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ONTOLOGY REPORT - ANNOTATIONS

Term:voltage-gated sodium channel activity involved in cardiac muscle cell action potential
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Accession:GO:0086006 term browser browse the term
Definition:Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


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voltage-gated sodium channel activity involved in cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN10A sodium voltage-gated channel alpha subunit 10 enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr23:8,420,468...8,527,414
Ensembl chr23:8,420,472...8,527,383 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:117,504,428...117,510,666
Ensembl chr 1:117,503,828...117,511,727 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:15,514,760...15,534,179
Ensembl chr 5:15,521,481...15,534,179 		JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:10,783,235...10,808,342
Ensembl chr 5:10,783,325...10,804,242 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 enables ISO (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr 5:15,552,347...15,564,085
Ensembl chr 5:15,543,632...15,563,486 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
voltage-gated sodium channel activity involved in AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN5A sodium voltage-gated channel alpha subunit 5 enables IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
voltage-gated sodium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN5A sodium voltage-gated channel alpha subunit 5 enables IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
voltage-gated sodium channel activity involved in Purkinje myocyte action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN1B sodium voltage-gated channel beta subunit 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:117,504,428...117,510,666
Ensembl chr 1:117,503,828...117,511,727 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 enables IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
voltage-gated sodium channel activity involved in SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN5A sodium voltage-gated channel alpha subunit 5 enables IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        monoatomic ion transmembrane transporter activity 750
          monoatomic ion channel activity 467
            monoatomic cation channel activity 359
              sodium channel activity 45
                voltage-gated sodium channel activity 26
                  voltage-gated sodium channel activity involved in cardiac muscle cell action potential 6
                    voltage-gated sodium channel activity involved in AV node cell action potential 1
                    voltage-gated sodium channel activity involved in Purkinje myocyte action potential 2
                    voltage-gated sodium channel activity involved in SA node cell action potential 1
                    voltage-gated sodium channel activity involved in bundle of His cell action potential 1
Path 2
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        monoatomic ion transmembrane transporter activity 750
          monoatomic cation transmembrane transporter activity 627
            metal ion transmembrane transporter activity 450
              sodium ion transmembrane transporter activity 159
                sodium channel activity 45
                  voltage-gated sodium channel activity 26
                    voltage-gated sodium channel activity involved in cardiac muscle cell action potential 6
                      voltage-gated sodium channel activity involved in AV node cell action potential 1
                      voltage-gated sodium channel activity involved in Purkinje myocyte action potential 2
                      voltage-gated sodium channel activity involved in SA node cell action potential 1
                      voltage-gated sodium channel activity involved in bundle of His cell action potential 1
paths to the root