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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sphingolipid biosynthetic process
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Accession:GO:0090155 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:related_synonym: negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis
 alt_id: GO:0090157



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negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO
IEA
IMP
(PMID:24201375)
GO_REF:0000107
RGD
Ensembl
PMID:24201375 PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5638294|PMID:25691431)
(PMID:25691431)
Ensembl
RGD
PMID:25691431 GO_REF:0000107 MGI:5638294 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:16118219)
(MGI:6294167|PMID:16118219)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    metabolic process 12191
      nitrogen compound metabolic process 10416
        negative regulation of nitrogen compound metabolic process 2572
          negative regulation of sphingolipid biosynthetic process 6
            negative regulation of ceramide biosynthetic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19874
    metabolic process 12191
      primary metabolic process 10954
        lipid metabolic process 1449
          cellular lipid metabolic process 1054
            membrane lipid metabolic process 200
              sphingolipid metabolic process 151
                sphingolipid biosynthetic process 101
                  regulation of sphingolipid biosynthetic process 15
                    negative regulation of sphingolipid biosynthetic process 6
                      negative regulation of ceramide biosynthetic process + 4
paths to the root