979,745...4,993,155
Ensembl chr19:4,979,745...4,993,155
JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (MGI:3723572|PMID:17636024) MGI PMID:17636024 MGI:3723572 NCBI chr 9:82,748,212...82,857,776
Ensembl chr 9:82,748,212...82,857,569
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within IMP (MGI:3050700|PMID:15259009) MGI PMID:15259009 MGI:3050700 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:101,206,090...101,214,363
Ensembl chr11:101,207,039...101,214,363
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within IMP (MGI:3689241|PMID:17015619) MGI PMID:17015619 MGI:3689241 NCBI chr 1:6,284,858...6,346,599
Ensembl chr 1:6,276,421...6,346,872
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:5304595|PMID:22244329) MGI PMID:22244329 GO_REF:0000096 MGI:4834177 MGI:5304595 NCBI chr19:5,687,569...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO
IGI
(MGI:5521568|PMID:22089168) MGI PMID:22089168 GO_REF:0000096 MGI:4834177 MGI:5521568 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 acts_upstream_of_or_within IMP (MGI:4456959|PMID:11493700) MGI PMID:11493700 MGI:4456959 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Scg2 secretogranin II involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:79,412,083...79,417,743
Ensembl chr 1:79,412,386...79,417,837
JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within IDA (MGI:3609513|PMID:16226406) MGI PMID:16226406 MGI:3609513 NCBI chr19:32,100,127...32,367,285
Ensembl chr19:32,100,127...32,367,114
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:61,677,117...61,918,327
Ensembl chr 8:61,676,906...61,849,105
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:58,582,370...58,599,857
Ensembl chr 3:58,582,359...58,599,821
JBrowse link
G Src Rous sarcoma oncogene involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:157,265,790...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:55,730,226...55,922,091
Ensembl chr19:55,730,252...55,922,086
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:47,353,222...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 involved_in IMP (MGI:2150820|PMID:11567634) BHF-UCL PMID:11567634 MGI:2150820 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069
JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IC (MGI:2150820|PMID:11567634) BHF-UCL PMID:11567634 MGI:2150820 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IDA (MGI:5287519|PMID:21828096) BHF-UCL PMID:21828096 MGI:5287519 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Yap1 yes-associated protein 1 acts_upstream_of_or_within IGI (MGI:3818355|PMID:17980593) MGI PMID:17980593 MGI:3818355 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
G Zmynd11 zinc finger, MYND domain containing 11 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:9,734,872...9,816,050
Ensembl chr13:9,734,869...9,815,366
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:126,911,154...126,929,039
Ensembl chr10:126,911,153...126,929,038
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within IDA (MGI:1326939|PMID:9878060) MGI PMID:9878060 MGI:1326939 NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
JBrowse link
G Col2a1 collagen, type II, alpha 1 acts_upstream_of_or_within IMP (MGI:1097047|PMID:9299161) MGI PMID:9299161 MGI:1097047 NCBI chr15:97,873,483...97,902,722
Ensembl chr15:97,873,483...97,902,576
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Ctnna1 catenin (cadherin associated protein), alpha 1 acts_upstream_of_or_within IMP (MGI:5315030|PMID:22411810) MGI PMID:22411810 MGI:5315030 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 acts_upstream_of_or_within IDA (MGI:3777228|PMID:18322241), (MGI:3833195|PMID:18971423) MGI PMID:18322241 PMID:18971423 MGI:3777228 MGI:3833195 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 acts_upstream_of_or_within IMP (MGI:3833195|PMID:18971423) MGI PMID:18971423 MGI:3833195 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3577160|PMID:15817220)
GO_Central
MGI
PMID:15817220 PMID:21873635 MGI:3577160 MGI:6201960 NCBI chr 1:14,239,177...14,381,259
Ensembl chr 1:14,239,178...14,380,459
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:165,436,892...165,613,647
Ensembl chr 2:165,436,952...165,613,647
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:132,366,303...132,452,076
Ensembl chr 4:132,366,298...132,452,076
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:22,978,861...23,226,785
Ensembl chr10:22,978,862...23,226,684
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within IMP (MGI:3690587|PMID:16956603) MGI PMID:16956603 MGI:3690587 NCBI chr13:118,851,235...118,929,109
Ensembl chr13:118,806,327...118,928,651
JBrowse link
G Fyn Fyn proto-oncogene involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
JBrowse link
G Gas1 growth arrest specific 1 acts_upstream_of_or_within IDA (MGI:5306314|PMID:15070677) MGI PMID:15070677 MGI:5306314 NCBI chr13:60,322,219...60,325,349
Ensembl chr13:60,322,219...60,325,179
JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:7,825,499...7,842,902
Ensembl chr  X:7,825,499...7,844,310
JBrowse link
G Gdnf glial cell line derived neurotrophic factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within IDA (MGI:3610244|PMID:16086688) MGI PMID:16086688 MGI:3610244 NCBI chr 9:76,071,384...76,120,939
Ensembl chr 9:76,071,384...76,120,939
JBrowse link
G Hspa1a heat shock protein 1A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Il1b interleukin 1 beta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within IDA (MGI:84869|PMID:8950980) MGI PMID:8950980 MGI:84869 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) BHF-UCL PMID:10666185 NCBI chr 5:90,920,294...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within IDA (MGI:86755|PMID:9115640) MGI PMID:9115640 MGI:86755 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 involved_in IMP (MGI:5306563|PMID:20125124) UniProt PMID:20125124 MGI:5306563 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase 3 acts_upstream_of_or_within IDA (MGI:2178763|PMID:11050396) MGI PMID:11050396 MGI:2178763 NCBI chr 1:9,868,355...9,972,795
Ensembl chr 1:9,868,332...9,971,070
JBrowse link
G Snai2 snail family zinc finger 2 acts_upstream_of_or_within IDA (MGI:5142392|PMID:10518215) MGI PMID:10518215 MGI:5142392 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Stradb STE20-related kinase adaptor beta acts_upstream_of_or_within IDA (MGI:2656105|PMID:12574163) MGI PMID:12574163 MGI:2656105 NCBI chr 1:59,012,681...59,034,281
Ensembl chr 1:59,012,681...59,034,874
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
JBrowse link
G Tnf tumor necrosis factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:60,598,373...60,667,360
Ensembl chr10:60,598,372...60,667,360
JBrowse link
G Zc3hc1 zinc finger, C3HC type 1 acts_upstream_of_or_within IDA (MGI:2670822|PMID:12748172) MGI PMID:12748172 MGI:2670822 NCBI chr 6:30,366,383...30,391,019
Ensembl chr 6:30,366,379...30,391,027
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 involved_in ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chr 3:88,500,427...88,556,839
Ensembl chr 3:88,513,273...88,555,359
JBrowse link
G Bcl2l1 BCL2-like 1 acts_upstream_of_or_within ISO (MGI:5755333|PMID:26582200) MGI PMID:26582200 MGI:5755333 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Brca1 breast cancer 1, early onset involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO