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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during cardiac muscle cell action potential
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Accession:GO:0086013 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


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membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IC (PMID:19542013) BHF-UCL PMID:19542013 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in IC (PMID:19542013) BHF-UCL PMID:19542013 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,132,722
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in TAS (PMID:26016905) BHF-UCL PMID:26016905 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP
IDA
(PMID:10400998)
(PMID:8900283)
BHF-UCL PMID:8900283 PMID:10400998 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 involved_in TAS (PMID:26016905) BHF-UCL PMID:26016905 NCBI chr10:101,825,971...101,843,875
Ensembl chr10:101,825,974...101,843,920
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in TAS
IMP
(PMID:20086079)
(PMID:11371347)
BHF-UCL PMID:11371347 PMID:20086079 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP
TAS
(PMID:8528244)
(PMID:11299204)
BHF-UCL PMID:8528244 PMID:11299204 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IC (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,344,275...1,400,229
Ensembl chr17:1,344,275...1,400,222
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in IEA
ISS
(PMID:19139040) Ensembl
BHF-UCL
PMID:19139040 GO_REF:0000107 NCBI chr 5:114,055,978...114,496,500
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:23264583) BHF-UCL PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in TAS
IMP
(PMID:10820151)
(PMID:19343045)
BHF-UCL PMID:10820151 PMID:19343045 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE1B potassium voltage-gated channel subfamily E regulatory subunit 1B involved_in IEA GOC GO_REF:0000108 NCBI chr21:7,816,677...7,829,632
Ensembl chr21:7,816,675...7,829,926
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,051,814...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA GOC GO_REF:0000108 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IMP (PMID:20558321) BHF-UCL PMID:20558321 NCBI chr12:21,764,955...21,775,593
Ensembl chr12:21,764,955...21,775,600
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IBA
IMP
(PMID:21873635)
(PMID:8528244)
GO_Central
BHF-UCL
PMID:8528244 PMID:21873635 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP (PMID:22987075) BHF-UCL PMID:22987075 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF207 ring finger protein 207 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:6,206,004...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1AP nitric oxide synthase 1 adaptor protein involved_in ISS (PMID:18337493) BHF-UCL PMID:18337493 NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475
JBrowse link
G RNF207 ring finger protein 207 involved_in ISS
IMP
(PMID:25281747) BHF-UCL PMID:25281747 GO_REF:0000024 NCBI chr 1:6,206,004...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
regulation of membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in IC BHF-UCL GO_REF:0000111 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in ISS (PMID:24951510) BHF-UCL PMID:24951510 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    localization 6639
      establishment of localization 5030
        establishment of localization in cell 2313
          cardiac muscle cell membrane repolarization 36
            membrane repolarization during cardiac muscle cell action potential 22
              membrane repolarization during AV node cell action potential 0
              membrane repolarization during Purkinje myocyte action potential 0
              membrane repolarization during SA node cell action potential 1
              membrane repolarization during atrial cardiac muscle cell action potential + 6
              membrane repolarization during bundle of His cell action potential 1
              membrane repolarization during ventricular cardiac muscle cell action potential + 14
              negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
              positive regulation of membrane repolarization during cardiac muscle cell action potential + 2
              regulation of membrane repolarization during cardiac muscle cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 18537
    localization 6639
      establishment of localization 5030
        transport 4868
          ion transport 1696
            ion transmembrane transport 1200
              membrane repolarization 46
                cardiac muscle cell membrane repolarization 36
                  membrane repolarization during cardiac muscle cell action potential 22
                    membrane repolarization during AV node cell action potential 0
                    membrane repolarization during Purkinje myocyte action potential 0
                    membrane repolarization during SA node cell action potential 1
                    membrane repolarization during atrial cardiac muscle cell action potential + 6
                    membrane repolarization during bundle of His cell action potential 1
                    membrane repolarization during ventricular cardiac muscle cell action potential + 14
                    negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    positive regulation of membrane repolarization during cardiac muscle cell action potential + 2
                    regulation of membrane repolarization during cardiac muscle cell action potential + 4
paths to the root