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ONTOLOGY REPORT - ANNOTATIONS


Term:endothelial tip cell fate specification
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Accession:GO:0097102 term browser browse the term
Definition:The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
Synonyms:exact_synonym: angiogenic tip cell fate specification


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endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5466218|PMID:22282195) UniProt PMID:22282195 MGI:5466218 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604
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Term Annotations click to browse term
  biological_process 11981
    developmental process 5685
      anatomical structure formation involved in morphogenesis 1106
        angiogenesis 460
          sprouting angiogenesis 119
            endothelial tip cell fate specification 1
Path 2
Term Annotations click to browse term
  biological_process 11981
    developmental process 5685
      anatomical structure development 5314
        multicellular organism development 4870
          system development 4587
            circulatory system development 1105
              vasculature development 698
                blood vessel development 661
                  blood vessel endothelial cell differentiation 8
                    blood vessel endothelial cell fate commitment 2
                      blood vessel endothelial cell fate specification 2
                        endothelial tip cell fate specification 1
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