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ONTOLOGY REPORT - ANNOTATIONS


Term:amelogenesis
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Accession:GO:0097186 term browser browse the term
Definition:The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
Synonyms:exact_synonym: enamel development



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amelogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in IDA (MGI:6716964|PMID:26403673) ARUK-UCL PMID:26403673 MGI:6716964 NCBI chr  X:167,959,110...167,970,205
Ensembl chr  X:167,959,110...167,970,196
JBrowse link
G Ascl5 achaete-scute family bHLH transcription factor 5 involved_in IMP (MGI:6305509|PMID:30504223), (MGI:7280983|PMID:34812512) UniProt PMID:30504223 PMID:34812512 MGI:6305509 MGI:7280983 NCBI chr 1:135,978,321...135,979,810
Ensembl chr 1:135,978,542...135,979,108
JBrowse link
G Atf2 activating transcription factor 2 involved_in ISO RGD
MGI
PMID:15218628 GO_REF:0000096 MGI:4417868 RGD:10053659 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator involved_in IDA (MGI:6716964|PMID:26403673) ARUK-UCL PMID:26403673 MGI:6716964 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Csf3r colony stimulating factor 3 receptor ISO RGD PMID:10206335 RGD:5134351 NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within IMP (MGI:5912858|PMID:25027178) MGI PMID:25027178 MGI:5912858 NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993
JBrowse link
G Enam enamelin acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:5634640|PMID:22813216)
(MGI:3796449|PMID:18252720), (MGI:5647983|PMID:24603688)
(MGI:3530197|PMID:15649948)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15649948 PMID:18252720 PMID:21873635 PMID:22813216 PMID:24603688 MGI:3530197 MGI:3796449 MGI:5634640 MGI:5647983 MGI:6201960 NCBI chr 5:88,635,834...88,653,908
Ensembl chr 5:88,635,834...88,653,908
JBrowse link
G Klk4 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
(MGI:4354666|PMID:19578120), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:19578120 PMID:21454549 PMID:21873635 PMID:22243248 GO_REF:0000119 MGI:4354666 MGI:4834177 MGI:5008529 MGI:5502300 MGI:6201960 NCBI chr 7:43,530,584...43,535,228
Ensembl chr 7:43,530,584...43,535,228
JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:43,483,581...43,500,605
Ensembl chr 7:43,491,395...43,500,605
JBrowse link
G Mmp20 matrix metallopeptidase 20 (enamelysin) acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:3522683|PMID:15557396), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15557396 PMID:21454549 PMID:21873635 PMID:22243248 MGI:3522683 MGI:5008529 MGI:5502300 MGI:6201960 NCBI chr 9:7,628,232...7,674,969
Ensembl chr 9:7,628,232...7,674,980
JBrowse link
G Perp PERP, TP53 apoptosis effector acts_upstream_of_or_within IMP (MGI:5317035|PMID:21285247) MGI PMID:21285247 MGI:5317035 NCBI chr10:18,720,819...18,732,821
Ensembl chr10:18,720,768...18,732,821
JBrowse link
G Relt RELT tumor necrosis factor receptor involved_in IMP
ISO
IBA
(MGI:6368096|PMID:30506946)
(MGI:6201960|PMID:21873635)
UniProt
MGI
GO_Central
PMID:21873635 PMID:30506946 GO_REF:0000119 MGI:4834177 MGI:6201960 MGI:6368096 NCBI chr 7:100,495,054...100,512,690
Ensembl chr 7:100,495,054...100,512,653
JBrowse link
G Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 involved_in IMP (MGI:5520028|PMID:23375655), (MGI:6716966|PMID:27752731) ARUK-UCL PMID:23375655 PMID:27752731 MGI:5520028 MGI:6716966 NCBI chr12:102,094,986...102,239,562
Ensembl chr12:102,094,992...102,233,350
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 involved_in IDA (MGI:6716964|PMID:26403673) ARUK-UCL PMID:26403673 MGI:6716964 NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
JBrowse link
enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in IDA
IBA
(MGI:6716964|PMID:26403673)
(MGI:6201960|PMID:21873635)
ARUK-UCL
GO_Central
PMID:21873635 PMID:26403673 MGI:6201960 MGI:6716964 NCBI chr  X:167,959,110...167,970,205
Ensembl chr  X:167,959,110...167,970,196
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator involved_in ISO RGD
MGI
PMID:31942562 GO_REF:0000096 MGI:4417868 RGD:126928119 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Cnnm4 cyclin M4 acts_upstream_of_or_within IMP (MGI:5559016|PMID:24339795) MGI PMID:24339795 MGI:5559016 NCBI chr 1:36,510,678...36,547,857
Ensembl chr 1:36,510,701...36,547,845
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
(MGI:5432245|PMID:22732358)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:22732358 GO_REF:0000119 MGI:4834177 MGI:5432245 MGI:6201960 NCBI chr11:109,563,752...109,613,989
Ensembl chr11:109,560,575...109,613,105
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:5432245|PMID:22732358)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:22732358 MGI:5432245 MGI:6201960 NCBI chr 5:138,740,836...138,795,818
Ensembl chr 5:138,740,269...138,795,832
JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:25183529 RGD:10044263 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Itgb6 integrin beta 6 acts_upstream_of_or_within IMP (MGI:5507902|PMID:23264742) MGI PMID:23264742 MGI:5507902 NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within IMP (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within IMP (MGI:3814115|PMID:18703497) MGI PMID:18703497 MGI:3814115 NCBI chr 9:43,655,251...43,718,758
Ensembl chr 9:43,655,281...43,743,955
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within IMP (MGI:3843118|PMID:19320717) MGI PMID:19320717 MGI:3843118 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526
JBrowse link
G Tbx1 T-box 1 acts_upstream_of_or_within IMP (MGI:3848106|PMID:19233155) MGI PMID:19233155 MGI:3848106 NCBI chr16:18,399,729...18,409,412
Ensembl chr16:18,399,729...18,409,421
JBrowse link
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 acts_upstream_of_or_within IMP (MGI:5469811|PMID:23174213) MGI PMID:23174213 MGI:5469811 NCBI chr19:3,946,050...3,957,717
Ensembl chr19:3,946,050...3,957,133
JBrowse link
G Wdr72 WD repeat domain 72 acts_upstream_of_or_within IMP (MGI:5906533|PMID:26247047)
(MGI:5605934|PMID:25008349)
MGI PMID:25008349 PMID:26247047 MGI:5605934 MGI:5906533 NCBI chr 9:74,017,608...74,190,485
Ensembl chr 9:74,017,638...74,190,590
JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in IMP
IBA
(MGI:5613837|PMID:25407797)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:25407797 MGI:5613837 MGI:6201960 NCBI chr 5:88,523,967...88,533,775
Ensembl chr 5:88,523,967...88,533,775
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator involved_in IDA (MGI:6716964|PMID:26403673) ARUK-UCL PMID:26403673 MGI:6716964 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within IDA (MGI:3603472|PMID:16014627) MGI PMID:16014627 MGI:3603472 NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993
JBrowse link
G Enam enamelin acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:5647983|PMID:24603688)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:24603688 MGI:5647983 MGI:6201960 NCBI chr 5:88,635,834...88,653,908
Ensembl chr 5:88,635,834...88,653,908
JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 5:92,135,332...92,143,176
Ensembl chr 5:92,135,334...92,143,179
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 involved_in IDA (MGI:6716964|PMID:26403673) ARUK-UCL PMID:26403673 MGI:6716964 NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1, ribonuclease type III acts_upstream_of_or_within IMP (MGI:4453947|PMID:20102707) MGI PMID:20102707 MGI:4453947 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Dmp1 dentin matrix protein 1 acts_upstream_of_or_within IDA (MGI:3603472|PMID:16014627) MGI PMID:16014627 MGI:3603472 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of IMP (MGI:6443509|PMID:31336344), (MGI:6690584|PMID:30243146) MGI PMID:30243146 PMID:31336344 MGI:6443509 MGI:6690584 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28558
    developmental process 7345
      anatomical structure formation involved in morphogenesis 1418
        amelogenesis 31
          enamel mineralization + 22
Path 2
Term Annotations click to browse term
  biological_process 28558
    developmental process 7345
      anatomical structure development 6817
        animal organ development 3771
          animal organ morphogenesis 1197
            odontogenesis 154
              odontogenesis of dentin-containing tooth 111
                amelogenesis 31
                  enamel mineralization + 22
paths to the root