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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor-mediated endocytosis involved in cholesterol transport
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Accession:GO:0090118 term browser browse the term
Definition:A receptor-mediated endocytosis process involved in intracellular cholesterol transport.
Synonyms:related_synonym: receptor-mediated endocytosis involved in intracellular cholesterol transport;   receptor-mediated endocytosis of LDL;   receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport;   receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport



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receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IBA
(PMID:6299582)
PMID:21873635
RGD PMID:6299582 PMID:21873635 RGD:13792537 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:4123883 (MGI:4413421|PMID:18948618)
PMID:21873635
RGD PMID:18948618 PMID:21873635 MGI:4413421, RGD:13792537 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) RGD PMID:23285084 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) RGD PMID:26520906 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    localization 5475
      cellular localization 3497
        intracellular transport 1560
          receptor-mediated endocytosis involved in cholesterol transport 8
            negative regulation of receptor-mediated endocytosis involved in cholesterol transport 4
            positive regulation of receptor-mediated endocytosis involved in cholesterol transport 2
            regulation of receptor-mediated endocytosis involved in cholesterol transport + 6
Path 2
Term Annotations click to browse term
  biological_process 18734
    localization 5475
      establishment of localization 4825
        transport 4663
          organic substance transport 2480
            lipid transport 448
              sterol transport 137
                intracellular sterol transport 34
                  intracellular cholesterol transport 31
                    receptor-mediated endocytosis involved in cholesterol transport 8
                      negative regulation of receptor-mediated endocytosis involved in cholesterol transport 4
                      positive regulation of receptor-mediated endocytosis involved in cholesterol transport 2
                      regulation of receptor-mediated endocytosis involved in cholesterol transport + 6
paths to the root