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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of kidney development
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Accession:GO:0090183 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
Synonyms:related_synonym: regulation of nephrogenesis


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negative regulation of branching involved in ureteric bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:102780 (MGI:4949995|PMID:21281623)
(MGI:3525902|PMID:15634693)
GO_REF:0000024
(PMID:12141440), (PMID:17118062)
Ensembl
RGD
UniProt
PMID:12141440 PMID:15634693 PMID:17118062 PMID:21281623 GO_REF:0000024 GO_REF:0000107 MGI:3525902 MGI:4949995 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5315060|PMID:22194864)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22194864 GO_REF:0000024 GO_REF:0000107 MGI:5315060 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
negative regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12141440)
UniProt
Ensembl
RGD
PMID:12141440 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within ISO MGI:1857856 (MGI:4430439|PMID:20040500) RGD PMID:20040500 MGI:4430439 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
negative regulation of metanephric mesenchymal cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(MGI:4943654|PMID:19460854)
UniProt
RGD
PMID:19460854 GO_REF:0000024 MGI:4943654 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
negative regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3697513|PMID:16790474)
UniProt
RGD
PMID:16790474 GO_REF:0000024 MGI:3697513 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817
JBrowse link
positive regulation of branching involved in ureteric bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:18607644) RGD PMID:18607644 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in IMP PMID:17537984 UniProt PMID:17537984 RGD:1643596 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IMP PMID:17537984 UniProt PMID:17537984 RGD:1643596 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in IMP
ISO
PMID:17537984
(MGI:3808848|PMID:18607644)
RGD PMID:18607644 PMID:17537984 MGI:3808848, RGD:1643596 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IMP PMID:17537984 UniProt PMID:17537984 RGD:1643596 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IMP
IEA
ISO
IBA
IDA
PMID:17537984
GO_REF:0000107
(MGI:5284782|PMID:17229286)
PMID:21873635
PMID:17522159
(PMID:17229286), (PMID:8657307)
Ensembl
RGD
PMID:8657307 PMID:17229286 PMID:17537984 PMID:21873635 PMID:17522159 GO_REF:0000107 MGI:5284782, RGD:1643596, RGD:13792537, RGD:8656002 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISO (MGI:3714585|PMID:17522159)
MGI:88180 (MGI:3714585|PMID:17522159), (MGI:4949995|PMID:21281623)
RGD PMID:17522159 PMID:21281623 MGI:3714585 MGI:4949995 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Hoxb7 homeo box B7 involved_in ISO (MGI:3833510|PMID:17881463) RGD PMID:17881463 MGI:3833510 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISO (MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:5006869 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lhx1 LIM homeobox 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3613206|PMID:16216236)
UniProt
RGD
PMID:16216236 GO_REF:0000024 MGI:3613206 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Maged1 MAGE family member D1 involved_in ISO (MGI:3848096|PMID:19268530) RGD PMID:19268530 MGI:3848096 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364
JBrowse link
G Nog noggin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2446986|PMID:12141440), (MGI:3714585|PMID:17522159)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12141440 PMID:17522159 GO_REF:0000024 GO_REF:0000107 MGI:2446986 MGI:3714585 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325), (MGI:3833510|PMID:17881463), (MGI:5009394|PMID:17538188)
UniProt
RGD
PMID:17314325 PMID:17538188 PMID:17881463 GO_REF:0000024 MGI:3704067 MGI:3833510 MGI:5009394 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3603818 (MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:5563280 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Six1 SIX homeobox 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5009396|PMID:17300925)
MGI:88180 (MGI:4949995|PMID:21281623)
RGD PMID:17300925 PMID:21281623 MGI:4949995 MGI:5009396 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5009396|PMID:17300925) RGD PMID:17300925 MGI:5009396 NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
G Smo smoothened, frizzled class receptor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3611729|PMID:16396903)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16396903 GO_REF:0000024 GO_REF:0000107 MGI:3611729 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in IMP PMID:17537984 UniProt PMID:17537984 RGD:1643596 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:3611700|PMID:16291795) RGD PMID:16291795 MGI:3611700 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wnt2b Wnt family member 2B acts_upstream_of_or_within ISO (MGI:2150217|PMID:11507767) RGD PMID:11507767 MGI:2150217 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308
JBrowse link
positive regulation of glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2446986|PMID:12141440)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12141440 GO_REF:0000024 GO_REF:0000107 MGI:2446986 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
positive regulation of kidney development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:10021330)
UniProt
Ensembl
RGD
PMID:10021330 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:19270827 RGD:4892573 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Foxd1 forkhead box D1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3525902|PMID:15634693)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15634693 GO_REF:0000024 GO_REF:0000107 MGI:3525902 NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978
JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q04887 (MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q04886 (MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
positive regulation of metanephric cap mesenchymal cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:3830398|PMID:19161241)
UniProt
RGD
PMID:19161241 GO_REF:0000024 MGI:3830398 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (MGI:3808848|PMID:18607644) RGD PMID:18607644 MGI:3808848 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3697544|PMID:17047028)
UniProt
RGD
PMID:17047028 GO_REF:0000024 MGI:3697544 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Ret ret proto-oncogene involved_in ISO (MGI:3697544|PMID:17047028) RGD PMID:17047028 MGI:3697544 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
positive regulation of metanephric ureteric bud development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:62488|PMID:8395349)
UniProt
RGD
PMID:8395349 GO_REF:0000024 MGI:62488 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
positive regulation of ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3822373|PMID:19112489)
UniProt
RGD
PMID:19112489 GO_REF:0000024 MGI:3822373 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8657307)
UniProt
Ensembl
RGD
PMID:8657307 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Six1 SIX homeobox 1 involved_in ISO (MGI:5009396|PMID:17300925) RGD PMID:17300925 MGI:5009396 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5009396|PMID:17300925) RGD PMID:17300925 MGI:5009396 NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
regulation of branching involved in ureteric bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Six2 SIX homeobox 2 involved_in ISO (MGI:3691408|PMID:17036046) RGD PMID:17036046 MGI:3691408 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
regulation of ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IDA PMID:19112489 UniProt PMID:19112489 RGD:8656008 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
renal vesicle induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox8 SRY-box transcription factor 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2150217|PMID:11507767)
Ensembl
RGD
PMID:11507767 GO_REF:0000107 MGI:2150217 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      regulation of developmental process 2663
        regulation of kidney development 35
          negative regulation of kidney development + 4
          positive regulation of kidney development + 11
          regulation of branching involved in ureteric bud morphogenesis + 25
          regulation of glomerulus development + 5
          regulation of mesonephros development + 5
          regulation of metanephros development + 5
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      anatomical structure development 6196
        multicellular organism development 5633
          system development 5301
            urogenital system development 436
              renal system development 387
                kidney development 374
                  regulation of kidney development 35
                    negative regulation of kidney development + 4
                    positive regulation of kidney development + 11
                    regulation of branching involved in ureteric bud morphogenesis + 25
                    regulation of glomerulus development + 5
                    regulation of mesonephros development + 5
                    regulation of metanephros development + 5
paths to the root