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ONTOLOGY REPORT - ANNOTATIONS


Term:SA node cell to atrial cardiac muscle cell communication
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Accession:GO:0086070 term browser browse the term
Definition:The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
Synonyms:exact_synonym: SA node cardiac muscle cell to atrial cardiac muscle cell communication;   SA node cardiomyocyte to atrial cardiomyocyte communication;   SAN cardiomyocyte to atrial cardiomyocyte communication;   sinoatrial node cardiomyocyte to atrial cardiomyocyte communication
 narrow_synonym: sinus node cardiomyocyte to atrial cardiomyocyte communication



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SA node cell to atrial cardiac muscle cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597), (PMID:18832177), (PMID:21859974) BHF-UCL
BHF-UCL
PMID:12571597 PMID:18832177 PMID:21859974 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in TAS (PMID:19098452) BHF-UCL
BHF-UCL
PMID:19098452 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21131953)
(MGI:3583874|PMID:12700358)
BHF-UCL
MGI
BHF-UCL
PMID:12700358 PMID:21131953 MGI:3583874 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:16407510) BHF-UCL
BHF-UCL
PMID:16407510 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL
BHF-UCL
PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in TAS
IMP
(PMID:10820151)
(PMID:19343045)
BHF-UCL
BHF-UCL
PMID:10820151 PMID:19343045 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
regulation of SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597), (PMID:18832177) BHF-UCL
BHF-UCL
PMID:12571597 PMID:18832177 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in NAS (PMID:16043489) ComplexPortal PMID:16043489 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 involved_in NAS (PMID:12968185) ComplexPortal PMID:12968185 NCBI chr19:589,881...617,159
Ensembl chr19:589,881...617,159
JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 involved_in NAS (PMID:16043489) ComplexPortal PMID:16043489 NCBI chr 1:155,277,463...155,289,848
Ensembl chr 1:155,277,463...155,289,848
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in NAS (PMID:20829353) ComplexPortal PMID:20829353 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL
BHF-UCL
PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G TBX18 T-box transcription factor 18 acts_upstream_of IMP (PMID:23242162) BHF-UCL
BHF-UCL
PMID:23242162 NCBI chr 6:84,732,496...84,764,598
Ensembl chr 6:84,687,351...84,764,598
JBrowse link
SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3664488|PMID:11046183) MGI PMID:11046183 MGI:3664488 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:12750403) BHF-UCL
BHF-UCL
PMID:12750403 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL
BHF-UCL
PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
SA node cell to atrial cardiac muscle cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in NAS (PMID:15044680), (PMID:21357845) BHF-UCL
BHF-UCL
PMID:15044680 PMID:21357845 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJC1 gap junction protein gamma 1 involved_in NAS (PMID:21357845) BHF-UCL
BHF-UCL
PMID:21357845 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
SA node cell to atrial cardiac muscle cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19771
    cellular process 18049
      cell communication 7302
        cell communication involved in cardiac conduction 65
          SA node cell to atrial cardiac muscle cell communication 14
            SA node cell to atrial cardiac muscle cell communication by electrical coupling 2
            SA node cell to atrial cardiac muscle cell signaling + 13
            SA node cell-atrial cardiac muscle cell adhesion involved in cell communication 0
Path 2
Term Annotations click to browse term
  biological_process 19771
    multicellular organismal process 8918
      system process 2750
        circulatory system process 731
          blood circulation 646
            regulation of blood circulation 338
              regulation of heart contraction 261
                cardiac conduction 107
                  cell communication involved in cardiac conduction 65
                    SA node cell to atrial cardiac muscle cell communication 14
                      SA node cell to atrial cardiac muscle cell communication by electrical coupling 2
                      SA node cell to atrial cardiac muscle cell signaling + 13
                      SA node cell-atrial cardiac muscle cell adhesion involved in cell communication 0
paths to the root