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ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis

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lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:14,952,313...14,975,678
Ensembl chrNW_004624762:14,952,002...14,975,900 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004624732:14,469,377...14,474,540
Ensembl chrNW_004624732:14,466,079...14,474,561 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004624751:23,395,284...23,404,798
Ensembl chrNW_004624751:23,396,789...23,404,906 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004624781:4,866,896...4,879,321
Ensembl chrNW_004624781:4,866,927...4,879,321 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004624826:5,593,190...5,605,946
Ensembl chrNW_004624826:5,589,791...5,605,893 		JBrowse link
G Grn granulin precursor involved_in ISO (PMID:28073925) UniProt PMID:28073925 NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004624793:661,322...675,603
Ensembl chrNW_004624793:661,342...675,675 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004624931:297,864...343,314
Ensembl chrNW_004624931:298,328...343,915 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:22,542,892...22,577,077
Ensembl chrNW_004624764:22,543,857...22,577,121 		JBrowse link
G Snapin SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
MGI		 PMID:20920792 GO_REF:0000107 NCBI chrNW_004624885:3,490,321...3,491,963
Ensembl chrNW_004624885:3,490,321...3,491,946 		JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chrNW_004624827:7,015,267...7,043,853
Ensembl chrNW_004624827:7,014,842...7,041,871 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:961,888...965,911
Ensembl chrNW_004624786:961,890...966,430 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chrNW_004624807:9,525,770...9,544,757
Ensembl chrNW_004624807:9,525,855...9,544,757 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chrNW_004624896:2,163,043...2,432,016
Ensembl chrNW_004624896:2,163,468...2,415,432 		JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in ISO (MGI:7338895|PMID:35469906)
(PMID:32966160)		 UniProt PMID:32966160 PMID:35469906 MGI:7338895 NCBI chrNW_004624759:20,640,407...20,701,790
Ensembl chrNW_004624759:20,673,033...20,701,361 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chrNW_004624755:26,190,547...26,200,512
Ensembl chrNW_004624755:26,190,547...26,207,793 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chrNW_004624937:857,795...871,089 JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) involved_in ISO (PMID:32172343) UniProt PMID:32172343 NCBI chrNW_004624733:28,618,696...28,944,804
Ensembl chrNW_004624733:28,841,329...28,946,717 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:15163665) BHF-UCL PMID:15163665 NCBI chrNW_004624758:6,449,583...6,590,244
Ensembl chrNW_004624758:6,449,629...6,588,664 		JBrowse link
G Acp2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9228031)
(PMID:15604265)		 TreeGrafter
MGI		 PMID:9228031 PMID:15604265 GO_REF:0000118 NCBI chrNW_004624767:1,473,186...1,481,395
Ensembl chrNW_004624767:1,473,205...1,485,345 		JBrowse link
G Acp3 acid phosphatase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:8,375,429...8,441,375
Ensembl chrNW_004624730:8,375,258...8,432,302 		JBrowse link
G Acp4 acid phosphatase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,896,782...3,901,312
Ensembl chrNW_004624832:3,897,819...3,901,293 		JBrowse link
G Aktip AKT interacting protein involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004624757:3,265,492...3,295,406
Ensembl chrNW_004624757:3,265,389...3,294,735 		JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:30786955), (PMID:9931340) MGI PMID:9931340 PMID:30786955 NCBI chrNW_004624869:2,459,370...2,741,529
Ensembl chrNW_004624869:2,459,947...2,741,328 		JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within ISO (PMID:37871017) MGI PMID:37871017 NCBI chrNW_004624740:28,509,979...28,527,813
Ensembl chrNW_004624740:28,509,230...28,527,519 		JBrowse link
G Arsg arylsulfatase G acts_upstream_of_or_within ISO (PMID:26975023) MGI PMID:26975023 NCBI chrNW_004624870:3,363,087...3,487,197
Ensembl chrNW_004624870:3,400,638...3,486,777 		JBrowse link
G Becn1 beclin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18497889) Ensembl
MGI		 PMID:18497889 GO_REF:0000107 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Chmp5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO (PMID:16567502) MGI PMID:16567502 NCBI chrNW_004624736:38,025,247...38,044,808 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15588329)
(PMID:10440905)
(PMID:10191119), (PMID:10527801)		 TreeGrafter
MGI		 PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 GO_REF:0000118 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15459177) TreeGrafter
MGI		 PMID:15459177 GO_REF:0000118 NCBI chrNW_004624751:23,395,284...23,404,798
Ensembl chrNW_004624751:23,396,789...23,404,906 		JBrowse link
G Cln6 CLN6 transmembrane ER protein acts_upstream_of_or_within ISO (PMID:26681805), (PMID:9600738) MGI PMID:9600738 PMID:26681805 NCBI chrNW_004624781:4,866,896...4,879,321
Ensembl chrNW_004624781:4,866,927...4,879,321 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) Ensembl
MGI		 PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 NCBI chrNW_004624861:960,643...977,292
Ensembl chrNW_004624861:968,219...977,467 		JBrowse link
G Clvs1 clavesin 1 involved_in ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chrNW_004624744:30,423,605...30,680,264
Ensembl chrNW_004624744:30,424,917...30,786,645 		JBrowse link
G Clvs2 clavesin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624798:8,219,972...8,302,159
Ensembl chrNW_004624798:8,219,329...8,302,061 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004624826:5,593,190...5,605,946
Ensembl chrNW_004624826:5,589,791...5,605,893 		JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624817:7,693,944...7,716,857
Ensembl chrNW_004624817:7,693,944...7,708,735 		JBrowse link
G Gaa alpha glucosidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)
(PMID:15169761), (PMID:9668092)		 TreeGrafter
MGI		 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... GO_REF:0000118 NCBI chrNW_004624801:9,217,633...9,235,931
Ensembl chrNW_004624801:9,217,639...9,235,931 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (MGI:5817293|PMID:27378698)
(PMID:27378698)		 UniProt PMID:27378698 MGI:5817293 NCBI chrNW_004624885:2,315,371...2,321,327
Ensembl chrNW_004624885:2,315,142...2,321,327 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO (PMID:21719679) UniProt PMID:21719679 NCBI chrNW_004624750:6,315,949...6,344,919
Ensembl chrNW_004624750:6,315,908...6,343,820 		JBrowse link
G Grn granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165 		JBrowse link
G Hexa hexosaminidase subunit alpha acts_upstream_of_or_within ISO (PMID:7937929), (PMID:9103204)
(PMID:8896570), (PMID:9184660)
(PMID:8747922)
(PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)		 MGI PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... NCBI chrNW_004624781:1,686,818...1,706,044
Ensembl chrNW_004624781:1,686,384...1,714,684 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8789434), (PMID:9645704)
(PMID:8896570), (PMID:9184660)		 Ensembl
MGI		 PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 NCBI chrNW_004624924:195,406...219,232
Ensembl chrNW_004624924:195,175...219,278 		JBrowse link
G Hook1 hook microtubule tethering protein 1 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004624862:540,971...594,087
Ensembl chrNW_004624862:544,156...593,919 		JBrowse link
G Hook2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624901:379,952...391,727
Ensembl chrNW_004624901:378,967...392,027 		JBrowse link
G Hook3 hook microtubule tethering protein 3 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004624780:127,718...237,701
Ensembl chrNW_004624780:127,090...235,648 		JBrowse link
G Hps1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chrNW_004624737:10,008,807...10,042,928
Ensembl chrNW_004624737:10,007,777...10,041,100 		JBrowse link
G Hps4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:3,004,370...3,033,692
Ensembl chrNW_004624747:3,005,509...3,032,037 		JBrowse link
G Hsd17b1 hydroxysteroid 17-beta dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:29180785) MGI PMID:29180785 NCBI chrNW_004624795:1,551,311...1,553,432
Ensembl chrNW_004624795:1,551,311...1,553,493 		JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19751987)
(PMID:9097952)		 MGI PMID:9097952 PMID:19751987 NCBI chrNW_004624755:26,151,302...26,169,324
Ensembl chrNW_004624755:26,154,186...26,169,365 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624817:4,872,630...4,879,217
Ensembl chrNW_004624817:4,872,672...4,890,791 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:25807535)
(PMID:29374543)		 MGI PMID:25807535 PMID:29374543 NCBI chrNW_004624737:49,471...82,981
Ensembl chrNW_004624737:49,371...83,514 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chrNW_004624778:106,594...279,325
Ensembl chrNW_004624778:108,761...279,230 		JBrowse link
G Lyset lysosomal enzyme trafficking factor involved_in ISO (PMID:36096887) UniProt PMID:36096887 NCBI chrNW_004624734:9,616,155...9,618,108
Ensembl chrNW_004624734:9,616,159...9,618,644 		JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:9368050)
(PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chrNW_004624775:14,670,498...14,900,501
Ensembl chrNW_004624775:14,705,693...14,898,660 		JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:3,466,723...3,521,830
Ensembl chrNW_004624746:3,455,995...3,523,262 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:24423645), (PMID:35025759)
(PMID:26681805)
(PMID:35025759)		 MGI PMID:24423645 PMID:26681805 PMID:35025759 NCBI chrNW_004624777:8,831,246...8,877,881
Ensembl chrNW_004624777:8,827,851...8,877,873 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259 		JBrowse link
G Myo7a myosin VIIA involved_in ISO (PMID:16001398) UniProt PMID:16001398 NCBI chrNW_004624863:205,468...283,840
Ensembl chrNW_004624863:205,478...283,839 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) MGI PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 NCBI chrNW_004624795:1,553,582...1,558,110
Ensembl chrNW_004624795:1,553,037...1,558,197 		JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta acts_upstream_of_or_within ISO (PMID:25365221) MGI PMID:25365221 NCBI chrNW_004624772:18,533,603...18,564,160
Ensembl chrNW_004624772:18,532,986...18,564,492 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16368712)
(PMID:16542649)		 Ensembl
MGI		 PMID:16368712 PMID:16542649 GO_REF:0000107 NCBI chrNW_004624764:22,542,892...22,577,077
Ensembl chrNW_004624764:22,543,857...22,577,121 		JBrowse link
G Snapin SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) TreeGrafter
MGI
Ensembl		 PMID:20920792 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624885:3,490,321...3,491,963
Ensembl chrNW_004624885:3,490,321...3,491,946 		JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:28237315), (PMID:31637311)
(PMID:25365221)
(PMID:37871017)
(PMID:26284655)		 MGI PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 PMID:37871017 NCBI chrNW_004624804:11,569,024...11,672,037
Ensembl chrNW_004624804:11,569,150...11,670,373 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in ISO (PMID:24448649) UniProt PMID:24448649 NCBI chrNW_004624893:803,717...817,700
Ensembl chrNW_004624893:803,717...817,705 		JBrowse link
G Tfeb transcription factor EB involved_in
acts_upstream_of_or_within		 ISO (PMID:23434374)
(PMID:22692423), (PMID:32612235), (PMID:32753672), (PMID:35662396)
(PMID:31637311)		 UniProt
MGI		 PMID:22692423 PMID:23434374 PMID:31637311 PMID:32612235 PMID:32753672 More... NCBI chrNW_004624754:17,321,179...17,358,402
Ensembl chrNW_004624754:17,321,162...17,358,524 		JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25066864) TreeGrafter
MGI
Ensembl		 PMID:25066864 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624827:7,015,267...7,043,853
Ensembl chrNW_004624827:7,014,842...7,041,871 		JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chrNW_004624767:17,877,791...17,944,190
Ensembl chrNW_004624767:17,918,080...17,944,653 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15483130) MGI
Ensembl		 PMID:15483130 GO_REF:0000107 NCBI chrNW_004624817:8,104,934...8,111,049
Ensembl chrNW_004624817:8,104,939...8,111,035 		JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624804:8,148,920...8,157,552
Ensembl chrNW_004624804:8,148,180...8,157,552 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chrNW_004624914:160,483...188,534
Ensembl chrNW_004624914:160,483...188,490 		JBrowse link
G Washc5 WASH complex subunit 5 acts_upstream_of_or_within ISO (PMID:30061306) MGI PMID:30061306 NCBI chrNW_004624735:30,166,617...30,223,404
Ensembl chrNW_004624735:30,166,623...30,223,404 		JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within ISO (PMID:37871017)
(PMID:25365221)		 MGI PMID:25365221 PMID:37871017 NCBI chrNW_004624734:33,175,080...33,240,484
Ensembl chrNW_004624734:33,175,041...33,238,664 		JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) ParkinsonsUK-UCL PMID:16554368 NCBI chrNW_004624749:16,738,538...16,772,553
Ensembl chrNW_004624749:16,738,416...16,772,391 		JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Flcn folliculin involved_in ISO (PMID:37079666) UniProt PMID:37079666 NCBI chrNW_004624849:4,157,683...4,179,724 JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO (PMID:37079666) UniProt PMID:37079666 NCBI chrNW_004624733:40,263,760...40,396,183
Ensembl chrNW_004624733:40,263,898...40,393,690 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:12132654) UniProt PMID:12132654 NCBI chrNW_004624782:13,106,416...13,111,394
Ensembl chrNW_004624782:13,105,153...13,111,357 		JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO (PMID:12743369) MGI PMID:12743369 NCBI chrNW_004624863:205,468...283,840
Ensembl chrNW_004624863:205,478...283,839 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:11544318) MGI PMID:11544318 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Srpx sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19368996) TreeGrafter
MGI		 PMID:19368996 GO_REF:0000118 NCBI chrNW_004624762:17,240,899...17,347,430
Ensembl chrNW_004624762:17,240,816...17,347,523 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP ribosylation factor like GTPase 8B involved_in ISO (PMID:21802320) UniProt PMID:21802320 NCBI chrNW_004624773:15,785,883...15,833,832
Ensembl chrNW_004624773:15,785,339...15,832,668 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624738:7,265,899...7,306,848
Ensembl chrNW_004624738:7,265,907...7,306,822 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624765:7,684,770...7,806,381
Ensembl chrNW_004624765:7,681,875...7,790,704 		JBrowse link
G Pla2g5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chrNW_004624764:5,196,215...5,207,138
Ensembl chrNW_004624764:5,196,215...5,207,232 		JBrowse link
G Rab20 RAB20, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624793:2,180,803...2,199,420
Ensembl chrNW_004624793:2,180,419...2,198,962 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624807:5,478,570...5,483,473
Ensembl chrNW_004624807:5,478,707...5,483,475 		JBrowse link
G Rab32 RAB32, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624753:7,900,027...7,917,944
Ensembl chrNW_004624753:7,900,267...7,917,854 		JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624786:1,286,886...1,291,582
Ensembl chrNW_004624786:1,286,887...1,291,419 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624784:2,679,281...2,709,514
Ensembl chrNW_004624784:2,679,225...2,710,545 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004625042:56,509...112,519
Ensembl chrNW_004625042:56,517...112,612 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624807:5,307,361...5,334,578
Ensembl chrNW_004624807:5,307,440...5,334,945 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chrNW_004624926:722,201...765,834
Ensembl chrNW_004624926:722,224...765,033 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (MGI:5693670|PMID:26317472) UniProt PMID:26317472 MGI:5693670 NCBI chrNW_004624755:26,190,547...26,200,512
Ensembl chrNW_004624755:26,190,547...26,207,793 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:26284655) MGI PMID:26284655 NCBI chrNW_004624804:11,569,024...11,672,037
Ensembl chrNW_004624804:11,569,150...11,670,373 		JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chrNW_004624880:2,070,410...2,075,069
Ensembl chrNW_004624880:2,070,523...2,079,421 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISO (MGI:5905514|PMID:28073925)
(PMID:28073925)		 UniProt PMID:28073925 MGI:5905514 NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:32753672) UniProt PMID:32753672 NCBI chrNW_004624733:41,241,488...41,248,162 JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624828:634,318...643,406
Ensembl chrNW_004624828:634,214...643,633 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in ISO (PMID:25720963), (PMID:32753672) UniProt PMID:25720963 PMID:32753672 NCBI chrNW_004624754:7,045,532...7,097,658
Ensembl chrNW_004624754:7,045,532...7,097,652 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chrNW_004624778:106,594...279,325
Ensembl chrNW_004624778:108,761...279,230 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:36161949) MGI
Ensembl		 PMID:36161949 GO_REF:0000107 NCBI chrNW_004624782:12,799,850...12,807,159
Ensembl chrNW_004624782:12,799,038...12,807,121 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO (PMID:23569283) UniProt PMID:23569283 NCBI chrNW_004624761:14,039,698...14,066,750
Ensembl chrNW_004624761:14,038,758...14,066,894 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35750034)
(MGI:5693670|PMID:26317472)		 UniProt PMID:26317472 PMID:35750034 MGI:5693670 NCBI chrNW_004624755:26,190,547...26,200,512
Ensembl chrNW_004624755:26,190,547...26,207,793 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:22,458,098...22,478,735
Ensembl chrNW_004624747:22,461,346...22,478,867 		JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chrNW_004624763:4,991,562...5,036,624
Ensembl chrNW_004624763:4,991,548...5,038,138 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165 		JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chrNW_004624763:4,991,562...5,036,624
Ensembl chrNW_004624763:4,991,548...5,038,138 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28728022) MGI
Ensembl		 PMID:28728022 GO_REF:0000107 NCBI chrNW_004624827:7,015,267...7,043,853
Ensembl chrNW_004624827:7,014,842...7,041,871 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:23160154) MGI PMID:23160154 NCBI chrNW_004624730:2,431,270...2,433,010
Ensembl chrNW_004624730:2,431,999...2,432,959 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    cellular process 14346
      cellular component organization or biogenesis 6232
        cellular component organization 6042
          organelle organization 3358
            vacuole organization 212
              lytic vacuole organization 94
                lysosome organization + 94
paths to the root