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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
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Accession:GO:0090101 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms:exact_synonym: negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway


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negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fstl3 follistatin like 3 involved_in ISO (PMID:17878677) RGD PMID:17878677 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:9660951)
(MGI:1858315|PMID:10748465)
RGD PMID:9660951 PMID:10748465 MGI:1858315 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Fst follistatin involved_in IBA
ISO
PMID:21873635
(PMID:11948405), (PMID:12697670), (PMID:12702211)
RGD PMID:11948405 PMID:12697670 PMID:12702211, PMID:21873635 RGD:13792537 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Fstl3 follistatin like 3 involved_in ISO
IBA
(PMID:11948405), (PMID:12697670)
PMID:21873635
RGD PMID:11948405 PMID:12697670, PMID:21873635 RGD:13792537 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 involved_in ISO (PMID:11266516) RGD PMID:11266516 NCBI chr  X:136,792,637...136,808,107
Ensembl chr  X:136,792,643...136,807,885
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:62,976,671...63,045,860
Ensembl chr 7:62,996,336...63,045,728
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1353670|PMID:10681527)
UniProt
RGD
PMID:10681527 GO_REF:0000024 MGI:1353670 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Mir210 microRNA 210 acts_upstream_of_or_within ISO (MGI:3851892|PMID:19520079) RGD PMID:19520079 MGI:3851892 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Ski SKI proto-oncogene involved_in ISO (PMID:14699069) RGD PMID:14699069 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:105,224,166...105,261,549
Ensembl chr 6:105,224,166...105,261,549
JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bmper BMP-binding endothelial regulator acts_upstream_of_or_within ISO (MGI:2670247|PMID:12897139) RGD PMID:12897139 MGI:2670247 NCBI chr 8:24,369,916...24,615,484
Ensembl chr 8:24,369,916...24,615,479
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:15657086) RGD PMID:15657086 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist acts_upstream_of_or_within ISO (MGI:1101446|PMID:9431803), (MGI:1197794|PMID:9501024) RGD PMID:9431803 PMID:9501024 MGI:1101446 MGI:1197794 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Chrd chordin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3577114|PMID:15780974), (MGI:4429763|PMID:19850029)
(PMID:11472837)
Ensembl
RGD
PMID:11472837 PMID:15780974 PMID:19850029 GO_REF:0000107 MGI:3577114 MGI:4429763 NCBI chr11:83,858,503...83,867,543
Ensembl chr11:83,858,503...83,867,203
JBrowse link
G Chrdl1 chordin-like 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5492288|PMID:23676271)
Ensembl
RGD
PMID:23676271 GO_REF:0000107 MGI:5492288 NCBI chr  X:114,554,359...114,658,975
Ensembl chr  X:114,554,359...114,658,931
JBrowse link
G Chrdl2 chordin-like 2 acts_upstream_of_or_within ISO (MGI:2683044|PMID:14660436) RGD PMID:14660436 MGI:2683044 NCBI chr 1:165,008,997...165,036,431
Ensembl chr 1:165,008,912...165,036,435
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Ctdspl2 CTD small phosphatase like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5613417|PMID:25100727)
Ensembl
RGD
PMID:25100727 GO_REF:0000107 MGI:5613417 NCBI chr 3:113,906,803...113,957,289
Ensembl chr 3:113,918,629...113,960,101
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dlx1 distal-less homeobox 1 involved_in ISO
ISS
IEA
(PMID:14671321)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:14671321 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Fstl3 follistatin like 3 involved_in
acts_upstream_of_or_within
ISO (PMID:17878677)
(MGI:1929020|PMID:11010968)
RGD PMID:11010968 PMID:17878677 MGI:1929020 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3033512|PMID:14627707)
Ensembl
RGD
PMID:14627707 GO_REF:0000107 MGI:3033512 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Gdf3 growth differentiation factor 3 involved_in ISO (PMID:18823971) RGD PMID:18823971 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:15539560), (PMID:16816361), (PMID:27036124)
MGI:3046937 (MGI:3714585|PMID:17522159)
GO_REF:0000024
RGD
UniProt
PMID:15539560 PMID:16816361 PMID:17522159 PMID:27036124 GO_REF:0000024 MGI:3714585 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in ISO (MGI:5507937|PMID:23063586) RGD PMID:23063586 MGI:5507937 NCBI chr13:92,894,431...92,988,137
Ensembl chr13:92,894,431...92,988,137
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hjv hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88177 (MGI:4455113|PMID:20065295)
Ensembl
RGD
PMID:20065295 GO_REF:0000107 MGI:4455113 NCBI chr 2:198,655,437...198,659,318
Ensembl chr 2:198,655,437...198,659,317
JBrowse link
G Htra1 HtrA serine peptidase 1 acts_upstream_of_or_within ISO (MGI:3034116|PMID:14973287) RGD PMID:14973287 MGI:3034116 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3046453|PMID:15206957)
UniProt
RGD
PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:80,248,140...80,276,534
Ensembl chr14:80,248,140...80,276,534
JBrowse link
G Lemd2 LEM domain nuclear envelope protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,779,742...5,786,213
Ensembl chr20:6,545,083...6,556,350
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO
IBA
(PMID:15647271)
PMID:21873635
RGD PMID:15647271, PMID:21873635 RGD:13792537 NCBI chr 7:62,976,671...63,045,860
Ensembl chr 7:62,996,336...63,045,728
JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5908338|PMID:20460439)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20460439 GO_REF:0000024 GO_REF:0000107 MGI:5908338 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Mir675 microRNA 675 acts_upstream_of_or_within ISO (MGI:5566551|PMID:24532688) RGD PMID:24532688 MGI:5566551 NCBI chr 1:215,745,981...215,746,064
Ensembl chr 1:215,745,981...215,746,064
JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (MGI:3654744|PMID:16801560) RGD PMID:16801560 MGI:3654744 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5492288|PMID:23676271)
(PMID:23063586), (PMID:25561725)
UniProt
RGD
PMID:23063586 PMID:23676271 PMID:25561725 GO_REF:0000024 MGI:5492288 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:1862000|MGI:88177|MGI:88182 (MGI:3044331|PMID:15110716), (MGI:3590430|PMID:15975920), (MGI:3640733|PMID:16712836), (MGI:4397715|PMID:19852960), (MGI:4415813|PMID:18462699), (MGI:4429763|PMID:19850029)
(MGI:3703823|PMID:17360443), (MGI:3715084|PMID:17400546)
PMID:21873635
(PMID:10780858), (PMID:15539560), (PMID:8752214)
GO_REF:0000104
UniProt
RGD
PMID:8752214 PMID:10780858 PMID:15110716 PMID:15539560 PMID:15975920 PMID:16712836 PMID:17360443 PMID:17400546 PMID:18462699 PMID:19850029 PMID:19852960, PMID:21873635 GO_REF:0000024 GO_REF:0000104 MGI:3044331 MGI:3590430 MGI:3640733 MGI:3703823 MGI:3715084 MGI:4397715 MGI:4415813 MGI:4429763, RGD:13792537 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4412151|PMID:19695258) RGD PMID:19695258 MGI:4412151 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5613417|PMID:25100727)
Ensembl
RGD
PMID:25100727 GO_REF:0000107 MGI:5613417 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:108078 (MGI:4429763|PMID:19850029)
Ensembl
RGD
PMID:19850029 GO_REF:0000107 MGI:4429763 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:892014 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Ski SKI proto-oncogene involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:14699069), (PMID:17054724)
MGI:88177 (MGI:5300220|PMID:21937600)
PMID:21873635
RGD PMID:14699069 PMID:17054724 PMID:21937600, PMID:21873635 MGI:5300220, RGD:13792537 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Skil SKI-like proto-oncogene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Skor1 SKI family transcriptional corepressor 1 involved_in ISO
IBA
(PMID:17292623)
PMID:21873635
RGD PMID:17292623, PMID:21873635 RGD:13792537 NCBI chr 8:68,029,930...68,040,504
Ensembl chr 8:68,030,621...68,038,533
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88177 (MGI:5300220|PMID:21937600)
RGD PMID:21937600, PMID:21873635 MGI:5300220, RGD:13792537 NCBI chr18:73,145,596...73,199,395
Ensembl chr18:73,157,973...73,193,377
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001), (PMID:30848080), (PMID:9436979) RGD PMID:9436979 PMID:22275001 PMID:30848080 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smad7 SMAD family member 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4429763|PMID:19850029)
(PMID:17438144)
Ensembl
RGD
PMID:17438144 PMID:19850029 GO_REF:0000107 MGI:4429763 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IBA
ISO
PMID:21873635
(PMID:27214554)
RGD PMID:27214554, PMID:21873635 RGD:13792537 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:95,018,050...95,118,107
Ensembl chr10:95,018,059...95,062,987
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5704270|PMID:26584636) RGD PMID:26584636 MGI:5704270 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sost sclerostin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:14633986)
(MGI:3766170|PMID:17002572)
RGD PMID:14633986 PMID:17002572, PMID:21873635 MGI:3766170, RGD:13792537 NCBI chr10:89,897,087...89,900,131
Ensembl chr10:89,897,087...89,900,131
JBrowse link
G Sostdc1 sclerostin domain containing 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88180 (MGI:2681048|PMID:14623234), (MGI:3603904|PMID:16179481)
(PMID:15020244)
RGD PMID:14623234 PMID:15020244 PMID:16179481, PMID:21873635 MGI:2681048 MGI:3603904, RGD:13792537 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
G Spart spartin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5430946 (MGI:5430704|PMID:22619377)
RGD PMID:22619377, PMID:21873635 MGI:5430704, RGD:13792537 NCBI chr 2:144,522,382...144,548,968
Ensembl chr 2:144,522,072...144,548,917
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:3763872|PMID:17919533) RGD PMID:17919533 MGI:3763872 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tmprss6 transmembrane serine protease 6 acts_upstream_of_or_within ISO MGI:1321394|MGI:1916835|MGI:88177|MGI:88180 (MGI:5314735|PMID:19751239) RGD PMID:19751239 MGI:5314735 NCBI chr 7:119,659,323...119,689,953
Ensembl chr 7:119,659,324...119,689,938
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1928565|PMID:11163184)
Ensembl
RGD
PMID:11163184 GO_REF:0000107 MGI:1928565 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Trim33 tripartite motif-containing 33 involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr 2:205,783,252...205,863,426
Ensembl chr 2:205,783,252...205,858,433
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 acts_upstream_of_or_within ISO MGI:2655736 (MGI:2654977|PMID:12665593), (MGI:3577114|PMID:15780974) RGD PMID:12665593 PMID:15780974 MGI:2654977 MGI:3577114 NCBI chr 9:113,699,151...113,732,601
Ensembl chr 9:113,699,170...113,732,622
JBrowse link
G Vwc2 von Willebrand factor C domain containing 2 involved_in IBA
ISO
PMID:21873635
(MGI:3715084|PMID:17400546)
RGD PMID:17400546, PMID:21873635 MGI:3715084, RGD:13792537 NCBI chr14:91,201,141...91,348,219
Ensembl chr14:91,201,730...91,348,219
JBrowse link
G Vwc2l von Willebrand factor C domain containing 2 like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88177|MGI:88182 (MGI:4397715|PMID:19852960)
RGD PMID:19852960, PMID:21873635 MGI:4397715, RGD:13792537 NCBI chr 9:77,833,534...78,024,670
Ensembl chr 9:77,834,091...78,021,846
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16194878) RGD PMID:16194878 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857617 (MGI:3777488|PMID:18351662)
Ensembl
RGD
PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dact2 dishevelled-binding antagonist of beta-catenin 2 involved_in IBA
ISO
PMID:21873635
(MGI:3809364|PMID:18716284), (MGI:5437437|PMID:17197390)
RGD PMID:17197390 PMID:18716284, PMID:21873635 MGI:3809364 MGI:5437437, RGD:13792537 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
G Lefty1 left right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) RGD PMID:15062104 MGI:3042530 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
negative regulation of pathway-restricted SMAD protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Eng endoglin involved_in ISO (PMID:18974388) RGD PMID:18974388 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:24627487)
RGD PMID:24627487, PMID:21873635 RGD:13792537 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Nog noggin involved_in IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
(PMID:15539560)
Ensembl
RGD
PMID:15539560 PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in IBA
ISO
PMID:21873635
(MGI:5582164|PMID:20129061)
(PMID:20129061), (PMID:24627487)
RGD PMID:20129061 PMID:24627487, PMID:21873635 MGI:5582164, RGD:13792537 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9436979) RGD PMID:9436979 PMID:19047146 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:17438144)
GO_REF:0000107
RGD
Ensembl
PMID:17438144 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196) RGD PMID:21266196 NCBI chr16:49,328,958...49,432,415
Ensembl chr16:49,350,884...49,432,118
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
negative regulation of SMAD protein complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:24627487)
RGD PMID:24627487, PMID:21873635 RGD:13792537 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA
(PMID:20129061)
PMID:21873635
RGD PMID:20129061, PMID:21873635 RGD:13792537 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO (PMID:16751101) RGD PMID:16751101 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:9436979) RGD PMID:9436979 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within ISO (MGI:4943647|PMID:19661464) RGD PMID:19661464 MGI:4943647 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5504324|PMID:23653360)
UniProt
RGD
PMID:23653360 GO_REF:0000024 MGI:5504324 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO UniProtKB:P01137 (PMID:29167509) RGD PMID:29167509 NCBI chr 8:70,760,922...70,775,891
Ensembl chr 8:70,760,922...70,775,891
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588, PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:221,085,894...221,087,449
Ensembl chr 1:221,085,895...221,087,449
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO UniProtKB:Q9Y3F4 (PMID:23687415) RGD PMID:23687415 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated involved_in ISO MGI:5314628 (MGI:6163471|PMID:29563538) RGD PMID:29563538 MGI:6163471 NCBI chr17:77,252,099...77,262,301
Ensembl chr17:77,252,100...77,261,731
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:157,869,383...158,156,266
Ensembl chr 2:157,869,392...158,156,444
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:21170088)
GO_REF:0000107
RGD
Ensembl
PMID:21170088 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adamtsl2 ADAMTS-like 2 involved_in
acts_upstream_of_or_within
ISO (PMID:18677313)
(MGI:5638958|PMID:25762570)
RGD PMID:18677313 PMID:25762570 MGI:5638958 NCBI chr 3:5,624,473...5,654,890
Ensembl chr 3:5,624,506...5,654,910
JBrowse link
G Aspn asporin involved_in ISO (PMID:17827158)
(MGI:3762064|PMID:17827158)
RGD PMID:17827158 MGI:3762064 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:15,495,790...15,519,282
Ensembl chr17:15,495,790...15,519,282
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO (PMID:14660579), (PMID:19328798) RGD PMID:14660579 PMID:19328798 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bcl9l BCL9 like involved_in ISO
IBA
(PMID:19328798)
PMID:21873635
RGD PMID:19328798, PMID:21873635 RGD:13792537 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P01137 (PMID:28467929)
GO_REF:0000107
RGD
Ensembl
PMID:28467929 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Cav1 caveolin 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25893292)
UniProt
Ensembl
RGD
PMID:25893292 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98728 (MGI:5298182|PMID:21832243)
Ensembl
RGD
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Cd109 CD109 molecule involved_in ISO (PMID:16754747) RGD PMID:16754747 NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716
JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:3768618|PMID:17080483) RGD PMID:17080483 MGI:3768618 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO MGI:97359 (MGI:3055566|PMID:14721776) RGD PMID:14721776 MGI:3055566 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:25100282 RGD:9685289 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:85,515,610...85,517,516
Ensembl chr 1:85,516,653...85,517,360
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588, PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:221,085,894...221,087,449
Ensembl chr 1:221,085,895...221,087,449
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:42,983,879...43,088,074
Ensembl chr19:42,983,869...43,090,841
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 acts_upstream_of_or_within ISO MGI:98658 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htra1 HtrA serine peptidase 1 acts_upstream_of_or_within ISO (MGI:3034116|PMID:14973287) RGD PMID:14973287 MGI:3034116 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3046453|PMID:15206957)
UniProt
RGD
PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:80,248,140...80,276,534
Ensembl chr14:80,248,140...80,276,534
JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO
IBA
(PMID:24627487)
(MGI:5583005|PMID:24627487)
PMID:21873635
RGD PMID:24627487, PMID:21873635 MGI:5583005, RGD:13792537 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:62,976,671...63,045,860
Ensembl chr 7:62,996,336...63,045,728
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P01137 (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) RGD PMID:15897867 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Nepn nephrocan involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:33,527,932...33,543,860
Ensembl chr20:33,527,932...33,543,848
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19293183)
Ensembl
RGD
PMID:19293183 GO_REF:0000107 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1891408 (MGI:3588024|PMID:16103213)
Ensembl
RGD
PMID:16103213 GO_REF:0000107 MGI:3588024 NCBI chr 8:81,765,779...81,799,894
Ensembl chr 8:81,766,041...81,793,577
JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr18:59,830,375...59,882,490
Ensembl chr18:59,830,363...59,875,127
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:17327236) RGD PMID:17327236 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Peg10 paternally expressed 10 involved_in ISO (PMID:15611116) RGD PMID:15611116 NCBI chr 4:29,795,524...29,804,517 JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:19122240) RGD PMID:19122240 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA
(PMID:20129061), (PMID:24627487)
(MGI:5582164|PMID:20129061)
PMID:21873635
RGD PMID:20129061 PMID:24627487, PMID:21873635 MGI:5582164, RGD:13792537 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO (PMID:31611175) RGD PMID:31611175 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in
acts_upstream_of_or_within
ISO (PMID:31023188)
UniProtKB:P01137|UniProtKB:P12643 (PMID:28467929)
RGD PMID:28467929 PMID:31023188 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO (PMID:16751101) RGD PMID:16751101 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Prdm16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within
ISO (PMID:14656887)
MGI:3576024 (MGI:4430027|PMID:20007998)
(PMID:19049980)
RGD PMID:14656887 PMID:19049980 PMID:20007998 MGI:4430027 NCBI chr 5:171,662,277...171,711,561
Ensembl chr 5:171,662,277...171,710,316
JBrowse link
G Rasl11b RAS-like family 11 member B acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr14:36,550,353...36,554,574
Ensembl chr14:36,550,340...36,554,580
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306300|PMID:17098745) RGD PMID:17098745 MGI:5306300 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Ski SKI proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P01137 (PMID:15312649)
(PMID:17054724), (PMID:17469184), (PMID:19049980)
MGI:1201674 (MGI:5300220|PMID:21937600)
RGD PMID:15312649 PMID:17054724 PMID:17469184 PMID:19049980 PMID:21937600, PMID:21873635 MGI:5300220, RGD:13792537 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Skil SKI-like proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3530729|PMID:15677329)
(PMID:17469184), (PMID:19383336)
RGD PMID:15677329 PMID:17469184 PMID:19383336, PMID:21873635 MGI:3530729, RGD:13792537 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:16200078)
(MGI:5300220|PMID:21937600)
RGD PMID:16200078 PMID:21937600 MGI:5300220 NCBI chr18:73,145,596...73,199,395
Ensembl chr18:73,157,973...73,193,377
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171), (PMID:26376865) RGD PMID:16550171 PMID:26376865 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9256479) RGD PMID:9256479 PMID:19047146 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479)
GO_REF:0000107
RGD
Ensembl
PMID:9256479 PMID:12151385 PMID:17438144 PMID:18762808 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:11278251), (PMID:12151385) RGD PMID:11278251 PMID:12151385 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in ISO (PMID:19255252) RGD PMID:19255252 NCBI chr10:95,018,050...95,118,107
Ensembl chr10:95,018,059...95,062,987
JBrowse link
G Snx1 sorting nexin 1 acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr 8:71,745,687...71,786,182
Ensembl chr 8:71,745,896...71,784,551
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)
RGD PMID:21266196 MGI:5545984 NCBI chr16:49,328,958...49,432,415
Ensembl chr16:49,350,884...49,432,118
JBrowse link
G Snx6 sorting nexin 6 involved_in ISO (PMID:11279102) RGD PMID:11279102 NCBI chr 6:75,626,927...75,670,172
Ensembl chr 6:75,626,927...75,670,135
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414689|PMID:25576668)
UniProt
RGD
PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Strap serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
ISO (PMID:23687415)
(MGI:1321347|PMID:9856985)
RGD PMID:9856985 PMID:23687415 MGI:1321347 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO MGI:95835 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 8:119,215,266...119,220,909
Ensembl chr 8:119,215,495...119,219,232
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:12071374 RGD:730235 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:10746731 RGD:1579946 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3528807|PMID:15657445) RGD PMID:15657445 MGI:3528807 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Vasn vasorin involved_in IBA
ISO
PMID:21873635
(PMID:15247411), (PMID:21170088)
RGD PMID:15247411 PMID:21170088, PMID:21873635 RGD:13792537 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:157,869,383...158,156,266
Ensembl chr 2:157,869,392...158,156,444
JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789, PMID:21873635 RGD:13792537 NCBI chr10:15,243,429...15,245,757
Ensembl chr10:15,243,429...15,245,757
JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789, PMID:21873635 RGD:13792537 NCBI chr10:81,936,156...81,943,142
Ensembl chr10:81,936,444...81,942,188
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25514493)
UniProt
Ensembl
RGD
PMID:25514493 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:11,429,266...11,446,119
Ensembl chr 7:11,432,049...11,444,786
JBrowse link
G Zfp451 zinc finger protein 451 involved_in ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:38,395,464...38,451,585
Ensembl chr 9:38,396,449...38,451,656
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
ISO
PMID:21873635
(MGI:5507937|PMID:23063586)
RGD PMID:23063586, PMID:21873635 MGI:5507937, RGD:13792537 NCBI chr13:92,894,431...92,988,137
Ensembl chr13:92,894,431...92,988,137
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO
IEA
IBA
(PMID:23063586)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:23063586, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:9660951)
(MGI:1858315|PMID:10748465)
PMID:21873635
RGD PMID:9660951 PMID:10748465, PMID:21873635 MGI:1858315, RGD:13792537 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IEA
ISO
GO_REF:0000107
(MGI:1203284|PMID:9660951)
Ensembl
RGD
PMID:9660951 GO_REF:0000107 MGI:1203284 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
(PMID:2022183), (PMID:8617200)
GO_REF:0000024
RGD
UniProt
PMID:2022183 PMID:8617200 GO_REF:0000024 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr11:71,872,728...71,889,897
Ensembl chr11:71,872,830...71,889,887
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    negative regulation of biological process 5621
      negative regulation of signaling 1406
        negative regulation of signal transduction 1265
          negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 131
            negative regulation of BMP signaling pathway + 56
            negative regulation of SMAD protein complex assembly 5
            negative regulation of SMAD protein signal transduction 9
            negative regulation of activin receptor signaling pathway + 13
            negative regulation of pathway-restricted SMAD protein phosphorylation 13
            negative regulation of transforming growth factor beta receptor signaling pathway + 79
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              enzyme linked receptor protein signaling pathway 978
                transmembrane receptor protein serine/threonine kinase signaling pathway 391
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 259
                    negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 131
                      negative regulation of BMP signaling pathway + 56
                      negative regulation of SMAD protein complex assembly 5
                      negative regulation of SMAD protein signal transduction 9
                      negative regulation of activin receptor signaling pathway + 13
                      negative regulation of pathway-restricted SMAD protein phosphorylation 13
                      negative regulation of transforming growth factor beta receptor signaling pathway + 79
paths to the root