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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated DNA replication
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Accession:GO:0090329 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.
Synonyms:exact_synonym: regulation of DNA-dependent DNA replication



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regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,317,515...53,412,649
Ensembl chr 7:53,317,540...53,412,645
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chr 1:13,466,961...13,478,496
Ensembl chr 1:13,467,501...13,505,928
JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) ComplexPortal PMID:19906994 NCBI chr 6:893,377...897,706
Ensembl chr 6:893,381...897,934
JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,585,968...19,595,346
Ensembl chr 7:19,586,002...19,595,344
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,654
JBrowse link
G LIG3 DNA ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,153,105...40,205,077
Ensembl chr12:40,153,397...40,183,622
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2F7 E2F transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:104,126,924...104,163,582
Ensembl chr 5:104,127,731...104,163,212
JBrowse link
G E2F8 E2F transcription factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:40,178,182...40,194,932
Ensembl chr 2:40,178,177...40,194,935
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,000,688...41,009,588
Ensembl chr 3:41,000,690...41,009,589
JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,161,063...19,180,002
Ensembl chr 4:19,161,226...19,178,568
JBrowse link
G GINS1 GINS complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,060,540...31,076,807
Ensembl chr17:31,060,650...31,080,314
JBrowse link
G GINS2 GINS complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:3,218,655...3,252,740
Ensembl chr 6:3,218,702...3,243,899
JBrowse link
G GINS3 GINS complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:20,162,264...20,170,385
Ensembl chr 6:20,162,636...20,170,258
JBrowse link
G GINS4 GINS complex subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,656,869...10,668,664
Ensembl chr17:10,656,884...10,668,664
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr12:14,582,075...14,601,576
Ensembl chr12:14,582,544...14,601,570
JBrowse link
G RFC2 replication factor C subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:11,373,489...11,392,690
Ensembl chr 3:11,373,492...11,392,695
JBrowse link
G RFC3 replication factor C subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:10,145,927...10,524,472
Ensembl chr11:10,146,531...10,165,172
JBrowse link
G RFC4 replication factor C subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:124,589,292...124,604,421
Ensembl chr13:124,589,295...124,604,426
JBrowse link
G RFC5 replication factor C subunit 5 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr14:34,630,374...34,642,598
Ensembl chr14:34,629,951...34,642,585
JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chr 6:893,377...897,706
Ensembl chr 6:893,381...897,934
JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4439421|PMID:20215406) MGI
Ensembl
PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr 5:21,365,723...21,372,170
Ensembl chr 5:21,365,764...21,372,168
JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (MGI:4439421|PMID:20215406)
(MGI:3513706|PMID:15585571)
MGI PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 1:268,618,972...268,642,064
Ensembl chr 1:268,617,087...268,641,893
JBrowse link
G RAB5B RAB5B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,373,333...21,392,729
Ensembl chr 5:21,387,250...21,389,745
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:269,153,955...269,157,789
Ensembl chr 1:269,154,090...269,157,788
JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:8,084,292...8,167,983
Ensembl chr18:8,151,029...8,167,983
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) MGI PMID:2161540 MGI:79015 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,584,028...61,872,341
Ensembl chr  X:61,584,848...61,872,287
JBrowse link
G CDC7 cell division cycle 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:125,431,454...125,459,367
Ensembl chr 4:125,432,772...125,459,288
JBrowse link
G DBF4 DBF4 zinc finger involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:92,449,385...92,481,959
Ensembl chr 9:92,448,731...92,481,379
JBrowse link
G DBF4B DBF4 zinc finger B involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:18,602,218...18,640,216
Ensembl chr12:18,603,797...18,630,543
JBrowse link
G INO80 INO80 complex ATPase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,201,705...130,341,627
Ensembl chr 1:130,201,718...130,342,838
JBrowse link
G WIZ WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chr 2:62,155,387...62,181,797
Ensembl chr 2:62,155,428...62,182,769
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SENP2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chr13:123,429,915...123,469,913
Ensembl chr13:123,429,995...123,471,926
JBrowse link
regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 6:893,377...897,706
Ensembl chr 6:893,381...897,934
JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,585,968...19,595,346
Ensembl chr 7:19,586,002...19,595,344
JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chr12:25,970,966...26,005,006
Ensembl chr12:25,970,962...26,008,302
JBrowse link
G MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:34,377,130...34,386,095
Ensembl chr16:34,376,959...34,384,453
JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,142,957...55,200,259
Ensembl chr 7:55,143,240...55,200,640
JBrowse link
G WRNIP1 WRN helicase interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:1,656,952...1,667,885
Ensembl chr 7:1,656,984...1,667,879
JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:104,055,813...104,384,416
Ensembl chr 6:104,055,814...104,078,381
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3583382|PMID:15980864) MGI
Ensembl
PMID:15980864 GO_REF:0000107 MGI:3583382 NCBI chr 6:96,008,307...96,057,131
Ensembl chr 6:96,008,455...96,062,951
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:62,777,236...62,787,342
Ensembl chr 5:62,777,352...62,787,369
JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (MGI:2159541|PMID:11850834) MGI PMID:11850834 MGI:2159541 NCBI chr 6:893,377...897,706
Ensembl chr 6:893,381...897,934
JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:43,765,386...44,187,766
Ensembl chr11:43,764,271...44,187,821
JBrowse link
G ILKAP ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chr15:137,740,291...137,765,758
Ensembl chr15:137,740,292...137,765,784
JBrowse link
G NUGGC nuclear GTPase, germinal center associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,775,684...11,826,162
Ensembl chr14:11,775,704...11,826,096
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLFN11 schlafen family member 11 involved_in ISO (PMID:29395061) UniProt PMID:29395061 NCBI chr12:39,974,519...39,996,257
Ensembl chr12:39,974,730...39,996,255
JBrowse link
G TIMELESS timeless circadian regulator involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr 5:21,763,014...21,787,521 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17167
    metabolic process 10632
      regulation of metabolic process 6449
        regulation of macromolecule metabolic process 5664
          regulation of DNA metabolic process 501
            regulation of DNA replication 133
              regulation of DNA-templated DNA replication 46
                negative regulation of DNA-templated DNA replication + 7
                positive regulation of DNA-templated DNA replication + 15
                regulation of DNA endoreduplication + 4
                regulation of DNA replication termination + 0
                regulation of DNA-directed DNA polymerase activity + 13
                regulation of DNA-templated DNA replication initiation + 9
                regulation of mitochondrial DNA replication + 5
                regulation of nuclear cell cycle DNA replication + 13
                regulation of replication fork arrest at rDNA repeats 0
Path 2
Term Annotations click to browse term
  biological_process 17167
    metabolic process 10632
      organic substance metabolic process 10219
        organic cyclic compound metabolic process 3042
          nucleobase-containing compound metabolic process 2568
            nucleic acid metabolic process 2099
              DNA metabolic process 935
                regulation of DNA metabolic process 501
                  regulation of DNA replication 133
                    regulation of DNA-templated DNA replication 46
                      negative regulation of DNA-templated DNA replication + 7
                      positive regulation of DNA-templated DNA replication + 15
                      regulation of DNA endoreduplication + 4
                      regulation of DNA replication termination + 0
                      regulation of DNA-directed DNA polymerase activity + 13
                      regulation of DNA-templated DNA replication initiation + 9
                      regulation of mitochondrial DNA replication + 5
                      regulation of nuclear cell cycle DNA replication + 13
                      regulation of replication fork arrest at rDNA repeats 0
paths to the root