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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
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Accession:GO:0090100 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms:exact_synonym: positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway



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positive regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B involved_in ISO (PMID:16720724) RGD PMID:16720724 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Acvr2a activin A receptor type 2A involved_in IEA
ISO
GO_REF:0000107
(PMID:12665502)
Ensembl
RGD
PMID:12665502 GO_REF:0000107 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:8622651) RGD PMID:8622651 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO
IEA
(PMID:19592636)
GO_REF:0000107
RGD
Ensembl
PMID:19592636 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO (MGI:5444317|PMID:23034635) RGD PMID:23034635 MGI:5444317 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO UniProtKB:Q8NER5 (PMID:15150278) RGD PMID:15150278 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
G Zc3h3 zinc finger CCCH type containing 3 acts_upstream_of_or_within ISO MGI:1338944 (MGI:3619747|PMID:16115198) RGD PMID:16115198 MGI:3619747 NCBI chr 7:107,440,694...107,525,451
Ensembl chr 7:107,440,694...107,525,451
JBrowse link
positive regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:17068149)
(MGI:4830635|PMID:20406889)
RGD PMID:17068149 PMID:20406889 MGI:4830635 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:4418577|PMID:20059955)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20059955 GO_REF:0000024 GO_REF:0000107 MGI:4418577 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:17992660) RGD PMID:17992660 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO UniProtKB:P21274 (PMID:20675382) RGD PMID:20675382 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5296388|PMID:22072575)
UniProt
RGD
PMID:22072575 GO_REF:0000024 MGI:5296388 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
JBrowse link
G Elapor2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 involved_in IBA
ISO
PMID:21873635
(MGI:6393099|PMID:21177533)
RGD PMID:21177533 PMID:21873635 MGI:6393099, RGD:13792537 NCBI chr 4:24,613,163...24,805,729
Ensembl chr 4:24,613,163...24,805,729
JBrowse link
G Eng endoglin involved_in ISO (PMID:17068149) RGD PMID:17068149 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Fbxl15 F-box and leucine-rich repeat protein 15 involved_in ISO
ISS
(PMID:21572392)
GO_REF:0000024
RGD
UniProt
PMID:21572392 GO_REF:0000024 NCBI chr 1:245,189,732...245,191,973
Ensembl chr 1:245,189,736...245,192,007
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO MGI:3042750 (MGI:3806189|PMID:18590716) RGD PMID:18590716 MGI:3806189 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
JBrowse link
G Foxd1 forkhead box D1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3525902|PMID:15634693)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15634693 GO_REF:0000024 GO_REF:0000107 MGI:3525902 NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978
JBrowse link
G Gata4 GATA binding protein 4 involved_in IDA PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gata6 GATA binding protein 6 involved_in IDA PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273), (PMID:24098149) RGD PMID:21976273 PMID:24098149 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159356 (MGI:3583399|PMID:15925496)
Ensembl
RGD
PMID:15925496 GO_REF:0000107 MGI:3583399 NCBI chr  X:131,868,983...132,236,837
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104876 (MGI:3807421|PMID:18579678)
Ensembl
RGD
PMID:18579678 GO_REF:0000107 MGI:3807421 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:104853 (MGI:3807421|PMID:18579678)
UniProt
RGD
PMID:18579678 GO_REF:0000024 MGI:3807421 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Ilk integrin-linked kinase involved_in ISO (MGI:5009350|PMID:20675382) RGD PMID:20675382 MGI:5009350 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Kcp kielin cysteine rich BMP regulator acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3575605|PMID:15793581)
PMID:21873635
RGD PMID:15793581 PMID:21873635 MGI:3575605, RGD:13792537 NCBI chr 4:58,082,856...58,118,170
Ensembl chr 4:58,082,857...58,109,768
JBrowse link
G Kdr kinase insert domain receptor involved_in ISO
IEA
(MGI:4830635|PMID:20406889)
GO_REF:0000107
RGD
Ensembl
PMID:20406889 GO_REF:0000107 MGI:4830635 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Mir140 microRNA 140 involved_in ISO (PMID:27214554) RGD PMID:27214554 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21743293) RGD PMID:21743293 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:97169 (MGI:3810851|PMID:18667074) RGD PMID:18667074 MGI:3810851 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97168 (MGI:3810851|PMID:18667074)
Ensembl
RGD
PMID:18667074 GO_REF:0000107 MGI:3810851 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO MGI:88177 (MGI:4455113|PMID:20065295) RGD PMID:20065295 MGI:4455113 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4844232|PMID:20547764)
UniProt
RGD
PMID:20547764 GO_REF:0000024 MGI:4844232 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch2 notch receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3617328 (MGI:5492288|PMID:23676271)
Ensembl
RGD
PMID:23676271 GO_REF:0000107 MGI:5492288 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 involved_in ISO (MGI:5754878|PMID:26765568) RGD PMID:26765568 MGI:5754878 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO MGI:2450933 (MGI:5705244|PMID:24835669) RGD PMID:24835669 MGI:5705244 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:3701380 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rnf165 ring finger protein 165 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5516581 (MGI:5499270|PMID:23610558)
RGD PMID:23610558 PMID:21873635 MGI:5499270, RGD:13792537 NCBI chr18:70,984,566...71,100,836
Ensembl chr18:70,989,731...71,100,836
JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 involved_in ISO (PMID:33308444) RGD PMID:33308444 NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584
JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad4 SMAD family member 4 involved_in ISO
IEA
(PMID:19366699)
GO_REF:0000107
RGD
Ensembl
PMID:19366699 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:3797299|PMID:18423449)
UniProt
RGD
PMID:18423449 GO_REF:0000024 MGI:3797299 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Sulf1 sulfatase 1 involved_in ISO
IEA
ISS
(PMID:20479257)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20479257 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of ISO (MGI:5299248|PMID:21983003) RGD PMID:21983003 MGI:5299248 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:5617089|PMID:25382630) RGD PMID:25382630 MGI:5617089 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 acts_upstream_of_or_within ISO MGI:2655736 (MGI:2654977|PMID:12665593) RGD PMID:12665593 MGI:2654977 NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479
JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O involved_in ISO (PMID:23455153) RGD PMID:23455153 NCBI chr10:101,765,572...101,812,736
Ensembl chr10:101,766,005...101,812,899
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO MGI:1338938 (MGI:5468994|PMID:20042595) RGD PMID:20042595 MGI:5468994 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
G Zfp423 zinc finger protein 423 involved_in ISS
ISO
GO_REF:0000024
(MGI:4844232|PMID:20547764)
UniProt
RGD
PMID:20547764 GO_REF:0000024 MGI:4844232 NCBI chr19:19,111,538...19,407,371
Ensembl chr19:19,110,238...19,407,373
JBrowse link
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad2 SMAD family member 2 involved_in ISO (PMID:17239842) RGD PMID:17239842 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Zic2 Zic family member 2 acts_upstream_of_or_within ISO MGI:1862004 (MGI:5584215|PMID:24585447) RGD PMID:24585447 MGI:5584215 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522
JBrowse link
positive regulation of pathway-restricted SMAD protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:19506109)
(MGI:3610266|PMID:16140292)
RGD PMID:16140292 PMID:19506109 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Acvr1b activin A receptor type 1B IMP RGD PMID:17040568 RGD:2315948 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Acvr2a activin A receptor type 2A involved_in IEA
ISO
GO_REF:0000107
(PMID:19366699)
Ensembl
RGD
PMID:19366699 GO_REF:0000107 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:3695247|PMID:16798733)
(PMID:16049014), (PMID:17068149), (PMID:19903896)
Ensembl
RGD
PMID:16049014 PMID:16798733 PMID:17068149 PMID:19903896 PMID:21873635 GO_REF:0000107 MGI:3695247, RGD:13792537 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Bmp15 bone morphogenetic protein 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IBA
ISS
(PMID:16049014), (PMID:17244894), (PMID:17992660), (PMID:19664780)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:16049014 PMID:17244894 PMID:17992660 PMID:19664780 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp3 bone morphogenetic protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:16816361), (PMID:17244894), (PMID:17992660), (PMID:20559569), (PMID:9389648)
Ensembl
UniProt
RGD
PMID:9389648 PMID:16816361 PMID:17244894 PMID:17992660 PMID:20559569 More... GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO
IBA
(PMID:11580864)
PMID:21873635
RGD PMID:11580864 PMID:21873635 RGD:13792537 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IBA
ISS
(PMID:17244894), (PMID:19366699)
PMID:21873635
(MGI:4352622|PMID:19252488)
GO_REF:0000024
RGD
UniProt
PMID:17244894 PMID:19252488 PMID:19366699 PMID:21873635 GO_REF:0000024 MGI:4352622, RGD:13792537 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO
IBA
(PMID:16049014), (PMID:17244894), (PMID:19736306), (PMID:9311995)
PMID:21873635
RGD PMID:9311995 PMID:16049014 PMID:17244894 PMID:19736306 PMID:21873635 RGD:13792537 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bmp8a bone morphogenetic protein 8a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
JBrowse link
G Bmp8b bone morphogenetic protein 8b involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:135,386,058...135,411,337
Ensembl chr 5:135,386,311...135,405,197
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:24904118), (PMID:9389648) RGD PMID:9389648 PMID:24904118 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:17992660), (PMID:19366699) RGD PMID:17992660 PMID:19366699 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO
IEA
(PMID:19592636)
GO_REF:0000107
RGD
Ensembl
PMID:19592636 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11387212)
(MGI:5317100|PMID:20881059)
Ensembl
RGD
PMID:11387212 PMID:20881059 GO_REF:0000107 MGI:5317100 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Eng endoglin involved_in ISO (PMID:18974388)
(PMID:12015308)
RGD PMID:12015308 PMID:18974388 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Gdf1 growth differentiation factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519
JBrowse link
G Gdf10 growth differentiation factor 10 involved_in ISS
IBA
ISO
IEA
GO_REF:0000024
PMID:21873635
(MGI:5545973|PMID:21712809)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21712809 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5545973, RGD:13792537 NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
JBrowse link
G Gdf11 growth differentiation factor 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
JBrowse link
G Gdf15 growth differentiation factor 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO
IBA
(PMID:17068149), (PMID:19366699), (PMID:19903896)
PMID:21873635
RGD PMID:17068149 PMID:19366699 PMID:19903896 PMID:21873635 RGD:13792537 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Gdf3 growth differentiation factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
IBA
(PMID:16049014)
PMID:21873635
RGD PMID:16049014 PMID:21873635 RGD:13792537 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567
JBrowse link
G Gdf7 growth differentiation factor 7 involved_in ISO
IBA
(PMID:16049014)
PMID:21873635
RGD PMID:16049014 PMID:21873635 RGD:13792537 NCBI chr 6:31,171,495...31,182,447
Ensembl chr 6:31,178,119...31,182,447
JBrowse link
G Gdf9 growth differentiation factor 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24904118) RGD PMID:24904118 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Inha inhibin subunit alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
IBA
(PMID:19736306)
PMID:21873635
RGD PMID:19736306 PMID:21873635 RGD:13792537 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbb inhibin subunit beta B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Inhbc inhibin subunit beta C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
JBrowse link
G Inhbe inhibin subunit beta E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Lefty1 left right determination factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
G Lefty2 Left-right determination factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,610,185...92,620,918
Ensembl chr13:92,615,360...92,619,880
JBrowse link
G Lgals9 galectin 9 involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mstn myostatin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO
IBA
(PMID:21741376)
PMID:21873635
RGD PMID:21741376 PMID:21873635 RGD:13792537 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:31023188)
UniProtKB:Q91ZX7 (MGI:6434720|PMID:31023188)
RGD PMID:31023188 MGI:6434720 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor involved_in ISO (PMID:17099224) RGD PMID:17099224 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G Sdcbp syndecan binding protein involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:12065756)
(PMID:19736306), (PMID:26634652), (PMID:28467929), (PMID:31023188), (PMID:9389648)
UniProt
RGD
PMID:9389648 PMID:12065756 PMID:19736306 PMID:26634652 PMID:28467929 More... GO_REF:0000024, RGD:13792537 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IBA
(PMID:18358889)
PMID:21873635
RGD PMID:18358889 PMID:21873635 RGD:13792537 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
IBA
(MGI:2683382|PMID:14691138)
PMID:21873635
RGD PMID:14691138 PMID:21873635 MGI:2683382, RGD:13792537 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:12065756), (PMID:9311995), (PMID:9389648) RGD PMID:9311995 PMID:9389648 PMID:12065756 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (PMID:12065756) RGD PMID:12065756 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479
JBrowse link
positive regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18382765)
(PMID:20427544), (PMID:24778011)
(PMID:24778011)
GO_REF:0000107
(MGI:3795340|PMID:18382765)
RGD
Ensembl
PMID:18382765 PMID:20427544 PMID:24778011 GO_REF:0000107 MGI:3795340 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9389648)
UniProt
Ensembl
RGD
PMID:9389648 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (MGI:4352622|PMID:19252488) RGD PMID:19252488 MGI:4352622 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:20427544) RGD PMID:20427544 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:9389648)
(PMID:24882581), (PMID:9389648)
RGD PMID:9389648 PMID:24882581 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 acts_upstream_of_or_within ISO UniProtKB:P12643 (PMID:18382765) RGD PMID:18382765 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11387212)
Ensembl
RGD
PMID:11387212 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO UniProtKB:Q5VV43 (PMID:28334068) RGD PMID:28334068 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21741376) RGD PMID:21741376 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Nup93 nucleoporin 93 involved_in ISO
ISS
(PMID:26878725)
(MGI:5787706|PMID:26878725)
GO_REF:0000024
RGD
UniProt
PMID:26878725 GO_REF:0000024 MGI:5787706 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:31023188)
UniProtKB:Q91ZX7 (MGI:6434720|PMID:31023188)
RGD PMID:31023188 MGI:6434720 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor involved_in ISO (PMID:17099224) RGD PMID:17099224 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G RGD1307443 similar to mKIAA0319 protein acts_upstream_of_or_within ISO UniProtKB:O60674|UniProtKB:Q9NRF2 (PMID:28334068) RGD PMID:28334068 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Sh2b1 SH2B adaptor protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:Q5VV43 (PMID:28334068)
GO_REF:0000107
RGD
Ensembl
PMID:28334068 GO_REF:0000107 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579
JBrowse link
G Smad4 SMAD family member 4 involved_in ISO
IEA
(MGI:2683382|PMID:14691138)
GO_REF:0000107
RGD
Ensembl
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19366691), (PMID:28467929), (PMID:29167509), (PMID:31023188), (PMID:9389648)
AgBase
RGD
PMID:9389648 PMID:19366691 PMID:28467929 PMID:29167509 PMID:31023188 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:9389648) RGD PMID:9389648 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3829110|PMID:18625725) RGD PMID:18625725 MGI:3829110 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO MGI:1934919 (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3690196|PMID:16619037)
UniProt
RGD
PMID:16619037 GO_REF:0000024 MGI:3690196 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Crebbp CREB binding protein involved_in IEA
ISO
GO_REF:0000107
(PMID:25514493)
Ensembl
RGD
PMID:25514493 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11387212)
Ensembl
RGD
PMID:11387212 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:25514493) RGD PMID:25514493 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fermt1 FERM domain containing kindlin 1 involved_in ISO (MGI:5571208|PMID:24681597) RGD PMID:24681597 MGI:5571208 NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
MGI:4348628 (MGI:5050037|PMID:21258407)
(PMID:20573232)
UniProt
RGD
PMID:20573232 PMID:21258407 PMID:21873635 GO_REF:0000024 MGI:5050037, RGD:13792537 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) IMP RGD PMID:15194465 RGD:1582619 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO (MGI:3807767|PMID:11546783) RGD PMID:11546783 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:26880260 RGD:13504840 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) RGD PMID:14678985 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
ISS
(PMID:24613385)
GO_REF:0000024
RGD
UniProt
PMID:24613385 GO_REF:0000024 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Ing2 inhibitor of growth family, member 2 involved_in ISO (PMID:18334480) RGD PMID:18334480 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Itga8 integrin subunit alpha 8 acts_upstream_of_or_within ISO MGI:107430|MGI:2181699 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 acts_upstream_of_or_within
involved_in
ISO MGI:98725 (MGI:5543310|PMID:23868260)
(PMID:23868260), (PMID:32887674)
RGD PMID:23868260 PMID:32887674 MGI:5543310 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
JBrowse link
G Men1 menin 1 involved_in ISO (PMID:11274402) RGD PMID:11274402 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mir21 microRNA 21 acts_upstream_of ISO (PMID:31611175) RGD PMID:31611175 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir30b microRNA 30b involved_in ISO (PMID:28977001) RGD PMID:28977001 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
JBrowse link
G Myocd myocardin involved_in IEA
ISO
GO_REF:0000107
(MGI:3696631|PMID:16224064)
Ensembl
RGD
PMID:16224064 GO_REF:0000107 MGI:3696631 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Npnt nephronectin acts_upstream_of_or_within ISO MGI:3715213 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
JBrowse link
G RGD1311739 similar to RIKEN cDNA 1700037H04 involved_in ISO (PMID:32024300) RGD PMID:32024300 NCBI chr 3:118,364,730...118,378,881
Ensembl chr 3:118,362,363...118,378,838
JBrowse link
G Rnf111 ring finger protein 111 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3628833|PMID:16601693)
RGD PMID:16601693 PMID:21873635 MGI:3628833, RGD:13792537 NCBI chr 8:71,103,967...71,180,172
Ensembl chr 8:71,103,973...71,145,070
JBrowse link
G Sdcbp syndecan binding protein involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:26376865) RGD PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:19328798)
Ensembl
RGD
PMID:19328798 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:11278756) RGD PMID:11278756 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (PMID:18311138)
(MGI:3788958|PMID:18311138)
RGD PMID:18311138 MGI:3788958 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within IMP
ISO
(MGI:5617089|PMID:25382630) RGD PMID:25382630 PMID:8106553 MGI:5617089, RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18555217)
(MGI:1270011|PMID:9657149)
RGD PMID:9657149 PMID:18555217 MGI:1270011 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO (PMID:30592286) RGD PMID:30592286 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    positive regulation of biological process 6767
      positive regulation of signaling 2003
        positive regulation of signal transduction 1675
          positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 126
            positive regulation of BMP signaling pathway + 43
            positive regulation of SMAD protein signal transduction 20
            positive regulation of activin receptor signaling pathway + 10
            positive regulation of pathway-restricted SMAD protein phosphorylation 50
            positive regulation of transforming growth factor beta receptor signaling pathway 34
Path 2
Term Annotations click to browse term
  biological_process 19876
    biological regulation 13525
      regulation of biological process 13078
        regulation of cellular process 12401
          signal transduction 7117
            cell surface receptor signaling pathway 2859
              enzyme-linked receptor protein signaling pathway 1041
                transmembrane receptor protein serine/threonine kinase signaling pathway 421
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 287
                    positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 126
                      positive regulation of BMP signaling pathway + 43
                      positive regulation of SMAD protein signal transduction 20
                      positive regulation of activin receptor signaling pathway + 10
                      positive regulation of pathway-restricted SMAD protein phosphorylation 50
                      positive regulation of transforming growth factor beta receptor signaling pathway 34
paths to the root