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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cell aging
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Accession:GO:0090342 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.


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negative regulation of cell aging term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxm1 forkhead box M1 involved_in ISO
IEA
(PMID:19696738)
GO_REF:0000107
RGD
Ensembl
PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (MGI:5009768|PMID:21241890) RGD PMID:21241890 MGI:5009768 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:20103533) RGD PMID:20103533 NCBI chr 1:234,931,137...234,953,849
Ensembl chr 1:234,931,271...234,952,632
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:10562313) RGD PMID:10562313 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:5009768|PMID:21241890) RGD PMID:21241890 MGI:5009768 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
negative regulation of cellular senescence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Akt3 AKT serine/threonine kinase 3 involved_in ISO
IEA
(PMID:25323119)
GO_REF:0000107
RGD
Ensembl
PMID:25323119 GO_REF:0000107 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Bcl2l12 BCL2 like 12 acts_upstream_of_or_within ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:5469797|PMID:23209284) RGD PMID:23209284 MGI:5469797 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:17420273) RGD PMID:17420273 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO (MGI:5582375|PMID:23072816) RGD PMID:23072816 MGI:5582375 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G LOC100912427 nuclease-sensitive element-binding protein 1-like involved_in ISO (MGI:6158172|PMID:29712925) RGD PMID:29712925 MGI:6158172 NCBI chr 1:171,304,587...171,306,092
Ensembl chr 1:171,304,774...171,306,097
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 involved_in ISO (PMID:28640956) RGD PMID:28640956 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IDA RGD PMID:28125705 RGD:13781884 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISO (MGI:6120300|PMID:27908889) RGD PMID:27908889 MGI:6120300 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 involved_in ISO (PMID:28595801) RGD PMID:28595801 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(PMID:20203304), (PMID:20424141)
GO_REF:0000107
RGD
Ensembl
PMID:20203304 PMID:20424141 GO_REF:0000107 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc30a10 solute carrier family 30, member 10 involved_in ISO (PMID:22427991) RGD PMID:22427991 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:11313459), (PMID:11927518) RGD PMID:11313459 PMID:11927518 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tp63 tumor protein p63 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Ybx1 Y box binding protein 1 involved_in IEA
ISS
GO_REF:0000107
GO_REF:0000024
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:43,217,168...43,232,828
Ensembl chr17:43,217,222...43,232,827
JBrowse link
positive regulation of cell aging term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmna lamin A/C involved_in ISO
IEA
ISS
(PMID:20458013)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20458013 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (MGI:5142390|PMID:10562313) RGD PMID:10562313 MGI:5142390 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of cellular senescence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO (PMID:21223585) RGD PMID:21223585 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
JBrowse link
G Abi3bp ABI family member 3 binding protein involved_in ISS GO_REF:0000024 ARUK-UCL GO_REF:0000024 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
JBrowse link
G Arg2 arginase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22928666)
Ensembl
RGD
PMID:22928666 GO_REF:0000107 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G B2m beta-2 microglobulin involved_in ISO (PMID:28213472) RGD PMID:28213472 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:16901784) RGD PMID:16901784 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (MGI:5909142|PMID:28759028) RGD PMID:28759028 MGI:5909142 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 involved_in ISO (PMID:25465621) RGD PMID:25465621 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Hmga1 high mobility group AT-hook 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16901784)
UniProt
RGD
PMID:16901784 GO_REF:0000024 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS
(PMID:16901784)
GO_REF:0000024
RGD
UniProt
PMID:16901784 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:17706954 RGD:11060281 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Pawr pro-apoptotic WT1 regulator involved_in IEA
ISO
GO_REF:0000107
(MGI:5648604|PMID:25472717)
Ensembl
RGD
PMID:25472717 GO_REF:0000107 MGI:5648604 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:18687677)
Ensembl
RGD
PMID:18687677 GO_REF:0000107 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (PMID:20203304) RGD PMID:20203304 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Ypel3 yippee-like 3 involved_in ISO (PMID:20388804) RGD PMID:20388804 NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
JBrowse link
regulation of cellular senescence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1338938 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO
GO_REF:0000024
(MGI:5554364|PMID:22101268)
UniProt
RGD
PMID:22101268 GO_REF:0000024 MGI:5554364 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:87859 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO MGI:1890508 (MGI:5500993|PMID:23686339) RGD PMID:23686339 MGI:5500993 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128
JBrowse link
G Ing2 inhibitor of growth family, member 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Nek4 NIMA-related kinase 4 involved_in ISO (PMID:22851694) RGD PMID:22851694 NCBI chr16:6,144,900...6,185,376
Ensembl chr16:6,144,959...6,188,932
JBrowse link
G Nuak1 NUAK family kinase 1 involved_in ISO (PMID:19927127) RGD PMID:19927127 NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:16055741) RGD PMID:16055741 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696
JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 involved_in ISO (PMID:18678645) RGD PMID:18678645 NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:2445449 (MGI:5913114|PMID:23695662) RGD PMID:23695662 MGI:5913114 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:2139971 (MGI:5504576|PMID:22904064) RGD PMID:22904064 MGI:5504576 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vash1 vasohibin 1 acts_upstream_of_or_within ISO (PMID:23056314) RGD PMID:23056314 NCBI chr 6:106,330,374...106,345,740
Ensembl chr 6:106,329,123...106,345,726
JBrowse link
G Zfp277 zinc finger protein 277 acts_upstream_of_or_within ISO MGI:5496522 (MGI:5496352|PMID:20808772) RGD PMID:20808772 MGI:5496352 NCBI chr 6:57,383,944...57,512,785
Ensembl chr 6:57,383,951...57,512,765
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:1888594|MGI:2180033 (MGI:3789238|PMID:16079796), (MGI:5139938|PMID:21746928), (MGI:5500993|PMID:23686339) RGD PMID:16079796 PMID:21746928 PMID:23686339 MGI:3789238 MGI:5139938 MGI:5500993 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    regulation of biological process 12769
      regulation of developmental process 2663
        regulation of cell aging 53
          negative regulation of cell aging + 27
          positive regulation of cell aging + 16
          regulation of cellular senescence + 46
          regulation of replicative senescence + 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      cellular developmental process 4478
        cell aging 155
          regulation of cell aging 53
            negative regulation of cell aging + 27
            positive regulation of cell aging + 16
            regulation of cellular senescence + 46
            regulation of replicative senescence + 0
paths to the root