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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sphingolipid biosynthetic process
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Accession:GO:0090155 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:related_synonym: negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis
 alt_id: GO:0090157



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negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO
IEA
IMP
(PMID:24201375)
GO_REF:0000107
RGD
Ensembl
PMID:24201375 PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:25691431)
(MGI:5638294|PMID:25691431)
Ensembl
RGD
PMID:25691431 PMID:21873635 GO_REF:0000107 MGI:5638294, RGD:13792537 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)
UniProt
Ensembl
RGD
PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      nitrogen compound metabolic process 10013
        negative regulation of nitrogen compound metabolic process 2473
          negative regulation of sphingolipid biosynthetic process 6
            negative regulation of ceramide biosynthetic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      primary metabolic process 10558
        lipid metabolic process 1411
          cellular lipid metabolic process 1040
            membrane lipid metabolic process 196
              sphingolipid metabolic process 150
                sphingolipid biosynthetic process 100
                  regulation of sphingolipid biosynthetic process 14
                    negative regulation of sphingolipid biosynthetic process 6
                      negative regulation of ceramide biosynthetic process + 4
paths to the root