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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-dependent DNA replication
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Accession:GO:0090329 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.


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regulation of DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:25901030) RGD PMID:25901030 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
negative regulation of DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5449497|PMID:23064266)
UniProt
RGD
PMID:23064266 GO_REF:0000024 MGI:5449497 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G E2f8 E2F transcription factor 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23064264 PMID:23064266 GO_REF:0000024 GO_REF:0000107 MGI:5449497 MGI:5449498 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
positive regulation of DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1920234 (MGI:4439421|PMID:20215406)
Ensembl
RGD
PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:104772 (MGI:3513706|PMID:15585571), (MGI:4439421|PMID:20215406) RGD PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 3:15,658,479...15,675,716
Ensembl chr 3:15,658,539...15,673,762
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chtf18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:12930902)
UniProt
RGD
PMID:12930902 GO_REF:0000024 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Npm1 nucleophosmin 1 IDA RGD PMID:8123045 RGD:11535022 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) RGD PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
JBrowse link
G Rfc2 replication factor C subunit 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12930902)
UniProt
RGD
PMID:12930902 GO_REF:0000024 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rfc3 replication factor C subunit 3 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
JBrowse link
G Rfc4 replication factor C subunit 4 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
JBrowse link
G Rfc5 replication factor C subunit 5 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ssbp1 single stranded DNA binding protein 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:31550240)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31550240 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Stoml2 stomatin like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:21746876)
UniProt
RGD
PMID:21746876 GO_REF:0000024 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) RGD PMID:2161540 MGI:79015 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5568153|PMID:24651726)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Dbf4 DBF4 zinc finger involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Dbf4b DBF4 zinc finger B involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr10:87,713,805...87,719,197 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911
JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) RGD PMID:23545495 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO MGI:3832730 (MGI:3831588|PMID:19090619) RGD PMID:19090619 MGI:3831588 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
JBrowse link
regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA
(PMID:11125146)
(MGI:2388867|PMID:12192004)
PMID:21873635
RGD PMID:11125146 PMID:12192004 PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO
ISS
IEA
(PMID:26620551)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:26620551 GO_REF:0000024 GO_REF:0000107 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in ISO
IBA
(PMID:20116089)
PMID:21873635
RGD PMID:20116089 PMID:21873635 RGD:13792537 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
JBrowse link
G Wdr18 WD repeat domain 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:9,740,245...9,748,041
Ensembl chr 7:9,739,604...9,748,070
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISO
IEA
ISS
(PMID:15670210)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15670210 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659
JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase like 4 involved_in ISO (PMID:32183942) RGD PMID:32183942 NCBI chr 9:111,440,976...111,523,871
Ensembl chr 9:111,441,027...111,464,749
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3583382|PMID:15980864) RGD PMID:15980864 MGI:3583382 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (MGI:2159541|PMID:11850834) RGD PMID:11850834 MGI:2159541 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (MGI:5619482|PMID:16980615) RGD PMID:16980615 MGI:5619482 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase IDA RGD PMID:9857069 RGD:632254 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892
JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
replication fork protection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1930616 (MGI:2683861|PMID:14681210)
Ensembl
RGD
PMID:14681210 GO_REF:0000107 MGI:2683861 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (MGI:5566975|PMID:24108124) RGD PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4950701|PMID:21191184)
PMID:21873635
UniProt
RGD
PMID:21191184 PMID:21873635 GO_REF:0000024 MGI:4950701, RGD:13792537 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:22704558), (PMID:22705370)
RGD PMID:22704558 PMID:22705370 PMID:21873635 RGD:13792537 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    regulation of biological process 12769
      regulation of metabolic process 6740
        regulation of macromolecule metabolic process 6246
          regulation of macromolecule biosynthetic process 3771
            regulation of cellular macromolecule biosynthetic process 3733
              regulation of DNA replication 115
                regulation of DNA-dependent DNA replication 50
                  negative regulation of DNA-dependent DNA replication + 14
                  positive regulation of DNA-dependent DNA replication + 14
                  regulation of DNA endoreduplication + 4
                  regulation of DNA replication termination + 0
                  regulation of DNA-dependent DNA replication initiation + 7
                  regulation of DNA-directed DNA polymerase activity + 10
                  regulation of mitochondrial DNA replication + 5
                  regulation of nuclear cell cycle DNA replication + 13
                  regulation of replication fork arrest at rDNA repeats 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      biosynthetic process 6071
        organic substance biosynthetic process 5969
          macromolecule biosynthetic process 5030
            cellular macromolecule biosynthetic process 4989
              DNA replication 253
                DNA-dependent DNA replication 151
                  regulation of DNA-dependent DNA replication 50
                    negative regulation of DNA-dependent DNA replication + 14
                    positive regulation of DNA-dependent DNA replication + 14
                    regulation of DNA endoreduplication + 4
                    regulation of DNA replication termination + 0
                    regulation of DNA-dependent DNA replication initiation + 7
                    regulation of DNA-directed DNA polymerase activity + 10
                    regulation of mitochondrial DNA replication + 5
                    regulation of nuclear cell cycle DNA replication + 13
                    regulation of replication fork arrest at rDNA repeats 0
paths to the root