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ONTOLOGY REPORT - ANNOTATIONS


Term:endoribonuclease activity, cleaving miRNA-paired mRNA
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Accession:GO:0090624 term browser browse the term
Definition:Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.


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endoribonuclease activity, cleaving miRNA-paired mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
RGD:1624291
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      catalytic activity, acting on RNA 357
        ribonuclease activity 121
          endoribonuclease activity 63
            endoribonuclease activity, producing 5'-phosphomonoesters 28
              endoribonuclease activity, cleaving miRNA-paired mRNA 2
Path 2
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 782
          nuclease activity 212
            endonuclease activity 121
              endoribonuclease activity 63
                endoribonuclease activity, producing 5'-phosphomonoesters 28
                  endoribonuclease activity, cleaving miRNA-paired mRNA 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.