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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of platelet aggregation
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Accession:GO:0090330 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


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regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936496:2,578,598...2,698,165
Ensembl chrNW_004936496:2,637,958...2,700,055
JBrowse link
G Prkca protein kinase C alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:6,231,604...6,488,201
Ensembl chrNW_004936541:6,233,110...6,488,052
JBrowse link
G Prkcq protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:8,048,239...8,166,058
Ensembl chrNW_004936484:8,048,132...8,167,636
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936780:1,553,605...1,601,036
Ensembl chrNW_004936780:1,553,605...1,598,158
JBrowse link
G Vps33b VPS33B late endosome and lysosome associated involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:16,007,448...16,031,353
Ensembl chrNW_004936483:16,007,465...16,032,392
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19218546) Ensembl
MGI
PMID:19218546 GO_REF:0000107 NCBI chrNW_004936475:25,698,117...25,831,291
Ensembl chrNW_004936475:25,699,840...25,831,284
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:3,338,863...3,358,137
Ensembl chrNW_004936594:3,338,774...3,358,985
JBrowse link
G Cd9 CD9 molecule involved_in ISO (PMID:18541721) UniProt PMID:18541721 NCBI chrNW_004936709:1,497,504...1,530,114 JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101963440 polyunsaturated fatty acid lipoxygenase ALOX12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:269,085...282,445
Ensembl chrNW_004936595:270,271...282,660
JBrowse link
G Prkcd protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:3,892,625...3,923,467
Ensembl chrNW_004936473:3,892,366...3,923,515
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936787:330,390...1,491,994
Ensembl chrNW_004936787:332,342...1,491,285
JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:5,642,328...5,668,278
Ensembl chrNW_004936569:5,642,264...5,668,323
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:4,103,898...4,126,883
Ensembl chrNW_004936558:4,104,534...4,123,869
JBrowse link
G Tmx1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:14,432,971...14,447,380
Ensembl chrNW_004936495:14,431,137...14,447,476
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20585042) Ensembl
MGI
PMID:20585042 GO_REF:0000107 NCBI chrNW_004936542:7,225,387...7,370,163
Ensembl chrNW_004936542:7,225,977...7,373,381
JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Emilin2 elastin microfibril interfacer 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936672:1,607,914...1,661,531
Ensembl chrNW_004936672:1,609,193...1,661,528
JBrowse link
G F11r F11 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:317,975...338,892
Ensembl chrNW_004936903:315,716...338,932
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:18358471 RGD:401938603 NCBI chrNW_004936565:335,238...394,683
Ensembl chrNW_004936565:334,393...394,715
JBrowse link
G Il6 interleukin 6 acts_upstream_of ISO (PMID:31145836) ARUK-UCL PMID:31145836 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Il6r interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) ARUK-UCL PMID:31145836 NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885
JBrowse link
G Jak2 Janus kinase 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:31145836) Ensembl
ARUK-UCL
PMID:31145836 GO_REF:0000107 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
JBrowse link
G LOC101959956 cathepsin G-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:34,410...37,097
Ensembl chrNW_004936722:34,392...37,097
JBrowse link
G Mfsd2b MFSD2 lysolipid transporter B, sphingolipid involved_in ISO (MGI:6713713|PMID:33863882) UniProt PMID:33863882 MGI:6713713 NCBI chrNW_004936493:7,952,623...7,959,803
Ensembl chrNW_004936493:7,951,294...7,963,317
JBrowse link
G Mmrn1 multimerin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,236,072...2,291,636
Ensembl chrNW_004936685:2,251,978...2,291,261
JBrowse link
G Pdpn podoplanin involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:1,751,159...1,779,011
Ensembl chrNW_004936474:1,750,944...1,781,156
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    cellular process 15075
      cell activation 1063
        regulation of cell activation 582
          regulation of platelet activation 47
            regulation of platelet aggregation 26
              negative regulation of platelet aggregation 11
              perturbation of platelet aggregation in another organism + 0
              positive regulation of platelet aggregation 10
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological quality 2991
        regulation of body fluid levels 352
          hemostasis 182
            blood coagulation 178
              platelet activation 112
                platelet aggregation 76
                  regulation of platelet aggregation 26
                    negative regulation of platelet aggregation 11
                    perturbation of platelet aggregation in another organism + 0
                    positive regulation of platelet aggregation 10
paths to the root