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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleic acid phosphodiester bond hydrolysis
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Accession:GO:0090305 term browser browse the term
Definition:The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
Synonyms:exact_synonym: nucleic acid cleavage


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nucleic acid phosphodiester bond hydrolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (PMID:18710941) RGD PMID:18710941 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Dxo decapping exoribonuclease involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:5488528|PMID:23523372)
GO_REF:0000024		 RGD
UniProt		 PMID:23523372 PMID:21873635 GO_REF:0000024 MGI:5488528, RGD:13792537 NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:22285541) RGD PMID:22285541 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 involved_in ISO (PMID:18499658) RGD PMID:18499658 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Pde12 phosphodiesterase 12 involved_in ISO (PMID:22285541) RGD PMID:22285541 NCBI chr16:1,915,386...1,925,427
Ensembl chr16:1,915,386...1,925,887 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:22231448) RGD PMID:22231448 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcp1a decapping mRNA 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:5,656,788...5,702,151
Ensembl chr16:5,656,773...5,702,140 		JBrowse link
G Dcp1b decapping mRNA 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145 		JBrowse link
G Edc3 enhancer of mRNA decapping 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:58,106,129...58,151,685
Ensembl chr 8:58,106,175...58,151,671 		JBrowse link
G Edc4 enhancer of mRNA decapping 4 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000002		 InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758 		JBrowse link
meiotic DNA double-strand break formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC119332.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:201,899,310...201,989,570 JBrowse link
G C1h11orf80 similar to human chromosome 11 open reading frame 80 involved_in ISO (MGI:5752405|PMID:26917764) RGD PMID:26917764 MGI:5752405 NCBI chr 1:201,902,564...201,989,945 JBrowse link
G Hormad1 HORMA domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4868505|PMID:21079677), (MGI:5009722|PMID:21478856)		 UniProt
RGD		 PMID:21079677 PMID:21478856 GO_REF:0000024 MGI:4868505 MGI:5009722 NCBI chr 2:183,115,815...183,152,383
Ensembl chr 2:183,116,716...183,152,383 		JBrowse link
G Iho1 interactor of HORMAD1 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5822944|PMID:27723721)		 RGD PMID:27723721 PMID:21873635 MGI:5822944, RGD:13792537 NCBI chr 8:109,091,134...109,126,386
Ensembl chr 8:109,092,758...109,125,434 		JBrowse link
G Mei4 meiotic double-stranded break formation protein 4 involved_in IBA
ISO		 PMID:21873635
(MGI:4457793|PMID:20551173)		 RGD PMID:20551173 PMID:21873635 MGI:4457793, RGD:13792537 NCBI chr 8:82,765,661...82,939,649
Ensembl chr 8:82,765,661...82,939,649 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Spo11 SPO11, initiator of meiotic double stranded breaks involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925 		JBrowse link
meiotic DNA double-strand break formation involved in reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd31 ankyrin repeat domain 31 involved_in ISO (MGI:6316415|PMID:31003867), (MGI:6316551|PMID:31000436) RGD PMID:31000436 PMID:31003867 MGI:6316415 MGI:6316551 NCBI chr 2:28,079,187...28,241,722
Ensembl chr 2:28,092,882...28,241,719 		JBrowse link
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp36 zinc finger protein 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16364915)		 UniProt
RGD		 PMID:16364915 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
positive regulation of meiotic DNA double-strand break formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd31 ankyrin repeat domain 31 involved_in ISO (MGI:6316415|PMID:31003867), (MGI:6316551|PMID:31000436) RGD PMID:31000436 PMID:31003867 MGI:6316415 MGI:6316551 NCBI chr 2:28,079,187...28,241,722
Ensembl chr 2:28,092,882...28,241,719 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      organic substance metabolic process 11557
        macromolecule metabolic process 9294
          nucleic acid metabolic process 2274
            nucleic acid phosphodiester bond hydrolysis 22
              deadenylation-independent decapping of nuclear-transcribed mRNA + 5
              meiotic DNA double-strand break formation + 8
              viral DNA cleavage involved in viral genome maturation 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular aromatic compound metabolic process 3032
          nucleobase-containing compound metabolic process 2783
            nucleic acid metabolic process 2274
              nucleic acid phosphodiester bond hydrolysis 22
                deadenylation-independent decapping of nuclear-transcribed mRNA + 5
                meiotic DNA double-strand break formation + 8
                viral DNA cleavage involved in viral genome maturation 0
paths to the root