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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of platelet aggregation
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Accession:GO:0090330 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


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regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G PRKCA protein kinase C alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G VPS33B VPS33B late endosome and lysosome associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,220,199...53,239,738
Ensembl chr 3:53,220,194...53,239,732 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19218546) Ensembl
MGI		 PMID:19218546 GO_REF:0000107 NCBI chr 5:73,769,462...73,907,024
Ensembl chr 5:73,772,114...73,905,264 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053 		JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in ISO (MGI:4418017|PMID:19855083) BHF-UCL PMID:19855083 MGI:4418017 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228 		JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:27,541,407...27,556,058
Ensembl chr 8:27,541,460...27,554,681 		JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20585042) Ensembl
MGI		 PMID:20585042 GO_REF:0000107 NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675 		JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSG cathepsin G involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,483,327...4,485,933
Ensembl chr 8:4,470,577...4,512,628 		JBrowse link
G EMILIN2 elastin microfibril interfacer 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,521,430...69,580,963 JBrowse link
G F11R F11 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,433,819...21,456,722
Ensembl chr38:21,451,952...21,454,959 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:18358471 RGD:401938603 NCBI chr22:4,453,715...4,510,934
Ensembl chr22:4,453,715...4,511,037 		JBrowse link
G IL6 interleukin 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31145836) Ensembl
ARUK-UCL		 PMID:31145836 GO_REF:0000107 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IL6R interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) ARUK-UCL PMID:31145836 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090 		JBrowse link
G JAK2 Janus kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31145836) Ensembl
ARUK-UCL		 PMID:31145836 GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G MFSD2B MFSD2 lysolipid transporter B, sphingolipid involved_in ISO (MGI:6713713|PMID:33863882) UniProt PMID:33863882 MGI:6713713 NCBI chr17:18,496,559...18,506,472
Ensembl chr17:18,408,251...18,505,676 		JBrowse link
G MMRN1 multimerin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:13,111,043...13,184,681
Ensembl chr32:13,110,969...13,184,649 		JBrowse link
G PDPN podoplanin involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cell activation 1169
        regulation of cell activation 639
          regulation of platelet activation 46
            regulation of platelet aggregation 26
              negative regulation of platelet aggregation 11
              perturbation of platelet aggregation in another organism + 0
              positive regulation of platelet aggregation 10
Path 2
Term Annotations click to browse term
  biological_process 17878
    biological regulation 12365
      regulation of biological quality 3298
        regulation of body fluid levels 372
          hemostasis 191
            blood coagulation 187
              platelet activation 119
                platelet aggregation 81
                  regulation of platelet aggregation 26
                    negative regulation of platelet aggregation 11
                    perturbation of platelet aggregation in another organism + 0
                    positive regulation of platelet aggregation 10
paths to the root