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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of oxidative phosphorylation
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Accession:GO:0090324 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.


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negative regulation of oxidative phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1599177
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:1624291
G Pde12 phosphodiesterase 12 JBrowse link 16 2,357,028 2,367,069 RGD:1600115
RGD:1624291
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1624291
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:1624291
RGD:1600115
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:14995471
negative regulation of mitochondrial electron transport, NADH to ubiquinone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 15 59,990,131 60,056,710 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19676
    negative regulation of biological process 5608
      negative regulation of metabolic process 3221
        negative regulation of ATP metabolic process 31
          negative regulation of oxidative phosphorylation 9
            negative regulation of mitochondrial ATP synthesis coupled electron transport + 1
            negative regulation of mitochondrial ATP synthesis coupled proton transport 0
Path 2
Term Annotations click to browse term
  biological_process 19676
    biological regulation 13597
      regulation of biological process 12921
        regulation of metabolic process 6872
          regulation of cellular metabolic process 6113
            regulation of phosphorus metabolic process 1868
              regulation of phosphate metabolic process 1867
                regulation of phosphorylation 1665
                  regulation of oxidative phosphorylation 37
                    negative regulation of oxidative phosphorylation 9
                      negative regulation of mitochondrial ATP synthesis coupled electron transport + 1
                      negative regulation of mitochondrial ATP synthesis coupled proton transport 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.