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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of platelet aggregation
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Accession:GO:0090330 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


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regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100992916 chymotrypsin-like elastase family member 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:14,595,218...14,606,322
Ensembl chr 1:15,589,878...15,604,926 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G PRKCA protein kinase C alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
G VPS33B VPS33B late endosome and lysosome associated involved_in ISO (MGI:5645581|PMID:25947942) UniProt PMID:25947942 MGI:5645581 NCBI chr15:69,691,717...69,715,617
Ensembl chr15:88,888,093...88,912,327 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19218546) Ensembl
MGI		 PMID:19218546 GO_REF:0000107 NCBI chr16:57,857,112...58,011,181
Ensembl chr16:77,291,148...77,445,664 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386 		JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:108,977,344...109,024,029 JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,844,418...31,861,911
Ensembl chr14:50,129,568...50,147,057 		JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20585042) Ensembl
MGI		 PMID:20585042 GO_REF:0000107 NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133 		JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSG cathepsin G involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,342,517...5,345,218
Ensembl chr14:23,466,265...23,468,960 		JBrowse link
G EMILIN2 elastin microfibril interfacer 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:11,368,328...11,435,808
Ensembl chr18:13,678,772...13,743,346 		JBrowse link
G F11R F11 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:18358471 RGD:401938603 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (PMID:31145836) ARUK-UCL PMID:31145836 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) ARUK-UCL PMID:31145836 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089 		JBrowse link
G JAK2 Janus kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31145836) Ensembl
ARUK-UCL		 PMID:31145836 GO_REF:0000107 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G MFSD2B MFSD2 lysolipid transporter B, sphingolipid involved_in ISO (MGI:6713713|PMID:33863882) UniProt PMID:33863882 MGI:6713713 NCBI chr2A:24,008,477...24,025,356
Ensembl chr2A:24,106,562...24,121,908 		JBrowse link
G MMRN1 multimerin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,132,874...82,254,343
Ensembl chr 4:92,892,824...92,974,854 		JBrowse link
G PDPN podoplanin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cell activation 1128
        regulation of cell activation 621
          regulation of platelet activation 47
            regulation of platelet aggregation 27
              negative regulation of platelet aggregation 11
              perturbation of platelet aggregation in another organism + 0
              positive regulation of platelet aggregation 10
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological quality 3071
        regulation of body fluid levels 376
          hemostasis 195
            blood coagulation 191
              platelet activation 124
                platelet aggregation 79
                  regulation of platelet aggregation 27
                    negative regulation of platelet aggregation 11
                    perturbation of platelet aggregation in another organism + 0
                    positive regulation of platelet aggregation 10
paths to the root