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ONTOLOGY REPORT - ANNOTATIONS


Term:voltage-gated sodium channel activity involved in cardiac muscle cell action potential
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Accession:GO:0086006 term browser browse the term
Definition:Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


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voltage-gated sodium channel activity involved in cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:1600115
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1600115
RGD:1624291
voltage-gated sodium channel activity involved in AV node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
voltage-gated sodium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
voltage-gated sodium channel activity involved in Purkinje myocyte action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
voltage-gated sodium channel activity involved in SA node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18245
    transporter activity 1178
      transmembrane transporter activity 1047
        ion transmembrane transporter activity 863
          ion channel activity 417
            cation channel activity 322
              sodium channel activity 39
                voltage-gated sodium channel activity 20
                  voltage-gated sodium channel activity involved in cardiac muscle cell action potential 5
                    voltage-gated sodium channel activity involved in AV node cell action potential 1
                    voltage-gated sodium channel activity involved in Purkinje myocyte action potential 2
                    voltage-gated sodium channel activity involved in SA node cell action potential 1
                    voltage-gated sodium channel activity involved in bundle of His cell action potential 1
Path 2
Term Annotations click to browse term
  molecular_function 18245
    transporter activity 1178
      transmembrane transporter activity 1047
        ion transmembrane transporter activity 863
          cation transmembrane transporter activity 635
            inorganic cation transmembrane transporter activity 587
              metal ion transmembrane transporter activity 439
                sodium ion transmembrane transporter activity 147
                  sodium channel activity 39
                    voltage-gated sodium channel activity 20
                      voltage-gated sodium channel activity involved in cardiac muscle cell action potential 5
                        voltage-gated sodium channel activity involved in AV node cell action potential 1
                        voltage-gated sodium channel activity involved in Purkinje myocyte action potential 2
                        voltage-gated sodium channel activity involved in SA node cell action potential 1
                        voltage-gated sodium channel activity involved in bundle of His cell action potential 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.