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ONTOLOGY REPORT - ANNOTATIONS

Term:site of DNA damage
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Accession:GO:0090734 term browser browse the term
Definition:A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
Synonyms:xref: Wikipedia:DNA_repair


show annotations for term's descendants           Sort by:
site of DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprs ADP-ribosylserine hydrolase located_in ISO (PMID:30045870) RGD PMID:30045870 NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296 		JBrowse link
G Aplf aprataxin and PNKP like factor located_in ISO (PMID:21211722) RGD PMID:21211722 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Aunip aurora kinase A and ninein interacting protein located_in ISO
ISS		 (PMID:29042561)
GO_REF:0000024		 RGD
UniProt		 PMID:29042561 GO_REF:0000024 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501 		JBrowse link
G Cbx1 chromobox 1 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096 		JBrowse link
G Cbx3 chromobox 3 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 		JBrowse link
G Cbx5 chromobox 5 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 located_in IEA
ISO		 GO_REF:0000107
(PMID:25593309)		 Ensembl
RGD		 PMID:25593309 GO_REF:0000107 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Cul5 cullin 5 located_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:28292928)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:28292928 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 is_active_in ISO (PMID:19109893) RGD PMID:19109893 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Eloa elongin A located_in IDA PMID:28292928 UniProt PMID:28292928 RGD:14929206 NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor located_in ISO (PMID:28292928) RGD PMID:28292928 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 located_in ISO (PMID:31255466) RGD PMID:31255466 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442 		JBrowse link
G H2ax H2A.X variant histone located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Helq helicase, POLQ-like is_active_in ISO (PMID:34937945) RGD PMID:34937945 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Hpf1 histone PARylation factor 1 located_in ISO (PMID:32939087) RGD PMID:32939087 NCBI chr16:29,203,749...29,219,651
Ensembl chr16:29,183,256...29,219,716 		JBrowse link
G Hrob homologous recombination factor with OB-fold located_in ISO
ISS
IEA		 (PMID:31467087)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:31467087 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,206,017...87,222,483
Ensembl chr10:87,206,049...87,222,483 		JBrowse link
G Kat7 lysine acetyltransferase 7 located_in ISO
ISS		 (PMID:28719581)
GO_REF:0000024		 RGD
UniProt		 PMID:28719581 GO_REF:0000024 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567 		JBrowse link
G Mms22l MMS22-like, DNA repair protein is_active_in ISO (PMID:27797818) RGD PMID:27797818 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745 		JBrowse link
G Nkx3-1 NK3 homeobox 1 located_in ISO (PMID:20395202) RGD PMID:20395202 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Oard1 O-acyl-ADP-ribose deacylase 1 located_in ISO (PMID:23481255) RGD PMID:23481255 NCBI chr 9:12,576,894...12,587,264
Ensembl chr 9:12,578,970...12,587,249 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 located_in
is_active_in		 ISO
ISS		 (PMID:27248496)
GO_REF:0000024
(PMID:22683995), (PMID:26626479), (PMID:26626480), (PMID:30675909), (PMID:32241924), (PMID:32358582), (PMID:34795260)
(MGI:5448491|PMID:22736760)		 RGD
UniProt		 PMID:22683995 PMID:22736760 PMID:26626479 PMID:26626480 PMID:27248496 More... GO_REF:0000024 MGI:5448491 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 located_in
is_active_in		 ISO (PMID:26704974), (PMID:32939087)
(PMID:30104678)		 RGD PMID:26704974 PMID:30104678 PMID:32939087 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 located_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Polk DNA polymerase kappa colocalizes_with ISO (PMID:28297716) RGD PMID:28297716 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 located_in ISO (PMID:28575657), (PMID:28575658) RGD PMID:28575657 PMID:28575658 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rpa1 replication protein A1 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Sirt6 sirtuin 6 is_active_in ISO (PMID:19109893) RGD PMID:19109893 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slfn13 schlafen family member 13 located_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Spindoc spindlin interactor and repressor of chromatin binding is_active_in ISO (PMID:34737271) RGD PMID:34737271 NCBI chr 1:204,541,647...204,565,109
Ensembl chr 1:204,542,335...204,564,144 		JBrowse link
G Traip TRAF-interacting protein located_in
is_active_in		 ISO
IBA		 (PMID:26711499), (PMID:30165463)
PMID:21873635		 RGD PMID:26711499 PMID:30165463 PMID:21873635 RGD:13792537 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638 		JBrowse link
G Ubqln4 ubiquilin 4 located_in ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059 		JBrowse link
G Wdr76 WD repeat domain 76 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor is_active_in ISO (MGI:5427285|PMID:22431748) RGD PMID:22431748 MGI:5427285 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 is_active_in ISO (PMID:14500814), (PMID:34102106), (PMID:34811483) RGD PMID:14500814 PMID:34102106 PMID:34811483 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 located_in ISO (PMID:27248496) RGD PMID:27248496 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 located_in ISO (PMID:25593309) RGD PMID:25593309 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463 		JBrowse link
site of double-strand break term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Actr2 actin related protein 2 located_in ISO
ISS		 (PMID:29925947)
GO_REF:0000024		 RGD
UniProt		 PMID:29925947 GO_REF:0000024 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Actr3 actin related protein 3 located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Aplf aprataxin and PNKP like factor is_active_in
located_in		 IBA
ISO		 PMID:21873635
(PMID:23689425)
(PMID:21211721)		 RGD PMID:21211721 PMID:23689425 PMID:21873635 RGD:13792537 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Atf2 activating transcription factor 2 located_in ISS
ISO		 GO_REF:0000024
(MGI:5882896|PMID:15916964)
(PMID:15916964)		 UniProt
RGD		 PMID:15916964 GO_REF:0000024 MGI:5882896 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Brme1 break repair meiotic recombinase recruitment factor 1 is_active_in ISO (MGI:6443349|PMID:32463460) RGD PMID:32463460 MGI:6443349 NCBI chr19:23,990,049...24,011,774
Ensembl chr19:23,990,045...24,011,850 		JBrowse link
G Cgas cyclic GMP-AMP synthase located_in
is_active_in		 ISO
IBA		 (PMID:30356214)
PMID:21873635		 RGD PMID:30356214 PMID:21873635 RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like is_active_in ISO (PMID:29220652), (PMID:29220653) RGD PMID:29220652 PMID:29220653 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Cyren cell cycle regulator of NHEJ is_active_in ISO
ISS		 (MGI:6202149|PMID:30017584)
GO_REF:0000024		 RGD
UniProt		 PMID:30017584 GO_REF:0000024 MGI:6202149 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Dmc1 DNA meiotic recombinase 1 is_active_in ISO (MGI:6283956|PMID:30760716), (MGI:6443349|PMID:32463460) RGD PMID:30760716 PMID:32463460 MGI:6283956 MGI:6443349 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 located_in ISO (MGI:5465053|PMID:22699483), (MGI:5493398|PMID:22614755) RGD PMID:22614755 PMID:22699483 MGI:5465053 MGI:5493398 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Fh fumarate hydratase located_in ISO (PMID:26237645) RGD PMID:26237645 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G H2ax H2A.X variant histone located_in ISO (MGI:5465053|PMID:22699483), (MGI:5470363|PMID:23133398)
(PMID:21270334)		 RGD PMID:21270334 PMID:22699483 PMID:23133398 MGI:5465053 MGI:5470363 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Helb DNA helicase B located_in ISO (PMID:26774285) RGD PMID:26774285 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Hus1 HUS1 checkpoint clamp component is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Iffo1 intermediate filament family orphan 1 located_in ISO (PMID:31548606) RGD PMID:31548606 NCBI chr 4:157,945,075...157,962,302
Ensembl chr 4:157,945,107...157,962,302 		JBrowse link
G Inip INTS3 and NABP interacting protein located_in ISO (PMID:19683501) RGD PMID:19683501 NCBI chr 5:74,648,392...74,662,628
Ensembl chr 5:74,648,392...74,662,628 		JBrowse link
G Ints3 integrator complex subunit 3 located_in ISO (PMID:19683501) RGD PMID:19683501 NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709 		JBrowse link
G Kdm4d lysine demethylase 4D located_in ISO (MGI:5552986|PMID:24550317)
(PMID:24550317)		 RGD PMID:24550317 MGI:5552986 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Lmna lamin A/C located_in ISO
IEA
ISS		 (PMID:31548606)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31548606 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G LOC100362927 replication protein A3-like is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G LOC102557137 E3 ubiquitin-protein ligase RNF168-like is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:40,065,873...40,067,029
Ensembl chr  X:40,065,873...40,067,207 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease located_in
is_active_in		 ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:15916964), (PMID:30612738)		 UniProt
Ensembl
RGD		 PMID:15916964 PMID:30612738 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nabp1 nucleic acid binding protein 1 located_in ISO (PMID:19683501) RGD PMID:19683501 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107 		JBrowse link
G Nabp2 nucleic acid binding protein 2 located_in ISO
IEA		 (PMID:19683501)
GO_REF:0000107		 RGD
Ensembl		 PMID:19683501 GO_REF:0000107 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Nbn nibrin located_in IEA
ISO		 GO_REF:0000107
(PMID:15916964)		 Ensembl
RGD		 PMID:15916964 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nhej1 nonhomologous end-joining factor 1 is_active_in ISO
ISS		 (PMID:18064046), (PMID:18644470), (PMID:27437582), (PMID:28500754)
GO_REF:0000024		 RGD
UniProt		 PMID:18064046 PMID:18644470 PMID:27437582 PMID:28500754 GO_REF:0000024 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 located_in
is_active_in		 ISO
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000024
(PMID:29234005)
(PMID:26344098), (PMID:27568560), (PMID:30356214)		 RGD
UniProt		 PMID:26344098 PMID:27568560 PMID:29234005 PMID:30356214 GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 located_in
is_active_in		 ISO
IBA		 (MGI:4947917|PMID:21270334)
(PMID:21270334)
PMID:21873635		 RGD PMID:21270334 PMID:21873635 MGI:4947917, RGD:13792537 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
G Paxx PAXX, non-homologous end joining factor located_in
is_active_in		 ISO
IBA		 (PMID:25670504)
PMID:21873635		 RGD PMID:25670504 PMID:21873635 RGD:13792537 NCBI chr 3:8,274,762...8,276,338
Ensembl chr 3:8,274,762...8,276,521 		JBrowse link
G Phf1 PHD finger protein 1 located_in ISO (PMID:23142980) RGD PMID:23142980 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase is_active_in ISO (PMID:28453785)
(MGI:5780352|PMID:26774286)		 RGD PMID:26774286 PMID:28453785 MGI:5780352 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Polh DNA polymerase eta is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723 		JBrowse link
G Poll DNA polymerase lambda is_active_in ISO
ISS		 (PMID:30250067)
GO_REF:0000024		 RGD
UniProt		 PMID:30250067 GO_REF:0000024 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 located_in ISS
ISO		 GO_REF:0000024
(PMID:18263876)		 UniProt
RGD		 PMID:18263876 GO_REF:0000024 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase located_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069 		JBrowse link
G Rad50 RAD50 double strand break repair protein located_in ISO
IEA		 (PMID:15916964)
GO_REF:0000107		 RGD
Ensembl		 PMID:15916964 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad51 RAD51 recombinase located_in
is_active_in		 ISO (PMID:24550317)
(MGI:6283956|PMID:30760716), (MGI:6443349|PMID:32463460)		 RGD PMID:24550317 PMID:30760716 PMID:32463460 MGI:6283956 MGI:6443349 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 colocalizes_with ISO (PMID:21504906) RGD PMID:21504906 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rif1 replication timing regulatory factor 1 located_in ISO (PMID:28241136)
(MGI:5468036|PMID:23306439), (MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)		 RGD PMID:23306437 PMID:23306439 PMID:23333305 PMID:28241136 MGI:5468036 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Rnf138 ring finger protein 138 located_in
is_active_in		 ISO
IBA
ISS		 (PMID:26502055), (PMID:26502057)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:26502055 PMID:26502057 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930 		JBrowse link
G Rnf138l1 ring finger protein 138 like 1 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613 		JBrowse link
G Rnf168 ring finger protein 168 located_in
is_active_in		 ISO
IBA
ISS		 (PMID:19500350), (PMID:21041483)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:19500350 PMID:21041483 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:68,486,313...68,508,296
Ensembl chr11:68,486,321...68,508,277 		JBrowse link
G Rnf169 ring finger protein 169 located_in
is_active_in		 ISO
IBA		 (PMID:22492721), (PMID:22733822), (PMID:22742833)
PMID:21873635		 RGD PMID:22492721 PMID:22733822 PMID:22742833 PMID:21873635 RGD:13792537 NCBI chr 1:154,250,462...154,311,867
Ensembl chr 1:154,254,473...154,311,653 		JBrowse link
G Rnf8 ring finger protein 8 located_in
is_active_in		 ISO
IBA
ISS		 (PMID:22266820)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:22266820 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Rpa2 replication protein A2 colocalizes_with
is_active_in		 ISO
IBA
ISS		 (PMID:21504906)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:21504906 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 located_in ISO (PMID:28834754), (PMID:29670289) RGD PMID:28834754 PMID:29670289 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene located_in ISO (PMID:18263876), (PMID:21187428), (PMID:22231448) RGD PMID:18263876 PMID:21187428 PMID:22231448 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
G Shld1 shieldin complex subunit 1 located_in
is_active_in		 ISO
IBA		 (PMID:29656893)
PMID:21873635		 RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550 		JBrowse link
G Shld2 shieldin complex subunit 2 located_in
is_active_in		 ISO
IBA		 (PMID:29656893)
PMID:21873635		 RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Shld3 shieldin complex subunit 3 located_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865
Ensembl chr 2:35,295,859...35,302,346 		JBrowse link
G Sirt6 sirtuin 6 is_active_in ISO (PMID:21680843), (PMID:23911928), (PMID:27568560), (PMID:31995034), (PMID:32538779) RGD PMID:21680843 PMID:23911928 PMID:27568560 PMID:31995034 PMID:32538779 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 located_in ISS
ISO		 GO_REF:0000024
(MGI:5789069|PMID:27225932)
(PMID:27436229)		 UniProt
RGD		 PMID:27225932 PMID:27436229 GO_REF:0000024 MGI:5789069 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 located_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 located_in
is_active_in		 ISO
IBA		 (PMID:25931565)
PMID:21873635		 RGD PMID:25931565 PMID:21873635 RGD:13792537 NCBI chr 1:243,782,781...243,845,409
Ensembl chr 1:243,782,246...243,845,250 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 is_active_in ISO (PMID:23911928) RGD PMID:23911928 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` located_in ISO
ISS		 (PMID:22960744)
GO_REF:0000024		 RGD
UniProt		 PMID:22960744 GO_REF:0000024 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563 		JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 located_in ISS
ISO		 GO_REF:0000024
(PMID:19793862), (PMID:19793863)		 UniProt
RGD		 PMID:19793862 PMID:19793863 GO_REF:0000024 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 located_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 located_in
is_active_in		 ISO
IBA		 (PMID:25931565)
PMID:21873635		 RGD PMID:25931565 PMID:21873635 RGD:13792537 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 located_in ISO (PMID:24790221), (PMID:25294876) RGD PMID:24790221 PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665 		JBrowse link
G Timeless timeless circadian regulator located_in ISO
IEA
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein is_active_in ISS
ISO		 GO_REF:0000024
(PMID:26527279), (PMID:27338793), (PMID:29478807)		 UniProt
RGD		 PMID:26527279 PMID:27338793 PMID:29478807 GO_REF:0000024 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Tp53 tumor protein p53 located_in ISO (MGI:5552986|PMID:24550317) RGD PMID:24550317 MGI:5552986 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 located_in ISO (PMID:23333306), (PMID:23760478), (PMID:28241136)
(MGI:5476381|PMID:23333305), (MGI:5887191|PMID:23209566)		 RGD PMID:23209566 PMID:23333305 PMID:23333306 PMID:23760478 PMID:28241136 MGI:5476381 MGI:5887191 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 located_in ISO
ISS		 (PMID:30886146)
GO_REF:0000024		 RGD
UniProt		 PMID:30886146 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Vcp valosin-containing protein located_in ISO
ISS		 (PMID:22120668)
GO_REF:0000024		 RGD
UniProt		 PMID:22120668 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Was WASP actin nucleation promoting factor located_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:14,405,096...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Wdr70 WD repeat domain 70 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:56,951,345...57,191,244
Ensembl chr 2:56,951,355...57,191,187 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 located_in ISO
ISS		 (PMID:25512560), (PMID:26734725), (PMID:27715493)
GO_REF:0000024		 RGD
UniProt		 PMID:25512560 PMID:26734725 PMID:27715493 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 located_in
part_of
is_active_in		 ISO (PMID:31548606)
(PMID:27644316)
(PMID:26774286), (PMID:27437582), (PMID:28500754)		 RGD PMID:26774286 PMID:27437582 PMID:27644316 PMID:28500754 PMID:31548606 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a colocalizes_with
located_in		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5702356|PMID:26446488)		 UniProt
Ensembl
RGD		 PMID:26446488 GO_REF:0000024 GO_REF:0000107 MGI:5702356 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20532
    cellular anatomical entity 20289
      site of DNA damage 109
        site of double-strand break 78
Path 2
Term Annotations click to browse term
  cellular_component 20532
    cellular anatomical entity 20289
      organelle 13524
        non-membrane-bounded organelle 5113
          intracellular non-membrane-bounded organelle 5112
            chromosome 1322
              site of DNA damage 109
                site of double-strand break 78
paths to the root