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ONTOLOGY REPORT - ANNOTATIONS


Term:voltage-gated sodium channel activity involved in bundle of His cell action potential
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Accession:GO:0086061 term browser browse the term
Definition:Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential



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voltage-gated sodium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn5a sodium voltage-gated channel alpha subunit 5 enables ISO
ISS
IEA
(PMID:18065446)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:18065446 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20893
    transporter activity 1260
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 750
          monoatomic ion channel activity 456
            monoatomic cation channel activity 345
              sodium channel activity 44
                voltage-gated sodium channel activity 26
                  voltage-gated sodium channel activity involved in cardiac muscle cell action potential 6
                    voltage-gated sodium channel activity involved in bundle of His cell action potential 1
Path 2
Term Annotations click to browse term
  molecular_function 20893
    transporter activity 1260
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 750
          monoatomic cation transmembrane transporter activity 628
            metal ion transmembrane transporter activity 456
              sodium ion transmembrane transporter activity 166
                sodium channel activity 44
                  voltage-gated sodium channel activity 26
                    voltage-gated sodium channel activity involved in cardiac muscle cell action potential 6
                      voltage-gated sodium channel activity involved in bundle of His cell action potential 1
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