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ONTOLOGY REPORT - ANNOTATIONS


Term:motor neuron apoptotic process
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Accession:GO:0097049 term browser browse the term
Definition:Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
Synonyms:exact_synonym: motoneuron apoptosis
 narrow_synonym: motor neuron apoptosis



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motor neuron apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase, RNA-specific, B1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4840554 (MGI:4831065|PMID:20826656)
Ensembl
RGD
PMID:20826656 GO_REF:0000107 MGI:4831065 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
JBrowse link
G Agrn agrin acts_upstream_of ISO MGI:1929777 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Atf2 activating transcription factor 2 involved_in ISO
IEA
MGI:3720850 (MGI:5007596|PMID:21533046)
GO_REF:0000107
RGD
Ensembl
PMID:21533046 GO_REF:0000107 MGI:5007596 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of
acts_upstream_of_or_within
ISO MGI:1857429 (MGI:3580738|PMID:15944391), (MGI:3695831|PMID:17192424)
MGI:1857429 (MGI:3029650|PMID:12917363)
RGD PMID:12917363 PMID:15944391 PMID:17192424 MGI:3029650 MGI:3580738 MGI:3695831 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of
involved_in
ISO
IEA
(MGI:77306|PMID:7472523)
GO_REF:0000107
RGD
Ensembl
PMID:7472523 GO_REF:0000107 MGI:77306 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cntfr ciliary neurotrophic factor receptor acts_upstream_of
involved_in
ISO
IEA
MGI:2181046|MGI:3528869 (MGI:2137500|PMID:11312299), (MGI:3798128|PMID:18588528)
GO_REF:0000107
RGD
Ensembl
PMID:11312299 PMID:18588528 GO_REF:0000107 MGI:2137500 MGI:3798128 NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 acts_upstream_of
involved_in
ISO
IEA
MGI:1929072|MGI:1929598 (MGI:1097830|PMID:9338783)
GO_REF:0000107
RGD
Ensembl
PMID:9338783 GO_REF:0000107 MGI:1097830 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within ISO (MGI:2675560|PMID:13679421) RGD PMID:13679421 MGI:2675560 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
MGI:1856334|MGI:1861923 (MGI:2675560|PMID:13679421)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:13679421 GO_REF:0000033 GO_REF:0000118 MGI:2675560 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Musk muscle associated receptor tyrosine kinase acts_upstream_of ISO MGI:1929066 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932
JBrowse link
G Nefl neurofilament light chain acts_upstream_of ISO MGI:2180095 (MGI:1096547|PMID:7946341), (MGI:1861055|PMID:10884316) RGD PMID:7946341 PMID:10884316 MGI:1096547 MGI:1861055 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Rapsn receptor-associated protein of the synapse acts_upstream_of ISO MGI:2148091 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 3:77,015,073...77,024,378
Ensembl chr 3:76,983,471...77,024,373
JBrowse link
G Rhoa ras homolog family member A acts_upstream_of ISO (MGI:3588743|PMID:15071095) RGD PMID:15071095 MGI:3588743 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3588743|PMID:15071095)
GO_REF:0000107
RGD
Ensembl
PMID:15071095 GO_REF:0000107 MGI:3588743 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Slc1a1 solute carrier family 1 member 1 acts_upstream_of_or_within ISO MGI:2655190 (MGI:5508628|PMID:16858406) RGD PMID:16858406 MGI:5508628 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO MGI:6451766 (MGI:6141536|PMID:28237315) RGD PMID:28237315 MGI:6141536 NCBI chr 3:109,007,658...109,072,904
Ensembl chr 3:109,008,135...109,072,911
JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,802,968...198,823,032
Ensembl chr 1:198,802,971...198,823,418
JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO
GO_REF:0000107
MGI:1857091 (MGI:3784333|PMID:10952021), (MGI:6196751|PMID:29890290)
Ensembl
RGD
PMID:10952021 PMID:29890290 GO_REF:0000107 MGI:3784333 MGI:6196751 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857
JBrowse link
negative regulation of motor neuron apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag1 BAG cochaperone 1 acts_upstream_of_or_within ISO MGI:3528234 (MGI:3603966|PMID:16116448) RGD PMID:16116448 MGI:3603966 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:77306|PMID:7472523)
GO_REF:0000107
RGD
Ensembl
PMID:7472523 GO_REF:0000107 MGI:77306 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cntfr ciliary neurotrophic factor receptor acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2181046|MGI:3528869 (MGI:2137500|PMID:11312299), (MGI:3798128|PMID:18588528)
GO_REF:0000107
RGD
Ensembl
PMID:11312299 PMID:18588528 GO_REF:0000107 MGI:2137500 MGI:3798128 NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392
JBrowse link
G Crlf1 cytokine receptor-like factor 1 involved_in ISO (MGI:2677656|PMID:14523086) RGD PMID:14523086 MGI:2677656 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1929072|MGI:1929598 (MGI:1097830|PMID:9338783)
GO_REF:0000107
RGD
Ensembl
PMID:9338783 GO_REF:0000107 MGI:1097830 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 acts_upstream_of_or_within ISO MGI:3769117 (MGI:5605640|PMID:25100604) RGD PMID:25100604 MGI:5605640 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3760641 (MGI:5605640|PMID:25100604)
Ensembl
RGD
PMID:25100604 GO_REF:0000107 MGI:5605640 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Nefl neurofilament light chain acts_upstream_of_or_within ISO MGI:2180095 (MGI:1096547|PMID:7946341), (MGI:1861055|PMID:10884316) RGD PMID:7946341 PMID:10884316 MGI:1096547 MGI:1861055 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (MGI:3588743|PMID:15071095) RGD PMID:15071095 MGI:3588743 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3588743|PMID:15071095)
GO_REF:0000107
RGD
Ensembl
PMID:15071095 GO_REF:0000107 MGI:3588743 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO
IEA
MGI:1857091 (MGI:3612827|PMID:16244655)
GO_REF:0000107
RGD
Ensembl
PMID:16244655 GO_REF:0000107 MGI:3612827 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857
JBrowse link
G Zpr1 ZPR1 zinc finger involved_in ISO (MGI:3575865|PMID:15767679) RGD PMID:15767679 MGI:3575865 NCBI chr 8:46,564,898...46,574,719
Ensembl chr 8:46,565,146...46,574,719
JBrowse link
positive regulation of motor neuron apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin acts_upstream_of_or_within ISO MGI:1929777 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:3580738|PMID:15944391), (MGI:3695831|PMID:17192424) RGD PMID:15944391 PMID:17192424 MGI:3580738 MGI:3695831 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Musk muscle associated receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1929066 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932
JBrowse link
G Rapsn receptor-associated protein of the synapse acts_upstream_of_or_within ISO MGI:2148091 (MGI:2137500|PMID:11312299) RGD PMID:11312299 MGI:2137500 NCBI chr 3:77,015,073...77,024,378
Ensembl chr 3:76,983,471...77,024,373
JBrowse link
regulation of motor neuron apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in IDA PMID:19077057 UniProt PMID:19077057 RGD:10047372 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:4948950 (MGI:5605640|PMID:25100604)
GO_REF:0000107
RGD
Ensembl
PMID:25100604 GO_REF:0000107 MGI:5605640 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Mir124-1 microRNA 124-1 acts_upstream_of_or_within ISO MGI:5307015|MGI:5307017 (MGI:5303045|PMID:21857657) RGD PMID:21857657 MGI:5303045 NCBI chr15:38,842,014...38,842,098
Ensembl chr15:38,842,014...38,842,098
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    cellular process 18797
      cell death 2198
        programmed cell death 2198
          apoptotic process 2117
            neuron apoptotic process 401
              motor neuron apoptotic process 27
                negative regulation of motor neuron apoptotic process 12
                positive regulation of motor neuron apoptotic process 4
                regulation of motor neuron apoptotic process + 19
paths to the root