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ONTOLOGY REPORT - ANNOTATIONS


Term:SA node cell action potential
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Accession:GO:0086015 term browser browse the term
Definition:An action potential that occurs in a sinoatrial node cardiac muscle cell.
Synonyms:exact_synonym: SA node cardiac muscle cell action potential;   SAN cardiac muscle cell action potential;   sinoatrial node cardiac muscle cell action potential
 narrow_synonym: sinus node cardiac muscle cell action potential


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SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO (MGI:MGI:5430886|PMID:18832177) BHF-UCL PMID:18832177 MGI:MGI:5430886 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO (MGI:MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:MGI:3714901 NCBI chrNW_004936490:11,093,600...11,157,756 JBrowse link
G Gja5 gap junction protein alpha 5 ISO (MGI:MGI:3664488|PMID:11046183) MGI PMID:11046183 MGI:MGI:3664488 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO (PMID:12750403) BHF-UCL PMID:12750403 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (MGI:MGI:5294533|PMID:19796257) BHF-UCL PMID:19796257 MGI:MGI:5294533 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO (PMID:21131953)
(MGI:MGI:3583874|PMID:12700358)
BHF-UCL
MGI
PMID:12700358, PMID:21131953 MGI:MGI:3583874 NCBI chrNW_004936473:4,164,633...4,479,866 JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO (MGI:MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:MGI:3714901 NCBI chrNW_004936490:11,093,600...11,157,756 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO (PMID:16407510) BHF-UCL PMID:16407510 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
regulation of SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO (PMID:12571597), (PMID:18832177)
(MGI:MGI:2449848|PMID:12571597)
BHF-UCL PMID:12571597, PMID:18832177 MGI:MGI:2449848 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Ryr2 ryanodine receptor 2 ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    signaling 4166
      cell-cell signaling 1360
        cell-cell signaling involved in cardiac conduction 23
          SA node cell to atrial cardiac muscle cell signaling 8
            SA node cell action potential 8
              membrane depolarization during SA node cell action potential 4
              membrane repolarization during SA node cell action potential 0
              regulation of SA node cell action potential 2
Path 2
Term Annotations click to browse term
  biological_process 11968
    multicellular organismal process 6224
      system process 1576
        circulatory system process 482
          blood circulation 459
            heart contraction 210
              regulation of heart contraction 178
                cardiac conduction 57
                  cell communication involved in cardiac conduction 36
                    SA node cell to atrial cardiac muscle cell communication 8
                      SA node cell to atrial cardiac muscle cell signaling 8
                        SA node cell action potential 8
                          membrane depolarization during SA node cell action potential 4
                          membrane repolarization during SA node cell action potential 0
                          regulation of SA node cell action potential 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.