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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell action potential
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Accession:GO:0086001 term browser browse the term
Definition:An action potential that occurs in a cardiac muscle cell.


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cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:22,306,962...24,846,427
Ensembl chrNW_004624762:22,746,729...24,847,938
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 involved_in ISO PMID:9058605 UniProt PMID:9058605 RGD:10047324 NCBI chrNW_004624783:15,349,416...15,892,011
Ensembl chrNW_004624783:15,351,870...15,891,057
JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15581370) Ensembl
MGI
PMID:15581370 GO_REF:0000107 NCBI chrNW_004624801:365,393...375,802
Ensembl chrNW_004624801:365,361...374,487
JBrowse link
G Pkp2 plakophilin 2 ISO RGD PMID:19661460 RGD:6784504 NCBI chrNW_004624778:3,261,446...3,344,204
Ensembl chrNW_004624778:3,261,390...3,342,850
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276), (PMID:18832177), (PMID:21859974)
(PMID:21859974)
BHF-UCL PMID:17242276 PMID:18832177 PMID:21859974 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chrNW_004624860:2,042,325...2,045,953
Ensembl chrNW_004624860:2,039,771...2,045,867
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) BHF-UCL PMID:18313602 NCBI chrNW_004624803:6,385,405...6,385,876 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) BHF-UCL PMID:12522251 NCBI chrNW_004624767:15,252,961...15,613,373
Ensembl chrNW_004624767:15,252,950...15,613,562
JBrowse link
G Nup155 nucleoporin 155 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19070573) Ensembl
MGI
PMID:19070573 GO_REF:0000107 NCBI chrNW_004624759:17,682,816...17,760,448
Ensembl chrNW_004624759:17,682,837...17,761,531
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624880:1,496,571...1,519,728
Ensembl chrNW_004624880:1,496,634...1,516,684
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in ISO (PMID:24998131) BHF-UCL PMID:24998131 NCBI chrNW_004624731:2,254,445...2,356,174
Ensembl chrNW_004624731:2,254,445...2,355,738
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:13,550,950...13,569,937
Ensembl chrNW_004624784:13,549,815...13,570,026
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in ISO (PMID:24998131) BHF-UCL PMID:24998131 NCBI chrNW_004624731:2,254,445...2,356,174
Ensembl chrNW_004624731:2,254,445...2,355,738
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078) BHF-UCL PMID:15454078 NCBI chrNW_004624735:10,201,030...10,927,349
Ensembl chrNW_004624735:10,201,526...10,432,896
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISO (PMID:21131953) BHF-UCL PMID:21131953 NCBI chrNW_004624822:3,391,045...3,734,258
Ensembl chrNW_004624822:3,392,044...3,919,415
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO (PMID:25527503) BHF-UCL PMID:25527503 NCBI chrNW_004624739:30,436,662...30,864,482
Ensembl chrNW_004624739:30,436,568...30,864,468
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998) BHF-UCL PMID:10400998 NCBI chrNW_004624745:22,624,414...22,631,625
Ensembl chrNW_004624745:22,624,765...22,631,609
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chrNW_004624745:22,552,809...22,553,321
Ensembl chrNW_004624745:22,525,037...22,556,000
JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:365,393...375,802
Ensembl chrNW_004624801:365,361...374,487
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004624778:3,261,446...3,344,204
Ensembl chrNW_004624778:3,261,390...3,342,850
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004624787:3,767,405...3,939,065
Ensembl chrNW_004624787:3,768,120...3,908,889
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624794:8,439,609...8,449,731
Ensembl chrNW_004624794:8,439,600...8,450,179
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:13,580,427...13,593,055
Ensembl chrNW_004624784:13,580,313...13,593,169
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624880:1,496,571...1,519,728
Ensembl chrNW_004624880:1,496,634...1,516,684
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624784:13,550,950...13,569,937
Ensembl chrNW_004624784:13,549,815...13,570,026
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:21895525) BHF-UCL PMID:21895525 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chrNW_004624735:10,201,030...10,927,349
Ensembl chrNW_004624735:10,201,526...10,432,896
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chrNW_004624796:9,502,132...9,858,836
Ensembl chrNW_004624796:9,503,452...9,859,019
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:26253506) BHF-UCL PMID:26253506 NCBI chrNW_004624735:10,201,030...10,927,349
Ensembl chrNW_004624735:10,201,526...10,432,896
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chrNW_004624796:9,502,132...9,858,836
Ensembl chrNW_004624796:9,503,452...9,859,019
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO (PMID:21383000) BHF-UCL PMID:21383000 NCBI chrNW_004624739:30,436,662...30,864,482
Ensembl chrNW_004624739:30,436,568...30,864,468
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078) BHF-UCL PMID:15454078 NCBI chrNW_004624735:10,201,030...10,927,349
Ensembl chrNW_004624735:10,201,526...10,432,896
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624731:2,254,445...2,356,174
Ensembl chrNW_004624731:2,254,445...2,355,738
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO (PMID:19808477)
(PMID:17884088)
BHF-UCL PMID:17884088 PMID:19808477 NCBI chrNW_004624794:8,439,609...8,449,731
Ensembl chrNW_004624794:8,439,600...8,450,179
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:13,580,427...13,593,055
Ensembl chrNW_004624784:13,580,313...13,593,169
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624880:1,496,571...1,519,728
Ensembl chrNW_004624880:1,496,634...1,516,684
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:13,550,950...13,569,937
Ensembl chrNW_004624784:13,549,815...13,570,026
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO (PMID:18464934) BHF-UCL PMID:18464934 NCBI chrNW_004624794:8,439,609...8,449,731
Ensembl chrNW_004624794:8,439,600...8,450,179
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:22766342) BHF-UCL PMID:22766342 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
ISO (PMID:21131953)
(PMID:12700358)
BHF-UCL
MGI
PMID:12700358 PMID:21131953 NCBI chrNW_004624822:3,391,045...3,734,258
Ensembl chrNW_004624822:3,392,044...3,919,415
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in ISO (PMID:16407510) BHF-UCL PMID:16407510 NCBI chrNW_004624781:968,608...1,007,969
Ensembl chrNW_004624781:968,748...1,008,200
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chrNW_004624860:2,042,325...2,045,953
Ensembl chrNW_004624860:2,039,771...2,045,867
JBrowse link
G Kcnj5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624812:3,213,619...3,243,514
Ensembl chrNW_004624812:3,213,774...3,244,012
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (PMID:19139040) BHF-UCL PMID:19139040 NCBI chrNW_004624733:7,429,681...7,931,192
Ensembl chrNW_004624733:7,429,681...7,578,596
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chrNW_004624767:15,252,961...15,613,373
Ensembl chrNW_004624767:15,252,950...15,613,562
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:23264583) BHF-UCL PMID:23264583 NCBI chrNW_004624860:2,042,325...2,045,953
Ensembl chrNW_004624860:2,039,771...2,045,867
JBrowse link
membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:8900283)
(PMID:10400998)
BHF-UCL PMID:8900283 PMID:10400998 NCBI chrNW_004624745:22,624,414...22,631,625
Ensembl chrNW_004624745:22,624,765...22,631,609
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624800:5,633,060...5,663,700
Ensembl chrNW_004624800:5,632,726...5,663,771
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624849:1,043,045...1,063,371
Ensembl chrNW_004624849:1,043,045...1,062,891
JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:365,393...375,802
Ensembl chrNW_004624801:365,361...374,487
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004624767:15,252,961...15,613,373
Ensembl chrNW_004624767:15,252,950...15,613,562
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045) BHF-UCL PMID:19343045 NCBI chrNW_004624860:2,042,325...2,045,953
Ensembl chrNW_004624860:2,039,771...2,045,867
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO (PMID:25447080) BHF-UCL PMID:25447080 NCBI chrNW_004624730:62,001,547...62,223,098
Ensembl chrNW_004624730:62,002,280...62,223,319
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chrNW_004624745:22,624,414...22,631,625
Ensembl chrNW_004624745:22,624,765...22,631,609
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624745:22,552,809...22,553,321
Ensembl chrNW_004624745:22,525,037...22,556,000
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624817:2,593,649...2,607,462
Ensembl chrNW_004624817:2,513,539...2,606,682
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624823:2,239,132...2,244,758
Ensembl chrNW_004624823:2,239,101...2,266,809
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624803:6,385,405...6,385,876 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004624800:5,633,060...5,663,700
Ensembl chrNW_004624800:5,632,726...5,663,771
JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:16,939,289...16,945,692
Ensembl chrNW_004624752:16,939,384...16,946,723
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:8528244)
(PMID:12766260), (PMID:15004216)
BHF-UCL
MGI
PMID:8528244 PMID:12766260 PMID:15004216 NCBI chrNW_004624767:15,252,961...15,613,373
Ensembl chrNW_004624767:15,252,950...15,613,562
JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:3,348,172...3,363,772
Ensembl chrNW_004624731:3,347,984...3,364,581
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) BHF-UCL PMID:22987075 NCBI chrNW_004624817:2,593,649...2,607,462
Ensembl chrNW_004624817:2,513,539...2,606,682
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO (PMID:24836577) ARUK-UCL PMID:24836577 NCBI chrNW_004624732:13,543,975...13,592,942
Ensembl chrNW_004624732:13,544,507...13,592,795
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 involved_in ISO PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chrNW_004624791:3,299,287...3,633,631 JBrowse link
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 acts_upstream_of ISO (PMID:25281747) BHF-UCL PMID:25281747 NCBI chrNW_004624818:5,176,316...5,183,610
Ensembl chrNW_004624818:5,178,299...5,183,610
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597) BHF-UCL PMID:12571597 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Gja5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004624775:12,954,653...13,650,449
Ensembl chrNW_004624775:12,956,042...13,419,381
JBrowse link
regulation of AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597) BHF-UCL PMID:12571597 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Cxadr CXADR Ig-like cell adhesion molecule involved_in ISO (PMID:18636119) BHF-UCL PMID:18636119 NCBI chrNW_004624745:5,900,933...5,954,584
Ensembl chrNW_004624745:5,900,886...5,958,765
JBrowse link
G Gja5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004624775:12,954,653...13,650,449
Ensembl chrNW_004624775:12,956,042...13,419,381
JBrowse link
regulation of bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chrNW_004624786:10,866,724...10,868,136
Ensembl chrNW_004624786:10,866,834...10,867,983
JBrowse link
regulation of cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:12,030,264...12,041,682
Ensembl chrNW_004624734:12,030,001...12,041,772
JBrowse link
G Calm2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,525,290...28,541,562
Ensembl chrNW_004624738:28,525,285...28,541,514
JBrowse link
G Calm3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:6,957,775...6,966,505
Ensembl chrNW_004624832:6,958,820...6,966,514
JBrowse link
G Slc4a3 solute carrier family 4 member 3 involved_in ISO (PMID:29167417) UniProt PMID:29167417 NCBI chrNW_004624823:5,440,213...5,453,683
Ensembl chrNW_004624823:5,439,336...5,453,801
JBrowse link
G Tmem161b transmembrane protein 161B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:7,545,374...7,612,893
Ensembl chrNW_004624743:7,545,579...7,612,877
JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) BHF-UCL PMID:18093912 NCBI chrNW_004624809:1,101,941...1,258,402
Ensembl chrNW_004624809:1,103,538...1,257,809
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISO PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chrNW_004624747:21,509,360...21,567,424
Ensembl chrNW_004624747:21,509,366...21,568,098
JBrowse link
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:3,348,172...3,363,772
Ensembl chrNW_004624731:3,347,984...3,364,581
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624808:7,577,422...8,091,216
Ensembl chrNW_004624808:7,578,286...8,091,811
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in ISO (PMID:16407510) BHF-UCL PMID:16407510 NCBI chrNW_004624781:968,608...1,007,969
Ensembl chrNW_004624781:968,748...1,008,200
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chrNW_004624786:10,866,724...10,868,136
Ensembl chrNW_004624786:10,866,834...10,867,983
JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:3,348,172...3,363,772
Ensembl chrNW_004624731:3,347,984...3,364,581
JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:9501070) MGI PMID:9501070 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chrNW_004624786:10,866,724...10,868,136
Ensembl chrNW_004624786:10,866,834...10,867,983
JBrowse link
G Slmap sarcolemma associated protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624821:493,902...638,553
Ensembl chrNW_004624821:493,735...639,801
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flna filamin A involved_in ISO (PMID:24951510) BHF-UCL PMID:24951510 NCBI chrNW_004624946:812,278...836,307
Ensembl chrNW_004624946:812,287...837,273
JBrowse link
regulation of Purkinje myocyte action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
regulation of SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597), (PMID:18832177) BHF-UCL PMID:12571597 PMID:18832177 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004624775:12,954,653...13,650,449
Ensembl chrNW_004624775:12,956,042...13,419,381
JBrowse link
G Tbx18 T-box transcription factor 18 acts_upstream_of ISO (PMID:23242162) BHF-UCL PMID:23242162 NCBI chrNW_004624799:9,694,167...9,721,468
Ensembl chrNW_004624799:9,694,374...9,719,385
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078), (PMID:26253506) BHF-UCL PMID:15454078 PMID:26253506 NCBI chrNW_004624735:10,201,030...10,927,349
Ensembl chrNW_004624735:10,201,526...10,432,896
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:25017399) BHF-UCL PMID:25017399 NCBI chrNW_004624827:2,844,855...2,878,367
Ensembl chrNW_004624827:2,844,115...2,879,179
JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) BHF-UCL PMID:23136403 NCBI chrNW_004624754:285,469...2,182,218
Ensembl chrNW_004624754:285,857...2,034,582
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO (PMID:25447080) BHF-UCL PMID:25447080 NCBI chrNW_004624730:62,001,547...62,223,098
Ensembl chrNW_004624730:62,002,280...62,223,319
JBrowse link
G Dsc2 desmocollin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:1,748,561...1,778,566
Ensembl chrNW_004624770:1,748,276...1,781,117
JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chrNW_004624770:1,315,021...1,363,472
Ensembl chrNW_004624770:1,313,916...1,364,153
JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:12373648) BHF-UCL PMID:12373648 NCBI chrNW_004624756:18,036,103...18,083,379
Ensembl chrNW_004624756:18,035,892...18,083,336
JBrowse link
G Jup junction plakoglobin involved_in ISO (PMID:17924338) BHF-UCL PMID:17924338 NCBI chrNW_004624795:1,954,733...1,972,080
Ensembl chrNW_004624795:1,954,290...1,975,018
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004624778:3,261,446...3,344,204
Ensembl chrNW_004624778:3,261,390...3,342,850
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004624775:12,954,653...13,650,449
Ensembl chrNW_004624775:12,956,042...13,419,381
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:18832177) BHF-UCL PMID:18832177 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:11046183) MGI PMID:11046183 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in ISO (PMID:12750403) BHF-UCL PMID:12750403 NCBI chrNW_004624781:968,608...1,007,969
Ensembl chrNW_004624781:968,748...1,008,200
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624880:1,496,571...1,519,728
Ensembl chrNW_004624880:1,496,634...1,516,684
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18616619) BHF-UCL PMID:18616619 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276) BHF-UCL PMID:17242276 NCBI chrNW_004624838:6,490,434...7,023,945
Ensembl chrNW_004624838:6,548,159...7,023,945
JBrowse link
G Cav3 caveolin 3 involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chrNW_004624731:3,348,172...3,363,772
Ensembl chrNW_004624731:3,347,984...3,364,581
JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:9501070) MGI PMID:9501070 NCBI chrNW_004624772:16,810,723...16,828,328
Ensembl chrNW_004624772:16,813,011...16,814,084
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977 PMID:19666841 NCBI chrNW_004624788:10,173,629...10,240,200
Ensembl chrNW_004624788:10,173,551...10,240,704
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:22,624,414...22,631,625
Ensembl chrNW_004624745:22,624,765...22,631,609
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18603586) MGI
TreeGrafter
PMID:18603586 GO_REF:0000118 NCBI chrNW_004624745:22,552,809...22,553,321
Ensembl chrNW_004624745:22,525,037...22,556,000
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624817:2,593,649...2,607,462
Ensembl chrNW_004624817:2,513,539...2,606,682
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:2,239,132...2,244,758
Ensembl chrNW_004624823:2,239,101...2,266,809
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624803:6,385,405...6,385,876 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004624800:5,633,060...5,663,700
Ensembl chrNW_004624800:5,632,726...5,663,771
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004624767:15,252,961...15,613,373
Ensembl chrNW_004624767:15,252,950...15,613,562
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chrNW_004624792:3,553,185...3,903,288
Ensembl chrNW_004624792:3,553,004...3,902,468
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004624778:3,261,446...3,344,204
Ensembl chrNW_004624778:3,261,390...3,342,850
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17872467) BHF-UCL PMID:17872467 NCBI chrNW_004624775:12,954,653...13,650,449
Ensembl chrNW_004624775:12,956,042...13,419,381
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19351516) Ensembl
TreeGrafter
MGI
PMID:19351516 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624880:1,496,571...1,519,728
Ensembl chrNW_004624880:1,496,634...1,516,684
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:22529811) BHF-UCL PMID:22529811 NCBI chrNW_004624731:2,401,358...2,498,212
Ensembl chrNW_004624731:2,401,380...2,498,211
JBrowse link
G Snta1 syntrophin alpha 1 involved_in ISO (PMID:18591664) BHF-UCL PMID:18591664 NCBI chrNW_004624842:5,805,409...5,834,553
Ensembl chrNW_004624842:5,805,342...5,834,022
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17638
    biological regulation 11844
      regulation of biological quality 3007
        regulation of membrane potential 498
          action potential 184
            cardiac muscle cell action potential 60
              AV node cell action potential + 10
              Purkinje myocyte action potential + 4
              SA node cell action potential + 9
              bundle of His cell action potential + 7
              cardiac muscle cell action potential involved in contraction + 41
              membrane depolarization during cardiac muscle cell action potential + 17
              membrane repolarization during cardiac muscle cell action potential + 16
              regulation of cardiac muscle cell action potential + 27
paths to the root