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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol efflux
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Accession:GO:0090370 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.



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negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) UniProt PMID:19752193 MGI:4411947 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860
JBrowse link
G LOC110259864 group 10 secretory phospholipase A2-like involved_in ISO (MGI:5051938|PMID:20844270) BHF-UCL PMID:20844270 MGI:5051938 NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,312...7,642,002
JBrowse link
G MIR128-1 microRNA mir-128-1 involved_in
acts_upstream_of
ISO (PMID:26501192)
(PMID:23990020)
BHF-UCL PMID:23990020 PMID:26501192 NCBI chr15:16,273,557...16,273,638
Ensembl chr15:16,273,551...16,273,659
JBrowse link
G MIR128-2 microRNA mir-128-2 acts_upstream_of
involved_in
ISO (PMID:23990020)
(PMID:26501192)
BHF-UCL PMID:23990020 PMID:26501192 NCBI chr13:21,038,445...21,038,524
Ensembl chr13:21,038,442...21,038,525
JBrowse link
G MIR130B microRNA mir-130b involved_in ISO (PMID:26501192) BHF-UCL PMID:26501192 NCBI chr14:50,245,041...50,245,120
Ensembl chr14:50,245,041...50,245,120
JBrowse link
G MIR144 microRNA mir-144 involved_in ISO (PMID:23519695)
(PMID:24733347)
BHF-UCL
ARUK-UCL
PMID:23519695 PMID:24733347 NCBI chr12:45,088,958...45,089,033
Ensembl chr12:45,088,959...45,089,035
JBrowse link
G MIR148A microRNA mir-148a involved_in ISO (PMID:26437365), (PMID:26501192) BHF-UCL PMID:26437365 PMID:26501192 NCBI chr18:46,415,213...46,415,280
Ensembl chr18:46,415,202...46,415,281
JBrowse link
G MIR19B-1 microRNA mir-19b-1 involved_in ISO (PMID:25084135)
(PMID:25765596)
BHF-UCL PMID:25084135 PMID:25765596 NCBI chr11:60,735,238...60,735,317
Ensembl chr11:60,735,230...60,735,328
JBrowse link
G MIR19B-2 microRNA mir-19b-2 involved_in ISO (PMID:25084135)
(PMID:25765596)
BHF-UCL PMID:25084135 PMID:25765596 NCBI chr  X:110,113,855...110,113,934
Ensembl chr  X:110,113,855...110,113,934
JBrowse link
G MIR206 microRNA mir-206 acts_upstream_of ISO (PMID:24603323) BHF-UCL PMID:24603323 NCBI chr 7:45,976,293...45,976,372
Ensembl chr 7:45,976,293...45,976,372
JBrowse link
G MIR27A microRNA mir-27a involved_in ISO (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr 2:65,308,294...65,308,375
Ensembl chr 2:65,308,294...65,308,375
JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:24608080), (PMID:26520906) ARUK-UCL PMID:24608080 PMID:26520906 NCBI chr10:27,079,963...27,080,042
Ensembl chr10:27,079,954...27,080,056
JBrowse link
G MIR9-1 microRNA mir-9-1 involved_in ISO (PMID:29584810) BHF-UCL PMID:29584810 NCBI chr 4:93,660,422...93,660,510 JBrowse link
G MIR9-2 microRNA mir-9-2 involved_in ISO (PMID:29584810) BHF-UCL PMID:29584810 NCBI chr 2:96,076,352...96,076,438 JBrowse link
G MIR9-3 microRNA mir-9-3 involved_in ISO (PMID:29584810) BHF-UCL PMID:29584810 NCBI chr 7:54,948,452...54,948,532
Ensembl chr 7:54,948,447...54,948,536
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:15358760) Ensembl
BHF-UCL
Ensembl
PMID:15358760 GO_REF:0000107 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17339
    negative regulation of biological process 5678
      negative regulation of lipid localization 69
        negative regulation of lipid transport 53
          negative regulation of sterol transport 27
            negative regulation of cholesterol transport 27
              negative regulation of cholesterol efflux 20
Path 2
Term Annotations click to browse term
  biological_process 17339
    localization 5344
      establishment of localization 4686
        transport 4520
          organic substance transport 2416
            lipid transport 451
              sterol transport 135
                cholesterol transport 120
                  regulation of cholesterol transport 78
                    regulation of cholesterol efflux 50
                      negative regulation of cholesterol efflux 20
paths to the root