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ONTOLOGY REPORT - ANNOTATIONS


Term:endothelial tip cell fate specification
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Accession:GO:0097102 term browser browse the term
Definition:The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
Synonyms:exact_synonym: angiogenic tip cell fate specification



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endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5466218|PMID:22282195) UniProt PMID:22282195 MGI:5466218 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759
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Term Annotations click to browse term
  biological_process 12659
    developmental process 5914
      anatomical structure formation involved in morphogenesis 1149
        angiogenesis 481
          sprouting angiogenesis 124
            endothelial tip cell fate specification 1
Path 2
Term Annotations click to browse term
  biological_process 12659
    developmental process 5914
      anatomical structure development 5517
        multicellular organism development 5047
          system development 4749
            circulatory system development 1144
              vasculature development 726
                blood vessel development 688
                  blood vessel endothelial cell differentiation 8
                    blood vessel endothelial cell fate commitment 2
                      blood vessel endothelial cell fate specification 2
                        endothelial tip cell fate specification 1
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