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ONTOLOGY REPORT - ANNOTATIONS

Term:mature conventional dendritic cell differentiation
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Accession:GO:0097029 term browser browse the term
Definition:The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
Comment:Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.


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mature conventional dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:16478888)
GO_REF:0000024
(MGI:4839888|PMID:19845798)		 RGD
UniProt		 PMID:16478888 PMID:19845798 GO_REF:0000024 MGI:4839888 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:25754930) RGD PMID:25754930 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Prtn3 proteinase 3 involved_in ISO (PMID:16478888) RGD PMID:16478888 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      cellular developmental process 4768
        cell differentiation 4767
          leukocyte differentiation 676
            myeloid leukocyte differentiation 282
              mature conventional dendritic cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      cellular developmental process 4768
        cell differentiation 4767
          cell development 3311
            hemopoiesis 1064
              leukocyte differentiation 676
                mononuclear cell differentiation 545
                  dendritic cell differentiation 50
                    mature conventional dendritic cell differentiation 5
paths to the root