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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane depolarization during bundle of His cell action potential
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Accession:GO:0086048 term browser browse the term
Definition:The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
Synonyms:exact_synonym: membrane depolarization during bundle of His cardiac muscle cell action potential


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membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO (PMID:21383000) BHF-UCL PMID:21383000 NCBI chr18:21,561,091...21,949,970
Ensembl chr18:21,564,676...21,949,544 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    biological regulation 12539
      regulation of biological quality 3357
        regulation of membrane potential 533
          action potential 200
            cardiac muscle cell action potential 68
              membrane depolarization during cardiac muscle cell action potential 17
                membrane depolarization during bundle of His cell action potential 3
Path 2
Term Annotations click to browse term
  biological_process 22103
    multicellular organismal process 8174
      system process 2921
        circulatory system process 605
          blood circulation 578
            regulation of blood circulation 294
              regulation of heart contraction 215
                cardiac conduction 71
                  cell communication involved in cardiac conduction 41
                    bundle of His cell to Purkinje myocyte communication 16
                      bundle of His cell to Purkinje myocyte signaling 8
                        bundle of His cell action potential 8
                          membrane depolarization during bundle of His cell action potential 3
paths to the root