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ONTOLOGY REPORT - ANNOTATIONS

Term:oncogene-induced cell senescence
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Accession:GO:0090402 term browser browse the term
Definition:A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.
Synonyms:exact_synonym: OIS


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oncogene-induced cell senescence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:104738|MGI:1933751 (PMID:11551927) RGD PMID:11551927 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of_or_within ISO MGI:104556|MGI:1857942 (PMID:11551927) RGD PMID:11551927 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Hmga1 high mobility group AT-hook 1 involved_in ISO
ISS		 (PMID:16901784)
GO_REF:0000024		 RGD
UniProt		 PMID:16901784 GO_REF:0000024 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16901784)		 UniProt
RGD		 PMID:16901784 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:11551927) RGD PMID:11551927 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3717518|PMID:10910364) RGD PMID:10910364 MGI:3717518 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6478061|PMID:28912174) RGD PMID:28912174 MGI:6478061 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      cellular metabolic process 10279
        cellular senescence 108
          oncogene-induced cell senescence 7
Path 2
Term Annotations click to browse term
  biological_process 20292
    response to stimulus 10871
      response to stress 4259
        cellular response to stress 2047
          cellular senescence 108
            oncogene-induced cell senescence 7
paths to the root