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ONTOLOGY REPORT - ANNOTATIONS

Term:primitive streak formation
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Accession:GO:0090009 term browser browse the term
Definition:The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.


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primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ets2 ETS proto-oncogene 2, transcription factor acts_upstream_of_or_within ISO MGI:1891557 (MGI:5546318|PMID:23552073) RGD PMID:23552073 MGI:5546318 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319 		JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857725 (MGI:2157654|PMID:11291865)		 UniProt
RGD		 PMID:11291865 GO_REF:0000024 MGI:2157654 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gdf3 growth differentiation factor 3 acts_upstream_of_or_within ISO MGI:3612535 (MGI:3611720|PMID:16368929) RGD PMID:16368929 MGI:3611720 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:4999724|MGI:97359 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857502|MGI:1857848 (MGI:2157654|PMID:11291865)		 UniProt
RGD		 PMID:11291865 GO_REF:0000024 MGI:2157654 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:96086 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:1857502 (MGI:2157654|PMID:11291865) RGD PMID:11291865 MGI:2157654 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 MGI:4356107 (MGI:4355755|PMID:19706528)
GO_REF:0000107		 RGD
Ensembl		 PMID:19706528 GO_REF:0000107 MGI:4355755 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2158696 (MGI:1312998|PMID:9799237) RGD PMID:9799237 MGI:1312998 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1298218 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zic3 Zic family member 3 involved_in ISO MGI:2180720 (MGI:3617674|PMID:16397896) RGD PMID:16397896 MGI:3617674 NCBI chr  X:136,123,662...136,134,295
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    developmental process 7023
      anatomical structure formation involved in morphogenesis 1348
        primitive streak formation 12
          Wnt signaling pathway involved in primitive streak formation 0
          transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
Path 2
Term Annotations click to browse term
  biological_process 19903
    developmental process 7023
      anatomical structure development 6456
        multicellular organism development 5242
          embryo development 1373
            embryonic morphogenesis 702
              gastrulation 216
                gastrulation with mouth forming second 37
                  primitive streak formation 12
                    Wnt signaling pathway involved in primitive streak formation 0
                    transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
paths to the root