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ONTOLOGY REPORT - ANNOTATIONS


Term:scaffold protein binding
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Accession:GO:0097110 term browser browse the term
Definition:Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.


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scaffold protein binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:1624291
RGD:1600115
G Adcy6 adenylate cyclase 6 JBrowse link 7 140,270,678 140,291,722 RGD:1624291
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:2313285
RGD:1624291
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:9684988
RGD:11576289
RGD:9684984
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
RGD:1600115
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:1624291
RGD:1600115
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:5491011
G Casp4 caspase 4 JBrowse link 8 2,616,391 2,651,682 RGD:5491011
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:1624291
RGD:1600115
G Cdc37 cell division cycle 37, HSP90 cochaperone JBrowse link 8 22,160,922 22,173,797 RGD:1600115
RGD:1624291
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:7205692
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
G Cit citron rho-interacting serine/threonine kinase JBrowse link 12 46,334,669 46,494,152 RGD:1624291
G Cript CXXC repeat containing interactor of PDZ3 domain JBrowse link 6 10,594,147 10,602,103 RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:11568073
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:1624291
RGD:1600115
RGD:2313285
G Dlgap3 DLG associated protein 3 JBrowse link 5 145,234,757 145,304,536 RGD:8554380
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:628355
G Dynll2 dynein light chain LC8-type 2 JBrowse link 10 75,262,536 75,281,302 RGD:628355
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:1624291
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:2313285
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1624291
RGD:1600115
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:8554370
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:13432036
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13513989
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:21201273
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:21201273
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:8554380
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:1624291
RGD:1600115
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 JBrowse link 4 180,423,452 180,800,088 RGD:1624291
G Kars lysyl-tRNA synthetase JBrowse link 19 44,212,205 44,231,209 RGD:1624291
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
RGD:1600115
RGD:10047293
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1600115
RGD:1624291
G Kif1b kinesin family member 1B JBrowse link 5 165,994,803 166,133,497 RGD:8553481
G Kif5a kinesin family member 5A JBrowse link 7 70,515,832 70,552,897 RGD:4107038
G Krt15 keratin 15 JBrowse link 10 88,046,803 88,050,622 RGD:1624291
G Krt18 keratin 18 JBrowse link 7 143,629,455 143,633,131 RGD:1624291
G Krt5 keratin 5 JBrowse link 7 143,320,142 143,324,536 RGD:1624291
RGD:1600115
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:1624291
G Lrp4 LDL receptor related protein 4 JBrowse link 3 80,362,643 80,416,684 RGD:8554698
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1600115
RGD:1624291
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:10047313
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1624291
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:12798522
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:1624291
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:5491011
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:8554165
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7794688
RGD:1600115
RGD:1624291
RGD:1599542
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:5491011
G P2ry1 purinergic receptor P2Y1 JBrowse link 2 151,314,818 151,320,312 RGD:8554370
G Panx1 Pannexin 1 JBrowse link 8 13,567,185 13,606,040 RGD:5491011
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1600115
RGD:1624291
G Phf6 PHD finger protein 6 JBrowse link X 158,698,353 158,739,855 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1599255
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:8554380
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:8554380
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Tcof1 treacle ribosome biogenesis factor 1 JBrowse link 18 56,081,863 56,115,719 RGD:1624291
RGD:13792537
G Trem1 triggering receptor expressed on myeloid cells 1 JBrowse link 9 14,727,887 14,743,371 RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Ubtf upstream binding transcription factor JBrowse link 10 90,250,275 90,265,772 RGD:1624291
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:1624291
RGD:1600115
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:5491011
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:1624291

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  molecular_function 20377
    binding 16798
      protein binding 14233
        scaffold protein binding 77
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.