Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:membrane depolarization during action potential
go back to main search page
Accession:GO:0086010 term browser browse the term
Definition:The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


show annotations for term's descendants           Sort by:
membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:20,463,511...20,595,253
Ensembl chr22:38,296,436...38,414,963 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:7604285) BHF-UCL PMID:7604285 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247 		JBrowse link
G SCN11A sodium voltage-gated channel alpha subunit 11 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:38,741,485...38,948,400
Ensembl chr 3:39,024,921...39,128,015 		JBrowse link
G SCN1A sodium voltage-gated channel alpha subunit 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:53,258,614...53,348,131
Ensembl chr2B:170,736,651...170,822,014 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052 		JBrowse link
G SCN2A sodium voltage-gated channel alpha subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:52,514,918...52,667,225
Ensembl chr2B:169,928,323...170,027,509 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,996,609...113,010,412
Ensembl chr11:116,928,676...116,942,500 		JBrowse link
G SCN3A sodium voltage-gated channel alpha subunit 3 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:52,363,020...52,479,818
Ensembl chr2B:169,722,134...169,838,590 		JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063 		JBrowse link
G SCN4A sodium voltage-gated channel alpha subunit 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:58,034,146...58,066,644
Ensembl chr17:63,128,550...63,161,043 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G SCN7A sodium voltage-gated channel alpha subunit 7 NOT|involved_in ISO
IEA		 PMID:9001394 UniProt
TreeGrafter		 PMID:9001394 GO_REF:0000118 RGD:61747 NCBI chr2B:53,676,298...53,768,289
Ensembl chr2B:171,151,969...171,243,717 		JBrowse link
G SCN8A sodium voltage-gated channel alpha subunit 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:36,950,057...37,172,235
Ensembl chr12:37,730,900...37,876,357 		JBrowse link
G SCN9A sodium voltage-gated channel alpha subunit 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:53,468,290...53,643,747
Ensembl chr2B:170,944,974...171,054,013 		JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:12,966,653...12,979,695
Ensembl chr22:30,819,821...30,831,804 		JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:73,917,439...74,410,627
Ensembl chr 7:87,579,004...88,068,482 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:112,996,609...113,010,412
Ensembl chr11:116,928,676...116,942,500 		JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,967,190...112,986,727
Ensembl chr11:116,899,268...116,918,892 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12700358) Ensembl
MGI		 PMID:12700358 GO_REF:0000107 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 involved_in ISO PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chr10:56,560,589...57,269,952
Ensembl chr10:58,790,696...59,602,954 		JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in ISO PMID:8816717 UniProt PMID:8816717 RGD:405650388 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049 		JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:80,528,896...80,651,629
Ensembl chr 9:108,699,761...108,787,464 		JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:9501070) MGI PMID:9501070 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413 		JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394 		JBrowse link
G SLMAP sarcolemma associated protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:57,688,669...57,864,355
Ensembl chr 3:59,108,247...59,280,713 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16786
    biological regulation 11730
      regulation of biological quality 3141
        regulation of membrane potential 524
          membrane depolarization 105
            membrane depolarization during action potential 32
              membrane depolarization during cardiac muscle cell action potential + 18
              regulation of membrane depolarization during action potential + 7
paths to the root