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Term:Las1 complex
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Accession:GO:0090730 term browser browse the term
Definition:A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).
Synonyms:narrow_synonym: Las1-Grc3-Rat1-Rai1

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Las1 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Las1l LAS1-like, ribosome biogenesis factor IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:65,081,591...65,102,344
Ensembl chr  X:65,081,591...65,102,380
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      cytosol 4165
        Las1 complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      catalytic complex 1487
        transferase complex 818
          transferase complex, transferring phosphorus-containing groups 266
            protein kinase complex 106
              Las1 complex 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.