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Term:cerebrospinal fluid circulation
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Accession:GO:0090660 term browser browse the term
Definition:The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.
Synonyms:exact_synonym: CSF circulation;   CSF flow;   cerebrospinal fluid flow

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cerebrospinal fluid circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 involved_in ISS
PMID:22896675 GO_REF:0000024 MGI:5435611 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit acts_upstream_of_or_within ISO MGI:4364215|MGI:5056368|MGI:5316786 (MGI:5050793|PMID:21515572), (MGI:6111002|PMID:29317443), (MGI:6161988|PMID:28289722) RGD PMID:21515572 PMID:28289722 PMID:29317443 MGI:5050793 MGI:6111002 MGI:6161988 NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350
JBrowse link
G Cfap221 cilia and flagella associated protein 221 acts_upstream_of_or_within ISO MGI:1922208|MGI:2443727|MGI:3608909 (MGI:3771635|PMID:18039845), (MGI:6453448|PMID:32704025) RGD PMID:18039845 PMID:32704025 MGI:3771635 MGI:6453448 NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899
JBrowse link
G Cfap43 cilia and flagella associated protein 43 acts_upstream_of_or_within ISO MGI:6431400 (MGI:6402702|PMID:31884020) RGD PMID:31884020 MGI:6402702 NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443
JBrowse link
G Cfap45 cilia and flagella associated protein 45 acts_upstream_of_or_within ISO MGI:6509073 (MGI:6479264|PMID:33139725) RGD PMID:33139725 MGI:6479264 NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878
JBrowse link
G Cfap53 cilia and flagella associated protein 53 acts_upstream_of_or_within ISO MGI:6720857 (MGI:6503922|PMID:33347437) RGD PMID:33347437 MGI:6503922 NCBI chr18:67,884,651...67,955,873
Ensembl chr18:67,869,855...67,952,318
JBrowse link
G Cfap54 cilia and flagella associated protein 54 acts_upstream_of_or_within ISO MGI:2443727|MGI:2684947 (MGI:6453448|PMID:32704025) RGD PMID:32704025 MGI:6453448 NCBI chr 7:27,316,498...27,601,630
Ensembl chr 7:27,316,502...27,602,144
JBrowse link
G Daw1 dynein assembly factor with WD repeats 1 acts_upstream_of_or_within
MGI:5431501 (MGI:6161988|PMID:28289722)
PMID:28289722 GO_REF:0000107 MGI:6161988 NCBI chr 9:84,435,552...84,472,632
Ensembl chr 9:84,435,552...84,472,635
JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 acts_upstream_of_or_within ISO MGI:6147714 (MGI:6147712|PMID:27353389) RGD PMID:27353389 MGI:6147712 NCBI chr 7:98,141,525...98,245,906
Ensembl chr 7:98,144,763...98,245,837
JBrowse link
G Dnah9 dynein, axonemal, heavy chain 9 acts_upstream_of_or_within ISO MGI:6720876 (MGI:6503922|PMID:33347437) RGD PMID:33347437 MGI:6503922 NCBI chr10:50,496,174...50,864,909
Ensembl chr10:50,497,688...50,864,949
JBrowse link
G Jhy junctional cadherin complex regulator acts_upstream_of_or_within ISO MGI:5437647 (MGI:5517715|PMID:23906841), (MGI:6103256|PMID:29211732) RGD PMID:23906841 PMID:29211732 MGI:5517715 MGI:6103256 NCBI chr 8:41,276,501...41,333,383
Ensembl chr 8:41,276,491...41,333,514
JBrowse link
G Katnip katanin interacting protein acts_upstream_of_or_within ISO MGI:4128978 (MGI:5882164|PMID:26714646) RGD PMID:26714646 MGI:5882164 NCBI chr 1:180,270,194...180,436,766
Ensembl chr 1:180,269,929...180,436,766
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 acts_upstream_of_or_within ISO (MGI:5913033|PMID:28392297), (MGI:6393053|PMID:25775275) RGD PMID:25775275 PMID:28392297 MGI:5913033 MGI:6393053 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Odad3 outer dynein arm docking complex subunit 3 acts_upstream_of_or_within ISO MGI:5548687 (MGI:6360364|PMID:31383820) RGD PMID:31383820 MGI:6360364 NCBI chr 8:20,520,898...20,534,499
Ensembl chr 8:20,520,898...20,534,499
JBrowse link
G Odad4 outer dynein arm docking complex subunit 4 acts_upstream_of_or_within ISO MGI:6110171 (MGI:5913140|PMID:27486780) RGD PMID:27486780 MGI:5913140 NCBI chr10:85,480,089...85,508,603
Ensembl chr10:85,480,094...85,508,603
JBrowse link
G Spag16 sperm associated antigen 16 acts_upstream_of_or_within ISO MGI:1354388 (MGI:6274126|PMID:17323374) RGD PMID:17323374 MGI:6274126 NCBI chr 9:71,333,005...72,252,772
Ensembl chr 9:71,332,992...72,252,708
JBrowse link
G Spag6l sperm associated antigen 6-like acts_upstream_of_or_within ISO MGI:1913972|MGI:2662475 (MGI:5691632|PMID:25393619), (MGI:6274126|PMID:17323374) RGD PMID:17323374 PMID:25393619 MGI:5691632 MGI:6274126 NCBI chr11:84,173,628...84,269,374
Ensembl chr11:84,173,526...84,269,364
JBrowse link
G Spef2 sperm flagellar 2 acts_upstream_of_or_within ISO MGI:1922208|MGI:2684947 (MGI:6453448|PMID:32704025) RGD PMID:32704025 MGI:6453448 NCBI chr 2:58,512,489...58,694,718
Ensembl chr 2:58,512,489...58,694,664
JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO MGI:4362969 (MGI:5790513|PMID:27445138) RGD PMID:27445138 MGI:5790513 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20350
    multicellular organismal process 9315
      system process 3526
        nervous system process 2734
          cerebrospinal fluid circulation 19
Path 2
Term Annotations click to browse term
  biological_process 20350
    cellular process 18813
      microtubule-based process 1052
        microtubule-based movement 466
          cilium movement 240
            epithelial cilium movement involved in extracellular fluid movement 45
              cerebrospinal fluid circulation 19
paths to the root