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ONTOLOGY REPORT - ANNOTATIONS


Term:AIM2 inflammasome complex
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Accession:GO:0097169 term browser browse the term
Definition:An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.



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AIM2 inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 located_in
part_of
ISO
IBA
(PMID:24630722)
(PMID:19158676), (PMID:19158679), (PMID:26197926), (PMID:29440442), (PMID:33980849)
GO_REF:0000033
(MGI:5807418|PMID:27846608), (PMID:19158679)
RGD
GO_Central
PMID:19158676 PMID:19158679 PMID:24630722 PMID:26197926 PMID:27846608 More... GO_REF:0000033 MGI:5807418 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
JBrowse link
G Casp1 caspase 1 part_of
located_in
ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:19158676)
(PMID:24630722)
GO_REF:0000118
GO_REF:0000033
UniProt
RGD
TreeGrafter
GO_Central
PMID:19158676 PMID:24630722 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp4 caspase 4 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Pycard PYD and CARD domain containing part_of
located_in
ISO (PMID:19158676)
(PMID:24630722)
RGD PMID:19158676 PMID:24630722 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      canonical inflammasome complex 29
        AIM2 inflammasome complex 5
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      intracellular anatomical structure 15673
        cytoplasm 12359
          cytosol 4577
            canonical inflammasome complex 29
              AIM2 inflammasome complex 5
paths to the root