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ONTOLOGY REPORT - ANNOTATIONS


Term:AMPA glutamate receptor clustering
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Accession:GO:0097113 term browser browse the term
Definition:The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
Synonyms:exact_synonym: AMPA receptor clustering;   alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering



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AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within_positive_effect
involved_in
ISO
IEA
(PMID:24328732)
GO_REF:0000107
RGD
Ensembl
PMID:24328732 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Chrdl1 chordin-like 1 involved_in IEA
ISO
GO_REF:0000107
MGI:6315865 (PMID:30344043)
Ensembl
RGD
PMID:30344043 GO_REF:0000107 NCBI chr  X:111,685,864...111,789,684 JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IMP
IBA
PMID:21525273
GO_REF:0000033
GO_Central PMID:21525273 GO_REF:0000033, RGD:8554095 NCBI chr10:55,239,397...55,267,780 JBrowse link
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO MGI:5521326 (PMID:23911104) RGD PMID:23911104 NCBI chr 4:114,103,783...114,894,696 JBrowse link
G Nlgn1 neuroligin 1 involved_in ISS
ISO
IEA
IMP
GO_REF:0000024
(PMID:12796785), (PMID:21940442)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:12796785 PMID:21940442 PMID:21940442 GO_REF:0000024 GO_REF:0000107, RGD:8553843 NCBI chr 2:110,184,987...111,110,316 JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:21558424), (PMID:21795692)
GO_REF:0000024
Ensembl
RGD
BHF-UCL
PMID:21558424 PMID:21795692 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:122,448,323...122,518,623 JBrowse link
positive regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IMP PMID:19596852 UniProt PMID:19596852 RGD:21201259 NCBI chr10:55,239,397...55,267,780 JBrowse link
G Grip2 glutamate receptor interacting protein 2 involved_in IMP PMID:20083202 UniProt PMID:20083202 RGD:4107359 NCBI chr 4:125,828,609...125,913,693 JBrowse link
G Snx27 sorting nexin 27 IMP RGD PMID:25071192 RGD:13508620 NCBI chr 2:184,824,930...184,907,931 JBrowse link
G Ssh1 slingshot protein phosphatase 1 IMP RGD PMID:20442266 RGD:11535133 NCBI chr12:48,281,756...48,343,812 JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 involved_in IMP PMID:19596852 UniProt PMID:19596852 RGD:21201259 NCBI chr16:58,511,931...58,581,530 JBrowse link
regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Frrs1l ferric-chelate reductase 1-like acts_upstream_of_or_within ISO (PMID:29276473) RGD PMID:29276473 NCBI chr 5:76,451,101...76,485,319 JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5056336 (PMID:21558424)
Ensembl
RGD
PMID:21558424 GO_REF:0000107 NCBI chr 7:122,448,323...122,518,623 JBrowse link
G Shisa6 shisa family member 6 involved_in ISO (PMID:26931375) RGD PMID:26931375 NCBI chr10:51,396,806...51,691,156 JBrowse link
G Shisa7 shisa family member 7 NOT|involved_in ISO (PMID:31601770)
(PMID:29199957)
RGD PMID:29199957 PMID:31601770 NCBI chr 1:78,022,680...78,041,748 JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (PMID:25429150) RGD PMID:25429150 NCBI chr 2:136,532,912...136,668,560 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular component organization or biogenesis 7188
        cellular component organization 6904
          membrane organization 819
            postsynaptic membrane organization 55
              AMPA glutamate receptor clustering 14
                negative regulation of AMPA glutamate receptor clustering 0
                positive regulation of AMPA glutamate receptor clustering 5
                regulation of AMPA glutamate receptor clustering + 10
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular localization 3677
        cellular macromolecule localization 2715
          protein localization 2703
            protein localization to membrane 668
              receptor clustering 82
                neurotransmitter-gated ion channel clustering 22
                  glutamate receptor clustering 14
                    AMPA glutamate receptor clustering 14
                      negative regulation of AMPA glutamate receptor clustering 0
                      positive regulation of AMPA glutamate receptor clustering 5
                      regulation of AMPA glutamate receptor clustering + 10
paths to the root