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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
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Accession:GO:0090101 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms:exact_synonym: negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway



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negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSTL3 follistatin like 3 involved_in ISO (PMID:17878677) UniProt PMID:17878677
negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chr 9:14,552,062...14,559,632
Ensembl chr 9:15,063,766...15,066,776
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:16720724) BHF-UCL PMID:16720724 NCBI chr20:1,519,330...1,548,473 JBrowse link
G FST follistatin involved_in ISO (PMID:12702211)
(PMID:11948405), (PMID:12697670)
UniProt PMID:11948405 PMID:12697670 PMID:12702211 NCBI chr 5:60,544,495...60,550,516 JBrowse link
G FSTL3 follistatin like 3 involved_in ISO (PMID:11948405), (PMID:12697670) UniProt PMID:11948405 PMID:12697670
G IGSF1 immunoglobulin superfamily member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:120,406,725...120,422,636
Ensembl chr  X:130,714,061...130,729,963
JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,668,368...23,747,369
Ensembl chr12:24,172,749...24,252,314
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISO (MGI:1353670|PMID:10681527) UniProt PMID:10681527 MGI:1353670 NCBI chr 7:69,943,704...71,395,176
Ensembl chr 7:83,758,512...84,760,872
JBrowse link
G SKI SKI proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:16720724) BHF-UCL PMID:16720724 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SYNJ2BP synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) UniProt PMID:16648306 MGI:3623710 NCBI chr14:50,958,861...51,009,395
Ensembl chr14:69,835,548...69,879,537
JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22729085) Ensembl
MGI
PMID:22729085 GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21743293) ARUK-UCL
Ensembl
PMID:21743293 GO_REF:0000107 NCBI chr10:28,833,690...28,839,164
Ensembl chr10:29,187,857...29,193,324
JBrowse link
G BMPER BMP binding endothelial regulator acts_upstream_of_or_within ISO (PMID:12897139) MGI PMID:12897139 NCBI chr 7:34,508,583...34,759,860
Ensembl chr 7:34,903,178...35,152,110
JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:15657086) BHF-UCL PMID:15657086 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9431803), (PMID:9501024) Ensembl
MGI
PMID:9431803 PMID:9501024 GO_REF:0000107 NCBI chr 9:14,552,062...14,559,632
Ensembl chr 9:15,063,766...15,066,776
JBrowse link
G CHRD chordin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15780974), (PMID:19850029) Ensembl
MGI
TreeGrafter
PMID:15780974 PMID:19850029 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573
JBrowse link
G CHRDL1 chordin like 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23676271) Ensembl
MGI
TreeGrafter
PMID:23676271 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:99,781,730...99,915,778
Ensembl chr  X:110,251,525...110,375,289
JBrowse link
G CHRDL2 chordin like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14660436) TreeGrafter
MGI
PMID:14660436 GO_REF:0000118 NCBI chr11:69,769,476...69,804,480
Ensembl chr11:73,073,738...73,096,068
JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21743293) ARUK-UCL
Ensembl
PMID:21743293 GO_REF:0000107 NCBI chr2A:36,384,964...36,580,214
Ensembl chr2A:37,147,108...37,340,537
JBrowse link
G CTDSPL2 CTD small phosphatase like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25100727) Ensembl
MGI
PMID:25100727 GO_REF:0000107 NCBI chr15:23,384,416...23,483,508
Ensembl chr15:41,554,276...41,654,736
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) BHF-UCL PMID:15466485 MGI:3055649 NCBI chr19:12,529,830...12,536,052 JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:59,382,156...59,387,100
Ensembl chr2B:176,839,721...176,843,909
JBrowse link
G FSTL3 follistatin like 3 involved_in
acts_upstream_of_or_within
ISO (PMID:17878677)
(PMID:11010968)
UniProt
MGI
PMID:11010968 PMID:17878677
G FZD1 frizzled class receptor 1 acts_upstream_of_or_within ISO (PMID:14627707) MGI PMID:14627707 NCBI chr 7:83,269,906...83,277,608 JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,813,288...7,819,418
Ensembl chr12:7,972,907...7,979,815
JBrowse link
G GPR155 G protein-coupled receptor 155 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:61,710,094...61,764,434
Ensembl chr2B:179,166,785...179,218,301
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISO (PMID:16816361), (PMID:27036124)
(PMID:17522159)
(PMID:15539560)
UniProt
MGI
BHF-UCL
PMID:15539560 PMID:16816361 PMID:17522159 PMID:27036124 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:216,037,977...216,163,020
Ensembl chr 1:221,026,605...221,027,111
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:12874272) UniProt PMID:12874272 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G HJV hemojuvelin BMP co-receptor acts_upstream_of_or_within ISO (PMID:20065295) MGI PMID:20065295 NCBI chr 1:121,738,465...121,742,743
Ensembl chr 1:113,926,383...113,930,761
JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14973287) Ensembl
MGI
PMID:14973287 GO_REF:0000107 NCBI chr10:119,030,409...119,083,682
Ensembl chr10:122,441,098...122,494,733
JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:8,335,529...8,374,510 JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr12:23,668,368...23,747,369
Ensembl chr12:24,172,749...24,252,314
JBrowse link
G LRP2 LDL receptor related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:56,407,871...56,640,471
Ensembl chr2B:173,873,767...174,103,697
JBrowse link
G MTMR4 myotubularin related protein 4 involved_in ISO (PMID:23150675) FlyBase PMID:23150675 NCBI chr17:52,564,455...52,592,899
Ensembl chr17:57,418,229...57,446,545
JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:16801560) MGI PMID:16801560 NCBI chr12:7,913,037...7,919,715 JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23676271) Ensembl
MGI
PMID:23676271 GO_REF:0000107 NCBI chr 1:18,599,121...18,613,305
Ensembl chr 1:19,641,279...19,656,431
JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19852960)
(PMID:15110716), (PMID:15975920), (PMID:18462699), (PMID:19850029)
(PMID:16712836)
Ensembl
MGI
TreeGrafter
UniProt
InterPro
PMID:15110716 PMID:15975920 PMID:16712836 PMID:18462699 PMID:19850029 More... GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092
JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A acts_upstream_of_or_within ISO (PMID:25100727) MGI PMID:25100727 NCBI chr14:40,853,227...40,906,044
Ensembl chr14:59,117,020...59,162,928
JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19850029) Ensembl
MGI
PMID:19850029 GO_REF:0000107 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SKI SKI proto-oncogene involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21937600) Ensembl
MGI
TreeGrafter
PMID:21937600 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080
JBrowse link
G SKIL SKI like proto-oncogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181
JBrowse link
G SKOR1 SKI family transcriptional corepressor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:46,722,712...46,787,689 JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO (PMID:21937600) MGI PMID:21937600 NCBI chr18:40,594,124...40,639,720 JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in
acts_upstream_of_or_within
ISO (PMID:17438144)
(PMID:19850029)
BHF-UCL
MGI
PMID:17438144 PMID:19850029 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:58,638,995...58,759,443
Ensembl chr17:63,731,386...63,809,298
JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432
JBrowse link
G SOST sclerostin acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14633986)
(PMID:17002572)
MGI
TreeGrafter
Ensembl
PMID:14633986 PMID:17002572 GO_REF:0000107 GO_REF:0000118 NCBI chr17:13,639,088...13,644,152
Ensembl chr17:13,804,374...13,809,432
JBrowse link
G SOSTDC1 sclerostin domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16179481)
(PMID:14623234), (PMID:16179481)
Ensembl
MGI
TreeGrafter
PMID:14623234 PMID:16179481 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:17,193,531...17,229,769
Ensembl chr 7:16,443,703...16,448,076
Ensembl chr 7:16,443,703...16,448,076
JBrowse link
G SPART spartin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22619377) Ensembl
MGI
TreeGrafter
PMID:22619377 GO_REF:0000107 GO_REF:0000118 NCBI chr13:17,514,720...17,582,011
Ensembl chr13:35,945,938...35,989,774
JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:17919533) MGI PMID:17919533 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281
JBrowse link
G TMEM53 transmembrane protein 53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,955,734...43,977,107
Ensembl chr 1:45,305,359...45,343,109
JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19751239) Ensembl
MGI
PMID:19751239 GO_REF:0000107 NCBI chr22:17,979,094...18,032,590
Ensembl chr22:35,815,051...35,859,940
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:38,669,652...38,692,037
Ensembl chr2B:155,933,842...155,956,382
JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11163184) Ensembl
MGI
PMID:11163184 GO_REF:0000107 NCBI chr17:44,953,343...44,957,465
Ensembl chr17:49,825,646...49,826,683
JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,043,031...88,163,804
Ensembl chr 1:123,095,244...123,210,355
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12665593)
(PMID:15780974)
Ensembl
MGI
PMID:12665593 PMID:15780974 GO_REF:0000107 NCBI chr18:4,883,688...4,950,963
Ensembl chr18:7,164,091...7,229,271
JBrowse link
G VWC2 von Willebrand factor C domain containing 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 7:50,412,363...50,562,837
Ensembl chr 7:50,661,384...50,800,814
JBrowse link
G VWC2L von Willebrand factor C domain containing 2 like involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19852960) Ensembl
MGI
TreeGrafter
PMID:19852960 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:101,666,338...101,835,393
Ensembl chr2B:220,143,121...220,330,678
JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18351662) Ensembl
MGI
PMID:18351662 GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DACT2 dishevelled binding antagonist of beta catenin 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 6:166,295,983...166,308,361
Ensembl chr 6:171,237,795...171,247,797
Ensembl chr 6:171,237,795...171,247,797
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) BHF-UCL PMID:15466485 MGI:3055649 NCBI chr19:12,529,830...12,536,052 JBrowse link
G LOC100969502 left-right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) UniProt PMID:15062104 MGI:3042530 NCBI chr 1:201,347,411...201,351,295
Ensembl chr 1:206,348,419...206,350,787
JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN3 cellular communication network factor 3 involved_in
acts_upstream_of_positive_effect
IEA
ISO
(MGI:5504324|PMID:23653360) Ensembl
UniProt
PMID:23653360 GO_REF:0000107 MGI:5504324 NCBI chr 8:116,105,935...116,114,241
Ensembl chr 8:118,855,445...118,865,039
JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,142,312...44,159,395
Ensembl chr15:62,425,780...62,441,214
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) HGNC-UCL PMID:14612439 NCBI chr19:36,636,855...36,638,308 JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525
JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in ISO (MGI:5486566|PMID:12646588) UniProt PMID:12646588 MGI:5486566 NCBI chr11:60,931,592...60,933,317 JBrowse link
G GDF15 growth differentiation factor 15 involved_in ISO (PMID:25893289) UniProt PMID:25893289 NCBI chr19:17,864,840...17,867,883
Ensembl chr19:18,835,216...18,838,470
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:11,213,870...11,230,619 JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:669,862...1,110,558
Ensembl chr18:2,845,198...2,879,363
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G NOG noggin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092
JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28467929), (PMID:31023188) BHF-UCL PMID:28467929 PMID:31023188 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G SKI SKI proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:17438144)
(MGI:3836072|PMID:18952608)
(PMID:16601693)
BHF-UCL PMID:16601693 PMID:17438144 PMID:18952608 MGI:3836072 NCBI chr18:42,306,324...42,337,214 JBrowse link
G TBX20 T-box transcription factor 20 acts_upstream_of_or_within ISO (PMID:19661464) MGI PMID:19661464 NCBI chr 7:35,855,969...35,878,533 JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G UCMA upper zone of growth plate and cartilage matrix associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:13,223,897...13,237,230
Ensembl chr10:13,196,867...13,209,494
JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:154,308,573...154,552,029
Ensembl chr 3:162,357,876...162,604,358
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054
JBrowse link
G ADAMTSL2 ADAMTS like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25762570) Ensembl
MGI
PMID:25762570 GO_REF:0000107 NCBI chr 9:104,658,540...104,698,854
Ensembl chr 9:133,269,369...133,309,602
JBrowse link
G ASPN asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr10:28,833,690...28,839,164
Ensembl chr10:29,187,857...29,193,324
JBrowse link
G BCL9L BCL9 like involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr11:113,735,852...113,765,811
Ensembl chr11:117,666,995...117,678,598
JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:28467929) ARUK-UCL
Ensembl
PMID:28467929 GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G CAV2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21832243) Ensembl
MGI
PMID:21832243 GO_REF:0000107 NCBI chr 7:108,254,074...108,480,716
Ensembl chr 7:121,168,579...121,177,415
JBrowse link
G CD109 CD109 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414
JBrowse link
G CDH3 cadherin 3 involved_in
acts_upstream_of_or_within_negative_effect
IEA
ISO
(PMID:22696062) Ensembl
UniProt
PMID:22696062 GO_REF:0000107 NCBI chr16:49,015,115...49,071,903
Ensembl chr16:68,407,625...68,465,287
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16079159) Ensembl
MGI
PMID:16079159 GO_REF:0000107 NCBI chr12:102,035,480...102,340,084
Ensembl chr12:105,431,075...105,731,172
JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:3768618 NCBI chr18:2,051,880...2,075,909 JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,142,312...44,159,395
Ensembl chr15:62,425,780...62,441,214
JBrowse link
G CRIPTO cripto, EGF-CFC family member acts_upstream_of_or_within ISO (PMID:17991893) MGI PMID:17991893 NCBI chr 3:46,473,282...46,478,454
Ensembl chr 3:47,577,949...47,583,126
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (PMID:14721776) MGI PMID:14721776 NCBI chr19:12,529,830...12,536,052 JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) HGNC-UCL PMID:14612439 NCBI chr19:36,636,855...36,638,308 JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525
JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in ISO (MGI:5486566|PMID:12646588) UniProt PMID:12646588 MGI:5486566 NCBI chr11:60,931,592...60,933,317 JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) FlyBase PMID:11583628 NCBI chr20:1,519,330...1,548,473 JBrowse link
G GDF15 growth differentiation factor 15 involved_in ISO (PMID:25893289) GO_Central PMID:25893289 NCBI chr19:17,864,840...17,867,883
Ensembl chr19:18,835,216...18,838,470
JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within ISO (PMID:20530870) MGI PMID:20530870 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 acts_upstream_of_or_within ISO (PMID:17991893) MGI PMID:17991893 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14973287) Ensembl
MGI
PMID:14973287 GO_REF:0000107 NCBI chr10:119,030,409...119,083,682
Ensembl chr10:122,441,098...122,494,733
JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:8,335,529...8,374,510 JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,023,622...57,098,869
Ensembl chr 3:58,240,835...58,309,409
JBrowse link
G INTS9 integrator complex subunit 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:28,049,858...28,173,046
Ensembl chr 8:25,247,565...25,369,907
JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr18:669,862...1,110,558
Ensembl chr18:2,845,198...2,879,363
JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,668,368...23,747,369
Ensembl chr12:24,172,749...24,252,314
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G MECOM MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) UniProt PMID:15897867 NCBI chr 3:166,099,530...166,677,739
Ensembl chr 3:174,154,814...174,731,252
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in ISO (PMID:19293183) UniProt PMID:19293183
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16103213) Ensembl
MGI
PMID:16103213 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062
JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (PMID:16103213) MGI PMID:16103213 NCBI chr18:50,826,110...50,882,127 JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486
JBrowse link
G PBLD phenazine biosynthesis like protein domain containing involved_in
acts_upstream_of_or_within_positive_effect
IEA
ISO
(PMID:23687415) Ensembl
UniProt
PMID:23687415 GO_REF:0000107 NCBI chr10:64,766,873...64,817,055
Ensembl chr10:67,077,445...67,126,980
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:17327236) UniProt PMID:17327236 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PEG10 paternally expressed 10 involved_in ISO (PMID:15611116) HGNC-UCL PMID:15611116 NCBI chr 7:86,606,249...86,619,580 JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31611175) ARUK-UCL
Ensembl
PMID:31611175 GO_REF:0000107 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within
involved_in
ISO (PMID:28467929)
(PMID:31023188)
ARUK-UCL
BHF-UCL
PMID:28467929 PMID:31023188 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,853,227...40,906,044
Ensembl chr14:59,117,020...59,162,928
JBrowse link
G PRDM16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:14656887)
(PMID:20007998)
UniProt
MGI
Ensembl
PMID:14656887 PMID:20007998 GO_REF:0000107 NCBI chr 1:1,730,122...2,100,636
Ensembl chr 1:2,981,667...3,234,251
JBrowse link
G RASL11B RAS like family 11 member B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15239668) Ensembl
MGI
PMID:15239668 GO_REF:0000107 NCBI chr 4:71,101,709...71,106,235
Ensembl chr 4:77,655,461...77,659,972
JBrowse link
G RYR1 ryanodine receptor 1 ISO RGD PMID:32619649 RGD:329845531 NCBI chr19:35,527,466...35,685,446
Ensembl chr19:44,106,036...44,256,327
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SKI SKI proto-oncogene acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15312649)
(PMID:21937600)
MGI
Ensembl
PMID:15312649 PMID:21937600 GO_REF:0000107 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080
JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15677329) Ensembl
MGI
PMID:15677329 GO_REF:0000107 NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181
JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:16200078)
(PMID:21937600)
UniProt
MGI
PMID:16200078 PMID:21937600 NCBI chr18:40,594,124...40,639,720 JBrowse link
G SLC2A10 solute carrier family 2 member 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16550171), (PMID:26376865) ARUK-UCL
Ensembl
PMID:16550171 PMID:26376865 GO_REF:0000107 NCBI chr20:43,043,801...43,068,304
Ensembl chr20:44,128,837...44,153,148
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:11278251), (PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479)
(PMID:16601693), (PMID:21791611)
BHF-UCL
UniProt
PMID:9256479 PMID:11278251 PMID:12151385 PMID:16601693 PMID:17438144 More... NCBI chr18:42,306,324...42,337,214 JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,638,995...58,759,443
Ensembl chr17:63,731,386...63,809,298
JBrowse link
G SNX1 sorting nexin 1 acts_upstream_of_or_within ISO (PMID:15239668) MGI PMID:15239668 NCBI chr15:43,048,974...43,096,544
Ensembl chr15:61,340,352...61,382,700
JBrowse link
G SNX25 sorting nexin 25 involved_in ISO (MGI:5545984|PMID:21266196)
(PMID:21266196)
UniProt PMID:21266196 MGI:5545984 NCBI chr 4:177,377,302...177,529,601
Ensembl chr 4:189,631,239...189,746,590
JBrowse link
G SNX6 sorting nexin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,319,526...15,388,326
Ensembl chr14:33,511,019...33,576,705
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840
JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr19:35,482,436...35,490,745
Ensembl chr19:44,054,053...44,061,962
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G STRAP serine/threonine kinase receptor associated protein acts_upstream_of_positive_effect
acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23687415)
(PMID:9856985)
UniProt
MGI
Ensembl
PMID:9856985 PMID:23687415 GO_REF:0000107 NCBI chr12:15,883,512...15,904,778
Ensembl chr12:16,279,956...16,300,746
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15657445) Ensembl
MGI
PMID:15657445 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,533,441...26,682,964
Ensembl chr12:26,808,337...26,954,099
JBrowse link
G VASN vasorin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:3,298,836...3,310,548
Ensembl chr16:4,475,506...4,477,527
JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:154,308,573...154,552,029
Ensembl chr 3:162,357,876...162,604,358
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO (PMID:21054789) UniProt PMID:21054789
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569
JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16601693) Ensembl
MGI
PMID:16601693 GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in ISO (PMID:25514493) UniProt PMID:25514493 NCBI chr19:3,066,554...3,090,285 JBrowse link
G ZNF451 zinc finger protein 451 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,647,589...56,728,231
Ensembl chr 6:58,279,387...58,358,935
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:216,037,977...216,163,020
Ensembl chr 1:221,026,605...221,027,111
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:18,599,121...18,613,305
Ensembl chr 1:19,641,279...19,656,431
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,552,062...14,559,632
Ensembl chr 9:15,063,766...15,066,776
JBrowse link
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,599,121...18,613,305
Ensembl chr 1:19,641,279...19,656,431
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAND5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) BHF-UCL PMID:15466485 MGI:3055649 NCBI chr19:12,529,830...12,536,052 JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602
JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,984,797...194,007,173
Ensembl chr 3:203,920,334...203,948,506
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    negative regulation of biological process 5559
      negative regulation of response to stimulus 1754
        negative regulation of signal transduction 1362
          negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 134
            negative regulation of BMP signaling pathway + 58
            negative regulation of SMAD protein signal transduction 23
            negative regulation of activin receptor signaling pathway + 16
            negative regulation of anti-Mullerian hormone signaling pathway 0
            negative regulation of transforming growth factor beta receptor signaling pathway + 82
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        signaling 5935
          signal transduction 5440
            cell surface receptor signaling pathway 2631
              enzyme-linked receptor protein signaling pathway 947
                cell surface receptor protein serine/threonine kinase signaling pathway 365
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 257
                    negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 134
                      negative regulation of BMP signaling pathway + 58
                      negative regulation of SMAD protein signal transduction 23
                      negative regulation of activin receptor signaling pathway + 16
                      negative regulation of anti-Mullerian hormone signaling pathway 0
                      negative regulation of transforming growth factor beta receptor signaling pathway + 82
paths to the root