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ONTOLOGY REPORT - ANNOTATIONS


Term:bundle of His cell to Purkinje myocyte communication
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Accession:GO:0086069 term browser browse the term
Definition:The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
Synonyms:exact_synonym: bundle of His cardiac muscle cell to Purkinje myocyte communication;   ventricular conduction system cell to cell communication
 narrow_synonym: atrioventricular junction myocyte to bundle branch myocyte;   bundle branch myocyte to Purkinje myocyte communication;   bundle of His myocyte to atrioventricular junction myocyte


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bundle of His cell to Purkinje myocyte communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnni3k TNNI3 interacting kinase involved_in ISO
ISS
(PMID:23236294)
GO_REF:0000024
RGD
BHF-UCL
PMID:23236294 GO_REF:0000024 NCBI chr 2:243,737,346...244,005,319
Ensembl chr 2:243,710,950...244,005,268
JBrowse link
bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in ISO (PMID:24998131) RGD PMID:24998131 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
ISS
(PMID:18065446)
GO_REF:0000024
RGD
BHF-UCL
PMID:18065446 GO_REF:0000024 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
bundle of His cell to Purkinje myocyte communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22247482)
(MGI:6101691|PMID:26786475)
RGD PMID:22247482 PMID:26786475 MGI:6101691 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5449667|PMID:22728936)
Ensembl
RGD
PMID:22728936 GO_REF:0000107 MGI:5449667 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
bundle of His cell-Purkinje myocyte adhesion involved in cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034767.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) RGD PMID:23136403 NCBI chr20:23,614,469...25,200,026 JBrowse link
G Dsc2 desmocollin 2 involved_in ISO (PMID:23863954) RGD PMID:23863954 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173) RGD PMID:16505173 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:12373648) RGD PMID:12373648 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Jup junction plakoglobin involved_in ISO (PMID:17924338) RGD PMID:17924338 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:84,661,783...84,727,730 JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA
(PMID:21383000)
GO_REF:0000107
RGD
Ensembl
PMID:21383000 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS
(PMID:18065446)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:18065446 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:23264583) RGD PMID:23264583 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
regulation of bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22247482)
(MGI:3696497|PMID:10515563)
RGD PMID:10515563 PMID:22247482 MGI:3696497 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell communication 7543
        cell communication involved in cardiac conduction 43
          bundle of His cell to Purkinje myocyte communication 16
            bundle of His cell to Purkinje myocyte communication by electrical coupling 2
            bundle of His cell to Purkinje myocyte signaling + 7
            bundle of His cell-Purkinje myocyte adhesion involved in cell communication 7
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of multicellular organismal process 2920
          regulation of system process 662
            regulation of blood circulation 278
              regulation of heart contraction 204
                cardiac conduction 69
                  cell communication involved in cardiac conduction 43
                    bundle of His cell to Purkinje myocyte communication 16
                      bundle of His cell to Purkinje myocyte communication by electrical coupling 2
                      bundle of His cell to Purkinje myocyte signaling + 7
                      bundle of His cell-Purkinje myocyte adhesion involved in cell communication 7
paths to the root