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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol metabolic process
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Accession:GO:0090206 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.



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negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO (MGI:6101070|PMID:29033131) RGD PMID:29033131 MGI:6101070 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:1917954)
Ensembl
RGD
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:15473258)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15473258 GO_REF:0000024 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    negative regulation of biological process 5771
      negative regulation of metabolic process 3072
        negative regulation of small molecule metabolic process 126
          negative regulation of cholesterol metabolic process 9
            negative regulation of cholesterol biosynthetic process 8
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11721
      organic substance metabolic process 11216
        organic cyclic compound metabolic process 6225
          steroid metabolic process 365
            sterol metabolic process 169
              cholesterol metabolic process 154
                regulation of cholesterol metabolic process 48
                  negative regulation of cholesterol metabolic process 9
                    negative regulation of cholesterol biosynthetic process 8
paths to the root