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ONTOLOGY REPORT - ANNOTATIONS
Term:nucleic acid phosphodiester bond hydrolysis
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Accession:GO:0090305 term browser browse the term
Definition:The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
Synonyms:exact_synonym: nucleic acid cleavage

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nucleic acid phosphodiester bond hydrolysis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase JBrowse link 12 48,257,575 48,262,244 RGD:1600115
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase JBrowse link 3 82,874,242 82,907,467 RGD:1600115
G Ankle1 ankyrin repeat and LEM domain containing 1 JBrowse link 16 19,799,943 19,826,057 RGD:1600115
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 JBrowse link X 23,146,085 23,166,676 RGD:1600115
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1600115
G Aptx aprataxin JBrowse link 5 56,987,714 57,009,481 RGD:1600115
G Aste1 asteroid homolog 1 JBrowse link 8 113,936,991 113,954,833 RGD:1600115
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Dclre1a DNA cross-link repair 1A JBrowse link 1 277,335,792 277,355,701 RGD:1600115
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1600115
G Dclre1c DNA cross-link repair 1C JBrowse link 17 78,782,512 78,812,140 RGD:1600115
G Ddx1 DEAD-box helicase 1 JBrowse link 6 38,422,892 38,453,762 RGD:1624291
G Dna2 DNA replication helicase/nuclease 2 RGD:1600115
G Dnase1l1 deoxyribonuclease 1-like 1 JBrowse link X 156,429,521 156,438,066 RGD:1600115
G Dxo decapping exoribonuclease JBrowse link 20 4,517,307 4,519,391 RGD:1624291
RGD:13792537
RGD:1600115
G Eme1 essential meiotic structure-specific endonuclease 1 JBrowse link 10 82,366,820 82,375,510 RGD:1600115
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link 10 14,253,552 14,257,017 RGD:1600115
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1624291
RGD:1600115
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:1600115
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1600115
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1600115
G Exd1 exonuclease 3'-5' domain containing 1 JBrowse link 3 111,326,388 111,354,419 RGD:1600115
G Exd2 exonuclease 3'-5' domain containing 2 JBrowse link 6 104,017,620 104,051,442 RGD:1624291
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1600115
G Exo5 exonuclease 5 JBrowse link 5 139,849,930 139,853,247 RGD:1600115
G Fancm FA complementation group M JBrowse link 6 86,823,195 86,877,067 RGD:1600115
G Fen1 flap structure-specific endonuclease 1 JBrowse link 1 226,251,516 226,256,160 RGD:1624291
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1600115
G Harbi1 harbinger transposase derived 1 JBrowse link 3 80,614,886 80,624,213 RGD:1600115
G Las1l LAS1-like, ribosome biogenesis factor JBrowse link X 65,081,591 65,102,344 RGD:1600115
G Meiob meiosis specific with OB-fold JBrowse link 10 14,174,645 14,206,026 RGD:1600115
G Mgme1 mitochondrial genome maintenance exonuclease 1 JBrowse link 3 138,397,925 138,406,672 RGD:1600115
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1600115
G N4bp2 NEDD4 binding protein 2 JBrowse link 14 43,963,353 44,092,844 RGD:1600115
G Neil1 nei-like DNA glycosylase 1 JBrowse link 8 61,817,258 61,824,023 RGD:1600115
G Pde12 phosphodiesterase 12 JBrowse link 16 2,357,028 2,367,069 RGD:1624291
G Pelo pelota mRNA surveillance and ribosome rescue factor JBrowse link 2 47,266,758 47,268,526 RGD:1600115
G Pgap1 post-GPI attachment to proteins inositol deacylase 1 JBrowse link 9 61,066,170 61,134,963 RGD:1600115
G Pld3 phospholipase D family, member 3 JBrowse link 1 84,339,269 84,361,686 RGD:1600115
G Pld4 phospholipase D family, member 4 JBrowse link 6 137,323,713 137,331,231 RGD:1600115
G Pold1 DNA polymerase delta 1, catalytic subunit JBrowse link 1 100,538,066 100,554,105 RGD:1600115
G Pole DNA polymerase epsilon, catalytic subunit JBrowse link 12 52,403,533 52,452,075 RGD:1600115
G Polg DNA polymerase gamma, catalytic subunit JBrowse link 1 141,172,117 141,188,893 RGD:1600115
G Rad1 RAD1 checkpoint DNA exonuclease JBrowse link 2 60,461,513 60,469,646 RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:13792537
G Rad9a RAD9 checkpoint clamp component A JBrowse link 1 219,443,347 219,450,574 RGD:1600115
G Rad9b RAD9 checkpoint clamp component B JBrowse link 12 39,699,076 39,731,218 RGD:1600115
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1600115
G Rbbp8 RB binding protein 8, endonuclease JBrowse link 18 3,134,630 3,227,702 RGD:1600115
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit JBrowse link 20 44,803,664 44,961,362 RGD:1600115
G Rexo1 RNA exonuclease 1 homolog JBrowse link 7 12,022,268 12,041,660 RGD:1600115
G Rexo1l1-ps1 REX1, RNA exonuclease 1 homolog-like 1, pseudogene 1 JBrowse link 2 143,830,019 143,832,825 RGD:1600115
G Rexo5 RNA exonuclease 5 JBrowse link 1 189,549,960 189,643,698 RGD:1600115
G Rnase1 ribonuclease A family member 1, pancreatic RGD:1600115
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 (pancreatic) JBrowse link 15 28,043,491 28,045,098 RGD:1600115
G Setmar SET domain and mariner transposase fusion gene JBrowse link 4 140,092,346 140,104,495 RGD:1624291
G Slc25a16 solute carrier family 25 member 16 JBrowse link 20 27,283,383 27,308,069 RGD:1600115
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1600115
G Stk31 serine threonine kinase 31 JBrowse link 4 79,055,493 79,153,849 RGD:1600115
G Tatdn1 TatD DNase domain containing 1 JBrowse link 7 98,782,164 98,813,001 RGD:1600115
G Tdp1 tyrosyl-DNA phosphodiesterase 1 JBrowse link 6 123,895,860 123,963,688 RGD:1600115
G Tdp2 tyrosyl-DNA phosphodiesterase 2 JBrowse link 17 42,229,667 42,241,025 RGD:1600115
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1600115
G Trex2 three prime repair exonuclease 2 JBrowse link X 157,374,305 157,375,913 RGD:1600115
G Tsen15 tRNA splicing endonuclease subunit 15 JBrowse link 13 69,765,093 69,781,019 RGD:1600115
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1600115
G Zranb3 zinc finger RANBP2-type containing 3 JBrowse link 13 44,661,375 44,812,430 RGD:1600115
apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1600115
G Dffb DNA fragmentation factor subunit beta JBrowse link 5 171,250,559 171,261,875 RGD:628524
RGD:1600115
RGD:13792537
RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:728743
RGD:13792537
RGD:1624291
G Dnase2 deoxyribonuclease 2, lysosomal JBrowse link 19 26,022,855 26,025,523 RGD:13792537
G Dnase2b deoxyribonuclease 2 beta JBrowse link 2 252,436,363 252,475,506 RGD:13792537
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:1624291
RGD:13792537
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:13792537
G Foxl2 forkhead box L2 JBrowse link 8 107,194,492 107,197,644 RGD:1624291
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bop1 BOP1 ribosomal biogenesis factor JBrowse link 7 117,514,529 117,538,342 RGD:1624291
G Nol9 nucleolar protein 9 JBrowse link 5 169,213,076 169,233,173 RGD:13792537
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:11535027
cleavage involved in rRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC103690013 H/ACA ribonucleoprotein complex subunit 2 JBrowse link 10 37,069,387 37,072,758 RGD:13792537
G Nhp2 NHP2 ribonucleoprotein JBrowse link 10 34,975,701 34,979,082 RGD:13792537
G Nob1 NIN1 (RPN12) binding protein 1 homolog JBrowse link 19 38,397,466 38,409,924 RGD:1600115
G Rrp36 ribosomal RNA processing 36 JBrowse link 9 16,618,853 16,627,128 RGD:1600115
deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dcp1a decapping mRNA 1A JBrowse link 16 6,542,415 6,583,856 RGD:13792537
G Dcp1b decapping mRNA 1B JBrowse link 4 151,249,654 151,287,018 RGD:13792537
G Edc3 enhancer of mRNA decapping 3 JBrowse link 8 62,482,126 62,527,665 RGD:13792537
G Edc4 enhancer of mRNA decapping 4 JBrowse link 19 37,852,659 37,864,651 RGD:13792537
DNA catabolic process, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:1624291
RGD:13792537
RGD:13464261
G Dnase1l1 deoxyribonuclease 1-like 1 JBrowse link X 156,429,521 156,438,066 RGD:13792537
G Dnase1l2 deoxyribonuclease 1 like 2 JBrowse link 10 13,812,335 13,814,514 RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:1624291
RGD:13792537
RGD:13464261
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:13792537
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:1624291
G Rexo4 REX4 homolog, 3'-5' exonuclease JBrowse link 3 5,500,578 5,510,908 RGD:1624291
RGD:13792537
G Setmar SET domain and mariner transposase fusion gene JBrowse link 4 140,092,346 140,104,495 RGD:1624291
G Spo11 SPO11, initiator of meiotic double stranded breaks JBrowse link 3 170,991,573 171,008,226 RGD:1600115
DNA catabolic process, exonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aen apoptosis enhancing nuclease JBrowse link 1 140,584,328 140,593,749 RGD:13792537
G Eri1 exoribonuclease 1 JBrowse link 16 60,307,148 60,327,237 RGD:13792537
G Eri3 ERI1 exoribonuclease family member 3 JBrowse link 5 136,406,009 136,533,408 RGD:13792537
G Isg20 interferon stimulated exonuclease gene 20 JBrowse link 1 140,602,553 140,608,892 RGD:1624291
RGD:13792537
G Rexo4 REX4 homolog, 3'-5' exonuclease JBrowse link 3 5,500,578 5,510,908 RGD:1624291
RGD:13792537
G Xrn2 5'-3' exoribonuclease 2 JBrowse link 3 141,224,858 141,298,272 RGD:1624291
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
G Fcf1 FCF1 rRNA-processing protein JBrowse link 6 108,796,182 108,808,051 RGD:1624291
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:1624291
G Tbl3 transducin (beta)-like 3 JBrowse link 10 14,066,984 14,072,197 RGD:13792537
G Utp23 UTP23, small subunit processome component JBrowse link 7 91,384,329 91,389,605 RGD:1624291
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
G AC135409.1 RGD:13792537
G Fcf1 FCF1 rRNA-processing protein JBrowse link 6 108,796,182 108,808,051 RGD:1624291
G Kri1 KRI1 homolog JBrowse link 8 22,301,025 22,317,049 RGD:13792537
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:1624291
G Rpp40 ribonuclease P/MRP subunit p40 JBrowse link 17 29,638,647 29,647,709 RGD:13792537
G Rps21 ribosomal protein S21 JBrowse link 3 175,629,176 175,630,198 RGD:13792537
G Rrs1 ribosome biogenesis regulator 1 homolog JBrowse link 5 9,430,710 9,432,343 RGD:13792537
endonucleolytic cleavage involved in tRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpp40 ribonuclease P/MRP subunit p40 JBrowse link 17 29,638,647 29,647,709 RGD:13792537
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bms1 BMS1 ribosome biogenesis factor JBrowse link 4 150,433,567 150,471,783 RGD:13792537
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:13792537
G Tsr1 TSR1, ribosome maturation factor JBrowse link 10 61,746,070 61,757,518 RGD:13792537
endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC135409.1 RGD:13792537
G Rps21 ribosomal protein S21 JBrowse link 3 175,629,176 175,630,198 RGD:13792537
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:13792537
G Tbl3 transducin (beta)-like 3 JBrowse link 10 14,066,984 14,072,197 RGD:13792537
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eri1 exoribonuclease 1 JBrowse link 16 60,307,148 60,327,237 RGD:13792537
G Eri3 ERI1 exoribonuclease family member 3 JBrowse link 5 136,406,009 136,533,408 RGD:13792537
G Exosc10 exosome component 10 JBrowse link 5 165,374,964 165,398,195 RGD:13792537
G Exosc2 exosome component 2 JBrowse link 3 10,151,734 10,161,997 RGD:13792537
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:13792537
G Exosc7 exosome component 7 JBrowse link 8 132,204,628 132,229,968 RGD:13792537
G Exosc8 exosome component 8 JBrowse link 2 143,925,643 143,932,240 RGD:13792537
G Exosc9 exosome component 9 JBrowse link 2 123,264,679 123,275,623 RGD:13792537
meiotic DNA double-strand break formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC119332.1 RGD:1600115
G Hormad1 HORMA domain containing 1 JBrowse link 2 197,681,820 197,720,197 RGD:1600115
RGD:1624291
G Iho1 interactor of HORMAD1 1 JBrowse link 8 117,182,484 117,215,390 RGD:1624291
G Mei4 meiotic double-stranded break formation protein 4 JBrowse link 8 89,369,417 89,556,942 RGD:1624291
RGD:13792537
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:13792537
G RGD1563323 similar to hypothetical protein FLJ22531 JBrowse link 1 219,864,108 219,952,143 RGD:1624291
G Spo11 SPO11, initiator of meiotic double stranded breaks JBrowse link 3 170,991,573 171,008,226 RGD:13792537
meiotic DNA double-strand break formation involved in reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd31 ankyrin repeat domain 31 JBrowse link 2 27,571,129 27,743,668 RGD:1624291
mitochondrial tRNA 3'-trailer cleavage, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elac2 elaC ribonuclease Z 2 JBrowse link 10 51,478,378 51,501,167 RGD:1600115
RGD:13792537
RGD:1624291
mRNA cleavage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
G LOC103690054 DNA-directed RNA polymerase II subunit RPB9 JBrowse link 1 91,041,173 91,042,258 RGD:1600115
G Polr1h RNA polymerase I subunit H JBrowse link 20 2,088,518 2,092,436 RGD:1600115
G Polr2i RNA polymerase II subunit I JBrowse link 1 88,686,812 88,688,249 RGD:1600115
mRNA cleavage involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1624291
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1624291
RGD:1600115
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291
G Ago4 argonaute RISC component 4 JBrowse link 5 144,501,875 144,557,165 RGD:1624291
G Mir196a microRNA 196a JBrowse link 7 144,584,235 144,584,344 RGD:1624291
G Mir196b microRNA 196b JBrowse link 4 82,199,056 82,199,140 RGD:1624291
G Mir196c microRNA 196c JBrowse link 10 84,113,578 84,113,657 RGD:1624291
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:1624291
mRNA cleavage involved in gene silencing by siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1624291
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
RGD:1624291
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291
G Ago4 argonaute RISC component 4 JBrowse link 5 144,501,875 144,557,165 RGD:1624291
mRNA cleavage involved in mRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1624291
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 JBrowse link 5 166,409,460 166,430,291 RGD:13781945
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:13462066
nucleotide-excision repair, DNA incision term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:1624291
RGD:13792537
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit JBrowse link 18 25,037,668 25,068,380 RGD:1624291
RGD:13792537
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Fan1 FANCD2 and FANCI associated nuclease 1 JBrowse link 1 125,182,117 125,209,772 RGD:1624291
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:1624291
G Xpa XPA, DNA damage recognition and repair factor JBrowse link 5 61,749,767 61,793,641 RGD:1624291
RGD:13792537
nucleotide-excision repair, DNA incision, 3'-to lesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bivm basic, immunoglobulin-like variable motif containing JBrowse link 9 50,884,888 50,921,133 RGD:13792537
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Ercc5 ERCC excision repair 5, endonuclease JBrowse link 9 50,928,847 50,970,962 RGD:1624291
RGD:13792537
nucleotide-excision repair, DNA incision, 5'-to lesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC117889.1 RGD:13792537
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
RGD:13792537
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Nthl1 nth-like DNA glycosylase 1 JBrowse link 10 13,996,660 14,002,827 RGD:1624291
RGD:13792537
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:9685355
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10403035
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:10402776
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
positive regulation of meiotic DNA double-strand break formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd31 ankyrin repeat domain 31 JBrowse link 2 27,571,129 27,743,668 RGD:1624291
positive regulation of mRNA cleavage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nudt21 nudix hydrolase 21 JBrowse link 19 11,451,366 11,470,637 RGD:1600115
RGD:1624291
pre-mRNA cleavage required for polyadenylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC096468.1 RGD:13792537
G Cpsf2 cleavage and polyadenylation specific factor 2 JBrowse link 6 125,870,372 125,898,039 RGD:13792537
G Cpsf4 cleavage and polyadenylation specific factor 4 JBrowse link 12 11,199,893 11,215,690 RGD:13792537
G Cpsf6 cleavage and polyadenylation specific factor 6 JBrowse link 7 60,385,688 60,417,661 RGD:1624291
G Cpsf7 cleavage and polyadenylation specific factor 7 JBrowse link 1 226,572,399 226,596,185 RGD:1600115
RGD:1624291
G Cstf2 cleavage stimulation factor subunit 2 JBrowse link X 104,882,726 104,909,746 RGD:13792537
G Cstf2t cleavage stimulation factor subunit 2, tau variant JBrowse link 1 249,574,954 249,578,520 RGD:13792537
G Fip1l1 factor interacting with PAPOLA and CPSF1 JBrowse link 14 36,150,381 36,208,395 RGD:13792537
RGD:1600115
G Ncbp1 nuclear cap binding protein subunit 1 JBrowse link 5 61,734,118 61,767,098 RGD:1624291
RGD:1600115
G Ncbp2 nuclear cap binding protein subunit 2 JBrowse link 11 72,071,838 72,103,087 RGD:1624291
G Nudt21 nudix hydrolase 21 JBrowse link 19 11,451,366 11,470,637 RGD:1624291
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific JBrowse link 1 225,151,462 225,162,445 RGD:1624291
RGD:1600115
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:1624291
RNA phosphodiester bond hydrolysis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ang2 angiogenin, ribonuclease A family, member 2 JBrowse link 15 28,103,688 28,121,494 RGD:1600115
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:13792537
G Ear1 eosinophil-associated, ribonuclease A family, member 1 JBrowse link 15 28,260,133 28,261,049 RGD:1600115
G Helz2 helicase with zinc finger 2 JBrowse link 3 176,730,024 176,744,382 RGD:1600115
G LOC100361866 eosinophil cationic protein-like JBrowse link 15 28,240,548 28,241,466 RGD:1600115
G Rnase1 ribonuclease A family member 1, pancreatic RGD:1624291
G Rnase10 ribonuclease A family member 10 JBrowse link 15 27,930,581 27,933,873 RGD:1600115
G Rnase11 ribonuclease A family member 11 JBrowse link 15 27,972,201 27,977,885 RGD:1600115
G Rnase12 ribonuclease A family member 12 JBrowse link 15 27,981,044 27,993,044 RGD:1600115
G Rnase13 ribonuclease A family member 13 JBrowse link 15 28,322,851 28,325,875 RGD:1600115
G Rnase17 ribonuclease 17 JBrowse link 15 28,204,043 28,204,929 RGD:1600115
G Rnase2 ribonuclease A family member 2 JBrowse link 15 28,154,482 28,155,291 RGD:1624291
G Rnase3 ribonuclease A family member 3 JBrowse link 15 28,216,744 28,217,614 RGD:1600115
G Rnase4 ribonuclease A family member 4 JBrowse link 15 28,018,040 28,035,395 RGD:1624291
G Rnase6 ribonuclease A family member k6 JBrowse link 15 28,080,307 28,084,269 RGD:1624291
G Rnase9 ribonuclease A family member 9 JBrowse link 15 27,964,000 27,968,492 RGD:1600115
G Rnasel ribonuclease L JBrowse link 13 71,188,712 71,202,636 RGD:1600115
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 JBrowse link 3 153,210,829 153,250,705 RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
RNA phosphodiester bond hydrolysis, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC118772.1 RGD:1600115
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1600115
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1600115
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1600115
G Cpsf3 cleavage and polyadenylation specific factor 3 JBrowse link 6 43,363,792 43,391,712 RGD:1600115
G Dbr1 debranching RNA lariats 1 JBrowse link 8 107,826,690 107,838,186 RGD:1600115
G Dgcr8 DGCR8 microprocessor complex subunit JBrowse link 11 86,852,682 86,885,233 RGD:1600115
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1600115
G Edc3 enhancer of mRNA decapping 3 JBrowse link 8 62,482,126 62,527,665 RGD:1600115
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:1600115
G Endou endonuclease, poly(U)-specific JBrowse link 7 139,202,342 139,223,022 RGD:1600115
G Endov endonuclease V JBrowse link 10 108,630,723 108,646,679 RGD:1600115
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1600115
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1600115
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:1600115
G Fen1 flap structure-specific endonuclease 1 JBrowse link 1 226,251,516 226,256,160 RGD:1600115
G Lactb2 lactamase, beta 2 JBrowse link 5 4,982,348 5,005,111 RGD:1624291
RGD:1600115
G LOC103690354 ribonuclease pancreatic beta-type JBrowse link 15 28,073,963 28,075,677 RGD:1600115
G LOC103694852 ribonuclease K6-like RGD:1600115
G LOC103694853 ribonuclease pancreatic gamma-type RGD:1600115
G LOC688828 similar to Nucleoside diphosphate-linked moiety X motif 16 (Nudix motif 16) JBrowse link 8 113,687,983 113,689,657 RGD:1600115
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 9 85,542,763 85,547,814 RGD:1600115
G Nob1 NIN1 (RPN12) binding protein 1 homolog JBrowse link 19 38,397,466 38,409,924 RGD:1600115
G Nudt16 nudix hydrolase 16 JBrowse link 8 113,673,069 113,675,124 RGD:1624291
G Nudt16l1 nudix hydrolase 16 like 1 JBrowse link 10 10,829,866 10,831,782 RGD:1600115
G Piwil1 piwi-like RNA-mediated gene silencing 1 JBrowse link 12 31,608,641 31,629,961 RGD:1600115
G Piwil2 piwi-like RNA-mediated gene silencing 2 JBrowse link 15 52,037,693 52,116,277 RGD:1600115
G Piwil4 piwi-like RNA-mediated gene silencing 4 JBrowse link 8 13,208,774 13,251,970 RGD:1600115
G Pop1 POP1 homolog, ribonuclease P/MRP subunit JBrowse link 7 73,270,403 73,298,209 RGD:13792537
G Pop4 POP4 homolog, ribonuclease P/MRP subunit JBrowse link 1 94,661,127 94,669,461 RGD:1600115
G Pop5 POP5 homolog, ribonuclease P/MRP subunit JBrowse link 12 47,138,346 47,143,152 RGD:1600115
G Pop7 POP7 homolog, ribonuclease P/MRP subunit JBrowse link 12 22,259,713 22,260,754 RGD:13792537
G Prorp protein only RNase P catalytic subunit JBrowse link 6 76,079,880 76,171,298 RGD:1600115
G Rida reactive intermediate imine deaminase A homolog JBrowse link 7 73,256,506 73,270,308 RGD:1600115
G Rnase1 ribonuclease A family member 1, pancreatic RGD:1600115
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 (pancreatic) JBrowse link 15 28,043,491 28,045,098 RGD:1600115
G Rnase1l2 ribonuclease, RNase A family, 1-like 2 (pancreatic) JBrowse link 15 28,127,147 28,128,797 RGD:1600115
G Rnase6 ribonuclease A family member k6 JBrowse link 15 28,080,307 28,084,269 RGD:1600115
G Rnaseh1 ribonuclease H1 JBrowse link 6 47,916,188 47,925,582 RGD:13792537
G Rnaseh2a ribonuclease H2, subunit A JBrowse link 19 26,074,980 26,084,780 RGD:1600115
G Rnaseh2b ribonuclease H2, subunit B JBrowse link 15 45,422,010 45,472,792 RGD:1600115
G Rnasek ribonuclease K JBrowse link 10 56,848,367 56,850,085 RGD:1600115
G Rnaset2 ribonuclease T2 JBrowse link 1 53,174,879 53,192,048 RGD:1600115
G Rpp14 ribonuclease P/MRP subunit p14 JBrowse link 15 18,625,963 18,636,157 RGD:1600115
G Rpp21 ribonuclease P/MRP subunit p21 JBrowse link 20 2,515,541 2,517,471 RGD:1600115
G Rpp25 ribonuclease P and MRP subunit p25 JBrowse link 8 62,283,336 62,284,716 RGD:1600115
G Rpp30 ribonuclease P/MRP subunit p30 JBrowse link 1 254,697,247 254,720,093 RGD:13792537
G Rpp38 ribonuclease P/MRP subunit p38 JBrowse link 17 78,915,450 78,919,144 RGD:1600115
G Slfn13 schlafen family member 13 JBrowse link 10 70,326,157 70,343,024 RGD:1600115
G Slfn14 schlafen family member 14 JBrowse link 10 70,493,340 70,504,810 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10		 61,526,024
61,771,912		 61,542,583
62,007,030		 RGD:1600115
G Snd1 staphylococcal nuclease and tudor domain containing 1 JBrowse link 4 55,772,377 56,171,669 RGD:1600115
G Tsen2 tRNA splicing endonuclease subunit 2 JBrowse link 4 147,455,506 147,490,869 RGD:1600115
G Tsen34 tRNA splicing endonuclease subunit 34 JBrowse link 1 64,023,924 64,031,756 RGD:1600115
G Tsen34l1 tRNA splicing endonuclease subunit 34-like 1 JBrowse link 1 64,092,224 64,100,061 RGD:1600115
G Tsn translin JBrowse link 13 34,240,809 34,251,671 RGD:1600115
G Tsnax translin-associated factor X JBrowse link 19 57,771,539 57,785,567 RGD:1600115
G Ybey ybeY metalloendoribonuclease JBrowse link 20 12,917,111 12,926,587 RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
RNA phosphodiester bond hydrolysis, exonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angel1 angel homolog 1 JBrowse link 6 110,644,327 110,681,397 RGD:1600115
G Angel2 angel homolog 2 JBrowse link 13 109,505,021 109,520,976 RGD:1600115
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:1600115
G Cnot2 CCR4-NOT transcription complex, subunit 2 JBrowse link 7 59,526,105 59,617,307 RGD:1600115
G Cnot6 CCR4-NOT transcription complex, subunit 6 JBrowse link 10 35,144,291 35,195,126 RGD:1600115
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 14 15,059,101 15,148,255 RGD:1600115
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1600115
G Cnot8 CCR4-NOT transcription complex, subunit 8 JBrowse link 10 43,538,150 43,551,271 RGD:1600115
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1600115
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease JBrowse link 15 83,466,330 83,494,107 RGD:1600115
G Dis3l DIS3-like exosome 3'-5' exoribonuclease JBrowse link 8 69,771,211 69,807,880 RGD:1600115
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 JBrowse link 9 93,767,837 94,161,106 RGD:1600115
G Eri2 ERI1 exoribonuclease family member 2 JBrowse link 1 189,540,145 189,549,891 RGD:1600115
G Exd2 exonuclease 3'-5' domain containing 2 JBrowse link 6 104,017,620 104,051,442 RGD:1600115
G Exosc1 exosome component 1 JBrowse link 1 261,169,798 261,179,865 RGD:1600115
G Exosc4 exosome component 4 JBrowse link 7 117,390,302 117,393,044 RGD:1600115
G Exosc5 exosome component 5 JBrowse link 1 82,452,104 82,461,607 RGD:1600115
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1600115
G Isg20 interferon stimulated exonuclease gene 20 JBrowse link 1 140,602,553 140,608,892 RGD:1600115
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 JBrowse link 2 187,302,192 187,311,677 RGD:1600115
G LOC100912393 mRNA-decapping enzyme 2-like JBrowse link 9 3,940,948 3,965,964 RGD:1600115
G Noct nocturnin JBrowse link 2 140,286,661 140,306,869 RGD:1600115
G Pan2 poly(A) specific ribonuclease subunit PAN2 JBrowse link 7 2,717,021 2,736,541 RGD:1600115
G Pan3 poly(A) specific ribonuclease subunit PAN3 JBrowse link 12 9,214,116 9,331,901 RGD:1600115
G Parn poly(A)-specific ribonuclease JBrowse link 10 1,309,724 1,461,123 RGD:1624291
G Pde12 phosphodiesterase 12 JBrowse link 16 2,357,028 2,367,069 RGD:1600115
RGD:1624291
G Pnldc1 PARN like, ribonuclease domain containing 1 JBrowse link 1 48,038,830 48,058,400 RGD:1600115
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 14 113,530,470 113,561,645 RGD:1600115
G Rexo2 RNA exonuclease 2 JBrowse link 8 52,802,604 52,814,321 RGD:1600115
G Toe1 target of EGR1, exonuclease JBrowse link 5 135,659,733 135,663,299 RGD:1624291
G Trir telomerase RNA component interacting RNase JBrowse link 19 26,142,720 26,146,136 RGD:1624291
RGD:13792537
G Usb1 U6 snRNA biogenesis phosphodiesterase 1 JBrowse link 19 10,105,750 10,118,701 RGD:1600115
G Xrn1 5'-3' exoribonuclease 1 JBrowse link 8 103,774,125 103,883,563 RGD:1624291
G Xrn2 5'-3' exoribonuclease 2 JBrowse link 3 141,224,858 141,298,272 RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
tRNA 3'-trailer cleavage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polr3k RNA polymerase III subunit K JBrowse link 3 177,374,812 177,379,009 RGD:1600115
tRNA 3'-trailer cleavage, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elac1 elaC ribonuclease Z 1 JBrowse link 18 69,706,522 69,723,869 RGD:13792537
UV-damage excision repair, DNA incision term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xpc XPC complex subunit, DNA damage recognition and repair factor JBrowse link 4 123,134,457 123,161,985 RGD:1624291
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      organic substance metabolic process 11297
        macromolecule metabolic process 9765
          nucleic acid metabolic process 4782
            nucleic acid phosphodiester bond hydrolysis 265
              DNA catabolic process, endonucleolytic + 27
              DNA catabolic process, exonucleolytic 6
              RNA phosphodiester bond hydrolysis + 159
              UV-damage excision repair, DNA incision 1
              deadenylation-independent decapping of nuclear-transcribed mRNA + 5
              gene conversion at mating-type locus, DNA double-strand break formation 0
              meiotic DNA double-strand break formation + 8
              nucleotide-excision repair, DNA incision + 11
              viral DNA cleavage involved in viral genome maturation 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5276
            nucleic acid metabolic process 4782
              nucleic acid phosphodiester bond hydrolysis 265
                DNA catabolic process, endonucleolytic + 27
                DNA catabolic process, exonucleolytic 6
                RNA phosphodiester bond hydrolysis + 159
                UV-damage excision repair, DNA incision 1
                deadenylation-independent decapping of nuclear-transcribed mRNA + 5
                gene conversion at mating-type locus, DNA double-strand break formation 0
                meiotic DNA double-strand break formation + 8
                nucleotide-excision repair, DNA incision + 11
                viral DNA cleavage involved in viral genome maturation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.