Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
go back to main search page
Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis


show annotations for term's descendants           Sort by:
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IMP
NAS		 (PMID:32276428)
(PMID:32001091), (PMID:33065002)		 UniProt
ComplexPortal		 PMID:32001091 PMID:32276428 PMID:33065002 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848 		JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in NAS (PMID:33065002) ComplexPortal PMID:33065002 NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582 		JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218 		JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS
IC		 (PMID:32001091), (PMID:33065002) ComplexPortal
UniProt		 PMID:32001091 PMID:33065002 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056 		JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265 		JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847 		JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IMP (PMID:28296633) UniProt PMID:28296633 NCBI chr 2:130,337,933...130,342,681
Ensembl chr 2:130,337,933...130,342,699 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IMP
IBA		 (PMID:11722572) UniProt
GO_Central		 PMID:11722572 GO_REF:0000033 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr15:68,206,992...68,257,211
Ensembl chr15:68,206,992...68,257,211 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805 		JBrowse link
G GRN granulin precursor involved_in IMP (PMID:28073925) UniProt PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IDA (PMID:37390818) UniProt PMID:37390818 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IDA (PMID:37390818) UniProt PMID:37390818 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G RNASEK ribonuclease K involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
MGI		 PMID:20920792 GO_REF:0000107 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IMP (PMID:28296633) UniProt PMID:28296633 NCBI chr17:28,357,647...28,363,683
Ensembl chr17:28,357,642...28,363,683 		JBrowse link
G TMEM9 transmembrane protein 9 involved_in IDA (PMID:30374053) UniProt PMID:30374053 NCBI chr 1:201,134,772...201,171,558
Ensembl chr 1:201,134,772...201,171,574 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IDA (PMID:10924275) UniProt PMID:10924275 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IDA (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chr15:27,719,008...28,099,315
Ensembl chr15:27,754,875...28,099,315 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISS
IEA
IDA		 (PMID:32966160) UniProt
Ensembl		 PMID:32966160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:33,944,623...33,984,693
Ensembl chr 5:33,944,623...33,984,693 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IDA (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,708...228,099,212 		JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IDA (PMID:32172343) UniProt PMID:32172343 NCBI chr 5:160,563,120...160,929,360
Ensembl chr 5:160,563,120...160,852,214 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IDA (PMID:15163665) BHF-UCL PMID:15163665 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ACP2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:15604265)
(PMID:9228031)		 GO_Central
MGI		 PMID:9228031 PMID:15604265 GO_REF:0000033 NCBI chr11:47,239,302...47,248,814
Ensembl chr11:47,239,302...47,248,906 		JBrowse link
G ACP3 acid phosphatase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,302 		JBrowse link
G ACP4 acid phosphatase 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:50,790,415...50,795,219
Ensembl chr19:50,790,415...50,795,219 		JBrowse link
G AKTIP AKT interacting protein involved_in IMP (PMID:18799622) UniProt PMID:18799622 NCBI chr16:53,491,040...53,504,412
Ensembl chr16:53,491,040...53,504,411 		JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30786955), (PMID:9931340) Ensembl
MGI		 PMID:9931340 PMID:30786955 GO_REF:0000107 NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:78,000,522...78,294,762 		JBrowse link
G AP5Z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:37871017) MGI
Ensembl		 PMID:37871017 GO_REF:0000107 NCBI chr 7:4,775,623...4,794,397
Ensembl chr 7:4,775,615...4,794,397 		JBrowse link
G ARSB arylsulfatase B involved_in TAS (PMID:1718978) PINC PMID:1718978 NCBI chr 5:78,777,209...78,985,958
Ensembl chr 5:78,777,209...78,986,087 		JBrowse link
G ARSG arylsulfatase G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26975023) MGI
Ensembl		 PMID:26975023 GO_REF:0000107 NCBI chr17:68,259,170...68,452,019
Ensembl chr17:68,259,182...68,422,731 		JBrowse link
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18497889) Ensembl
MGI		 PMID:18497889 GO_REF:0000107 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16567502) Ensembl
MGI		 PMID:16567502 GO_REF:0000107 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 (PMID:15588329)
(PMID:10191119), (PMID:10527801)
(PMID:10440905)		 UniProt
MGI
GO_Central
Ensembl		 PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15459177) Ensembl
MGI
GO_Central		 PMID:15459177 GO_REF:0000033 GO_REF:0000107 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:26681805), (PMID:9600738) Ensembl
MGI
GO_Central		 PMID:9600738 PMID:26681805 GO_REF:0000033 GO_REF:0000107 NCBI chr15:68,206,992...68,257,211
Ensembl chr15:68,206,992...68,257,211 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) Ensembl
MGI		 PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711 		JBrowse link
G CLVS1 clavesin 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:60,964,848...61,501,629
Ensembl chr 8:61,057,158...61,501,645 		JBrowse link
G CLVS2 clavesin 2 involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805 		JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IMP
IBA		 (PMID:18799622) UniProt
GO_Central		 PMID:18799622 GO_REF:0000033 NCBI chr11:6,211,345...6,234,636
Ensembl chr11:6,211,345...6,234,711 		JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA
IEA		 (PMID:7717400)
(PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)
(PMID:15169761), (PMID:9668092)		 BHF-UCL
MGI
GO_Central
Ensembl		 PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 More... GO_REF:0000033 GO_REF:0000107 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA
IMP		 (PMID:27378698) Ensembl
UniProt		 PMID:27378698 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IMP (PMID:21719679) UniProt PMID:21719679 NCBI chr12:101,745,499...101,830,959
Ensembl chr12:101,745,499...101,830,959 		JBrowse link
G GRN granulin precursor involved_in ISS UniProt GO_REF:0000024 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8896570), (PMID:9184660)
(PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)
(PMID:7937929), (PMID:9103204)
(PMID:8747922)		 Ensembl
MGI		 PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420 		JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8789434), (PMID:9645704)
(PMID:8896570), (PMID:9184660)		 Ensembl
MGI		 PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IMP (PMID:18799622) UniProt PMID:18799622 NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322 		JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IMP (PMID:18799622) UniProt PMID:18799622 NCBI chr19:12,763,003...12,792,350
Ensembl chr19:12,763,003...12,872,740 		JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IMP (PMID:18799622) UniProt PMID:18799622 NCBI chr 8:42,896,978...43,030,535
Ensembl chr 8:42,896,946...43,030,535 		JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 involved_in
acts_upstream_of_or_within		 TAS
ISO		 (PMID:10625677)
(PMID:30786955)		 PINC
MGI		 PMID:10625677 PMID:30786955 NCBI chr10:98,413,948...98,446,935
Ensembl chr10:98,410,939...98,446,963 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IDA (PMID:12663659) UniProt PMID:12663659 NCBI chr22:26,443,109...26,483,863
Ensembl chr22:26,443,107...26,483,931 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29180785) Ensembl
MGI		 PMID:29180785 GO_REF:0000107 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:9097952)
(PMID:19751987)		 MGI PMID:9097952 PMID:19751987 NCBI chr 4:986,997...1,008,351
Ensembl chr 4:986,997...1,004,564 		JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA
ISS		 InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr11:72,097,292...72,103,297
Ensembl chr11:72,085,895...72,103,297 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25807535)
(PMID:29374543)		 Ensembl
MGI		 PMID:25807535 PMID:29374543 GO_REF:0000107 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G LYSET lysosomal enzyme trafficking factor involved_in IMP (PMID:36096887) UniProt PMID:36096887 NCBI chr14:93,184,974...93,188,463
Ensembl chr14:93,184,951...93,188,463 		JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:9368050)
(PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,724 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IMP (PMID:21719679) UniProt PMID:21719679 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24423645), (PMID:35025759)
(PMID:35025759)
(PMID:26681805)		 Ensembl
MGI		 PMID:24423645 PMID:26681805 PMID:35025759 GO_REF:0000107 NCBI chr 4:127,917,732...127,965,963
Ensembl chr 4:127,917,799...127,966,034 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IDA (PMID:22692423) UniProt PMID:22692423 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYO7A myosin VIIA involved_in IDA (PMID:16001398) UniProt PMID:16001398 NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) Ensembl
MGI		 PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 GO_REF:0000107 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449 		JBrowse link
G NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase involved_in TAS (PMID:10551838) PINC PMID:10551838 NCBI chr16:5,024,844...5,033,935
Ensembl chr16:5,024,844...5,034,141 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within IDA (PMID:25365221) MGI PMID:25365221 NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16542649)
(PMID:16368712)		 Ensembl
MGI		 PMID:16368712 PMID:16542649 GO_REF:0000107 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:20920792) Ensembl
MGI
GO_Central		 PMID:20920792 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852 		JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within		 IEA
IDA		 (PMID:25365221) Ensembl
MGI		 PMID:25365221 GO_REF:0000107 NCBI chr15:44,562,696...44,663,662
Ensembl chr15:44,554,818...44,663,688 		JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 involved_in IDA (PMID:24448649) UniProt PMID:24448649 NCBI chr  X:49,028,726...49,043,357
Ensembl chr  X:49,028,726...49,043,410 		JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within		 IMP
ISO
IDA		 (PMID:23434374)
(PMID:31637311)
(PMID:22692423), (PMID:32612235), (PMID:32753672), (PMID:35662396)		 UniProt
MGI		 PMID:22692423 PMID:23434374 PMID:31637311 PMID:32612235 PMID:32753672 More... NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25066864) Ensembl
MGI
GO_Central		 PMID:25066864 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367 		JBrowse link
G TPCN2 two pore segment channel 2 involved_in IGI (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316 		JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:15483130) Ensembl
MGI
UniProt		 PMID:15483130 GO_REF:0000024 GO_REF:0000107 NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448 		JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IDA
IBA		 (PMID:18799622) UniProt
GO_Central		 PMID:18799622 GO_REF:0000033 NCBI chr15:40,894,450...40,903,975
Ensembl chr15:40,894,450...40,903,975 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518 		JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30061306) Ensembl
MGI		 PMID:30061306 GO_REF:0000107 NCBI chr 8:125,024,260...125,091,792
Ensembl chr 8:125,024,260...125,091,819 		JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:25365221) MGI
Ensembl		 PMID:25365221 GO_REF:0000107 NCBI chr14:67,728,892...67,816,590
Ensembl chr14:67,727,374...67,816,590 		JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 involved_in IMP (PMID:23434374) UniProt PMID:23434374 NCBI chr 6:28,349,878...28,369,172
Ensembl chr 6:28,349,947...28,369,172 		JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP1A charged multivesicular body protein 1A involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr16:89,644,435...89,657,708
Ensembl chr16:89,640,816...89,657,738 		JBrowse link
G CHMP1B charged multivesicular body protein 1B involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr18:11,851,413...11,854,444
Ensembl chr18:11,851,413...11,854,444 		JBrowse link
G CHMP2A charged multivesicular body protein 2A involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr19:58,551,566...58,555,105
Ensembl chr19:58,551,452...58,555,105 		JBrowse link
G CHMP2B charged multivesicular body protein 2B involved_in TAS
NAS		 (PMID:21118109)
(PMID:16505166)		 ParkinsonsUK-UCL
ComplexPortal		 PMID:16505166 PMID:21118109 NCBI chr 3:87,227,309...87,255,556
Ensembl chr 3:87,227,271...87,255,556 		JBrowse link
G CHMP3 charged multivesicular body protein 3 involved_in IMP
NAS		 (PMID:16554368)
(PMID:16505166)		 ParkinsonsUK-UCL
ComplexPortal		 PMID:16505166 PMID:16554368 NCBI chr 2:86,503,430...86,563,443
Ensembl chr 2:86,503,430...86,563,479 		JBrowse link
G CHMP4A charged multivesicular body protein 4A involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr14:24,209,615...24,213,488
Ensembl chr14:24,209,615...24,213,830 		JBrowse link
G CHMP4B charged multivesicular body protein 4B involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr20:33,811,348...33,854,366
Ensembl chr20:33,811,348...33,854,366 		JBrowse link
G CHMP4C charged multivesicular body protein 4C involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 8:81,732,448...81,759,515
Ensembl chr 8:81,732,448...81,759,515 		JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070 		JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr17:80,991,841...81,000,133
Ensembl chr17:80,991,598...81,009,517 		JBrowse link
G CHMP7 charged multivesicular body protein 7 involved_in NAS (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 8:23,243,637...23,261,999
Ensembl chr 8:23,243,637...23,262,000 		JBrowse link
G RNF103-CHMP3 RNF103-CHMP3 readthrough involved_in IMP
NAS		 (PMID:16554368)
(PMID:16505166)		 ParkinsonsUK-UCL
ComplexPortal		 PMID:16505166 PMID:16554368 NCBI chr 2:86,503,430...86,721,122
Ensembl chr 2:86,505,668...86,721,122 		JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25561470 GO_REF:0000107 RGD:11561937 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G FLCN folliculin involved_in IDA (PMID:37079666) UniProt PMID:37079666 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188 		JBrowse link
G FNIP1 folliculin interacting protein 1 involved_in IDA (PMID:37079666) UniProt PMID:37079666 NCBI chr 5:131,641,714...131,797,017
Ensembl chr 5:131,641,714...131,797,017 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IDA (PMID:24448649), (PMID:32612235) UniProt PMID:24448649 PMID:32612235 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IMP (PMID:12132654) UniProt PMID:12132654 NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076 		JBrowse link
G MYO7A myosin VIIA involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743369) Ensembl
MGI		 PMID:12743369 GO_REF:0000107 NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11544318) Ensembl
MGI		 PMID:11544318 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G SRPX sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:19368996) Ensembl
MGI
GO_Central		 PMID:19368996 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:38,149,339...38,220,871
Ensembl chr  X:38,149,336...38,220,924 		JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB14 RAB14, member RAS oncogene family involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:121,178,133...121,201,869
Ensembl chr 9:121,178,133...121,223,014 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575 		JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IMP (PMID:21802320) UniProt PMID:21802320 NCBI chr 3:5,122,292...5,180,911
Ensembl chr 3:5,122,249...5,180,911 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA
IBA
IDA		 (PMID:28779020) Ensembl
GO_Central
UniProt		 PMID:28779020 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt PMID:21255211 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722 		JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IMP
IBA		 (PMID:21255211) UniProt
GO_Central		 PMID:21255211 GO_REF:0000033 NCBI chr17:28,714,281...28,718,428
Ensembl chr17:28,714,281...28,718,429 		JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IMP
IBA		 (PMID:21255211) UniProt
GO_Central		 PMID:21255211 GO_REF:0000033 NCBI chr11:107,928,448...107,963,482
Ensembl chr11:107,928,448...107,963,482 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in IMP
IBA		 (PMID:21255211) UniProt
GO_Central		 PMID:21255211 GO_REF:0000033 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
G SYT7 synaptotagmin 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:61,513,714...61,588,387
Ensembl chr11:61,513,714...61,581,148 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656 		JBrowse link
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog involved_in NAS (PMID:27555442) ComplexPortal PMID:27555442 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952 		JBrowse link
G VPS33B VPS33B late endosome and lysosome associated involved_in NAS (PMID:27555442) ComplexPortal PMID:27555442 NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26284655) Ensembl
MGI		 PMID:26284655 GO_REF:0000107 NCBI chr15:44,562,696...44,663,662
Ensembl chr15:44,554,818...44,663,688 		JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9038169 GO_REF:0000107 RGD:10059368 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IDA (PMID:19787053) ARUK-UCL PMID:19787053 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IDA (PMID:28073925) UniProt PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:32753672) UniProt PMID:32753672 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IDA (PMID:25720963) UniProt PMID:25720963 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in IDA (PMID:25720963), (PMID:32753672) UniProt PMID:25720963 PMID:32753672 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:36161949) Ensembl
MGI		 PMID:36161949 GO_REF:0000107 NCBI chr16:28,974,778...28,984,765
Ensembl chr16:28,974,221...28,984,548 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IDA
IBA		 (PMID:31001245) UniProt
GO_Central		 PMID:31001245 GO_REF:0000033 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
G TMEM165 transmembrane protein 165 involved_in IMP (PMID:23569283) UniProt PMID:23569283 NCBI chr 4:55,395,957...55,453,397
Ensembl chr 4:55,395,957...55,453,397 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA
IDA		 (PMID:35750034) Ensembl
UniProt		 PMID:35750034 GO_REF:0000107 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656 		JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IMP (PMID:28013294) UniProt PMID:28013294 NCBI chr12:122,229,564...122,266,494
Ensembl chr12:122,229,564...122,266,502 		JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IMP (PMID:26280656) UniProt PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IMP (PMID:26280656) UniProt PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013 		JBrowse link
G SCARB2 scavenger receptor class B member 2 involved_in TAS (PMID:12356916) ParkinsonsUK-UCL PMID:12356916 NCBI chr 4:76,158,737...76,234,532
Ensembl chr 4:76,158,737...76,234,536 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160154) Ensembl
MGI		 PMID:23160154 GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19777
    cellular process 18349
      cellular component organization or biogenesis 7636
        cellular component organization 7427
          organelle organization 3970
            vacuole organization 248
              lytic vacuole organization 118
                lysosome organization + 118
paths to the root