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ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis


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lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in ISS UniProt GO_REF:0000024 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS UniProt GO_REF:0000024 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 7:30,873,556...30,884,257
Ensembl chr 7:30,873,556...30,883,370 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,678,116...60,695,619
Ensembl chr22:60,678,111...60,694,924 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425 		JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445 		JBrowse link
G TMEM9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 7:2,069,017...2,087,961 JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMACR alpha-methylacyl-CoA racemase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,815,438...73,836,016
Ensembl chr 4:73,815,291...73,867,437 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,361,825...32,713,631
Ensembl chr 3:32,361,517...32,713,572 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,838,684...73,868,222
Ensembl chr 4:73,815,291...73,867,437 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr14:835,476...836,424
Ensembl chr14:835,476...836,424 		JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:49,856,489...50,163,033
Ensembl chr 4:49,912,397...50,161,319 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,761,669...60,869,753
Ensembl chr11:60,761,655...60,890,496 		JBrowse link
G ACP2 acid phosphatase 2, lysosomal acts_upstream_of_or_within ISO (PMID:15604265)
(PMID:9228031)		 MGI PMID:9228031 PMID:15604265 NCBI chr18:42,346,207...42,356,447
Ensembl chr18:42,345,608...42,354,352 		JBrowse link
G AKTIP AKT interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:62,253,005...62,263,918
Ensembl chr 2:62,254,320...62,263,337 		JBrowse link
G ANAPC15 anaphase promoting complex subunit 15 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:25,971,680...25,975,556
Ensembl chr21:25,972,458...25,975,558 		JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30786955), (PMID:9931340) Ensembl
MGI		 PMID:9931340 PMID:30786955 GO_REF:0000107 NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258 		JBrowse link
G AP5Z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:37871017) MGI
Ensembl		 PMID:37871017 GO_REF:0000107 NCBI chr 6:12,847,699...12,858,769
Ensembl chr 6:12,847,713...12,858,681 		JBrowse link
G ARSG arylsulfatase G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26975023) MGI
Ensembl		 PMID:26975023 GO_REF:0000107 NCBI chr 9:15,048,563...15,115,095
Ensembl chr 9:15,048,588...15,115,101 		JBrowse link
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18497889) Ensembl
MGI		 PMID:18497889 GO_REF:0000107 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G CHMP5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO (PMID:16567502) MGI PMID:16567502 NCBI chr11:50,363,488...50,376,081 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10440905)
(PMID:15588329)
(PMID:10191119), (PMID:10527801)		 Ensembl
MGI
GO_Central		 PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:15459177) GO_Central
MGI		 PMID:15459177 GO_REF:0000033 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:26681805), (PMID:9600738) GO_Central
MGI		 PMID:9600738 PMID:26681805 GO_REF:0000033 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) MGI PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 NCBI chr37:30,863,098...30,885,831
Ensembl chr37:30,867,479...30,884,895 		JBrowse link
G CLVS1 clavesin 1 involved_in ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chr29:11,638,550...11,811,853
Ensembl chr29:11,638,024...11,812,396 		JBrowse link
G CLVS2 clavesin 2 involved_in ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chr 1:62,217,473...62,286,853
Ensembl chr 1:62,217,837...62,282,449 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 7:30,873,556...30,884,257
Ensembl chr 7:30,873,556...30,883,370 		JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,547,361...29,570,900
Ensembl chr21:29,547,522...29,566,536 		JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)
(PMID:15169761), (PMID:9668092)		 Ensembl
MGI		 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... GO_REF:0000107 NCBI chr 9:1,601,092...1,615,582
Ensembl chr 9:1,601,121...1,656,597 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:40,659,108...40,724,498
Ensembl chr15:40,631,279...40,704,365 		JBrowse link
G GRN granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8896570), (PMID:9184660)
(PMID:7937929), (PMID:9103204)
(PMID:8747922)
(PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)		 Ensembl
MGI		 PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 NCBI chr30:35,836,788...35,862,525 JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8789434), (PMID:9645704)
(PMID:8896570), (PMID:9184660)		 Ensembl
MGI		 PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 NCBI chr 2:57,221,809...57,248,432
Ensembl chr 2:57,222,186...57,248,417 		JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:49,994,930...50,060,513
Ensembl chr 5:49,998,241...50,060,525 		JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,367,450...49,383,109
Ensembl chr20:49,367,876...49,382,813 		JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,791,198...22,940,168
Ensembl chr16:22,784,267...22,901,991 		JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chr28:11,547,457...11,572,248
Ensembl chr28:11,547,741...11,571,613 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:20,131,658...20,157,532
Ensembl chr26:19,933,281...20,157,058 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29180785) Ensembl
MGI		 PMID:29180785 GO_REF:0000107 NCBI chr 9:20,402,124...20,407,143
Ensembl chr 9:20,405,019...20,406,792 		JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:9097952)
(PMID:19751987)		 MGI PMID:9097952 PMID:19751987 NCBI chr 3:91,517,225...91,534,593
Ensembl chr 3:91,522,035...91,534,593 		JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr21:25,981,170...25,986,942
Ensembl chr21:25,981,254...25,996,432 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:29374543)
(PMID:25807535)		 MGI PMID:25807535 PMID:29374543 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436 		JBrowse link
G LOC119877912 beclin-1 involved_in IEA Ensembl GO_REF:0000107
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G LYSET lysosomal enzyme trafficking factor involved_in ISO (PMID:36096887) UniProt PMID:36096887 NCBI chr 8:62,394,838...62,398,637
Ensembl chr 8:62,394,832...62,395,881 		JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:9368050)
(PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chr 4:4,106,869...4,296,042
Ensembl chr 4:4,089,837...4,294,593 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:68,228,176...68,281,175
Ensembl chr 5:68,228,238...68,280,515 		JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24423645), (PMID:35025759)
(PMID:35025759)
(PMID:26681805)		 Ensembl
MGI		 PMID:24423645 PMID:26681805 PMID:35025759 GO_REF:0000107 NCBI chr19:12,905,336...13,030,901
Ensembl chr19:12,982,394...13,020,083 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G MYO7A myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:21,539,735...21,624,063
Ensembl chr21:21,539,785...21,624,279 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) Ensembl
MGI		 PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 GO_REF:0000107 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221) MGI
Ensembl		 PMID:25365221 GO_REF:0000107 NCBI chr17:60,359,545...60,386,093
Ensembl chr17:60,360,236...60,384,778 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16542649)
(PMID:16368712)		 Ensembl
MGI		 PMID:16368712 PMID:16542649 GO_REF:0000107 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425 		JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323 		JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221)
(PMID:37871017)
(PMID:28237315), (PMID:31637311)
(PMID:26284655)		 MGI
Ensembl		 PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 PMID:37871017 GO_REF:0000107 NCBI chr30:11,233,709...11,305,454
Ensembl chr30:11,233,718...11,305,485 		JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,181,639...42,192,709
Ensembl chr  X:42,183,037...42,193,892 		JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31637311) Ensembl
MGI		 PMID:31637311 GO_REF:0000107 NCBI chr12:10,367,979...10,423,478
Ensembl chr12:10,368,599...10,452,619 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:25066864) MGI PMID:25066864 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333 		JBrowse link
G TPCN2 two pore segment channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15483130) Ensembl
MGI		 PMID:15483130 GO_REF:0000107 NCBI chr21:29,921,764...29,926,974
Ensembl chr21:29,921,764...29,926,986 		JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:8,027,877...8,036,773
Ensembl chr30:8,027,128...8,036,153 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049 		JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30061306) Ensembl
MGI		 PMID:30061306 GO_REF:0000107 NCBI chr13:23,019,422...23,078,073
Ensembl chr13:23,019,636...23,078,280 		JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221)
(PMID:37871017)		 MGI
Ensembl		 PMID:25365221 PMID:37871017 GO_REF:0000107 NCBI chr 8:41,714,654...41,777,996
Ensembl chr 8:41,715,485...41,777,422 		JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP3 charged multivesicular body protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,600,793...38,658,368 JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711 		JBrowse link
G FNIP1 folliculin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:19,979,294...20,134,341
Ensembl chr11:19,979,163...20,134,229 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818 		JBrowse link
G MYO7A myosin VIIA involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743369) Ensembl
MGI		 PMID:12743369 GO_REF:0000107 NCBI chr21:21,539,735...21,624,063
Ensembl chr21:21,539,785...21,624,279 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11544318) Ensembl
MGI		 PMID:11544318 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G SRPX sushi repeat containing protein X-linked acts_upstream_of_or_within ISO (PMID:19368996) MGI PMID:19368996 NCBI chr  X:32,905,380...33,017,642
Ensembl chr  X:32,745,020...33,330,841 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:12,479,680...12,525,330
Ensembl chr20:12,481,860...12,525,499 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:16,537,095...16,620,427
Ensembl chr37:16,541,562...16,619,554 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983 		JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:58,825,147...58,853,921
Ensembl chr22:58,825,667...58,853,667 		JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,909,843...42,913,935
Ensembl chr 9:42,910,011...42,913,985 		JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,516,541...24,546,743
Ensembl chr 5:24,519,240...24,546,606 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:2,704,716...2,776,518
Ensembl chr20:2,704,752...2,826,636 		JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26284655) Ensembl
MGI		 PMID:26284655 GO_REF:0000107 NCBI chr30:11,233,709...11,305,454
Ensembl chr30:11,233,718...11,305,485 		JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:32753672) UniProt PMID:32753672 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:23,976,023...24,028,139
Ensembl chr 4:23,977,317...24,028,153 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (PMID:36161949) MGI PMID:36161949 NCBI chr 6:18,450,019...18,458,456
Ensembl chr 6:18,412,219...18,459,438 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chr  X:25,664,361...25,679,044 JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,658,408...47,683,519
Ensembl chr13:47,658,330...47,682,866 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930 		JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,090,669...7,119,913 JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160154) Ensembl
MGI		 PMID:23160154 GO_REF:0000107 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    cellular process 15926
      cellular component organization or biogenesis 6330
        cellular component organization 6135
          organelle organization 3327
            vacuole organization 198
              lytic vacuole organization 91
                lysosome organization + 91
paths to the root