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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of DNA-templated DNA replication
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Accession:GO:0090329 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.
Synonyms:exact_synonym: regulation of DNA-dependent DNA replication


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regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:25901030) RGD PMID:25901030 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) RGD PMID:19906994 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146), (PMID:19906994) RGD PMID:11125146 PMID:19906994 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO
ISS
IEA		 (MGI:5449497|PMID:23064266)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:23064266 GO_REF:0000024 GO_REF:0000107 MGI:5449497 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23064264 PMID:23064266 GO_REF:0000024 GO_REF:0000107 MGI:5449497 MGI:5449498 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chtf18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Gins1 GINS complex subunit 1 involved_in ISO (PMID:17170760) RGD PMID:17170760 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 involved_in ISO (PMID:17170760) RGD PMID:17170760 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 involved_in ISO (PMID:17170760) RGD PMID:17170760 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 involved_in ISO
IEA		 (PMID:17170760)
GO_REF:0000107		 RGD
Ensembl		 PMID:17170760 GO_REF:0000107 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Npm1 nucleophosmin 1 IDA RGD PMID:8123045 RGD:11535022 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) RGD PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Rfc2 replication factor C subunit 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557 		JBrowse link
G Rfc3 replication factor C subunit 3 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rfc4 replication factor C subunit 4 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rfc5 replication factor C subunit 5 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1920234 (MGI:4439421|PMID:20215406)
GO_REF:0000107		 RGD
Ensembl		 PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:104772 (MGI:3513706|PMID:15585571), (MGI:4439421|PMID:20215406) RGD PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 3:15,658,479...15,675,716
Ensembl chr 3:15,658,539...15,673,762 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in ISO (PMID:29719607) RGD PMID:29719607 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO
IEA
ISS		 (PMID:31550240)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31550240 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) RGD PMID:2161540 MGI:79015 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5568153|PMID:24651726)		 UniProt
Ensembl
RGD		 PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Dbf4 DBF4 zinc finger involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbf4b DBF4 zinc finger B involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr10:87,713,805...87,719,197 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) RGD PMID:23545495 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490 		JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO MGI:3832730 (MGI:3831588|PMID:19090619) RGD PMID:19090619 MGI:3831588 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA		 (PMID:11125146)
PMID:21873635
(MGI:2388867|PMID:12192004)		 RGD PMID:11125146 PMID:12192004 PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:24064211) RGD PMID:24064211 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO
ISS		 (PMID:26620551)
GO_REF:0000024		 RGD
UniProt		 PMID:26620551 GO_REF:0000024 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567 		JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in ISO
IEA		 (PMID:24064211)
GO_REF:0000107		 RGD
Ensembl		 PMID:24064211 GO_REF:0000107 NCBI chr 2:44,636,581...44,643,730
Ensembl chr 2:44,636,856...44,642,601 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in ISO
IBA		 (PMID:20116089)
PMID:21873635		 RGD PMID:20116089 PMID:21873635 RGD:13792537 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523 		JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISO
IEA
ISS		 (PMID:15670210)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15670210 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659 		JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine involved_in ISO (PMID:32183942) RGD PMID:32183942 NCBI chr 9:111,440,976...111,523,871
Ensembl chr 9:111,441,027...111,464,749 		JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3583382|PMID:15980864) RGD PMID:15980864 MGI:3583382 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (MGI:2159541|PMID:11850834) RGD PMID:11850834 MGI:2159541 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (MGI:5619482|PMID:16980615) RGD PMID:16980615 MGI:5619482 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase IDA RGD PMID:9857069 RGD:632254 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122 		JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tipin timeless interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      regulation of metabolic process 6861
        regulation of macromolecule metabolic process 6001
          regulation of DNA metabolic process 508
            regulation of DNA replication 134
              regulation of DNA-templated DNA replication 48
                negative regulation of DNA-templated DNA replication + 9
                positive regulation of DNA-templated DNA replication + 14
                regulation of DNA endoreduplication + 4
                regulation of DNA replication termination + 0
                regulation of DNA-directed DNA polymerase activity + 14
                regulation of DNA-templated DNA replication initiation + 8
                regulation of mitochondrial DNA replication + 5
                regulation of nuclear cell cycle DNA replication + 13
                regulation of replication fork arrest at rDNA repeats 0
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      organic substance metabolic process 11623
        organic cyclic compound metabolic process 3374
          nucleobase-containing compound metabolic process 2826
            nucleic acid metabolic process 2315
              DNA metabolic process 1001
                regulation of DNA metabolic process 508
                  regulation of DNA replication 134
                    regulation of DNA-templated DNA replication 48
                      negative regulation of DNA-templated DNA replication + 9
                      positive regulation of DNA-templated DNA replication + 14
                      regulation of DNA endoreduplication + 4
                      regulation of DNA replication termination + 0
                      regulation of DNA-directed DNA polymerase activity + 14
                      regulation of DNA-templated DNA replication initiation + 8
                      regulation of mitochondrial DNA replication + 5
                      regulation of nuclear cell cycle DNA replication + 13
                      regulation of replication fork arrest at rDNA repeats 0
paths to the root