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ONTOLOGY REPORT - ANNOTATIONS


Term:primitive streak formation
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Accession:GO:0090009 term browser browse the term
Definition:The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
Synonyms:xref: Reactome:R-HSA-9754189 "Germ layer formation at gastrulation"



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primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ets2 ETS proto-oncogene 2, transcription factor acts_upstream_of_or_within ISO
IEA
MGI:1891557 (PMID:23552073)
GO_REF:0000107
RGD
Ensembl
PMID:23552073 GO_REF:0000107 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857725 (PMID:11291865)
UniProt
RGD
PMID:11291865 GO_REF:0000024 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Gdf3 growth differentiation factor 3 acts_upstream_of_or_within ISO
IEA
MGI:3612535 (PMID:16368929)
GO_REF:0000107
RGD
Ensembl
PMID:16368929 GO_REF:0000107 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO
IEA
MGI:4999724|MGI:97359 (PMID:21445260)
GO_REF:0000107
RGD
Ensembl
PMID:21445260 GO_REF:0000107 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:1857502|MGI:1857848 (PMID:11291865)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:11291865 GO_REF:0000024 GO_REF:0000107 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (PMID:19795512) RGD PMID:19795512 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:96086 (PMID:14511481), (PMID:21445260)
Ensembl
RGD
PMID:14511481 PMID:21445260 GO_REF:0000107 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within
involved_in
ISO MGI:1857502 (PMID:11291865) RGD PMID:11291865 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in IEA
ISO
GO_REF:0000107
MGI:4356107 (PMID:19706528)
Ensembl
RGD
PMID:19706528 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO
IEA
MGI:2158696 (PMID:9799237)
GO_REF:0000107
RGD
Ensembl
PMID:9799237 GO_REF:0000107 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA
MGI:1298218 (PMID:19795512)
GO_REF:0000107
RGD
Ensembl
PMID:19795512 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Zic3 Zic family member 3 involved_in ISO MGI:2180720 (PMID:16397896) RGD PMID:16397896 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure formation involved in morphogenesis 1384
        primitive streak formation 12
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          embryo development 1381
            embryonic morphogenesis 708
              gastrulation 216
                gastrulation with mouth forming second 37
                  primitive streak formation 12
paths to the root