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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated DNA replication
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Accession:GO:0090329 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.
Synonyms:exact_synonym: regulation of DNA-dependent DNA replication



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regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in IMP (PMID:25901030) UniProt PMID:25901030 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in IMP (PMID:17875940) UniProt PMID:17875940 NCBI chr 6:152,970,535...152,983,579
Ensembl chr 6:152,970,519...152,983,579
JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IDA (PMID:19906994) ComplexPortal PMID:19906994 NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258
JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IDA (PMID:11125146), (PMID:19906994) ComplexPortal PMID:11125146 PMID:19906994 NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G LIG3 DNA ligase 3 involved_in IMP (PMID:21878356) CACAO PMID:21878356 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743
JBrowse link
negative regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor involved_in NAS (PMID:10490843) UniProt PMID:10490843 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2F7 E2F transcription factor 7 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:77,021,251...77,065,569
Ensembl chr12:77,021,248...77,065,569
JBrowse link
G E2F8 E2F transcription factor 8 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr16:69,118,010...69,132,588
Ensembl chr16:69,118,010...69,132,588
JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 8:119,833,976...119,855,894
Ensembl chr 8:119,833,976...119,855,894
JBrowse link
G GINS1 GINS complex subunit 1 involved_in IDA (PMID:17170760) ComplexPortal PMID:17170760 NCBI chr20:25,407,673...25,448,563
Ensembl chr20:25,391,008...25,452,700
JBrowse link
G GINS2 GINS complex subunit 2 involved_in IDA (PMID:17170760) ComplexPortal PMID:17170760 NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073
JBrowse link
G GINS3 GINS complex subunit 3 involved_in IDA (PMID:17170760) ComplexPortal PMID:17170760 NCBI chr16:58,392,471...58,406,147
Ensembl chr16:58,295,080...58,406,147
JBrowse link
G GINS4 GINS complex subunit 4 involved_in IDA (PMID:17170760) ComplexPortal PMID:17170760 NCBI chr 8:41,529,261...41,545,030
Ensembl chr 8:41,529,218...41,545,030
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IMP (PMID:11595739) UniProt PMID:11595739 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in IDA (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr17:64,477,785...64,497,054
Ensembl chr17:64,477,785...64,497,054
JBrowse link
G RFC2 replication factor C subunit 2 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 7:74,231,502...74,254,399
Ensembl chr 7:74,231,499...74,254,458
JBrowse link
G RFC3 replication factor C subunit 3 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr13:33,818,149...33,977,377
Ensembl chr13:33,818,069...33,966,558
JBrowse link
G RFC4 replication factor C subunit 4 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 3:186,789,900...186,806,482
Ensembl chr 3:186,789,880...186,807,058
JBrowse link
G RFC5 replication factor C subunit 5 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr12:118,016,703...118,041,448
Ensembl chr12:118,013,588...118,033,130
JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IDA (PMID:11125146) CAFA PMID:11125146 NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258
JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4439421|PMID:20215406) MGI
Ensembl
PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4439421|PMID:20215406)
(MGI:3513706|PMID:15585571)
MGI
Ensembl
PMID:15585571 PMID:20215406 GO_REF:0000107 MGI:3513706 MGI:4439421 NCBI chr 9:128,166,065...128,204,222
Ensembl chr 9:128,161,251...128,204,383
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G involved_in IMP (PMID:29719607) UniProt PMID:29719607 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IDA (PMID:31550240) UniProt PMID:31550240 NCBI chr 7:141,738,321...141,750,488
Ensembl chr 7:141,738,334...141,787,922
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) MGI PMID:2161540 MGI:79015 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
G CDC7 cell division cycle 7 involved_in IMP (PMID:15668232) UniProt PMID:15668232 NCBI chr 1:91,500,851...91,525,764
Ensembl chr 1:91,500,851...91,525,764
JBrowse link
G DBF4 DBF4 zinc finger involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:87,876,493...87,909,553
Ensembl chr 7:87,876,216...87,909,553
JBrowse link
G DBF4B DBF4 zinc finger B involved_in IBA
IMP
(PMID:21873635)
(PMID:15668232)
GO_Central
UniProt
PMID:15668232 PMID:21873635 NCBI chr17:44,708,665...44,752,264
Ensembl chr17:44,708,608...44,752,264
JBrowse link
G INO80 INO80 complex ATPase subunit involved_in IMP (PMID:20237820) UniProt PMID:20237820 NCBI chr15:40,978,880...41,116,280
Ensembl chr15:40,978,880...41,116,280
JBrowse link
G WIZ WIZ zinc finger involved_in IMP (PMID:23545495) UniProt PMID:23545495 NCBI chr19:15,419,978...15,449,956
Ensembl chr19:15,419,978...15,449,956
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SENP2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:3831588|PMID:19090619) MGI PMID:19090619 MGI:3831588 NCBI chr 3:185,586,295...185,633,551
Ensembl chr 3:185,582,496...185,633,551
JBrowse link
regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IDA
IBA
IEA
(PMID:11125146)
(PMID:21873635)
UniProt
GO_Central
InterPro
Ensembl
PMID:11125146 PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258
JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IDA (PMID:24064211) ComplexPortal PMID:24064211 NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in IDA (PMID:26620551) UniProt PMID:26620551 NCBI chr17:49,788,681...49,835,026
Ensembl chr17:49,788,624...49,835,026
JBrowse link
G MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in IDA (PMID:24064211) ComplexPortal PMID:24064211 NCBI chr 5:55,219,564...55,227,315
Ensembl chr 5:55,219,564...55,227,315
JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,410...127,622,436
JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881
JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443
JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in NAS (PMID:30069701) ComplexPortal PMID:30069701 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,728...100,101,940
JBrowse link
G NBN nibrin involved_in TAS (PMID:9590181) UniProt PMID:9590181 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228
JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IBA
IMP
(PMID:21873635)
(PMID:20116089)
GO_Central
UniProt
PMID:20116089 PMID:21873635 NCBI chr15:89,575,469...89,628,023
Ensembl chr15:89,575,469...89,631,056
JBrowse link
G WRNIP1 WRN helicase interacting protein 1 involved_in IDA (PMID:15670210) UniProt PMID:15670210 NCBI chr 6:2,765,393...2,786,952
Ensembl chr 6:2,765,393...2,786,952
JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in IMP (PMID:32183942) UniProt PMID:32183942 NCBI chr18:2,537,530...2,571,505
Ensembl chr18:2,537,525...2,571,509
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3583382|PMID:15980864) MGI
Ensembl
PMID:15980864 GO_REF:0000107 MGI:3583382 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IMP (PMID:19734146) UniProt PMID:19734146 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2159541|PMID:11850834) MGI
Ensembl
PMID:11850834 GO_REF:0000107 MGI:2159541 NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258
JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:71,437,966...71,867,204
Ensembl chr13:71,437,966...71,867,204
JBrowse link
G ILKAP ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chr 2:238,170,402...238,203,695
Ensembl chr 2:238,170,402...238,203,708
JBrowse link
G NUGGC nuclear GTPase, germinal center associated involved_in IMP (PMID:19734146) UniProt PMID:19734146 NCBI chr 8:28,021,964...28,083,936
Ensembl chr 8:28,021,964...28,083,936
JBrowse link
G TIPIN TIMELESS interacting protein involved_in TAS (PMID:17102137) HGNC-UCL PMID:17102137 NCBI chr15:66,336,191...66,386,717
Ensembl chr15:66,336,191...66,386,746
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMSAP3 calmodulin regulated spectrin associated protein family member 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:7,595,863...7,618,304
Ensembl chr19:7,595,863...7,618,304
JBrowse link
G SLFN11 schlafen family member 11 involved_in IDA (PMID:29395061) UniProt PMID:29395061 NCBI chr17:35,350,305...35,373,621
Ensembl chr17:35,350,305...35,373,701
JBrowse link
G TIMELESS timeless circadian regulator involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:56,416,363...56,449,426
Ensembl chr12:56,416,363...56,449,426
JBrowse link
G TIPIN TIMELESS interacting protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:66,336,191...66,386,717
Ensembl chr15:66,336,191...66,386,746
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19600
    metabolic process 12946
      regulation of metabolic process 7795
        regulation of macromolecule metabolic process 6888
          regulation of DNA metabolic process 592
            regulation of DNA replication 148
              regulation of DNA-templated DNA replication 56
                negative regulation of DNA-templated DNA replication + 10
                positive regulation of DNA-templated DNA replication + 14
                regulation of DNA endoreduplication + 4
                regulation of DNA replication termination + 0
                regulation of DNA-directed DNA polymerase activity + 14
                regulation of DNA-templated DNA replication initiation + 15
                regulation of mitochondrial DNA replication + 5
                regulation of nuclear cell cycle DNA replication + 15
                regulation of replication fork arrest at rDNA repeats 0
Path 2
Term Annotations click to browse term
  biological_process 19600
    metabolic process 12946
      organic substance metabolic process 12475
        organic cyclic compound metabolic process 4197
          nucleobase-containing compound metabolic process 3613
            nucleic acid metabolic process 3021
              DNA metabolic process 1125
                regulation of DNA metabolic process 592
                  regulation of DNA replication 148
                    regulation of DNA-templated DNA replication 56
                      negative regulation of DNA-templated DNA replication + 10
                      positive regulation of DNA-templated DNA replication + 14
                      regulation of DNA endoreduplication + 4
                      regulation of DNA replication termination + 0
                      regulation of DNA-directed DNA polymerase activity + 14
                      regulation of DNA-templated DNA replication initiation + 15
                      regulation of mitochondrial DNA replication + 5
                      regulation of nuclear cell cycle DNA replication + 15
                      regulation of replication fork arrest at rDNA repeats 0
paths to the root