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ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis

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lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:7,206,226...7,232,798
Ensembl chrNW_004936502:7,206,172...7,233,912 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:41,083,713...41,087,106
Ensembl chrNW_004936469:41,083,738...41,087,087 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936501:11,955,334...11,967,338
Ensembl chrNW_004936501:11,955,184...11,967,436 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:4,283,016...4,291,968
Ensembl chrNW_004936511:4,283,009...4,292,376 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:28,069,058...28,084,607
Ensembl chrNW_004936471:28,070,462...28,084,648 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004936481:18,523,022...18,531,227 JBrowse link
G Grn granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:793,548...800,271
Ensembl chrNW_004936541:793,523...800,217 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:377,359...389,121
Ensembl chrNW_004936472:378,173...389,381 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:9,584,221...9,622,330
Ensembl chrNW_004936479:9,584,221...9,610,420 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:21,881,692...21,906,564
Ensembl chrNW_004936474:21,881,712...21,906,569 		JBrowse link
G Snapin SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
MGI		 PMID:20920792 GO_REF:0000107 NCBI chrNW_004936580:3,449,585...3,464,709
Ensembl chrNW_004936580:3,462,987...3,464,214 		JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chrNW_004936761:1,663,099...1,689,580
Ensembl chrNW_004936761:1,662,738...1,685,156 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,512,866...4,517,404
Ensembl chrNW_004936538:4,511,941...4,517,498 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936567:3,232,628...3,250,596
Ensembl chrNW_004936567:3,225,511...3,250,684 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,955,334...11,967,338
Ensembl chrNW_004936501:11,955,184...11,967,436 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:38,612,450...38,952,150
Ensembl chrNW_004936471:38,612,427...38,952,199 		JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:7,094,949...7,139,961
Ensembl chrNW_004936518:7,095,038...7,137,277 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:22,239,093...22,254,028
Ensembl chrNW_004936477:22,239,093...22,254,439 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chrNW_004936864:117,510...119,612 JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936515:2,885,522...2,995,763
Ensembl chrNW_004936515:2,885,522...2,995,709 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936559:7,177,887...7,312,660
Ensembl chrNW_004936559:7,177,904...7,312,741 		JBrowse link
G Acp2 acid phosphatase 2, lysosomal acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9228031)
(PMID:15604265)		 MGI
TreeGrafter		 PMID:9228031 PMID:15604265 GO_REF:0000118 NCBI chrNW_004936562:1,952,581...1,960,327
Ensembl chrNW_004936562:1,952,536...1,960,327 		JBrowse link
G Acp3 acid phosphatase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936529:5,661,772...5,723,108
Ensembl chrNW_004936529:5,661,702...5,725,363 		JBrowse link
G Acp4 acid phosphatase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936889:510,667...515,831
Ensembl chrNW_004936889:510,667...515,075 		JBrowse link
G Aktip AKT interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:6,139,875...6,150,132
Ensembl chrNW_004936475:6,139,875...6,150,130 		JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30786955), (PMID:9931340) Ensembl
MGI		 PMID:9931340 PMID:30786955 GO_REF:0000107 NCBI chrNW_004936549:5,964,240...6,205,245
Ensembl chrNW_004936549:5,965,143...6,204,379 		JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:37871017) MGI
Ensembl		 PMID:37871017 GO_REF:0000107 NCBI chrNW_004936765:1,112,333...1,123,244
Ensembl chrNW_004936765:1,111,882...1,123,316 		JBrowse link
G Arsg arylsulfatase G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26975023) MGI
Ensembl		 PMID:26975023 GO_REF:0000107 NCBI chrNW_004936541:7,664,241...7,782,762
Ensembl chrNW_004936541:7,703,214...7,782,799 		JBrowse link
G Becn1 beclin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18497889) Ensembl
MGI		 PMID:18497889 GO_REF:0000107 NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151 		JBrowse link
G Chmp5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO (PMID:16567502) MGI PMID:16567502 NCBI chrNW_004936524:1,804,643...1,820,491 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10440905)
(PMID:15588329)
(PMID:10191119), (PMID:10527801)		 Ensembl
TreeGrafter
MGI		 PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936501:11,955,334...11,967,338
Ensembl chrNW_004936501:11,955,184...11,967,436 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15459177) Ensembl
TreeGrafter
MGI		 PMID:15459177 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936511:4,283,016...4,291,968
Ensembl chrNW_004936511:4,283,009...4,292,376 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26681805), (PMID:9600738) Ensembl
TreeGrafter
MGI		 PMID:9600738 PMID:26681805 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:28,069,058...28,084,607
Ensembl chrNW_004936471:28,070,462...28,084,648 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) Ensembl
MGI		 PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 NCBI chrNW_004936615:993,092...999,976
Ensembl chrNW_004936615:985,634...1,003,172 		JBrowse link
G Clvs1 clavesin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936496:11,814,627...12,008,233
Ensembl chrNW_004936496:11,812,646...12,008,355 		JBrowse link
G Clvs2 clavesin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936802:872,224...936,660
Ensembl chrNW_004936802:872,577...936,649 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004936481:18,523,022...18,531,227 JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936842:280,718...306,311
Ensembl chrNW_004936842:280,718...306,285 		JBrowse link
G Gaa alpha glucosidase involved_in
acts_upstream_of_or_within		 ISO (PMID:7717400)
(PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)
(PMID:15169761), (PMID:9668092)		 BHF-UCL
MGI		 PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 More... NCBI chrNW_004936594:4,125,595...4,142,261 JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,715,869...4,720,752
Ensembl chrNW_004936580:4,715,408...4,720,798 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:12,233,943...12,310,014
Ensembl chrNW_004936492:12,233,992...12,308,690 		JBrowse link
G Grn granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chrNW_004936541:793,548...800,271
Ensembl chrNW_004936541:793,523...800,217 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7937929), (PMID:9103204)
(PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)
(PMID:8896570), (PMID:9184660)
(PMID:8747922)		 Ensembl
MGI		 PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 NCBI chrNW_004936471:31,712,485...31,738,273
Ensembl chrNW_004936471:31,709,491...31,738,245 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8789434), (PMID:9645704)
(PMID:8896570), (PMID:9184660)		 Ensembl
MGI		 PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 NCBI chrNW_004936549:1,918,482...1,943,665
Ensembl chrNW_004936549:1,917,327...1,943,691 		JBrowse link
G Hook1 hook microtubule tethering protein 1 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004936522:2,102,787...2,159,525 JBrowse link
G Hook2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:1,869,622...1,879,213
Ensembl chrNW_004936659:1,869,622...1,879,213 		JBrowse link
G Hook3 hook microtubule tethering protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937108:873...110,949
Ensembl chrNW_004937108:60...110,939 		JBrowse link
G Hps1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chrNW_004936636:1,407,666...1,430,683
Ensembl chrNW_004936636:1,410,589...1,430,124 		JBrowse link
G Hps4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936657:1,075,300...1,104,328
Ensembl chrNW_004936657:1,075,261...1,103,055 		JBrowse link
G Hsd17b1 hydroxysteroid 17-beta dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29180785) Ensembl
MGI		 PMID:29180785 GO_REF:0000107 NCBI chrNW_004936490:17,312,390...17,314,423
Ensembl chrNW_004936490:17,312,390...17,314,409 		JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19751987)
(PMID:9097952)		 MGI PMID:9097952 PMID:19751987 NCBI chrNW_004936477:22,200,471...22,215,473
Ensembl chrNW_004936477:22,200,474...22,215,077 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936498:1,446,794...1,459,590
Ensembl chrNW_004936498:1,442,754...1,459,673 		JBrowse link
G LOC101960702 lysosomal acid lipase/cholesteryl ester hydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:4,975,296...5,008,938
Ensembl chrNW_004936601:4,975,211...5,008,962 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:628,469...761,117
Ensembl chrNW_004936607:626,991...761,123 		JBrowse link
G Lyset lysosomal enzyme trafficking factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,113,681...1,115,446
Ensembl chrNW_004936733:1,113,755...1,118,094 		JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)
(PMID:9368050)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chrNW_004936484:16,750,976...16,915,999
Ensembl chrNW_004936484:16,763,511...16,916,022 		JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:3,696,506...3,751,558
Ensembl chrNW_004936641:3,696,536...3,751,598 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:35025759)
(PMID:24423645), (PMID:35025759)
(PMID:26681805)		 Ensembl
MGI		 PMID:24423645 PMID:26681805 PMID:35025759 GO_REF:0000107 NCBI chrNW_004936642:2,745,889...2,833,286
Ensembl chrNW_004936642:2,801,908...2,832,830 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342 		JBrowse link
G Myo7a myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:5,758,572...5,824,526
Ensembl chrNW_004936498:5,751,779...5,824,378 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) Ensembl
MGI		 PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 GO_REF:0000107 NCBI chrNW_004936490:17,305,033...17,312,167
Ensembl chrNW_004936490:17,304,586...17,314,521 		JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221) MGI
Ensembl		 PMID:25365221 GO_REF:0000107 NCBI chrNW_004936580:1,495,833...1,523,307
Ensembl chrNW_004936580:1,495,833...1,523,276 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16542649)
(PMID:16368712)		 Ensembl
MGI		 PMID:16368712 PMID:16542649 GO_REF:0000107 NCBI chrNW_004936474:21,881,692...21,906,564
Ensembl chrNW_004936474:21,881,712...21,906,569 		JBrowse link
G Snapin SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
TreeGrafter
MGI		 PMID:20920792 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936580:3,449,585...3,464,709
Ensembl chrNW_004936580:3,462,987...3,464,214 		JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:25365221)
(PMID:37871017)
(PMID:28237315), (PMID:31637311)
(PMID:26284655)		 MGI PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 PMID:37871017 NCBI chrNW_004936471:7,540,647...7,618,783 JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:933,572...945,717
Ensembl chrNW_004936721:933,404...945,725 		JBrowse link
G Tfeb transcription factor EB involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31637311) Ensembl
MGI		 PMID:31637311 GO_REF:0000107 NCBI chrNW_004936476:18,189,096...18,233,622
Ensembl chrNW_004936476:18,189,041...18,233,701 		JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25066864) Ensembl
TreeGrafter
MGI		 PMID:25066864 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936761:1,663,099...1,689,580
Ensembl chrNW_004936761:1,662,738...1,685,156 		JBrowse link
G Tpcn2 two pore segment channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:1,301,937...1,343,046
Ensembl chrNW_004936599:1,318,169...1,343,106 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15483130) Ensembl
MGI		 PMID:15483130 GO_REF:0000107 NCBI chrNW_004936842:669,869...676,706
Ensembl chrNW_004936842:669,863...676,720 		JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:4,289,487...4,297,634
Ensembl chrNW_004936471:4,289,415...4,298,852 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:50,476...77,797
Ensembl chrNW_004936475:50,321...78,097 		JBrowse link
G Washc5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30061306) Ensembl
MGI		 PMID:30061306 GO_REF:0000107 NCBI chrNW_004936470:22,667,354...22,725,538
Ensembl chrNW_004936470:22,667,127...22,725,749 		JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221)
(PMID:37871017)		 MGI
Ensembl		 PMID:25365221 PMID:37871017 GO_REF:0000107 NCBI chrNW_004936495:11,132,025...11,191,446
Ensembl chrNW_004936495:11,134,138...11,190,863 		JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) UniProt PMID:23434374 NCBI chrNW_004936772:43...7,099 JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936712:1,023,994...1,044,727
Ensembl chrNW_004936712:1,023,989...1,044,728 		JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151 		JBrowse link
G Flcn folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936741:881,150...901,296
Ensembl chrNW_004936741:880,736...901,468 		JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:3,329,097...3,428,170
Ensembl chrNW_004936647:3,329,103...3,428,242 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:12,338,542...12,344,236
Ensembl chrNW_004936501:12,338,542...12,344,265 		JBrowse link
G Myo7a myosin VIIA involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743369) Ensembl
MGI		 PMID:12743369 GO_REF:0000107 NCBI chrNW_004936498:5,758,572...5,824,526
Ensembl chrNW_004936498:5,751,779...5,824,378 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11544318) Ensembl
MGI		 PMID:11544318 GO_REF:0000107 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765 		JBrowse link
G Srpx sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19368996) Ensembl
TreeGrafter
MGI		 PMID:19368996 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936502:5,010,692...5,107,221
Ensembl chrNW_004936502:5,010,682...5,107,254 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,955,334...11,967,338
Ensembl chrNW_004936501:11,955,184...11,967,436 		JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936577:4,430,939...4,475,186
Ensembl chrNW_004936577:4,430,898...4,475,212 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,955,334...11,967,338
Ensembl chrNW_004936501:11,955,184...11,967,436 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936493:7,193,726...7,225,415
Ensembl chrNW_004936493:7,193,709...7,228,625 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936950:242,071...323,204
Ensembl chrNW_004936950:242,522...320,078 		JBrowse link
G Pla2g5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chrNW_004936474:6,131,915...6,150,810
Ensembl chrNW_004936474:6,131,884...6,150,819 		JBrowse link
G Rab20 RAB20, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:2,234,826...2,264,613
Ensembl chrNW_004936472:2,234,873...2,264,622 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936557:6,673,092...6,679,715
Ensembl chrNW_004936557:6,673,065...6,683,468 		JBrowse link
G Rab32 RAB32, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936489:35,620...51,809 JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936538:4,923,740...4,928,798
Ensembl chrNW_004936538:4,923,424...4,928,809 		JBrowse link
G Rab38 RAB38, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936736:1,304,290...1,360,412
Ensembl chrNW_004936736:1,304,185...1,361,221 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936551:750,940...778,432
Ensembl chrNW_004936551:746,936...778,432 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936798:297,600...304,929
Ensembl chrNW_004936798:296,066...305,176 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936557:6,504,562...6,519,219
Ensembl chrNW_004936557:6,504,509...6,519,219 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chrNW_004936581:1,516,199...1,557,992
Ensembl chrNW_004936581:1,512,855...1,559,679 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:22,239,093...22,254,028
Ensembl chrNW_004936477:22,239,093...22,254,439 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:26284655) MGI PMID:26284655 NCBI chrNW_004936471:7,540,647...7,618,783 JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chrNW_004936542:7,577,192...7,581,598
Ensembl chrNW_004936542:7,577,149...7,581,923 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:14,102,080...14,119,592
Ensembl chrNW_004936474:14,102,423...14,119,558 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:793,548...800,271
Ensembl chrNW_004936541:793,523...800,217 		JBrowse link
G LOC101972667 immunity related GTPase M involved_in ISO (PMID:32753672) UniProt PMID:32753672 NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,600,344...4,608,793
Ensembl chrNW_004936588:4,600,344...4,608,787 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:5,576,705...5,614,738
Ensembl chrNW_004936521:5,575,996...5,615,370 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:628,469...761,117
Ensembl chrNW_004936607:626,991...761,123 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:36161949) Ensembl
MGI		 PMID:36161949 GO_REF:0000107 NCBI chrNW_004936501:11,765,236...11,772,403
Ensembl chrNW_004936501:11,764,295...11,772,409 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936553:6,628,131...6,629,027
Ensembl chrNW_004936553:6,628,131...6,629,027 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:17,760,532...17,785,466
Ensembl chrNW_004936482:17,760,384...17,785,587 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:22,239,093...22,254,028
Ensembl chrNW_004936477:22,239,093...22,254,439 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:2,227,305...2,257,725
Ensembl chrNW_004936558:2,227,253...2,257,722 		JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:44,917,462...44,981,773
Ensembl chrNW_004936470:44,914,011...44,982,065 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004936541:793,548...800,271
Ensembl chrNW_004936541:793,523...800,217 		JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:44,917,462...44,981,773
Ensembl chrNW_004936470:44,914,011...44,982,065 		JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chrNW_004936761:1,663,099...1,689,580
Ensembl chrNW_004936761:1,662,738...1,685,156 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160154) Ensembl
MGI		 PMID:23160154 GO_REF:0000107 NCBI chrNW_004936529:264,535...266,451
Ensembl chrNW_004936529:264,468...266,422 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16121
    cellular process 15173
      cellular component organization or biogenesis 6527
        cellular component organization 6330
          organelle organization 3520
            vacuole organization 218
              lytic vacuole organization 96
                lysosome organization + 96
paths to the root