ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of sphingolipid biosynthetic process
Accession: GO:0090155
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Definition: Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms: related_synonym: negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis
alt_id: GO:0090157
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Abca2
ATP binding cassette subfamily A member 2
involved_in
ISO IEA IMP
(PMID:24201375) GO_REF:0000107
RGD Ensembl
PMID:24201375 , PMID:24201375
GO_REF:0000107, RGD:14697729
NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
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Atg7
autophagy related 7
acts_upstream_of_or_within
ISO
MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431)
RGD
PMID:25332431
MGI:5613260
NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
G
Ormdl1
ORMDL sphingolipid biosynthesis regulator 1
involved_in
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
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Ormdl2
ORMDL sphingolipid biosynthesis regulator 2
involved_in
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
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Ormdl3
ORMDL sphingolipid biosynthesis regulator 3
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000107 (MGI:5638294|PMID:25691431) PMID:21873635
Ensembl RGD
PMID:25691431 , PMID:21873635
GO_REF:0000107 MGI:5638294 , RGD:13792537
NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
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Sphk1
sphingosine kinase 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (MGI:6294167|PMID:16118219) (PMID:16118219)
UniProt Ensembl RGD
PMID:16118219
GO_REF:0000024 GO_REF:0000107 MGI:6294167
NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
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