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ONTOLOGY REPORT - ANNOTATIONS

Term:primitive streak formation
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Accession:GO:0090009 term browser browse the term
Definition:The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.

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primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ets2 ETS proto-oncogene 2, transcription factor acts_upstream_of_or_within ISO MGI:1891557 (MGI:5546318|PMID:23552073) RGD PMID:23552073 MGI:5546318 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495 		JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857725 (MGI:2157654|PMID:11291865)		 UniProt
RGD		 PMID:11291865 GO_REF:0000024 MGI:2157654 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481 		JBrowse link
G Gdf3 growth differentiation factor 3 acts_upstream_of_or_within ISO MGI:3612535 (MGI:3611720|PMID:16368929) RGD PMID:16368929 MGI:3611720 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:4999724|MGI:97359 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857502|MGI:1857848 (MGI:2157654|PMID:11291865)		 UniProt
RGD		 PMID:11291865 GO_REF:0000024 MGI:2157654 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293 		JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:98958 (MGI:4413372|PMID:19795512)		 RGD PMID:19795512, PMID:21873635 MGI:4413372, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:96086 (MGI:4950786|PMID:21445260) RGD PMID:21445260 MGI:4950786 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:1857502 (MGI:2157654|PMID:11291865) RGD PMID:11291865 MGI:2157654 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
Ensembl chr15:25,502,019...25,505,691 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2158696 (MGI:1312998|PMID:9799237) RGD PMID:9799237 MGI:1312998 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225 		JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1298218 (MGI:4413372|PMID:19795512)		 Ensembl
RGD		 PMID:19795512 GO_REF:0000107 MGI:4413372 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure formation involved in morphogenesis 1215
        primitive streak formation 10
          Wnt signaling pathway involved in primitive streak formation 0
          transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
Path 2
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure development 6259
        multicellular organism development 5741
          embryo development 1306
            embryonic morphogenesis 688
              gastrulation 206
                gastrulation with mouth forming second 38
                  primitive streak formation 10
                    Wnt signaling pathway involved in primitive streak formation 0
                    transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
paths to the root