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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mitochondrial fission
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Accession:GO:0090140 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
Synonyms:exact_synonym: regulation of mitochondrial division



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regulation of mitochondrial fission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (PMID:29059164)
(MGI:6383355|PMID:29059164)
RGD PMID:29059164 MGI:6383355 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IMP RGD PMID:16120318 RGD:2316230 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Inf2 inverted formin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23349293)
GO_REF:0000107
RGD
Ensembl
PMID:23349293 GO_REF:0000107 NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:16874301), (PMID:17606867) RGD PMID:16874301 PMID:17606867 NCBI chr 1:234,931,137...234,953,849
Ensembl chr 1:234,931,271...234,952,632
JBrowse link
G Myo19 myosin XIX involved_in ISO (PMID:25447992) RGD PMID:25447992 NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450
JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:26122121) RGD PMID:26122121 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
JBrowse link
G Tmem135 transmembrane protein 135 involved_in ISS
ISO
GO_REF:0000024
(MGI:5811545|PMID:27863209)
UniProt
RGD
PMID:27863209 GO_REF:0000024 MGI:5811545 NCBI chr 1:143,006,343...143,279,824
Ensembl chr 1:143,006,344...143,221,171
JBrowse link
negative regulation of mitochondrial fission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau involved_in IEA
ISO
GO_REF:0000107
(PMID:22920254)
Ensembl
RGD
PMID:22920254 GO_REF:0000107 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mfn1 mitofusin 1 IMP RGD PMID:18832378 RGD:12738368 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28478070 RGD:12910733 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:29182484) RGD PMID:29182484 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:23449689 RGD:10059694 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G RGD1311251 similar to RIKEN cDNA 4930550C14 involved_in ISS
ISO
GO_REF:0000024
(MGI:6200588|PMID:30059978)
UniProt
RGD
PMID:30059978 GO_REF:0000024 MGI:6200588 NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748
JBrowse link
positive regulation of mitochondrial fission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A involved_in IEA
ISO
GO_REF:0000107
(PMID:21822277)
Ensembl
RGD
PMID:21822277 GO_REF:0000107 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddhd1 DDHD domain containing 1 acts_upstream_of_or_within ISO (PMID:24599962) RGD PMID:24599962 NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
JBrowse link
G Ddhd2 DDHD domain containing 2 acts_upstream_of_or_within ISO (MGI:5581382|PMID:24599962) RGD PMID:24599962 MGI:5581382 NCBI chr16:66,319,469...66,349,025
Ensembl chr16:66,319,466...66,349,023
JBrowse link
G Dnm1l dynamin 1-like involved_in IMP
ISO
(PMID:19279012) RGD PMID:19279012 PMID:17443673 RGD:12738363 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in IMP
ISS
ISO
GO_REF:0000024
(PMID:23283981)
UniProt
RGD
PMID:23283981 PMID:17443673 PMID:15979461 GO_REF:0000024, RGD:12738363, RGD:12738370 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:20103533) RGD PMID:20103533 NCBI chr 1:234,931,137...234,953,849
Ensembl chr 1:234,931,271...234,952,632
JBrowse link
G Mcu mitochondrial calcium uniporter involved_in ISO (PMID:28388446) RGD PMID:28388446 NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110
JBrowse link
G Mff mitochondrial fission factor involved_in IMP
ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:23283981), (PMID:23530241)
UniProt
RGD
PMID:23283981 PMID:23530241 PMID:23867156 PMID:21873635 GO_REF:0000024, RGD:12879458, RGD:13792537 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mief1 mitochondrial elongation factor 1 involved_in ISO
IBA
ISS
(PMID:23283981), (PMID:23530241)
(MGI:5508698|PMID:23283981)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23283981 PMID:23530241 PMID:21873635 GO_REF:0000024 MGI:5508698, RGD:13792537 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
JBrowse link
G Mief2 mitochondrial elongation factor 2 involved_in IBA
ISO
PMID:21873635
(MGI:5508698|PMID:23283981)
(PMID:23283981), (PMID:23530241)
RGD PMID:23283981 PMID:23530241 PMID:21873635 MGI:5508698, RGD:13792537 NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:19407830) RGD PMID:19407830 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Pgam5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:21613270 PMID:21873635 RGD:12903967, RGD:13792537 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Rala RAS like proto-oncogene A involved_in ISO
ISS
(PMID:21822277)
GO_REF:0000024
RGD
UniProt
PMID:21822277 GO_REF:0000024 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Ralbp1 ralA binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21822277)
UniProt
RGD
PMID:21822277 GO_REF:0000024 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Spire1 spire-type actin nucleation factor 1 involved_in ISO (PMID:26305500)
(MGI:5698602|PMID:26305500)
RGD PMID:26305500 MGI:5698602 NCBI chr18:61,041,290...61,171,670
Ensembl chr18:61,041,290...61,171,899
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26618722) RGD PMID:26618722 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    regulation of biological process 12770
      regulation of developmental process 2665
        regulation of anatomical structure morphogenesis 1003
          regulation of mitochondrial fission 33
            negative regulation of mitochondrial fission 8
            positive regulation of mitochondrial fission 21
Path 2
Term Annotations click to browse term
  biological_process 19504
    biological regulation 13513
      regulation of biological process 12770
        regulation of cellular process 12230
          regulation of cellular component organization 2453
            regulation of organelle organization 1159
              regulation of mitochondrion organization 139
                regulation of mitochondrial fission 33
                  negative regulation of mitochondrial fission 8
                  positive regulation of mitochondrial fission 21
paths to the root