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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sphingolipid biosynthetic process
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Accession:GO:0090155 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:related_synonym: negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis
 alt_id: GO:0090157


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negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO
IEA
IMP
(PMID:24201375)
GO_REF:0000107
RGD
Ensembl
PMID:24201375, PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
(MGI:5638294|PMID:25691431)
PMID:21873635
Ensembl
RGD
PMID:25691431, PMID:21873635 GO_REF:0000107 MGI:5638294, RGD:13792537 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)
UniProt
Ensembl
RGD
PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      nitrogen compound metabolic process 10102
        negative regulation of nitrogen compound metabolic process 2498
          negative regulation of sphingolipid biosynthetic process 6
            negative regulation of ceramide biosynthetic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      primary metabolic process 10642
        lipid metabolic process 1364
          cellular lipid metabolic process 1014
            membrane lipid metabolic process 189
              sphingolipid metabolic process 143
                sphingolipid biosynthetic process 90
                  regulation of sphingolipid biosynthetic process 14
                    negative regulation of sphingolipid biosynthetic process 6
                      negative regulation of ceramide biosynthetic process + 4
paths to the root