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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
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Accession:GO:0090101 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms:exact_synonym: negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway



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negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fstl3 follistatin like 3 involved_in ISO (PMID:17878677) RGD PMID:17878677 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:9884026) RGD PMID:9884026 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:9660951)
(MGI:1858315|PMID:10748465)
RGD PMID:9660951 PMID:10748465 MGI:1858315 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Fst follistatin involved_in IBA
ISO
PMID:21873635
(PMID:11948405), (PMID:12697670), (PMID:12702211)
RGD PMID:11948405 PMID:12697670 PMID:12702211 PMID:21873635 RGD:13792537 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fstl3 follistatin like 3 involved_in ISO
IBA
(PMID:11948405), (PMID:12697670)
PMID:21873635
RGD PMID:11948405 PMID:12697670 PMID:21873635 RGD:13792537 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 involved_in ISO (PMID:11266516) RGD PMID:11266516 NCBI chr  X:129,069,891...129,085,331
Ensembl chr  X:129,069,896...129,085,139
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1353670|PMID:10681527)
UniProt
RGD
PMID:10681527 GO_REF:0000024 MGI:1353670 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Mir210 microRNA 210 acts_upstream_of_or_within ISO (MGI:3851892|PMID:19520079) RGD PMID:19520079 MGI:3851892 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Ski Ski proto-oncogene involved_in ISO (PMID:14699069) RGD PMID:14699069 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bmper BMP-binding endothelial regulator acts_upstream_of_or_within ISO (MGI:2670247|PMID:12897139) RGD PMID:12897139 MGI:2670247 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:15657086) RGD PMID:15657086 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist acts_upstream_of_or_within ISO (MGI:1101446|PMID:9431803), (MGI:1197794|PMID:9501024) RGD PMID:9431803 PMID:9501024 MGI:1101446 MGI:1197794 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Chrd chordin involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:3525426|PMID:15381701)
(MGI:3577114|PMID:15780974), (MGI:4429763|PMID:19850029)
(PMID:11472837)
Ensembl
RGD
PMID:11472837 PMID:15381701 PMID:15780974 PMID:19850029 PMID:21873635 GO_REF:0000107 MGI:3525426 MGI:3577114 MGI:4429763, RGD:13792537 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
JBrowse link
G Chrdl1 chordin-like 1 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:1934402|PMID:11401399)
(MGI:5492288|PMID:23676271)
Ensembl
RGD
PMID:11401399 PMID:23676271 PMID:21873635 GO_REF:0000107 MGI:1934402 MGI:5492288, RGD:13792537 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921
JBrowse link
G Chrdl2 chordin-like 2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2683044|PMID:14660436)
PMID:21873635
RGD PMID:14660436 PMID:21873635 MGI:2683044, RGD:13792537 NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:154,343,201...154,370,640
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
JBrowse link
G Ctdspl2 CTD small phosphatase like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5613417|PMID:25100727)
Ensembl
RGD
PMID:25100727 GO_REF:0000107 MGI:5613417 NCBI chr 3:108,914,650...108,970,620
Ensembl chr 3:108,915,280...108,967,227
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlx1 distal-less homeobox 1 involved_in ISO
ISS
IEA
(PMID:14671321)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:14671321 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
JBrowse link
G Fstl3 follistatin like 3 involved_in
acts_upstream_of_or_within
ISO (PMID:17878677)
(MGI:1929020|PMID:11010968)
RGD PMID:11010968 PMID:17878677 MGI:1929020 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within ISO (MGI:3033512|PMID:14627707) RGD PMID:14627707 MGI:3033512 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Gdf3 growth differentiation factor 3 involved_in ISO (PMID:18823971) RGD PMID:18823971 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:15539560), (PMID:16816361), (PMID:27036124)
MGI:3046937 (MGI:3714585|PMID:17522159)
GO_REF:0000024
RGD
UniProt
PMID:15539560 PMID:16816361 PMID:17522159 PMID:27036124 GO_REF:0000024 MGI:3714585 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in ISO (MGI:5507937|PMID:23063586) RGD PMID:23063586 MGI:5507937 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hjv hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88177 (MGI:4455113|PMID:20065295)
Ensembl
RGD
PMID:20065295 GO_REF:0000107 MGI:4455113 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Htra1 HtrA serine peptidase 1 acts_upstream_of_or_within ISO (MGI:3034116|PMID:14973287) RGD PMID:14973287 MGI:3034116 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3046453|PMID:15206957)
UniProt
RGD
PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO
IBA
(PMID:15647271)
PMID:21873635
RGD PMID:15647271 PMID:21873635 RGD:13792537 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474
JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5908338|PMID:20460439)
UniProt
RGD
PMID:20460439 GO_REF:0000024 MGI:5908338 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Mir100 microRNA 100 acts_upstream_of ISO (PMID:22684006) RGD PMID:22684006 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
JBrowse link
G Mir106a microRNA 106a acts_upstream_of ISO (PMID:23399447) RGD PMID:23399447 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661
JBrowse link
G Mir125b1 microRNA 125b-1 acts_upstream_of ISO (PMID:28214897) RGD PMID:28214897 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir125b2 microRNA 125b-2 acts_upstream_of ISO (PMID:28214897) RGD PMID:28214897 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir140 microRNA 140 acts_upstream_of ISO (PMID:24928442) RGD PMID:24928442 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir17 microRNA 17 acts_upstream_of ISO (PMID:23399447) RGD PMID:23399447 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir20a microRNA 20a involved_in ISO UniProtKB:P12643 (PMID:22450430) RGD PMID:22450430 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir210 microRNA 210 acts_upstream_of ISO (PMID:29944867) RGD PMID:29944867 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir214 microRNA 214 acts_upstream_of ISO (PMID:30703347) RGD PMID:30703347 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:24047927) RGD PMID:24047927 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
JBrowse link
G Mir675 microRNA 675 acts_upstream_of_or_within ISO (MGI:5566551|PMID:24532688) RGD PMID:24532688 MGI:5566551 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358
JBrowse link
G Mir93 microRNA 93 acts_upstream_of ISO (PMID:28797104) RGD PMID:28797104 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:27860183) RGD PMID:27860183 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (MGI:3654744|PMID:16801560) RGD PMID:16801560 MGI:3654744 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5492288|PMID:23676271)
(PMID:23063586), (PMID:25561725)
UniProt
RGD
PMID:23063586 PMID:23676271 PMID:25561725 GO_REF:0000024 MGI:5492288 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:1862000|MGI:88177|MGI:88182 (MGI:3044331|PMID:15110716), (MGI:3590430|PMID:15975920), (MGI:3640733|PMID:16712836), (MGI:4397715|PMID:19852960), (MGI:4415813|PMID:18462699), (MGI:4429763|PMID:19850029)
(MGI:3703823|PMID:17360443), (MGI:3715084|PMID:17400546)
PMID:21873635
(PMID:10780858), (PMID:15539560), (PMID:8752214)
GO_REF:0000104
UniProt
RGD
PMID:8752214 PMID:10780858 PMID:15110716 PMID:15539560 PMID:15975920 More... GO_REF:0000024 GO_REF:0000104 MGI:3044331 MGI:3590430 MGI:3640733 MGI:3703823 MGI:3715084 MGI:4397715 MGI:4415813 MGI:4429763, RGD:13792537 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4412151|PMID:19695258) RGD PMID:19695258 MGI:4412151 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of_or_within ISO (PMID:21743293) RGD PMID:21743293 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5613417|PMID:25100727)
Ensembl
RGD
PMID:25100727 GO_REF:0000107 MGI:5613417 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:108078 (MGI:4429763|PMID:19850029)
Ensembl
RGD
PMID:19850029 GO_REF:0000107 MGI:4429763 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:892014 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Ski Ski proto-oncogene involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:14699069), (PMID:17054724)
MGI:88177 (MGI:5300220|PMID:21937600)
PMID:21873635
RGD PMID:14699069 PMID:17054724 PMID:21937600 PMID:21873635 MGI:5300220, RGD:13792537 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Skil SKI-like proto-oncogene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Skor1 SKI family transcriptional corepressor 1 involved_in ISO
IBA
(PMID:17292623)
PMID:21873635
RGD PMID:17292623 PMID:21873635 RGD:13792537 NCBI chr 8:63,599,153...63,609,727
Ensembl chr 8:63,599,165...63,607,756
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88177 (MGI:5300220|PMID:21937600)
RGD PMID:21937600 PMID:21873635 MGI:5300220, RGD:13792537 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001), (PMID:30848080), (PMID:9436979) RGD PMID:9436979 PMID:22275001 PMID:30848080 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4429763|PMID:19850029)
(PMID:17438144)
Ensembl
RGD
PMID:17438144 PMID:19850029 GO_REF:0000107 MGI:4429763 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IBA
ISO
PMID:21873635
(PMID:27214554)
RGD PMID:27214554 PMID:21873635 RGD:13792537 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5704270|PMID:26584636) RGD PMID:26584636 MGI:5704270 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Sost sclerostin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:14633986)
(MGI:3766170|PMID:17002572)
RGD PMID:14633986 PMID:17002572 PMID:21873635 MGI:3766170, RGD:13792537 NCBI chr10:86,912,517...86,915,561
Ensembl chr10:86,911,517...86,915,561
JBrowse link
G Sostdc1 sclerostin domain containing 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88180 (MGI:2681048|PMID:14623234), (MGI:3603904|PMID:16179481)
(PMID:15020244)
RGD PMID:14623234 PMID:15020244 PMID:16179481 PMID:21873635 MGI:2681048 MGI:3603904, RGD:13792537 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
G Spart spartin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5430946 (MGI:5430704|PMID:22619377)
RGD PMID:22619377 PMID:21873635 MGI:5430704, RGD:13792537 NCBI chr 2:139,292,630...139,319,248
Ensembl chr 2:139,292,355...139,319,248
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:3763872|PMID:17919533) RGD PMID:17919533 MGI:3763872 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tmem53 transmembrane protein 53 involved_in ISO
IEA
(PMID:33824347)
(MGI:6713651|PMID:33824347)
GO_REF:0000107
RGD
Ensembl
PMID:33824347 GO_REF:0000107 MGI:6713651 NCBI chr 5:130,721,780...130,737,692
Ensembl chr 5:130,721,659...130,737,692
JBrowse link
G Tmprss6 transmembrane serine protease 6 acts_upstream_of_or_within ISO MGI:1321394|MGI:1916835|MGI:88177|MGI:88180 (MGI:5314735|PMID:19751239) RGD PMID:19751239 MGI:5314735 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO (PMID:16771708) RGD PMID:16771708 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1928565|PMID:11163184)
Ensembl
RGD
PMID:11163184 GO_REF:0000107 MGI:1928565 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Trim33 tripartite motif-containing 33 involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 acts_upstream_of_or_within ISO MGI:2655736 (MGI:2654977|PMID:12665593), (MGI:3577114|PMID:15780974) RGD PMID:12665593 PMID:15780974 MGI:2654977 MGI:3577114 NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479
JBrowse link
G Vwc2 von Willebrand factor C domain containing 2 involved_in IBA
ISO
PMID:21873635
(MGI:3715084|PMID:17400546)
RGD PMID:17400546 PMID:21873635 MGI:3715084, RGD:13792537 NCBI chr14:85,683,670...85,825,068
Ensembl chr14:85,684,414...85,818,524
JBrowse link
G Vwc2l von Willebrand factor C domain containing 2 like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88177|MGI:88182 (MGI:4397715|PMID:19852960)
RGD PMID:19852960 PMID:21873635 MGI:4397715, RGD:13792537 NCBI chr 9:72,252,793...72,448,543
Ensembl chr 9:72,253,387...72,444,839
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16194878) RGD PMID:16194878 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:3777488|PMID:18351662) RGD PMID:18351662 MGI:3777488 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dact2 dishevelled-binding antagonist of beta-catenin 2 involved_in IBA
ISO
PMID:21873635
(MGI:3809364|PMID:18716284), (MGI:5437437|PMID:17197390)
RGD PMID:17197390 PMID:18716284 PMID:21873635 MGI:3809364 MGI:5437437, RGD:13792537 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Lefty1 left right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) RGD PMID:15062104 MGI:3042530 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
negative regulation of pathway-restricted SMAD protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Eng endoglin involved_in ISO (PMID:18974388) RGD PMID:18974388 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:24627487)
RGD PMID:24627487 PMID:21873635 RGD:13792537 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mirlet7g microRNA let-7g involved_in ISO (PMID:24291274) RGD PMID:24291274 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
JBrowse link
G Nog noggin involved_in IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
(PMID:15539560)
Ensembl
RGD
PMID:15539560 PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in IBA
ISO
PMID:21873635
(MGI:5582164|PMID:20129061)
(PMID:20129061), (PMID:24627487)
RGD PMID:20129061 PMID:24627487 PMID:21873635 MGI:5582164, RGD:13792537 NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9436979) RGD PMID:9436979 PMID:19047146 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:17438144)
GO_REF:0000107
RGD
Ensembl
PMID:17438144 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196) RGD PMID:21266196 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
negative regulation of SMAD protein complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:24627487)
RGD PMID:24627487 PMID:21873635 RGD:13792537 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA
(PMID:20129061)
PMID:21873635
RGD PMID:20129061 PMID:21873635 RGD:13792537 NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA
(PMID:16751101)
GO_REF:0000107
RGD
Ensembl
PMID:16751101 GO_REF:0000107 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:9436979) RGD PMID:9436979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within ISO (MGI:4943647|PMID:19661464) RGD PMID:19661464 MGI:4943647 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5504324|PMID:23653360)
UniProt
RGD
PMID:23653360 GO_REF:0000024 MGI:5504324 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO UniProtKB:P01137 (PMID:29167509) RGD PMID:29167509 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588 PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mir130a microRNA 130a acts_upstream_of ISO (PMID:30741461) RGD PMID:30741461 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir140 microRNA 140 acts_upstream_of ISO UniProtKB:P12643 (PMID:24928442) RGD PMID:24928442 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:30779466) RGD PMID:30779466 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir205 microRNA 205 acts_upstream_of ISO UniProtKB:Q15797 (PMID:23800974), (PMID:25012146) RGD PMID:23800974 PMID:25012146 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir23a microRNA 23a acts_upstream_of ISO (PMID:26400397) RGD PMID:26400397 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
JBrowse link
G Mir27a microRNA 27a acts_upstream_of ISO (PMID:26400397) RGD PMID:26400397 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO UniProtKB:Q9Y3F4 (PMID:23687415) RGD PMID:23687415 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated involved_in ISO MGI:5314628 (MGI:6163471|PMID:29563538) RGD PMID:29563538 MGI:6163471 NCBI chr17:73,293,977...73,303,728
Ensembl chr17:73,293,978...73,303,611
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:21170088) RGD PMID:21170088 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamtsl2 ADAMTS-like 2 involved_in
acts_upstream_of_or_within
ISO (PMID:18677313)
(MGI:5638958|PMID:25762570)
RGD PMID:18677313 PMID:25762570 MGI:5638958 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554
JBrowse link
G Aspn asporin involved_in ISO (PMID:17827158)
(MGI:3762064|PMID:17827158)
RGD PMID:17827158 MGI:3762064 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO
IEA
(PMID:14660579), (PMID:19328798)
GO_REF:0000002
RGD
InterPro
PMID:14660579 PMID:19328798 GO_REF:0000002 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bcl9l BCL9 like involved_in ISO
IBA
(PMID:19328798)
PMID:21873635
RGD PMID:19328798 PMID:21873635 RGD:13792537 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P01137 (PMID:28467929)
GO_REF:0000107
RGD
Ensembl
PMID:28467929 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Brms1l BRMS1 like transcriptional repressor involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 6:73,266,673...73,300,631
Ensembl chr 6:73,266,691...73,300,631
JBrowse link
G Cav1 caveolin 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 GO_REF:0000024 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98728 (MGI:5298182|PMID:21832243)
Ensembl
RGD
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cd109 CD109 molecule involved_in ISO (PMID:16754747) RGD PMID:16754747 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:3768618|PMID:17080483) RGD PMID:17080483 MGI:3768618 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cilp cartilage intermediate layer protein involved_in IEA
ISO
GO_REF:0000107
(PMID:29167509)
Ensembl
RGD
PMID:29167509 GO_REF:0000107 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO MGI:97359 (MGI:3055566|PMID:14721776) RGD PMID:14721776 MGI:3055566 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:25100282 RGD:9685289 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,217...83,542,262 JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588 PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) RGD PMID:24613385
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 acts_upstream_of_or_within ISO MGI:98658 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra1 HtrA serine peptidase 1 acts_upstream_of_or_within ISO (MGI:3034116|PMID:14973287) RGD PMID:14973287 MGI:3034116 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3046453|PMID:15206957)
UniProt
RGD
PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315
JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO
IBA
(PMID:24627487)
(MGI:5583005|PMID:24627487)
PMID:21873635
RGD PMID:24627487 PMID:21873635 MGI:5583005, RGD:13792537 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P01137 (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) RGD PMID:15897867 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mir342 microRNA 342 involved_in ISO (PMID:26857067) RGD PMID:26857067 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226
JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714
JBrowse link
G Mirlet7g microRNA let-7g involved_in ISO (PMID:24291274) RGD PMID:24291274 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in ISO
IEA
(PMID:19293183)
GO_REF:0000107
RGD
Ensembl
PMID:19293183 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:1891408 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr18:57,831,647...57,881,287
Ensembl chr18:57,832,111...57,879,629
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:17327236) RGD PMID:17327236 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Peg10 paternally expressed 10 involved_in ISO (PMID:15611116) RGD PMID:15611116 NCBI chr 4:32,842,394...32,855,641
Ensembl chr 4:32,848,493...32,852,621
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:19122240) RGD PMID:19122240 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA
(PMID:20129061), (PMID:24627487)
(MGI:5582164|PMID:20129061)
PMID:21873635
RGD PMID:20129061 PMID:24627487 PMID:21873635 MGI:5582164, RGD:13792537 NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO (PMID:31611175) RGD PMID:31611175 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in
acts_upstream_of_or_within
ISO (PMID:31023188)
UniProtKB:P01137|UniProtKB:P12643 (PMID:28467929)
RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA
(PMID:16751101)
GO_REF:0000107
RGD
Ensembl
PMID:16751101 GO_REF:0000107 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Prdm16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within
ISO (PMID:14656887)
MGI:3576024 (MGI:4430027|PMID:20007998)
(PMID:19049980)
RGD PMID:14656887 PMID:19049980 PMID:20007998 MGI:4430027 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Rasl11b RAS-like family 11 member B acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306300|PMID:17098745) RGD PMID:17098745 MGI:5306300 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Ski Ski proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P01137 (PMID:15312649)
(PMID:17054724), (PMID:17469184), (PMID:19049980)
MGI:1201674 (MGI:5300220|PMID:21937600)
RGD PMID:15312649 PMID:17054724 PMID:17469184 PMID:19049980 PMID:21937600 More... MGI:5300220, RGD:13792537 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Skil SKI-like proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3530729|PMID:15677329)
(PMID:17469184), (PMID:19383336)
RGD PMID:15677329 PMID:17469184 PMID:19383336 PMID:21873635 MGI:3530729, RGD:13792537 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:16200078)
(MGI:5300220|PMID:21937600)
RGD PMID:16200078 PMID:21937600 MGI:5300220 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171), (PMID:26376865) RGD PMID:16550171 PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9256479) RGD PMID:9256479 PMID:19047146 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479)
GO_REF:0000107
RGD
Ensembl
PMID:9256479 PMID:12151385 PMID:17438144 PMID:18762808 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:11278251), (PMID:12151385) RGD PMID:11278251 PMID:12151385 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in ISO (PMID:19255252) RGD PMID:19255252 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Snx1 sorting nexin 1 acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)
RGD PMID:21266196 MGI:5545984 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440
JBrowse link
G Snx6 sorting nexin 6 involved_in ISO (PMID:11279102) RGD PMID:11279102 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414689|PMID:25576668)
UniProt
RGD
PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Strap serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
ISO (PMID:23687415)
(MGI:1321347|PMID:9856985)
RGD PMID:9856985 PMID:23687415 MGI:1321347 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Suds3 SDS3 homolog, SIN3A corepressor complex component involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr12:39,477,181...39,499,633
Ensembl chr12:39,477,568...39,499,628
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO MGI:95835 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:12071374 RGD:730235 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:10746731 RGD:1579946 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3528807|PMID:15657445) RGD PMID:15657445 MGI:3528807 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Vasn vasorin involved_in IBA
ISO
PMID:21873635
(PMID:15247411), (PMID:21170088)
RGD PMID:15247411 PMID:21170088 PMID:21873635 RGD:13792537 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789 PMID:21873635 RGD:13792537 NCBI chr10:14,896,442...14,898,770
Ensembl chr10:14,896,378...14,899,863
JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789 PMID:21873635 RGD:13792537 NCBI chr10:79,185,563...79,192,719
Ensembl chr10:79,186,647...79,191,657
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25514493)
UniProt
Ensembl
RGD
PMID:25514493 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539
JBrowse link
G Zfp451 zinc finger protein 451 involved_in ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
ISO
PMID:21873635
(MGI:5507937|PMID:23063586)
RGD PMID:23063586 PMID:21873635 MGI:5507937, RGD:13792537 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:23063586)
PMID:21873635
RGD PMID:23063586 PMID:21873635 RGD:13792537 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:9660951)
(MGI:1858315|PMID:10748465)
PMID:21873635
RGD PMID:9660951 PMID:10748465 PMID:21873635 MGI:1858315, RGD:13792537 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO (MGI:1203284|PMID:9660951) RGD PMID:9660951 MGI:1203284 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
(PMID:2022183), (PMID:8617200)
GO_REF:0000024
RGD
UniProt
PMID:2022183 PMID:8617200 GO_REF:0000024 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    negative regulation of biological process 5871
      negative regulation of signaling 1516
        negative regulation of signal transduction 1366
          negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 157
            negative regulation of BMP signaling pathway + 69
            negative regulation of SMAD protein complex assembly 5
            negative regulation of SMAD protein signal transduction 15
            negative regulation of activin receptor signaling pathway + 13
            negative regulation of pathway-restricted SMAD protein phosphorylation 14
            negative regulation of transforming growth factor beta receptor signaling pathway + 91
Path 2
Term Annotations click to browse term
  biological_process 20091
    biological regulation 13996
      regulation of biological process 13218
        regulation of cellular process 12482
          signal transduction 7133
            cell surface receptor signaling pathway 2860
              enzyme-linked receptor protein signaling pathway 1048
                transmembrane receptor protein serine/threonine kinase signaling pathway 423
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 289
                    negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 157
                      negative regulation of BMP signaling pathway + 69
                      negative regulation of SMAD protein complex assembly 5
                      negative regulation of SMAD protein signal transduction 15
                      negative regulation of activin receptor signaling pathway + 13
                      negative regulation of pathway-restricted SMAD protein phosphorylation 14
                      negative regulation of transforming growth factor beta receptor signaling pathway + 91
paths to the root